Dengue beyond the tropics: a time-series study comprising 2015-2016 versus 2019-2020 at a children’s hospital in the City of Buenos Aires
- Autores
- Berberian, Griselda Virginia; Perez, Guadalupe; Mangano, Andrea María Mercedes; Borgnia, Daniela; Buchovsky, Ana Sabrina; Costa, Marina; Fabri, Cintia; Luppo, Victoria Celina; Mitchenko, Alicia S.; Deschutter, Verónica; Botana, Claudia; Martiren, Soledad; Brizuela, Martin Eduardo; Arias, Ana P.; Rosanova, María T.
- Año de publicación
- 2022
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Introduction: Dengue is a public health problem worldwide. It was originally confined to tropical and subtropical areas, but it is now present in other regions, such as Argentina. Epidemic outbreaks have been observed in the City of Buenos Aires since 2008, with few reports in children.Objective: To analyze and compare the clinical, epidemiological, laboratory, and evolutionary characteristics of the latest 2 dengue outbreaks outside the endemic area.Population and methods: Time-series study. Patients under 18 years of age with probable or confirmed dengue and evaluated in a children´s hospital of the City of Buenos Aires during the periods 2015-2016 and 2019-2020 were included.Results: A total of 239 patients were included; 29 (12%) had a history of travel. Their median age was 132 months (interquartile range: 102- 156). All had a fever. Other symptoms included headache in 170 (71%), myalgia in 129 (54%), and rash in 122 (51%). Forty patients (17%) had comorbidities. Warning signs were observed in 79 patients (33%); 14 (6%) developed severe dengue; 115 (45%) were hospitalized; none died. DENV-1 was the most common serotype. A history of travel and hospitalization prevailed in the first period; severe dengue and prior infection, in the second period.Conclusions: No patient died due to dengue in either study period. Statistically significant differences were observed in the frequency of hospitalization; a history of travel was more common in the 2015-2016 period and severe dengue, in the 2019-2020 period.
Fil: Berberian, Griselda Virginia. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Perez, Guadalupe. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Mangano, Andrea María Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Borgnia, Daniela. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Buchovsky, Ana Sabrina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Costa, Marina. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Fabri, Cintia. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Luppo, Victoria Celina. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán"; Argentina
Fil: Mitchenko, Alicia S.. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán"; Argentina
Fil: Deschutter, Verónica. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Botana, Claudia. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán"; Argentina
Fil: Martiren, Soledad. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Brizuela, Martin Eduardo. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Arias, Ana P.. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Rosanova, María T.. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina - Materia
-
CHILD
DENGUE
MOSQUITO-BORNE DISEASES - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
.jpg)
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/246656
Ver los metadatos del registro completo
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Dengue beyond the tropics: a time-series study comprising 2015-2016 versus 2019-2020 at a children’s hospital in the City of Buenos AiresBerberian, Griselda VirginiaPerez, GuadalupeMangano, Andrea María MercedesBorgnia, DanielaBuchovsky, Ana SabrinaCosta, MarinaFabri, CintiaLuppo, Victoria CelinaMitchenko, Alicia S.Deschutter, VerónicaBotana, ClaudiaMartiren, SoledadBrizuela, Martin EduardoArias, Ana P.Rosanova, María T.CHILDDENGUEMOSQUITO-BORNE DISEASEShttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Introduction: Dengue is a public health problem worldwide. It was originally confined to tropical and subtropical areas, but it is now present in other regions, such as Argentina. Epidemic outbreaks have been observed in the City of Buenos Aires since 2008, with few reports in children.Objective: To analyze and compare the clinical, epidemiological, laboratory, and evolutionary characteristics of the latest 2 dengue outbreaks outside the endemic area.Population and methods: Time-series study. Patients under 18 years of age with probable or confirmed dengue and evaluated in a children´s hospital of the City of Buenos Aires during the periods 2015-2016 and 2019-2020 were included.Results: A total of 239 patients were included; 29 (12%) had a history of travel. Their median age was 132 months (interquartile range: 102- 156). All had a fever. Other symptoms included headache in 170 (71%), myalgia in 129 (54%), and rash in 122 (51%). Forty patients (17%) had comorbidities. Warning signs were observed in 79 patients (33%); 14 (6%) developed severe dengue; 115 (45%) were hospitalized; none died. DENV-1 was the most common serotype. A history of travel and hospitalization prevailed in the first period; severe dengue and prior infection, in the second period.Conclusions: No patient died due to dengue in either study period. Statistically significant differences were observed in the frequency of hospitalization; a history of travel was more common in the 2015-2016 period and severe dengue, in the 2019-2020 period.Fil: Berberian, Griselda Virginia. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Perez, Guadalupe. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Mangano, Andrea María Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Borgnia, Daniela. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Buchovsky, Ana Sabrina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Costa, Marina. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Fabri, Cintia. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Luppo, Victoria Celina. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán"; ArgentinaFil: Mitchenko, Alicia S.. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán"; ArgentinaFil: Deschutter, Verónica. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Botana, Claudia. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán"; ArgentinaFil: Martiren, Soledad. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Brizuela, Martin Eduardo. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Arias, Ana P.. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Rosanova, María T.. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaSociedad Argentina de Pediatría2022-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/246656Berberian, Griselda Virginia; Perez, Guadalupe; Mangano, Andrea María Mercedes; Borgnia, Daniela; Buchovsky, Ana Sabrina; et al.; Dengue beyond the tropics: a time-series study comprising 2015-2016 versus 2019-2020 at a children’s hospital in the City of Buenos Aires; Sociedad Argentina de Pediatría; Archivos Argentinos de Pediatría; 120; 6; 12-2022; 384-3900325-00751668-3501CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sap.org.ar/docs/publicaciones/archivosarg/2022/v120n6a06e.pdfinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:23:05Zoai:ri.conicet.gov.ar:11336/246656instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:23:05.954CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
| dc.title.none.fl_str_mv |
Dengue beyond the tropics: a time-series study comprising 2015-2016 versus 2019-2020 at a children’s hospital in the City of Buenos Aires |
| title |
Dengue beyond the tropics: a time-series study comprising 2015-2016 versus 2019-2020 at a children’s hospital in the City of Buenos Aires |
| spellingShingle |
Dengue beyond the tropics: a time-series study comprising 2015-2016 versus 2019-2020 at a children’s hospital in the City of Buenos Aires Berberian, Griselda Virginia CHILD DENGUE MOSQUITO-BORNE DISEASES |
| title_short |
Dengue beyond the tropics: a time-series study comprising 2015-2016 versus 2019-2020 at a children’s hospital in the City of Buenos Aires |
| title_full |
Dengue beyond the tropics: a time-series study comprising 2015-2016 versus 2019-2020 at a children’s hospital in the City of Buenos Aires |
| title_fullStr |
Dengue beyond the tropics: a time-series study comprising 2015-2016 versus 2019-2020 at a children’s hospital in the City of Buenos Aires |
| title_full_unstemmed |
Dengue beyond the tropics: a time-series study comprising 2015-2016 versus 2019-2020 at a children’s hospital in the City of Buenos Aires |
| title_sort |
Dengue beyond the tropics: a time-series study comprising 2015-2016 versus 2019-2020 at a children’s hospital in the City of Buenos Aires |
| dc.creator.none.fl_str_mv |
Berberian, Griselda Virginia Perez, Guadalupe Mangano, Andrea María Mercedes Borgnia, Daniela Buchovsky, Ana Sabrina Costa, Marina Fabri, Cintia Luppo, Victoria Celina Mitchenko, Alicia S. Deschutter, Verónica Botana, Claudia Martiren, Soledad Brizuela, Martin Eduardo Arias, Ana P. Rosanova, María T. |
| author |
Berberian, Griselda Virginia |
| author_facet |
Berberian, Griselda Virginia Perez, Guadalupe Mangano, Andrea María Mercedes Borgnia, Daniela Buchovsky, Ana Sabrina Costa, Marina Fabri, Cintia Luppo, Victoria Celina Mitchenko, Alicia S. Deschutter, Verónica Botana, Claudia Martiren, Soledad Brizuela, Martin Eduardo Arias, Ana P. Rosanova, María T. |
| author_role |
author |
| author2 |
Perez, Guadalupe Mangano, Andrea María Mercedes Borgnia, Daniela Buchovsky, Ana Sabrina Costa, Marina Fabri, Cintia Luppo, Victoria Celina Mitchenko, Alicia S. Deschutter, Verónica Botana, Claudia Martiren, Soledad Brizuela, Martin Eduardo Arias, Ana P. Rosanova, María T. |
| author2_role |
author author author author author author author author author author author author author author |
| dc.subject.none.fl_str_mv |
CHILD DENGUE MOSQUITO-BORNE DISEASES |
| topic |
CHILD DENGUE MOSQUITO-BORNE DISEASES |
| purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.3 https://purl.org/becyt/ford/3 |
| dc.description.none.fl_txt_mv |
Introduction: Dengue is a public health problem worldwide. It was originally confined to tropical and subtropical areas, but it is now present in other regions, such as Argentina. Epidemic outbreaks have been observed in the City of Buenos Aires since 2008, with few reports in children.Objective: To analyze and compare the clinical, epidemiological, laboratory, and evolutionary characteristics of the latest 2 dengue outbreaks outside the endemic area.Population and methods: Time-series study. Patients under 18 years of age with probable or confirmed dengue and evaluated in a children´s hospital of the City of Buenos Aires during the periods 2015-2016 and 2019-2020 were included.Results: A total of 239 patients were included; 29 (12%) had a history of travel. Their median age was 132 months (interquartile range: 102- 156). All had a fever. Other symptoms included headache in 170 (71%), myalgia in 129 (54%), and rash in 122 (51%). Forty patients (17%) had comorbidities. Warning signs were observed in 79 patients (33%); 14 (6%) developed severe dengue; 115 (45%) were hospitalized; none died. DENV-1 was the most common serotype. A history of travel and hospitalization prevailed in the first period; severe dengue and prior infection, in the second period.Conclusions: No patient died due to dengue in either study period. Statistically significant differences were observed in the frequency of hospitalization; a history of travel was more common in the 2015-2016 period and severe dengue, in the 2019-2020 period. Fil: Berberian, Griselda Virginia. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina Fil: Perez, Guadalupe. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina Fil: Mangano, Andrea María Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina Fil: Borgnia, Daniela. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina Fil: Buchovsky, Ana Sabrina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina Fil: Costa, Marina. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina Fil: Fabri, Cintia. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina Fil: Luppo, Victoria Celina. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán"; Argentina Fil: Mitchenko, Alicia S.. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán"; Argentina Fil: Deschutter, Verónica. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina Fil: Botana, Claudia. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán"; Argentina Fil: Martiren, Soledad. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina Fil: Brizuela, Martin Eduardo. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina Fil: Arias, Ana P.. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina Fil: Rosanova, María T.. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina |
| description |
Introduction: Dengue is a public health problem worldwide. It was originally confined to tropical and subtropical areas, but it is now present in other regions, such as Argentina. Epidemic outbreaks have been observed in the City of Buenos Aires since 2008, with few reports in children.Objective: To analyze and compare the clinical, epidemiological, laboratory, and evolutionary characteristics of the latest 2 dengue outbreaks outside the endemic area.Population and methods: Time-series study. Patients under 18 years of age with probable or confirmed dengue and evaluated in a children´s hospital of the City of Buenos Aires during the periods 2015-2016 and 2019-2020 were included.Results: A total of 239 patients were included; 29 (12%) had a history of travel. Their median age was 132 months (interquartile range: 102- 156). All had a fever. Other symptoms included headache in 170 (71%), myalgia in 129 (54%), and rash in 122 (51%). Forty patients (17%) had comorbidities. Warning signs were observed in 79 patients (33%); 14 (6%) developed severe dengue; 115 (45%) were hospitalized; none died. DENV-1 was the most common serotype. A history of travel and hospitalization prevailed in the first period; severe dengue and prior infection, in the second period.Conclusions: No patient died due to dengue in either study period. Statistically significant differences were observed in the frequency of hospitalization; a history of travel was more common in the 2015-2016 period and severe dengue, in the 2019-2020 period. |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-12 |
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info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
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article |
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publishedVersion |
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http://hdl.handle.net/11336/246656 Berberian, Griselda Virginia; Perez, Guadalupe; Mangano, Andrea María Mercedes; Borgnia, Daniela; Buchovsky, Ana Sabrina; et al.; Dengue beyond the tropics: a time-series study comprising 2015-2016 versus 2019-2020 at a children’s hospital in the City of Buenos Aires; Sociedad Argentina de Pediatría; Archivos Argentinos de Pediatría; 120; 6; 12-2022; 384-390 0325-0075 1668-3501 CONICET Digital CONICET |
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http://hdl.handle.net/11336/246656 |
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Berberian, Griselda Virginia; Perez, Guadalupe; Mangano, Andrea María Mercedes; Borgnia, Daniela; Buchovsky, Ana Sabrina; et al.; Dengue beyond the tropics: a time-series study comprising 2015-2016 versus 2019-2020 at a children’s hospital in the City of Buenos Aires; Sociedad Argentina de Pediatría; Archivos Argentinos de Pediatría; 120; 6; 12-2022; 384-390 0325-0075 1668-3501 CONICET Digital CONICET |
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eng |
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eng |
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info:eu-repo/semantics/altIdentifier/url/https://www.sap.org.ar/docs/publicaciones/archivosarg/2022/v120n6a06e.pdf |
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Sociedad Argentina de Pediatría |
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Sociedad Argentina de Pediatría |
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dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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