Microbial production of beneficial indoleamines (serotonin and melatonin) with potential application to biotechnological products for human health

Autores
Danilovich, Mariana Elizabeth; Alberto, Maria Rosa; Juárez Tomás, María Silvina
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Micro-organisms have showed the ability to produce biologically active compounds associated with neurotransmission in higher organisms. In particular, serotonin- and melatonin-producing microbes are valuable sources for the development of eco-friendly bioproducts. Serotonin and melatonin are indoleamines that have received special attention due to their positive effects on human health. These biomolecules exert a critical role in several physiological or pathological processes, including some mental and neurological disorders. This article includes a review of the microbial production of serotonin and melatonin, their functions in micro-organisms and their potential uses as therapeutic and/or preventive agents to improve human health. A description of the quantification methods employed to detect indoleamines and the evidence found concerning their microbial production at laboratory and industrial scale—for application in biotechnological products—is also provided. The microbial ability to synthesize beneficial indoleamines should be further studied and harnessed, to allow the development of sustainable bioprocesses to produce foods and pharmaceuticals for human health.
Fil: Danilovich, Mariana Elizabeth. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
Fil: Alberto, Maria Rosa. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
Fil: Juárez Tomás, María Silvina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina
Materia
BIOTECHNOLOGICAL PRODUCTS
HUMAN HEALTH
INDOLEAMINES
MICRO-ORGANISMS
SEROTONIN AND MELATONIN BIOSYNTHESIS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/143744
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Microbial production of beneficial indoleamines (serotonin and melatonin) with potential application to biotechnological products for human healthDanilovich, Mariana ElizabethAlberto, Maria RosaJuárez Tomás, María SilvinaBIOTECHNOLOGICAL PRODUCTSHUMAN HEALTHINDOLEAMINESMICRO-ORGANISMSSEROTONIN AND MELATONIN BIOSYNTHESIShttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Micro-organisms have showed the ability to produce biologically active compounds associated with neurotransmission in higher organisms. In particular, serotonin- and melatonin-producing microbes are valuable sources for the development of eco-friendly bioproducts. Serotonin and melatonin are indoleamines that have received special attention due to their positive effects on human health. These biomolecules exert a critical role in several physiological or pathological processes, including some mental and neurological disorders. This article includes a review of the microbial production of serotonin and melatonin, their functions in micro-organisms and their potential uses as therapeutic and/or preventive agents to improve human health. A description of the quantification methods employed to detect indoleamines and the evidence found concerning their microbial production at laboratory and industrial scale—for application in biotechnological products—is also provided. The microbial ability to synthesize beneficial indoleamines should be further studied and harnessed, to allow the development of sustainable bioprocesses to produce foods and pharmaceuticals for human health.Fil: Danilovich, Mariana Elizabeth. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; ArgentinaFil: Alberto, Maria Rosa. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; ArgentinaFil: Juárez Tomás, María Silvina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; ArgentinaWiley Blackwell Publishing, Inc2021-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/143744Danilovich, Mariana Elizabeth; Alberto, Maria Rosa; Juárez Tomás, María Silvina; Microbial production of beneficial indoleamines (serotonin and melatonin) with potential application to biotechnological products for human health; Wiley Blackwell Publishing, Inc; Journal of Applied Microbiology; 131; 4; 10-2021; 1668-16821364-50721365-2672CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1111/jam.15012info:eu-repo/semantics/altIdentifier/url/https://sfamjournals.onlinelibrary.wiley.com/doi/10.1111/jam.15012info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:37:41Zoai:ri.conicet.gov.ar:11336/143744instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:37:41.949CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Microbial production of beneficial indoleamines (serotonin and melatonin) with potential application to biotechnological products for human health
title Microbial production of beneficial indoleamines (serotonin and melatonin) with potential application to biotechnological products for human health
spellingShingle Microbial production of beneficial indoleamines (serotonin and melatonin) with potential application to biotechnological products for human health
Danilovich, Mariana Elizabeth
BIOTECHNOLOGICAL PRODUCTS
HUMAN HEALTH
INDOLEAMINES
MICRO-ORGANISMS
SEROTONIN AND MELATONIN BIOSYNTHESIS
title_short Microbial production of beneficial indoleamines (serotonin and melatonin) with potential application to biotechnological products for human health
title_full Microbial production of beneficial indoleamines (serotonin and melatonin) with potential application to biotechnological products for human health
title_fullStr Microbial production of beneficial indoleamines (serotonin and melatonin) with potential application to biotechnological products for human health
title_full_unstemmed Microbial production of beneficial indoleamines (serotonin and melatonin) with potential application to biotechnological products for human health
title_sort Microbial production of beneficial indoleamines (serotonin and melatonin) with potential application to biotechnological products for human health
dc.creator.none.fl_str_mv Danilovich, Mariana Elizabeth
Alberto, Maria Rosa
Juárez Tomás, María Silvina
author Danilovich, Mariana Elizabeth
author_facet Danilovich, Mariana Elizabeth
Alberto, Maria Rosa
Juárez Tomás, María Silvina
author_role author
author2 Alberto, Maria Rosa
Juárez Tomás, María Silvina
author2_role author
author
dc.subject.none.fl_str_mv BIOTECHNOLOGICAL PRODUCTS
HUMAN HEALTH
INDOLEAMINES
MICRO-ORGANISMS
SEROTONIN AND MELATONIN BIOSYNTHESIS
topic BIOTECHNOLOGICAL PRODUCTS
HUMAN HEALTH
INDOLEAMINES
MICRO-ORGANISMS
SEROTONIN AND MELATONIN BIOSYNTHESIS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Micro-organisms have showed the ability to produce biologically active compounds associated with neurotransmission in higher organisms. In particular, serotonin- and melatonin-producing microbes are valuable sources for the development of eco-friendly bioproducts. Serotonin and melatonin are indoleamines that have received special attention due to their positive effects on human health. These biomolecules exert a critical role in several physiological or pathological processes, including some mental and neurological disorders. This article includes a review of the microbial production of serotonin and melatonin, their functions in micro-organisms and their potential uses as therapeutic and/or preventive agents to improve human health. A description of the quantification methods employed to detect indoleamines and the evidence found concerning their microbial production at laboratory and industrial scale—for application in biotechnological products—is also provided. The microbial ability to synthesize beneficial indoleamines should be further studied and harnessed, to allow the development of sustainable bioprocesses to produce foods and pharmaceuticals for human health.
Fil: Danilovich, Mariana Elizabeth. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
Fil: Alberto, Maria Rosa. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
Fil: Juárez Tomás, María Silvina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina
description Micro-organisms have showed the ability to produce biologically active compounds associated with neurotransmission in higher organisms. In particular, serotonin- and melatonin-producing microbes are valuable sources for the development of eco-friendly bioproducts. Serotonin and melatonin are indoleamines that have received special attention due to their positive effects on human health. These biomolecules exert a critical role in several physiological or pathological processes, including some mental and neurological disorders. This article includes a review of the microbial production of serotonin and melatonin, their functions in micro-organisms and their potential uses as therapeutic and/or preventive agents to improve human health. A description of the quantification methods employed to detect indoleamines and the evidence found concerning their microbial production at laboratory and industrial scale—for application in biotechnological products—is also provided. The microbial ability to synthesize beneficial indoleamines should be further studied and harnessed, to allow the development of sustainable bioprocesses to produce foods and pharmaceuticals for human health.
publishDate 2021
dc.date.none.fl_str_mv 2021-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/143744
Danilovich, Mariana Elizabeth; Alberto, Maria Rosa; Juárez Tomás, María Silvina; Microbial production of beneficial indoleamines (serotonin and melatonin) with potential application to biotechnological products for human health; Wiley Blackwell Publishing, Inc; Journal of Applied Microbiology; 131; 4; 10-2021; 1668-1682
1364-5072
1365-2672
CONICET Digital
CONICET
url http://hdl.handle.net/11336/143744
identifier_str_mv Danilovich, Mariana Elizabeth; Alberto, Maria Rosa; Juárez Tomás, María Silvina; Microbial production of beneficial indoleamines (serotonin and melatonin) with potential application to biotechnological products for human health; Wiley Blackwell Publishing, Inc; Journal of Applied Microbiology; 131; 4; 10-2021; 1668-1682
1364-5072
1365-2672
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1111/jam.15012
info:eu-repo/semantics/altIdentifier/url/https://sfamjournals.onlinelibrary.wiley.com/doi/10.1111/jam.15012
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844613189117935616
score 13.069144

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