Sulfurated and oxygenated imidazoline derivatives: Synthesis, antioxidant activity and light‐mediated antibacterial activity

Autores
Faillace, Martín Sebastián; Silva, Ana Paula; Alves Borges Leal, Antonio Linkoln; Muratori da Costa, Luciana; Barreto, Humberto Medeiros; Peláez, Walter José
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Imidazoline derivatives with different exocyclic substituents were simply prepared from common starting materials. The procedures were carried out in an eco-friendly manner. The antioxidant activity of these derivatives was explored by different experimental assays, such as ABTS.+ and DPPH. scavenging assay, as well as reducing power assay. The structural differences are discussed in terms of the results. Sulfur analogs showed higher antioxidant activity than their oxygenated counterparts. The same tendency was observed in microbiological studies, in which the same imidazoline compounds were assayed for light-mediated activity against of Staphylococcus aureus and Escherichia coli strains. A light-enhanced activity was observed for almost all the sulfated imidazolines after exposure to UV-A (400-320 nm) light.
Fil: Faillace, Martín Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Silva, Ana Paula. Universidade Federal do Piaui; Brasil
Fil: Alves Borges Leal, Antonio Linkoln. Universidade Federal do Piaui; Brasil
Fil: Muratori da Costa, Luciana. Universidade Federal do Piaui; Brasil
Fil: Barreto, Humberto Medeiros. Universidade Federal do Piaui; Brasil
Fil: Peláez, Walter José. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Materia
ANTIBIOTIC RESISTANCE
ANTIOXIDANTS
IMIDAZOLINE
MICROWAVE CHEMISTRY
S. AUREUS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/144336
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Sulfurated and oxygenated imidazoline derivatives: Synthesis, antioxidant activity and light‐mediated antibacterial activityFaillace, Martín SebastiánSilva, Ana PaulaAlves Borges Leal, Antonio LinkolnMuratori da Costa, LucianaBarreto, Humberto MedeirosPeláez, Walter JoséANTIBIOTIC RESISTANCEANTIOXIDANTSIMIDAZOLINEMICROWAVE CHEMISTRYS. AUREUShttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Imidazoline derivatives with different exocyclic substituents were simply prepared from common starting materials. The procedures were carried out in an eco-friendly manner. The antioxidant activity of these derivatives was explored by different experimental assays, such as ABTS.+ and DPPH. scavenging assay, as well as reducing power assay. The structural differences are discussed in terms of the results. Sulfur analogs showed higher antioxidant activity than their oxygenated counterparts. The same tendency was observed in microbiological studies, in which the same imidazoline compounds were assayed for light-mediated activity against of Staphylococcus aureus and Escherichia coli strains. A light-enhanced activity was observed for almost all the sulfated imidazolines after exposure to UV-A (400-320 nm) light.Fil: Faillace, Martín Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaFil: Silva, Ana Paula. Universidade Federal do Piaui; BrasilFil: Alves Borges Leal, Antonio Linkoln. Universidade Federal do Piaui; BrasilFil: Muratori da Costa, Luciana. Universidade Federal do Piaui; BrasilFil: Barreto, Humberto Medeiros. Universidade Federal do Piaui; BrasilFil: Peláez, Walter José. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaWiley VCH Verlag2020-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/144336Faillace, Martín Sebastián; Silva, Ana Paula; Alves Borges Leal, Antonio Linkoln; Muratori da Costa, Luciana; Barreto, Humberto Medeiros; et al.; Sulfurated and oxygenated imidazoline derivatives: Synthesis, antioxidant activity and light‐mediated antibacterial activity; Wiley VCH Verlag; Chemmedchem; 15; 10; 3-2020; 851-8611860-71791860-7187CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1002/cmdc.202000048info:eu-repo/semantics/altIdentifier/doi/10.1002/cmdc.202000048info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:03:27Zoai:ri.conicet.gov.ar:11336/144336instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:03:28.018CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Sulfurated and oxygenated imidazoline derivatives: Synthesis, antioxidant activity and light‐mediated antibacterial activity
title Sulfurated and oxygenated imidazoline derivatives: Synthesis, antioxidant activity and light‐mediated antibacterial activity
spellingShingle Sulfurated and oxygenated imidazoline derivatives: Synthesis, antioxidant activity and light‐mediated antibacterial activity
Faillace, Martín Sebastián
ANTIBIOTIC RESISTANCE
ANTIOXIDANTS
IMIDAZOLINE
MICROWAVE CHEMISTRY
S. AUREUS
title_short Sulfurated and oxygenated imidazoline derivatives: Synthesis, antioxidant activity and light‐mediated antibacterial activity
title_full Sulfurated and oxygenated imidazoline derivatives: Synthesis, antioxidant activity and light‐mediated antibacterial activity
title_fullStr Sulfurated and oxygenated imidazoline derivatives: Synthesis, antioxidant activity and light‐mediated antibacterial activity
title_full_unstemmed Sulfurated and oxygenated imidazoline derivatives: Synthesis, antioxidant activity and light‐mediated antibacterial activity
title_sort Sulfurated and oxygenated imidazoline derivatives: Synthesis, antioxidant activity and light‐mediated antibacterial activity
dc.creator.none.fl_str_mv Faillace, Martín Sebastián
Silva, Ana Paula
Alves Borges Leal, Antonio Linkoln
Muratori da Costa, Luciana
Barreto, Humberto Medeiros
Peláez, Walter José
author Faillace, Martín Sebastián
author_facet Faillace, Martín Sebastián
Silva, Ana Paula
Alves Borges Leal, Antonio Linkoln
Muratori da Costa, Luciana
Barreto, Humberto Medeiros
Peláez, Walter José
author_role author
author2 Silva, Ana Paula
Alves Borges Leal, Antonio Linkoln
Muratori da Costa, Luciana
Barreto, Humberto Medeiros
Peláez, Walter José
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv ANTIBIOTIC RESISTANCE
ANTIOXIDANTS
IMIDAZOLINE
MICROWAVE CHEMISTRY
S. AUREUS
topic ANTIBIOTIC RESISTANCE
ANTIOXIDANTS
IMIDAZOLINE
MICROWAVE CHEMISTRY
S. AUREUS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Imidazoline derivatives with different exocyclic substituents were simply prepared from common starting materials. The procedures were carried out in an eco-friendly manner. The antioxidant activity of these derivatives was explored by different experimental assays, such as ABTS.+ and DPPH. scavenging assay, as well as reducing power assay. The structural differences are discussed in terms of the results. Sulfur analogs showed higher antioxidant activity than their oxygenated counterparts. The same tendency was observed in microbiological studies, in which the same imidazoline compounds were assayed for light-mediated activity against of Staphylococcus aureus and Escherichia coli strains. A light-enhanced activity was observed for almost all the sulfated imidazolines after exposure to UV-A (400-320 nm) light.
Fil: Faillace, Martín Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Silva, Ana Paula. Universidade Federal do Piaui; Brasil
Fil: Alves Borges Leal, Antonio Linkoln. Universidade Federal do Piaui; Brasil
Fil: Muratori da Costa, Luciana. Universidade Federal do Piaui; Brasil
Fil: Barreto, Humberto Medeiros. Universidade Federal do Piaui; Brasil
Fil: Peláez, Walter José. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
description Imidazoline derivatives with different exocyclic substituents were simply prepared from common starting materials. The procedures were carried out in an eco-friendly manner. The antioxidant activity of these derivatives was explored by different experimental assays, such as ABTS.+ and DPPH. scavenging assay, as well as reducing power assay. The structural differences are discussed in terms of the results. Sulfur analogs showed higher antioxidant activity than their oxygenated counterparts. The same tendency was observed in microbiological studies, in which the same imidazoline compounds were assayed for light-mediated activity against of Staphylococcus aureus and Escherichia coli strains. A light-enhanced activity was observed for almost all the sulfated imidazolines after exposure to UV-A (400-320 nm) light.
publishDate 2020
dc.date.none.fl_str_mv 2020-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/144336
Faillace, Martín Sebastián; Silva, Ana Paula; Alves Borges Leal, Antonio Linkoln; Muratori da Costa, Luciana; Barreto, Humberto Medeiros; et al.; Sulfurated and oxygenated imidazoline derivatives: Synthesis, antioxidant activity and light‐mediated antibacterial activity; Wiley VCH Verlag; Chemmedchem; 15; 10; 3-2020; 851-861
1860-7179
1860-7187
CONICET Digital
CONICET
url http://hdl.handle.net/11336/144336
identifier_str_mv Faillace, Martín Sebastián; Silva, Ana Paula; Alves Borges Leal, Antonio Linkoln; Muratori da Costa, Luciana; Barreto, Humberto Medeiros; et al.; Sulfurated and oxygenated imidazoline derivatives: Synthesis, antioxidant activity and light‐mediated antibacterial activity; Wiley VCH Verlag; Chemmedchem; 15; 10; 3-2020; 851-861
1860-7179
1860-7187
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1002/cmdc.202000048
info:eu-repo/semantics/altIdentifier/doi/10.1002/cmdc.202000048
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley VCH Verlag
publisher.none.fl_str_mv Wiley VCH Verlag
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846781267927891968
score 12.982451

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