Emissions from Electronic Cigarettes: Assessing Vapers’ Intake of Toxic Compounds, Secondhand Exposures, and the Associated Health Impacts

Autores
Logue, Jennifer M.; Sleiman, Mohamad; Montesinos, Victor Nahuel; Russell, Marion L.; Litter, Marta Irene; Benowitz, Neal L.; Gundel, Lara A.; Destaillats, Hugo
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
E-cigarettes likely represent a lower risk to health than traditional combustion cigarettes, but they are not innocuous. Recently reported emission rates of potentially harmful compounds were used to assess intake and predict health impacts for vapers and bystanders exposed passively. Vapers' toxicant intake was calculated for scenarios in which different e-liquids were used with various vaporizers, battery power settings and vaping regimes. For a high rate of 250 puff day-1 using a typical vaping regime and popular tank devices with battery voltages from 3.8 to 4.8 V, users were predicted to inhale formaldehyde (up to 49 mg day-1), acrolein (up to 10 mg day-1) and diacetyl (up to 0.5 mg day-1), at levels that exceeded U.S. occupational limits. Formaldehyde intake from 100 daily puffs was higher than the amount inhaled by a smoker consuming 10 conventional cigarettes per day. Secondhand exposures were predicted for two typical indoor scenarios: a home and a bar. Contributions from vaping to air pollutant concentrations in the home did not exceed the California OEHHA 8-h reference exposure levels (RELs), except when a high emitting device was used at 4.8 V. In that extreme scenario, the contributions from vaping amounted to as much as 12 μg m-3 formaldehyde and 2.6 μg m-3 acrolein. Pollutant concentrations in bars were modeled using indoor volumes, air exchange rates and the number of hourly users reported in the literature for U.S. bars in which smoking was allowed. Predicted contributions to indoor air levels were higher than those in the residential scenario. Formaldehyde (on average 135 μg m-3) and acrolein (28 μg m-3) exceeded the acute 1-h exposure REL for the highest emitting vaporizer/voltage combination. Predictions for these compounds also exceeded the 8-h REL in several bars when less intense vaping conditions were considered. Benzene concentrations in a few bars approached the 8-h REL, and diacetyl levels were close to the lower limit for occupational exposures. The integrated health damage from passive vaping was derived by computing disability-adjusted life years (DALYs) lost due to exposure to secondhand vapor. Acrolein was the dominant contributor to the aggregate harm. DALYs for the various device/voltage combinations were lower than - or comparable to - those estimated for exposures to secondhand and thirdhand tobacco smoke.
Fil: Logue, Jennifer M.. Lawrence Berkeley National Laboratory. Environmental Energy Technologies División. Indoor Environment Group; Estados Unidos
Fil: Sleiman, Mohamad. Lawrence Berkeley National Laboratory. Environmental Energy Technologies División. Indoor Environment Group; Estados Unidos. Institut de Chimie de Clermont-ferrand; Francia
Fil: Montesinos, Victor Nahuel. Comisión Nacional de Energía Atómica. Gerencia del Área de Seguridad Nuclear y Ambiente. Gerencia de Química (CAC); Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Russell, Marion L.. Lawrence Berkeley National Laboratory. Environmental Energy Technologies División. Indoor Environment Group; Estados Unidos
Fil: Litter, Marta Irene. Universidad Nacional de San Martín. Instituto de Investigación en Ingeniería Ambiental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica. Gerencia del Área de Seguridad Nuclear y Ambiente. Gerencia de Química (CAC); Argentina
Fil: Benowitz, Neal L.. University Of San Francisco.; Estados Unidos
Fil: Gundel, Lara A.. Lawrence Berkeley National Laboratory. Environmental Energy Technologies División. Indoor Environment Group; Estados Unidos
Fil: Destaillats, Hugo. Lawrence Berkeley National Laboratory. Environmental Energy Technologies División. Indoor Environment Group; Estados Unidos
Materia
e-cigs
DALYs
Acrolein
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/117569

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spelling Emissions from Electronic Cigarettes: Assessing Vapers’ Intake of Toxic Compounds, Secondhand Exposures, and the Associated Health ImpactsLogue, Jennifer M.Sleiman, MohamadMontesinos, Victor NahuelRussell, Marion L.Litter, Marta IreneBenowitz, Neal L.Gundel, Lara A.Destaillats, Hugoe-cigsDALYsAcroleinhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1E-cigarettes likely represent a lower risk to health than traditional combustion cigarettes, but they are not innocuous. Recently reported emission rates of potentially harmful compounds were used to assess intake and predict health impacts for vapers and bystanders exposed passively. Vapers' toxicant intake was calculated for scenarios in which different e-liquids were used with various vaporizers, battery power settings and vaping regimes. For a high rate of 250 puff day-1 using a typical vaping regime and popular tank devices with battery voltages from 3.8 to 4.8 V, users were predicted to inhale formaldehyde (up to 49 mg day-1), acrolein (up to 10 mg day-1) and diacetyl (up to 0.5 mg day-1), at levels that exceeded U.S. occupational limits. Formaldehyde intake from 100 daily puffs was higher than the amount inhaled by a smoker consuming 10 conventional cigarettes per day. Secondhand exposures were predicted for two typical indoor scenarios: a home and a bar. Contributions from vaping to air pollutant concentrations in the home did not exceed the California OEHHA 8-h reference exposure levels (RELs), except when a high emitting device was used at 4.8 V. In that extreme scenario, the contributions from vaping amounted to as much as 12 μg m-3 formaldehyde and 2.6 μg m-3 acrolein. Pollutant concentrations in bars were modeled using indoor volumes, air exchange rates and the number of hourly users reported in the literature for U.S. bars in which smoking was allowed. Predicted contributions to indoor air levels were higher than those in the residential scenario. Formaldehyde (on average 135 μg m-3) and acrolein (28 μg m-3) exceeded the acute 1-h exposure REL for the highest emitting vaporizer/voltage combination. Predictions for these compounds also exceeded the 8-h REL in several bars when less intense vaping conditions were considered. Benzene concentrations in a few bars approached the 8-h REL, and diacetyl levels were close to the lower limit for occupational exposures. The integrated health damage from passive vaping was derived by computing disability-adjusted life years (DALYs) lost due to exposure to secondhand vapor. Acrolein was the dominant contributor to the aggregate harm. DALYs for the various device/voltage combinations were lower than - or comparable to - those estimated for exposures to secondhand and thirdhand tobacco smoke.Fil: Logue, Jennifer M.. Lawrence Berkeley National Laboratory. Environmental Energy Technologies División. Indoor Environment Group; Estados UnidosFil: Sleiman, Mohamad. Lawrence Berkeley National Laboratory. Environmental Energy Technologies División. Indoor Environment Group; Estados Unidos. Institut de Chimie de Clermont-ferrand; FranciaFil: Montesinos, Victor Nahuel. Comisión Nacional de Energía Atómica. Gerencia del Área de Seguridad Nuclear y Ambiente. Gerencia de Química (CAC); Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Russell, Marion L.. Lawrence Berkeley National Laboratory. Environmental Energy Technologies División. Indoor Environment Group; Estados UnidosFil: Litter, Marta Irene. Universidad Nacional de San Martín. Instituto de Investigación en Ingeniería Ambiental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica. Gerencia del Área de Seguridad Nuclear y Ambiente. Gerencia de Química (CAC); ArgentinaFil: Benowitz, Neal L.. University Of San Francisco.; Estados UnidosFil: Gundel, Lara A.. Lawrence Berkeley National Laboratory. Environmental Energy Technologies División. Indoor Environment Group; Estados UnidosFil: Destaillats, Hugo. Lawrence Berkeley National Laboratory. Environmental Energy Technologies División. Indoor Environment Group; Estados UnidosAmerican Chemical Society2017-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/117569Logue, Jennifer M.; Sleiman, Mohamad; Montesinos, Victor Nahuel; Russell, Marion L.; Litter, Marta Irene; et al.; Emissions from Electronic Cigarettes: Assessing Vapers’ Intake of Toxic Compounds, Secondhand Exposures, and the Associated Health Impacts; American Chemical Society; Environmental Science & Technology; 51; 16; 8-2017; 9271-92790013-936XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://pubs.acs.org/doi/abs/10.1021/acs.est.7b00710info:eu-repo/semantics/altIdentifier/doi/10.1021/acs.est.7b00710info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:39:15Zoai:ri.conicet.gov.ar:11336/117569instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:39:15.611CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Emissions from Electronic Cigarettes: Assessing Vapers’ Intake of Toxic Compounds, Secondhand Exposures, and the Associated Health Impacts
title Emissions from Electronic Cigarettes: Assessing Vapers’ Intake of Toxic Compounds, Secondhand Exposures, and the Associated Health Impacts
spellingShingle Emissions from Electronic Cigarettes: Assessing Vapers’ Intake of Toxic Compounds, Secondhand Exposures, and the Associated Health Impacts
Logue, Jennifer M.
e-cigs
DALYs
Acrolein
title_short Emissions from Electronic Cigarettes: Assessing Vapers’ Intake of Toxic Compounds, Secondhand Exposures, and the Associated Health Impacts
title_full Emissions from Electronic Cigarettes: Assessing Vapers’ Intake of Toxic Compounds, Secondhand Exposures, and the Associated Health Impacts
title_fullStr Emissions from Electronic Cigarettes: Assessing Vapers’ Intake of Toxic Compounds, Secondhand Exposures, and the Associated Health Impacts
title_full_unstemmed Emissions from Electronic Cigarettes: Assessing Vapers’ Intake of Toxic Compounds, Secondhand Exposures, and the Associated Health Impacts
title_sort Emissions from Electronic Cigarettes: Assessing Vapers’ Intake of Toxic Compounds, Secondhand Exposures, and the Associated Health Impacts
dc.creator.none.fl_str_mv Logue, Jennifer M.
Sleiman, Mohamad
Montesinos, Victor Nahuel
Russell, Marion L.
Litter, Marta Irene
Benowitz, Neal L.
Gundel, Lara A.
Destaillats, Hugo
author Logue, Jennifer M.
author_facet Logue, Jennifer M.
Sleiman, Mohamad
Montesinos, Victor Nahuel
Russell, Marion L.
Litter, Marta Irene
Benowitz, Neal L.
Gundel, Lara A.
Destaillats, Hugo
author_role author
author2 Sleiman, Mohamad
Montesinos, Victor Nahuel
Russell, Marion L.
Litter, Marta Irene
Benowitz, Neal L.
Gundel, Lara A.
Destaillats, Hugo
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv e-cigs
DALYs
Acrolein
topic e-cigs
DALYs
Acrolein
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv E-cigarettes likely represent a lower risk to health than traditional combustion cigarettes, but they are not innocuous. Recently reported emission rates of potentially harmful compounds were used to assess intake and predict health impacts for vapers and bystanders exposed passively. Vapers' toxicant intake was calculated for scenarios in which different e-liquids were used with various vaporizers, battery power settings and vaping regimes. For a high rate of 250 puff day-1 using a typical vaping regime and popular tank devices with battery voltages from 3.8 to 4.8 V, users were predicted to inhale formaldehyde (up to 49 mg day-1), acrolein (up to 10 mg day-1) and diacetyl (up to 0.5 mg day-1), at levels that exceeded U.S. occupational limits. Formaldehyde intake from 100 daily puffs was higher than the amount inhaled by a smoker consuming 10 conventional cigarettes per day. Secondhand exposures were predicted for two typical indoor scenarios: a home and a bar. Contributions from vaping to air pollutant concentrations in the home did not exceed the California OEHHA 8-h reference exposure levels (RELs), except when a high emitting device was used at 4.8 V. In that extreme scenario, the contributions from vaping amounted to as much as 12 μg m-3 formaldehyde and 2.6 μg m-3 acrolein. Pollutant concentrations in bars were modeled using indoor volumes, air exchange rates and the number of hourly users reported in the literature for U.S. bars in which smoking was allowed. Predicted contributions to indoor air levels were higher than those in the residential scenario. Formaldehyde (on average 135 μg m-3) and acrolein (28 μg m-3) exceeded the acute 1-h exposure REL for the highest emitting vaporizer/voltage combination. Predictions for these compounds also exceeded the 8-h REL in several bars when less intense vaping conditions were considered. Benzene concentrations in a few bars approached the 8-h REL, and diacetyl levels were close to the lower limit for occupational exposures. The integrated health damage from passive vaping was derived by computing disability-adjusted life years (DALYs) lost due to exposure to secondhand vapor. Acrolein was the dominant contributor to the aggregate harm. DALYs for the various device/voltage combinations were lower than - or comparable to - those estimated for exposures to secondhand and thirdhand tobacco smoke.
Fil: Logue, Jennifer M.. Lawrence Berkeley National Laboratory. Environmental Energy Technologies División. Indoor Environment Group; Estados Unidos
Fil: Sleiman, Mohamad. Lawrence Berkeley National Laboratory. Environmental Energy Technologies División. Indoor Environment Group; Estados Unidos. Institut de Chimie de Clermont-ferrand; Francia
Fil: Montesinos, Victor Nahuel. Comisión Nacional de Energía Atómica. Gerencia del Área de Seguridad Nuclear y Ambiente. Gerencia de Química (CAC); Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Russell, Marion L.. Lawrence Berkeley National Laboratory. Environmental Energy Technologies División. Indoor Environment Group; Estados Unidos
Fil: Litter, Marta Irene. Universidad Nacional de San Martín. Instituto de Investigación en Ingeniería Ambiental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica. Gerencia del Área de Seguridad Nuclear y Ambiente. Gerencia de Química (CAC); Argentina
Fil: Benowitz, Neal L.. University Of San Francisco.; Estados Unidos
Fil: Gundel, Lara A.. Lawrence Berkeley National Laboratory. Environmental Energy Technologies División. Indoor Environment Group; Estados Unidos
Fil: Destaillats, Hugo. Lawrence Berkeley National Laboratory. Environmental Energy Technologies División. Indoor Environment Group; Estados Unidos
description E-cigarettes likely represent a lower risk to health than traditional combustion cigarettes, but they are not innocuous. Recently reported emission rates of potentially harmful compounds were used to assess intake and predict health impacts for vapers and bystanders exposed passively. Vapers' toxicant intake was calculated for scenarios in which different e-liquids were used with various vaporizers, battery power settings and vaping regimes. For a high rate of 250 puff day-1 using a typical vaping regime and popular tank devices with battery voltages from 3.8 to 4.8 V, users were predicted to inhale formaldehyde (up to 49 mg day-1), acrolein (up to 10 mg day-1) and diacetyl (up to 0.5 mg day-1), at levels that exceeded U.S. occupational limits. Formaldehyde intake from 100 daily puffs was higher than the amount inhaled by a smoker consuming 10 conventional cigarettes per day. Secondhand exposures were predicted for two typical indoor scenarios: a home and a bar. Contributions from vaping to air pollutant concentrations in the home did not exceed the California OEHHA 8-h reference exposure levels (RELs), except when a high emitting device was used at 4.8 V. In that extreme scenario, the contributions from vaping amounted to as much as 12 μg m-3 formaldehyde and 2.6 μg m-3 acrolein. Pollutant concentrations in bars were modeled using indoor volumes, air exchange rates and the number of hourly users reported in the literature for U.S. bars in which smoking was allowed. Predicted contributions to indoor air levels were higher than those in the residential scenario. Formaldehyde (on average 135 μg m-3) and acrolein (28 μg m-3) exceeded the acute 1-h exposure REL for the highest emitting vaporizer/voltage combination. Predictions for these compounds also exceeded the 8-h REL in several bars when less intense vaping conditions were considered. Benzene concentrations in a few bars approached the 8-h REL, and diacetyl levels were close to the lower limit for occupational exposures. The integrated health damage from passive vaping was derived by computing disability-adjusted life years (DALYs) lost due to exposure to secondhand vapor. Acrolein was the dominant contributor to the aggregate harm. DALYs for the various device/voltage combinations were lower than - or comparable to - those estimated for exposures to secondhand and thirdhand tobacco smoke.
publishDate 2017
dc.date.none.fl_str_mv 2017-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/117569
Logue, Jennifer M.; Sleiman, Mohamad; Montesinos, Victor Nahuel; Russell, Marion L.; Litter, Marta Irene; et al.; Emissions from Electronic Cigarettes: Assessing Vapers’ Intake of Toxic Compounds, Secondhand Exposures, and the Associated Health Impacts; American Chemical Society; Environmental Science & Technology; 51; 16; 8-2017; 9271-9279
0013-936X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/117569
identifier_str_mv Logue, Jennifer M.; Sleiman, Mohamad; Montesinos, Victor Nahuel; Russell, Marion L.; Litter, Marta Irene; et al.; Emissions from Electronic Cigarettes: Assessing Vapers’ Intake of Toxic Compounds, Secondhand Exposures, and the Associated Health Impacts; American Chemical Society; Environmental Science & Technology; 51; 16; 8-2017; 9271-9279
0013-936X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://pubs.acs.org/doi/abs/10.1021/acs.est.7b00710
info:eu-repo/semantics/altIdentifier/doi/10.1021/acs.est.7b00710
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dc.publisher.none.fl_str_mv American Chemical Society
publisher.none.fl_str_mv American Chemical Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
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