Excitation-emission fluorescence spectroscopic analysis in the presence of interferents: A laboratory experiment integrating analytical chemistry and advanced data processing

Autores
Boeris, Valeria; Cabezon, Miguel Angel; Olivieri, Alejandro Cesar
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In the present report an advanced experiment is described to introduce chemistry students to the direct chemometric resolution of binary mixtures of two pharmaceuticals (oxatomide and phenylephrine) by measuring excitation-emission fluorescence matrices, and processing them with second-order calibration based on a decomposition algorithm called parallel factor analysis (PARAFAC). This experiment is of interest because it combines experimental analytical chemistry (preparation of standard solutions, spectrofluorimetric measurements, etc.) with computer applications not requiring deep programming skills. Second-order multivariate calibration was implemented with a simple graphical toolbox especially designed for this report: mvc2basic, which is available as supplementary material. This work provides students the opportunity to be introduced to advanced chemometrics activities in an accessible manner.
Fil: Boeris, Valeria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Instituto de Química Rosario; Argentina
Fil: Cabezon, Miguel Angel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Instituto de Química Rosario; Argentina
Fil: Olivieri, Alejandro Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Instituto de Química Rosario; Argentina
Materia
Laboratories And Demonstrations
Analytical Chemistry
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/3077
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/3077
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Excitation-emission fluorescence spectroscopic analysis in the presence of interferents: A laboratory experiment integrating analytical chemistry and advanced data processingBoeris, ValeriaCabezon, Miguel AngelOlivieri, Alejandro CesarLaboratories And DemonstrationsAnalytical Chemistryhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1In the present report an advanced experiment is described to introduce chemistry students to the direct chemometric resolution of binary mixtures of two pharmaceuticals (oxatomide and phenylephrine) by measuring excitation-emission fluorescence matrices, and processing them with second-order calibration based on a decomposition algorithm called parallel factor analysis (PARAFAC). This experiment is of interest because it combines experimental analytical chemistry (preparation of standard solutions, spectrofluorimetric measurements, etc.) with computer applications not requiring deep programming skills. Second-order multivariate calibration was implemented with a simple graphical toolbox especially designed for this report: mvc2basic, which is available as supplementary material. This work provides students the opportunity to be introduced to advanced chemometrics activities in an accessible manner.Fil: Boeris, Valeria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Instituto de Química Rosario; ArgentinaFil: Cabezon, Miguel Angel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Instituto de Química Rosario; ArgentinaFil: Olivieri, Alejandro Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Instituto de Química Rosario; ArgentinaThe Chemical Educator2013-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/3077Boeris, Valeria; Cabezon, Miguel Angel; Olivieri, Alejandro Cesar; Excitation-emission fluorescence spectroscopic analysis in the presence of interferents: A laboratory experiment integrating analytical chemistry and advanced data processing; The Chemical Educator; The Chemical Educator; 18; 5-2013; 165-1721430-4171enginfo:eu-repo/semantics/altIdentifier/url/http://chemeducator.org/bibs/0018001/18130165.htmlinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:26:26Zoai:ri.conicet.gov.ar:11336/3077instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:26:26.846CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Excitation-emission fluorescence spectroscopic analysis in the presence of interferents: A laboratory experiment integrating analytical chemistry and advanced data processing
title Excitation-emission fluorescence spectroscopic analysis in the presence of interferents: A laboratory experiment integrating analytical chemistry and advanced data processing
spellingShingle Excitation-emission fluorescence spectroscopic analysis in the presence of interferents: A laboratory experiment integrating analytical chemistry and advanced data processing
Boeris, Valeria
Laboratories And Demonstrations
Analytical Chemistry
title_short Excitation-emission fluorescence spectroscopic analysis in the presence of interferents: A laboratory experiment integrating analytical chemistry and advanced data processing
title_full Excitation-emission fluorescence spectroscopic analysis in the presence of interferents: A laboratory experiment integrating analytical chemistry and advanced data processing
title_fullStr Excitation-emission fluorescence spectroscopic analysis in the presence of interferents: A laboratory experiment integrating analytical chemistry and advanced data processing
title_full_unstemmed Excitation-emission fluorescence spectroscopic analysis in the presence of interferents: A laboratory experiment integrating analytical chemistry and advanced data processing
title_sort Excitation-emission fluorescence spectroscopic analysis in the presence of interferents: A laboratory experiment integrating analytical chemistry and advanced data processing
dc.creator.none.fl_str_mv Boeris, Valeria
Cabezon, Miguel Angel
Olivieri, Alejandro Cesar
author Boeris, Valeria
author_facet Boeris, Valeria
Cabezon, Miguel Angel
Olivieri, Alejandro Cesar
author_role author
author2 Cabezon, Miguel Angel
Olivieri, Alejandro Cesar
author2_role author
author
dc.subject.none.fl_str_mv Laboratories And Demonstrations
Analytical Chemistry
topic Laboratories And Demonstrations
Analytical Chemistry
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv In the present report an advanced experiment is described to introduce chemistry students to the direct chemometric resolution of binary mixtures of two pharmaceuticals (oxatomide and phenylephrine) by measuring excitation-emission fluorescence matrices, and processing them with second-order calibration based on a decomposition algorithm called parallel factor analysis (PARAFAC). This experiment is of interest because it combines experimental analytical chemistry (preparation of standard solutions, spectrofluorimetric measurements, etc.) with computer applications not requiring deep programming skills. Second-order multivariate calibration was implemented with a simple graphical toolbox especially designed for this report: mvc2basic, which is available as supplementary material. This work provides students the opportunity to be introduced to advanced chemometrics activities in an accessible manner.
Fil: Boeris, Valeria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Instituto de Química Rosario; Argentina
Fil: Cabezon, Miguel Angel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Instituto de Química Rosario; Argentina
Fil: Olivieri, Alejandro Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Instituto de Química Rosario; Argentina
description In the present report an advanced experiment is described to introduce chemistry students to the direct chemometric resolution of binary mixtures of two pharmaceuticals (oxatomide and phenylephrine) by measuring excitation-emission fluorescence matrices, and processing them with second-order calibration based on a decomposition algorithm called parallel factor analysis (PARAFAC). This experiment is of interest because it combines experimental analytical chemistry (preparation of standard solutions, spectrofluorimetric measurements, etc.) with computer applications not requiring deep programming skills. Second-order multivariate calibration was implemented with a simple graphical toolbox especially designed for this report: mvc2basic, which is available as supplementary material. This work provides students the opportunity to be introduced to advanced chemometrics activities in an accessible manner.
publishDate 2013
dc.date.none.fl_str_mv 2013-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/3077
Boeris, Valeria; Cabezon, Miguel Angel; Olivieri, Alejandro Cesar; Excitation-emission fluorescence spectroscopic analysis in the presence of interferents: A laboratory experiment integrating analytical chemistry and advanced data processing; The Chemical Educator; The Chemical Educator; 18; 5-2013; 165-172
1430-4171
url http://hdl.handle.net/11336/3077
identifier_str_mv Boeris, Valeria; Cabezon, Miguel Angel; Olivieri, Alejandro Cesar; Excitation-emission fluorescence spectroscopic analysis in the presence of interferents: A laboratory experiment integrating analytical chemistry and advanced data processing; The Chemical Educator; The Chemical Educator; 18; 5-2013; 165-172
1430-4171
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://chemeducator.org/bibs/0018001/18130165.html
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv The Chemical Educator
publisher.none.fl_str_mv The Chemical Educator
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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