Targeted radionuclide therapy: frontiers in theranostics

Autores
Gallivanone, Francesca; Valente, Mauro Andres; Savi, Annarita; Canevari, Carla; Castiglioni, Isabella
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The concept of targeted radionuclide therapy (TRT) relies on the use of injected nuclear medicine as treating agents, targeted at the cellular or molecular level. The growth of the interest in TRT was stimulated by the advances in radionuclide production and labeling as well as by the improvement in the knowledge of appropriate and specific molecular targets. In recent years, different studies on TRT were focused on the evaluation of radionuclide compounds able to combine imaging of the disease with TRT, in a theranostic approach. This approach is of particular interest towards the personalization of treatments, allowing both the baseline characterization of oncological pathologies and treatment optimization by correct dosimetric calculation as well as therapy monitoring. This paper presents a review of recent literature on TRT, with a particular focus on clinical applications promoting such a theranostic approach, showing the impact of the synergy of diagnostic imaging and therapeutics.
Fil: Gallivanone, Francesca. Consejo Nacional de Investigación; Italia
Fil: Valente, Mauro Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina. Universidad de La Frontera; Chile
Fil: Savi, Annarita. Instituto Científico San Raffaele; Italia
Fil: Canevari, Carla. Instituto Científico San Raffaele; Italia
Fil: Castiglioni, Isabella. Consejo Nacional de Investigación; Italia
Materia
Radionuclide therapy
Cancer
Imaging
Review
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/63817
Acceder
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spelling Targeted radionuclide therapy: frontiers in theranosticsGallivanone, FrancescaValente, Mauro AndresSavi, AnnaritaCanevari, CarlaCastiglioni, IsabellaRadionuclide therapyCancerImagingReviewhttps://purl.org/becyt/ford/1.3https://purl.org/becyt/ford/1The concept of targeted radionuclide therapy (TRT) relies on the use of injected nuclear medicine as treating agents, targeted at the cellular or molecular level. The growth of the interest in TRT was stimulated by the advances in radionuclide production and labeling as well as by the improvement in the knowledge of appropriate and specific molecular targets. In recent years, different studies on TRT were focused on the evaluation of radionuclide compounds able to combine imaging of the disease with TRT, in a theranostic approach. This approach is of particular interest towards the personalization of treatments, allowing both the baseline characterization of oncological pathologies and treatment optimization by correct dosimetric calculation as well as therapy monitoring. This paper presents a review of recent literature on TRT, with a particular focus on clinical applications promoting such a theranostic approach, showing the impact of the synergy of diagnostic imaging and therapeutics.Fil: Gallivanone, Francesca. Consejo Nacional de Investigación; ItaliaFil: Valente, Mauro Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina. Universidad de La Frontera; ChileFil: Savi, Annarita. Instituto Científico San Raffaele; ItaliaFil: Canevari, Carla. Instituto Científico San Raffaele; ItaliaFil: Castiglioni, Isabella. Consejo Nacional de Investigación; ItaliaLandmark2017-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/63817Gallivanone, Francesca; Valente, Mauro Andres; Savi, Annarita; Canevari, Carla; Castiglioni, Isabella; Targeted radionuclide therapy: frontiers in theranostics; Landmark; Frontiers in bioscience (Landmark edition); 22; 1-6-2017; 1750-17591093-4715CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.2741/4569info:eu-repo/semantics/altIdentifier/url/https://www.bioscience.org/2017/v22/af/4569/list.htminfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T12:10:23Zoai:ri.conicet.gov.ar:11336/63817instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 12:10:23.961CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Targeted radionuclide therapy: frontiers in theranostics
title Targeted radionuclide therapy: frontiers in theranostics
spellingShingle Targeted radionuclide therapy: frontiers in theranostics
Gallivanone, Francesca
Radionuclide therapy
Cancer
Imaging
Review
title_short Targeted radionuclide therapy: frontiers in theranostics
title_full Targeted radionuclide therapy: frontiers in theranostics
title_fullStr Targeted radionuclide therapy: frontiers in theranostics
title_full_unstemmed Targeted radionuclide therapy: frontiers in theranostics
title_sort Targeted radionuclide therapy: frontiers in theranostics
dc.creator.none.fl_str_mv Gallivanone, Francesca
Valente, Mauro Andres
Savi, Annarita
Canevari, Carla
Castiglioni, Isabella
author Gallivanone, Francesca
author_facet Gallivanone, Francesca
Valente, Mauro Andres
Savi, Annarita
Canevari, Carla
Castiglioni, Isabella
author_role author
author2 Valente, Mauro Andres
Savi, Annarita
Canevari, Carla
Castiglioni, Isabella
author2_role author
author
author
author
dc.subject.none.fl_str_mv Radionuclide therapy
Cancer
Imaging
Review
topic Radionuclide therapy
Cancer
Imaging
Review
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The concept of targeted radionuclide therapy (TRT) relies on the use of injected nuclear medicine as treating agents, targeted at the cellular or molecular level. The growth of the interest in TRT was stimulated by the advances in radionuclide production and labeling as well as by the improvement in the knowledge of appropriate and specific molecular targets. In recent years, different studies on TRT were focused on the evaluation of radionuclide compounds able to combine imaging of the disease with TRT, in a theranostic approach. This approach is of particular interest towards the personalization of treatments, allowing both the baseline characterization of oncological pathologies and treatment optimization by correct dosimetric calculation as well as therapy monitoring. This paper presents a review of recent literature on TRT, with a particular focus on clinical applications promoting such a theranostic approach, showing the impact of the synergy of diagnostic imaging and therapeutics.
Fil: Gallivanone, Francesca. Consejo Nacional de Investigación; Italia
Fil: Valente, Mauro Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina. Universidad de La Frontera; Chile
Fil: Savi, Annarita. Instituto Científico San Raffaele; Italia
Fil: Canevari, Carla. Instituto Científico San Raffaele; Italia
Fil: Castiglioni, Isabella. Consejo Nacional de Investigación; Italia
description The concept of targeted radionuclide therapy (TRT) relies on the use of injected nuclear medicine as treating agents, targeted at the cellular or molecular level. The growth of the interest in TRT was stimulated by the advances in radionuclide production and labeling as well as by the improvement in the knowledge of appropriate and specific molecular targets. In recent years, different studies on TRT were focused on the evaluation of radionuclide compounds able to combine imaging of the disease with TRT, in a theranostic approach. This approach is of particular interest towards the personalization of treatments, allowing both the baseline characterization of oncological pathologies and treatment optimization by correct dosimetric calculation as well as therapy monitoring. This paper presents a review of recent literature on TRT, with a particular focus on clinical applications promoting such a theranostic approach, showing the impact of the synergy of diagnostic imaging and therapeutics.
publishDate 2017
dc.date.none.fl_str_mv 2017-06-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/63817
Gallivanone, Francesca; Valente, Mauro Andres; Savi, Annarita; Canevari, Carla; Castiglioni, Isabella; Targeted radionuclide therapy: frontiers in theranostics; Landmark; Frontiers in bioscience (Landmark edition); 22; 1-6-2017; 1750-1759
1093-4715
CONICET Digital
CONICET
url http://hdl.handle.net/11336/63817
identifier_str_mv Gallivanone, Francesca; Valente, Mauro Andres; Savi, Annarita; Canevari, Carla; Castiglioni, Isabella; Targeted radionuclide therapy: frontiers in theranostics; Landmark; Frontiers in bioscience (Landmark edition); 22; 1-6-2017; 1750-1759
1093-4715
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.2741/4569
info:eu-repo/semantics/altIdentifier/url/https://www.bioscience.org/2017/v22/af/4569/list.htm
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Landmark
publisher.none.fl_str_mv Landmark
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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