Superhydrophobic surfaces as a source of airborne singlet oxygen through free space for photodynamic therapy

Autores
Aebisher, David; Bartusik-Aebisher, Dorota; Belh, Sarah J.; Ghosh, Goutam; Durantini, Andres Matías; Liu, Yang; Xu, QianFeng; Lyons, Alan M.; Greer, Alexander
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A superhydrophobic (SH) sandwich system has been developed to enable "contact-free" airborne singlet oxygen (1O2) delivery to a water droplet. The contact-free feature means that the sensitizer is physically separated from the droplet, which presents opportunities for photodynamic therapy (PDT). Trapping of airborne 1O2 in a H2O droplet residing on a lower SH surface was monitored with 9,10-anthracene dipropionate dianion by varying distances to an upper 1O2-generating surface. Short distances of 20 μm efficiently delivered airborne 1O2 to the droplet in single-digit picomolar steady-state concentrations. Delivery decreases linearly with distance, but 50% of the 1O2 steady-state concentration is trapped at a distance of 300 μm from the generating surface. The 1270 nm luminescence intensity was measured within the SH sandwich system, confirming the presence of airborne 1O2. Physical quenching of 1O2 to ground-state 3O2 by the water droplet itself and both physical and chemical quenching of 1O2 by the water droplet containing the trap 9,10-anthracene dipropionate dianion are observed. Unlike a majority of work in the field of PDT with dissolved sensitizers, where 1O2 diffuses short (hundreds of nanometers) distances, we show the delivery of airborne 1O2 via a superhydrophobic surface is effective through air in tenths of millimeters distances to oxidize an organic compound in water. Our results provide not only potential relevance to PDT but also surface bacterial inactivation processes.
Fil: Aebisher, David. University Of Rzeszow; Polonia
Fil: Bartusik-Aebisher, Dorota. University Of Rzeszow; Polonia
Fil: Belh, Sarah J.. City University of New York; Estados Unidos
Fil: Ghosh, Goutam. City University of New York; Estados Unidos
Fil: Durantini, Andres Matías. Universidad Nacional de Río Cuarto. Instituto para el Desarrollo Agroindustrial y de la Salud. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto para el Desarrollo Agroindustrial y de la Salud; Argentina
Fil: Liu, Yang. City University of New York; Estados Unidos
Fil: Xu, QianFeng. City University of New York; Estados Unidos
Fil: Lyons, Alan M.. City University of New York; Estados Unidos
Fil: Greer, Alexander. City University of New York; Estados Unidos
Materia
LIQUID DROPLET
NEAR IR DETECTION
PHOTODYNAMIC THERAPY
PHYSICAL QUENCHING
SINGLET OXYGEN
SUPERHYDROPHOBIC SURFACE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/136283
Acceder
id CONICETDig_6c942671dbdd7b5883c87fbb387dfca6
oai_identifier_str oai:ri.conicet.gov.ar:11336/136283
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Superhydrophobic surfaces as a source of airborne singlet oxygen through free space for photodynamic therapyAebisher, DavidBartusik-Aebisher, DorotaBelh, Sarah J.Ghosh, GoutamDurantini, Andres MatíasLiu, YangXu, QianFengLyons, Alan M.Greer, AlexanderLIQUID DROPLETNEAR IR DETECTIONPHOTODYNAMIC THERAPYPHYSICAL QUENCHINGSINGLET OXYGENSUPERHYDROPHOBIC SURFACEhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1A superhydrophobic (SH) sandwich system has been developed to enable "contact-free" airborne singlet oxygen (1O2) delivery to a water droplet. The contact-free feature means that the sensitizer is physically separated from the droplet, which presents opportunities for photodynamic therapy (PDT). Trapping of airborne 1O2 in a H2O droplet residing on a lower SH surface was monitored with 9,10-anthracene dipropionate dianion by varying distances to an upper 1O2-generating surface. Short distances of 20 μm efficiently delivered airborne 1O2 to the droplet in single-digit picomolar steady-state concentrations. Delivery decreases linearly with distance, but 50% of the 1O2 steady-state concentration is trapped at a distance of 300 μm from the generating surface. The 1270 nm luminescence intensity was measured within the SH sandwich system, confirming the presence of airborne 1O2. Physical quenching of 1O2 to ground-state 3O2 by the water droplet itself and both physical and chemical quenching of 1O2 by the water droplet containing the trap 9,10-anthracene dipropionate dianion are observed. Unlike a majority of work in the field of PDT with dissolved sensitizers, where 1O2 diffuses short (hundreds of nanometers) distances, we show the delivery of airborne 1O2 via a superhydrophobic surface is effective through air in tenths of millimeters distances to oxidize an organic compound in water. Our results provide not only potential relevance to PDT but also surface bacterial inactivation processes.Fil: Aebisher, David. University Of Rzeszow; PoloniaFil: Bartusik-Aebisher, Dorota. University Of Rzeszow; PoloniaFil: Belh, Sarah J.. City University of New York; Estados UnidosFil: Ghosh, Goutam. City University of New York; Estados UnidosFil: Durantini, Andres Matías. Universidad Nacional de Río Cuarto. Instituto para el Desarrollo Agroindustrial y de la Salud. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto para el Desarrollo Agroindustrial y de la Salud; ArgentinaFil: Liu, Yang. City University of New York; Estados UnidosFil: Xu, QianFeng. City University of New York; Estados UnidosFil: Lyons, Alan M.. City University of New York; Estados UnidosFil: Greer, Alexander. City University of New York; Estados UnidosAmerican Chemical Society2020-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/136283Aebisher, David; Bartusik-Aebisher, Dorota; Belh, Sarah J.; Ghosh, Goutam; Durantini, Andres Matías; et al.; Superhydrophobic surfaces as a source of airborne singlet oxygen through free space for photodynamic therapy; American Chemical Society; ACS Applied Bio Materials; 3; 4; 4-2020; 2370-23772576-64222576-6422CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/10.1021/acsabm.0c00114info:eu-repo/semantics/altIdentifier/doi/10.1021/acsabm.0c00114info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:11:18Zoai:ri.conicet.gov.ar:11336/136283instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:11:19.21CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Superhydrophobic surfaces as a source of airborne singlet oxygen through free space for photodynamic therapy
title Superhydrophobic surfaces as a source of airborne singlet oxygen through free space for photodynamic therapy
spellingShingle Superhydrophobic surfaces as a source of airborne singlet oxygen through free space for photodynamic therapy
Aebisher, David
LIQUID DROPLET
NEAR IR DETECTION
PHOTODYNAMIC THERAPY
PHYSICAL QUENCHING
SINGLET OXYGEN
SUPERHYDROPHOBIC SURFACE
title_short Superhydrophobic surfaces as a source of airborne singlet oxygen through free space for photodynamic therapy
title_full Superhydrophobic surfaces as a source of airborne singlet oxygen through free space for photodynamic therapy
title_fullStr Superhydrophobic surfaces as a source of airborne singlet oxygen through free space for photodynamic therapy
title_full_unstemmed Superhydrophobic surfaces as a source of airborne singlet oxygen through free space for photodynamic therapy
title_sort Superhydrophobic surfaces as a source of airborne singlet oxygen through free space for photodynamic therapy
dc.creator.none.fl_str_mv Aebisher, David
Bartusik-Aebisher, Dorota
Belh, Sarah J.
Ghosh, Goutam
Durantini, Andres Matías
Liu, Yang
Xu, QianFeng
Lyons, Alan M.
Greer, Alexander
author Aebisher, David
author_facet Aebisher, David
Bartusik-Aebisher, Dorota
Belh, Sarah J.
Ghosh, Goutam
Durantini, Andres Matías
Liu, Yang
Xu, QianFeng
Lyons, Alan M.
Greer, Alexander
author_role author
author2 Bartusik-Aebisher, Dorota
Belh, Sarah J.
Ghosh, Goutam
Durantini, Andres Matías
Liu, Yang
Xu, QianFeng
Lyons, Alan M.
Greer, Alexander
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv LIQUID DROPLET
NEAR IR DETECTION
PHOTODYNAMIC THERAPY
PHYSICAL QUENCHING
SINGLET OXYGEN
SUPERHYDROPHOBIC SURFACE
topic LIQUID DROPLET
NEAR IR DETECTION
PHOTODYNAMIC THERAPY
PHYSICAL QUENCHING
SINGLET OXYGEN
SUPERHYDROPHOBIC SURFACE
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv A superhydrophobic (SH) sandwich system has been developed to enable "contact-free" airborne singlet oxygen (1O2) delivery to a water droplet. The contact-free feature means that the sensitizer is physically separated from the droplet, which presents opportunities for photodynamic therapy (PDT). Trapping of airborne 1O2 in a H2O droplet residing on a lower SH surface was monitored with 9,10-anthracene dipropionate dianion by varying distances to an upper 1O2-generating surface. Short distances of 20 μm efficiently delivered airborne 1O2 to the droplet in single-digit picomolar steady-state concentrations. Delivery decreases linearly with distance, but 50% of the 1O2 steady-state concentration is trapped at a distance of 300 μm from the generating surface. The 1270 nm luminescence intensity was measured within the SH sandwich system, confirming the presence of airborne 1O2. Physical quenching of 1O2 to ground-state 3O2 by the water droplet itself and both physical and chemical quenching of 1O2 by the water droplet containing the trap 9,10-anthracene dipropionate dianion are observed. Unlike a majority of work in the field of PDT with dissolved sensitizers, where 1O2 diffuses short (hundreds of nanometers) distances, we show the delivery of airborne 1O2 via a superhydrophobic surface is effective through air in tenths of millimeters distances to oxidize an organic compound in water. Our results provide not only potential relevance to PDT but also surface bacterial inactivation processes.
Fil: Aebisher, David. University Of Rzeszow; Polonia
Fil: Bartusik-Aebisher, Dorota. University Of Rzeszow; Polonia
Fil: Belh, Sarah J.. City University of New York; Estados Unidos
Fil: Ghosh, Goutam. City University of New York; Estados Unidos
Fil: Durantini, Andres Matías. Universidad Nacional de Río Cuarto. Instituto para el Desarrollo Agroindustrial y de la Salud. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto para el Desarrollo Agroindustrial y de la Salud; Argentina
Fil: Liu, Yang. City University of New York; Estados Unidos
Fil: Xu, QianFeng. City University of New York; Estados Unidos
Fil: Lyons, Alan M.. City University of New York; Estados Unidos
Fil: Greer, Alexander. City University of New York; Estados Unidos
description A superhydrophobic (SH) sandwich system has been developed to enable "contact-free" airborne singlet oxygen (1O2) delivery to a water droplet. The contact-free feature means that the sensitizer is physically separated from the droplet, which presents opportunities for photodynamic therapy (PDT). Trapping of airborne 1O2 in a H2O droplet residing on a lower SH surface was monitored with 9,10-anthracene dipropionate dianion by varying distances to an upper 1O2-generating surface. Short distances of 20 μm efficiently delivered airborne 1O2 to the droplet in single-digit picomolar steady-state concentrations. Delivery decreases linearly with distance, but 50% of the 1O2 steady-state concentration is trapped at a distance of 300 μm from the generating surface. The 1270 nm luminescence intensity was measured within the SH sandwich system, confirming the presence of airborne 1O2. Physical quenching of 1O2 to ground-state 3O2 by the water droplet itself and both physical and chemical quenching of 1O2 by the water droplet containing the trap 9,10-anthracene dipropionate dianion are observed. Unlike a majority of work in the field of PDT with dissolved sensitizers, where 1O2 diffuses short (hundreds of nanometers) distances, we show the delivery of airborne 1O2 via a superhydrophobic surface is effective through air in tenths of millimeters distances to oxidize an organic compound in water. Our results provide not only potential relevance to PDT but also surface bacterial inactivation processes.
publishDate 2020
dc.date.none.fl_str_mv 2020-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/136283
Aebisher, David; Bartusik-Aebisher, Dorota; Belh, Sarah J.; Ghosh, Goutam; Durantini, Andres Matías; et al.; Superhydrophobic surfaces as a source of airborne singlet oxygen through free space for photodynamic therapy; American Chemical Society; ACS Applied Bio Materials; 3; 4; 4-2020; 2370-2377
2576-6422
2576-6422
CONICET Digital
CONICET
url http://hdl.handle.net/11336/136283
identifier_str_mv Aebisher, David; Bartusik-Aebisher, Dorota; Belh, Sarah J.; Ghosh, Goutam; Durantini, Andres Matías; et al.; Superhydrophobic surfaces as a source of airborne singlet oxygen through free space for photodynamic therapy; American Chemical Society; ACS Applied Bio Materials; 3; 4; 4-2020; 2370-2377
2576-6422
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/10.1021/acsabm.0c00114
info:eu-repo/semantics/altIdentifier/doi/10.1021/acsabm.0c00114
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Chemical Society
publisher.none.fl_str_mv American Chemical Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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