Oral cavity and extra-oral plasmablastic lymphomas in AIDS patients: Report of five cases and review of the literature

Autores
Corti, Marcelo; Villafañe, M. F.; Bistmans, A.; Campitelli, A.; Narbaitz, M.; Baré, Patricia
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Plasmablastic lymphoma (PBL) is a distinct disease entity of the diffuse large B-cell lymphoma, which often occurs in HIV-positive patients. The immunophenotype of this lymphoid neoplasm is characterized by the presence of plasma cell-associated markers VS38c and CD138 antigens and the absence of B-cell markers such as CD20 and CD45. The most frequent site of involvement is the oral cavity and the jaw, while several reports describe the development of PBL in extra-oral sites including the lymph nodes, the anal canal, the soft tissue, the skin and the gastrointestinal tract as less frequent. Epstein Barr virus is often associated with PBL pathogenesis and the neoplastic cells contain this virus genome. Here we review the epidemiological, clinical, immunological, histopathological and virological characteristics and their prognosis and outcome in a series of five patients with diagnoses of HIV/AIDS and PBL.
Fil: Corti, Marcelo. Gobierno de la Ciudad de Buenos Aires. Hospital de Infecciosas "Dr. Francisco Javier Muñiz"; Argentina
Fil: Villafañe, M. F.. Gobierno de la Ciudad de Buenos Aires. Hospital de Infecciosas "Dr. Francisco Javier Muñiz"; Argentina
Fil: Bistmans, A.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina
Fil: Campitelli, A.. Gobierno de la Ciudad de Buenos Aires. Hospital de Infecciosas "Dr. Francisco Javier Muñiz"; Argentina
Fil: Narbaitz, M.. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas "Mariano R. Castex"; Argentina
Fil: Baré, Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas "Mariano R. Castex"; Argentina
Materia
AIDS
B-CELL LYMPHOMA
DLBCL
EPSTEIN-BARR VIRUS
HERPES VIRUS TYPE-8
HIV
PLASMABLASTIC LYMPHOMA
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/91426
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/91426
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Oral cavity and extra-oral plasmablastic lymphomas in AIDS patients: Report of five cases and review of the literatureCorti, MarceloVillafañe, M. F.Bistmans, A.Campitelli, A.Narbaitz, M.Baré, PatriciaAIDSB-CELL LYMPHOMADLBCLEPSTEIN-BARR VIRUSHERPES VIRUS TYPE-8HIVPLASMABLASTIC LYMPHOMAhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Plasmablastic lymphoma (PBL) is a distinct disease entity of the diffuse large B-cell lymphoma, which often occurs in HIV-positive patients. The immunophenotype of this lymphoid neoplasm is characterized by the presence of plasma cell-associated markers VS38c and CD138 antigens and the absence of B-cell markers such as CD20 and CD45. The most frequent site of involvement is the oral cavity and the jaw, while several reports describe the development of PBL in extra-oral sites including the lymph nodes, the anal canal, the soft tissue, the skin and the gastrointestinal tract as less frequent. Epstein Barr virus is often associated with PBL pathogenesis and the neoplastic cells contain this virus genome. Here we review the epidemiological, clinical, immunological, histopathological and virological characteristics and their prognosis and outcome in a series of five patients with diagnoses of HIV/AIDS and PBL.Fil: Corti, Marcelo. Gobierno de la Ciudad de Buenos Aires. Hospital de Infecciosas "Dr. Francisco Javier Muñiz"; ArgentinaFil: Villafañe, M. F.. Gobierno de la Ciudad de Buenos Aires. Hospital de Infecciosas "Dr. Francisco Javier Muñiz"; ArgentinaFil: Bistmans, A.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; ArgentinaFil: Campitelli, A.. Gobierno de la Ciudad de Buenos Aires. Hospital de Infecciosas "Dr. Francisco Javier Muñiz"; ArgentinaFil: Narbaitz, M.. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas "Mariano R. Castex"; ArgentinaFil: Baré, Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas "Mariano R. Castex"; ArgentinaRoyal Soc Medicine Press Ltd2011-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/91426Corti, Marcelo; Villafañe, M. F.; Bistmans, A.; Campitelli, A.; Narbaitz, M.; et al.; Oral cavity and extra-oral plasmablastic lymphomas in AIDS patients: Report of five cases and review of the literature; Royal Soc Medicine Press Ltd; International Journal Of Std & Aids.; 22; 12; 12-2011; 759-7630956-4624CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://journals.sagepub.com/doi/abs/10.1258/ijsa.2011.011235?journalCode=stdainfo:eu-repo/semantics/altIdentifier/doi/10.1258/ijsa.2011.011235info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T12:19:07Zoai:ri.conicet.gov.ar:11336/91426instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 12:19:07.786CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Oral cavity and extra-oral plasmablastic lymphomas in AIDS patients: Report of five cases and review of the literature
title Oral cavity and extra-oral plasmablastic lymphomas in AIDS patients: Report of five cases and review of the literature
spellingShingle Oral cavity and extra-oral plasmablastic lymphomas in AIDS patients: Report of five cases and review of the literature
Corti, Marcelo
AIDS
B-CELL LYMPHOMA
DLBCL
EPSTEIN-BARR VIRUS
HERPES VIRUS TYPE-8
HIV
PLASMABLASTIC LYMPHOMA
title_short Oral cavity and extra-oral plasmablastic lymphomas in AIDS patients: Report of five cases and review of the literature
title_full Oral cavity and extra-oral plasmablastic lymphomas in AIDS patients: Report of five cases and review of the literature
title_fullStr Oral cavity and extra-oral plasmablastic lymphomas in AIDS patients: Report of five cases and review of the literature
title_full_unstemmed Oral cavity and extra-oral plasmablastic lymphomas in AIDS patients: Report of five cases and review of the literature
title_sort Oral cavity and extra-oral plasmablastic lymphomas in AIDS patients: Report of five cases and review of the literature
dc.creator.none.fl_str_mv Corti, Marcelo
Villafañe, M. F.
Bistmans, A.
Campitelli, A.
Narbaitz, M.
Baré, Patricia
author Corti, Marcelo
author_facet Corti, Marcelo
Villafañe, M. F.
Bistmans, A.
Campitelli, A.
Narbaitz, M.
Baré, Patricia
author_role author
author2 Villafañe, M. F.
Bistmans, A.
Campitelli, A.
Narbaitz, M.
Baré, Patricia
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv AIDS
B-CELL LYMPHOMA
DLBCL
EPSTEIN-BARR VIRUS
HERPES VIRUS TYPE-8
HIV
PLASMABLASTIC LYMPHOMA
topic AIDS
B-CELL LYMPHOMA
DLBCL
EPSTEIN-BARR VIRUS
HERPES VIRUS TYPE-8
HIV
PLASMABLASTIC LYMPHOMA
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Plasmablastic lymphoma (PBL) is a distinct disease entity of the diffuse large B-cell lymphoma, which often occurs in HIV-positive patients. The immunophenotype of this lymphoid neoplasm is characterized by the presence of plasma cell-associated markers VS38c and CD138 antigens and the absence of B-cell markers such as CD20 and CD45. The most frequent site of involvement is the oral cavity and the jaw, while several reports describe the development of PBL in extra-oral sites including the lymph nodes, the anal canal, the soft tissue, the skin and the gastrointestinal tract as less frequent. Epstein Barr virus is often associated with PBL pathogenesis and the neoplastic cells contain this virus genome. Here we review the epidemiological, clinical, immunological, histopathological and virological characteristics and their prognosis and outcome in a series of five patients with diagnoses of HIV/AIDS and PBL.
Fil: Corti, Marcelo. Gobierno de la Ciudad de Buenos Aires. Hospital de Infecciosas "Dr. Francisco Javier Muñiz"; Argentina
Fil: Villafañe, M. F.. Gobierno de la Ciudad de Buenos Aires. Hospital de Infecciosas "Dr. Francisco Javier Muñiz"; Argentina
Fil: Bistmans, A.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Ramos Mejía"; Argentina
Fil: Campitelli, A.. Gobierno de la Ciudad de Buenos Aires. Hospital de Infecciosas "Dr. Francisco Javier Muñiz"; Argentina
Fil: Narbaitz, M.. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas "Mariano R. Castex"; Argentina
Fil: Baré, Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas "Mariano R. Castex"; Argentina
description Plasmablastic lymphoma (PBL) is a distinct disease entity of the diffuse large B-cell lymphoma, which often occurs in HIV-positive patients. The immunophenotype of this lymphoid neoplasm is characterized by the presence of plasma cell-associated markers VS38c and CD138 antigens and the absence of B-cell markers such as CD20 and CD45. The most frequent site of involvement is the oral cavity and the jaw, while several reports describe the development of PBL in extra-oral sites including the lymph nodes, the anal canal, the soft tissue, the skin and the gastrointestinal tract as less frequent. Epstein Barr virus is often associated with PBL pathogenesis and the neoplastic cells contain this virus genome. Here we review the epidemiological, clinical, immunological, histopathological and virological characteristics and their prognosis and outcome in a series of five patients with diagnoses of HIV/AIDS and PBL.
publishDate 2011
dc.date.none.fl_str_mv 2011-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/91426
Corti, Marcelo; Villafañe, M. F.; Bistmans, A.; Campitelli, A.; Narbaitz, M.; et al.; Oral cavity and extra-oral plasmablastic lymphomas in AIDS patients: Report of five cases and review of the literature; Royal Soc Medicine Press Ltd; International Journal Of Std & Aids.; 22; 12; 12-2011; 759-763
0956-4624
CONICET Digital
CONICET
url http://hdl.handle.net/11336/91426
identifier_str_mv Corti, Marcelo; Villafañe, M. F.; Bistmans, A.; Campitelli, A.; Narbaitz, M.; et al.; Oral cavity and extra-oral plasmablastic lymphomas in AIDS patients: Report of five cases and review of the literature; Royal Soc Medicine Press Ltd; International Journal Of Std & Aids.; 22; 12; 12-2011; 759-763
0956-4624
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://journals.sagepub.com/doi/abs/10.1258/ijsa.2011.011235?journalCode=stda
info:eu-repo/semantics/altIdentifier/doi/10.1258/ijsa.2011.011235
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Royal Soc Medicine Press Ltd
publisher.none.fl_str_mv Royal Soc Medicine Press Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846782627806183424
score 12.982451

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