Potassium thioacetate

Autores
Soria Castro, Silvia Mercedes
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Potassium thioacetate (AcSK) is an off-white to lightbrown crystalline powder that is air sensitive, hygroscopic, and commercially available. It is soluble in water and stable under standard temperature and pressure (m.p. 173–176 °C). This reagent is widely used as a sulfur source in the synthesis of sulfur-containing organic compounds. The formation of C–S bonds can be easily accomplished by reacting potassium thioacetate with aryl, benzyl, alkyl and vinyl halides or arenediazonium salts, to obtain the corresponding thioesters. A later deprotection allows straightforward access to the thiol since acyl groups may be removed under mild conditions. Thus, potassium thioacetate is a versatile reagent that can participate in numerous reactions such as nucleophilic substitutions, transition-metal-catalyzed couplings, photoinduced substitutions, vinylic substitutions and reductive amidation of nitro arenes. Therefore, this reagent has been employed for the synthesis of heterocycles,1 polymers,2 transition-metal ligands,3 nanoparticles,4 bioactive compounds5 and macromolecular inclusion complexes
Fil: Soria Castro, Silvia Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Materia
Potassium Thioacetate
Crystalline Powder
Reactions
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/63154
Acceder
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spelling Potassium thioacetateSoria Castro, Silvia MercedesPotassium ThioacetateCrystalline PowderReactionshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Potassium thioacetate (AcSK) is an off-white to lightbrown crystalline powder that is air sensitive, hygroscopic, and commercially available. It is soluble in water and stable under standard temperature and pressure (m.p. 173–176 °C). This reagent is widely used as a sulfur source in the synthesis of sulfur-containing organic compounds. The formation of C–S bonds can be easily accomplished by reacting potassium thioacetate with aryl, benzyl, alkyl and vinyl halides or arenediazonium salts, to obtain the corresponding thioesters. A later deprotection allows straightforward access to the thiol since acyl groups may be removed under mild conditions. Thus, potassium thioacetate is a versatile reagent that can participate in numerous reactions such as nucleophilic substitutions, transition-metal-catalyzed couplings, photoinduced substitutions, vinylic substitutions and reductive amidation of nitro arenes. Therefore, this reagent has been employed for the synthesis of heterocycles,1 polymers,2 transition-metal ligands,3 nanoparticles,4 bioactive compounds5 and macromolecular inclusion complexesFil: Soria Castro, Silvia Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaGeorg Thieme Verlag Kg2012-11-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/63154Soria Castro, Silvia Mercedes; Potassium thioacetate; Georg Thieme Verlag Kg; Synlett; 23; 20; 16-11-2012; 2997-29980936-52140936-5214CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.thieme-connect.de/DOI/DOI?10.1055/s-0031-1290470info:eu-repo/semantics/altIdentifier/doi/10.1055/s-0031-1290470info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:06:29Zoai:ri.conicet.gov.ar:11336/63154instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:06:29.661CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Potassium thioacetate
title Potassium thioacetate
spellingShingle Potassium thioacetate
Soria Castro, Silvia Mercedes
Potassium Thioacetate
Crystalline Powder
Reactions
title_short Potassium thioacetate
title_full Potassium thioacetate
title_fullStr Potassium thioacetate
title_full_unstemmed Potassium thioacetate
title_sort Potassium thioacetate
dc.creator.none.fl_str_mv Soria Castro, Silvia Mercedes
author Soria Castro, Silvia Mercedes
author_facet Soria Castro, Silvia Mercedes
author_role author
dc.subject.none.fl_str_mv Potassium Thioacetate
Crystalline Powder
Reactions
topic Potassium Thioacetate
Crystalline Powder
Reactions
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Potassium thioacetate (AcSK) is an off-white to lightbrown crystalline powder that is air sensitive, hygroscopic, and commercially available. It is soluble in water and stable under standard temperature and pressure (m.p. 173–176 °C). This reagent is widely used as a sulfur source in the synthesis of sulfur-containing organic compounds. The formation of C–S bonds can be easily accomplished by reacting potassium thioacetate with aryl, benzyl, alkyl and vinyl halides or arenediazonium salts, to obtain the corresponding thioesters. A later deprotection allows straightforward access to the thiol since acyl groups may be removed under mild conditions. Thus, potassium thioacetate is a versatile reagent that can participate in numerous reactions such as nucleophilic substitutions, transition-metal-catalyzed couplings, photoinduced substitutions, vinylic substitutions and reductive amidation of nitro arenes. Therefore, this reagent has been employed for the synthesis of heterocycles,1 polymers,2 transition-metal ligands,3 nanoparticles,4 bioactive compounds5 and macromolecular inclusion complexes
Fil: Soria Castro, Silvia Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
description Potassium thioacetate (AcSK) is an off-white to lightbrown crystalline powder that is air sensitive, hygroscopic, and commercially available. It is soluble in water and stable under standard temperature and pressure (m.p. 173–176 °C). This reagent is widely used as a sulfur source in the synthesis of sulfur-containing organic compounds. The formation of C–S bonds can be easily accomplished by reacting potassium thioacetate with aryl, benzyl, alkyl and vinyl halides or arenediazonium salts, to obtain the corresponding thioesters. A later deprotection allows straightforward access to the thiol since acyl groups may be removed under mild conditions. Thus, potassium thioacetate is a versatile reagent that can participate in numerous reactions such as nucleophilic substitutions, transition-metal-catalyzed couplings, photoinduced substitutions, vinylic substitutions and reductive amidation of nitro arenes. Therefore, this reagent has been employed for the synthesis of heterocycles,1 polymers,2 transition-metal ligands,3 nanoparticles,4 bioactive compounds5 and macromolecular inclusion complexes
publishDate 2012
dc.date.none.fl_str_mv 2012-11-16
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/63154
Soria Castro, Silvia Mercedes; Potassium thioacetate; Georg Thieme Verlag Kg; Synlett; 23; 20; 16-11-2012; 2997-2998
0936-5214
0936-5214
CONICET Digital
CONICET
url http://hdl.handle.net/11336/63154
identifier_str_mv Soria Castro, Silvia Mercedes; Potassium thioacetate; Georg Thieme Verlag Kg; Synlett; 23; 20; 16-11-2012; 2997-2998
0936-5214
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.thieme-connect.de/DOI/DOI?10.1055/s-0031-1290470
info:eu-repo/semantics/altIdentifier/doi/10.1055/s-0031-1290470
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Georg Thieme Verlag Kg
publisher.none.fl_str_mv Georg Thieme Verlag Kg
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846781363791855616
score 12.982451

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