An efficient and green catalytic method for friedländer quinoline synthesis using tungstophosphoric acid Included in a polymeric matrix

Autores
Bennardi, Daniel Oscar; Blanco, Mirta Noemi; Pizzio, Luis Rene; Autino, Juan Carlos; Romanelli, Gustavo Pablo
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A new, efficient and green methodology for obtaining quinolines based on the use of tungstophosphoric acid included in a polymeric matrix of polyacrylamide is proposed (APTPOL60). The methodology involves the formation of polysubstituted quinoline compounds using a variety of 2-aminoaryl ketones and -dicarbonyl compounds, in absolute ethanol as reaction solvent, and a temperature of 78ºC. The catalyst efficiency is not compromised after its successive use in reactions, and no leaching was observed. Seven examples of quinolone derivatives were obtained with excellent yields (89%-99%). This is the first report about the use of a heteropolyacid included in a polymeric matrix as recyclable catalyst in the Friedländer synthesis of quinoline derivatives (molecules with biological activity potential).
Fil: Bennardi, Daniel Oscar. Universidad Nacional de la Plata. Facultad de Ciencias Agrarias y Forestales. Departamento de Ciencias Exactas. Catedra de Quimica Organica; Argentina
Fil: Blanco, Mirta Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigación y Desarrollo En Ciencias Aplicadas; Argentina
Fil: Pizzio, Luis Rene. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigación y Desarrollo En Ciencias Aplicadas; Argentina
Fil: Autino, Juan Carlos. Universidad Nacional de la Plata. Facultad de Ciencias Agrarias y Forestales. Departamento de Ciencias Exactas. Catedra de Quimica Organica; Argentina
Fil: Romanelli, Gustavo Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigación y Desarrollo En Ciencias Aplicadas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Agrarias y Forestales. Departamento de Ciencias Exactas. Catedra de Quimica Organica; Argentina
Materia
Quinolines
Tungstophosphoric Acid
Polymeric Matrix
Heterogeneous Catalysts
Friedländer Synthesis
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/6040
Acceder
id CONICETDig_67e78a59a7e622de3176792df160cd54
oai_identifier_str oai:ri.conicet.gov.ar:11336/6040
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling An efficient and green catalytic method for friedländer quinoline synthesis using tungstophosphoric acid Included in a polymeric matrixBennardi, Daniel OscarBlanco, Mirta NoemiPizzio, Luis ReneAutino, Juan CarlosRomanelli, Gustavo PabloQuinolinesTungstophosphoric AcidPolymeric MatrixHeterogeneous CatalystsFriedländer Synthesishttps://purl.org/becyt/ford/2.4https://purl.org/becyt/ford/2https://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1A new, efficient and green methodology for obtaining quinolines based on the use of tungstophosphoric acid included in a polymeric matrix of polyacrylamide is proposed (APTPOL60). The methodology involves the formation of polysubstituted quinoline compounds using a variety of 2-aminoaryl ketones and -dicarbonyl compounds, in absolute ethanol as reaction solvent, and a temperature of 78ºC. The catalyst efficiency is not compromised after its successive use in reactions, and no leaching was observed. Seven examples of quinolone derivatives were obtained with excellent yields (89%-99%). This is the first report about the use of a heteropolyacid included in a polymeric matrix as recyclable catalyst in the Friedländer synthesis of quinoline derivatives (molecules with biological activity potential).Fil: Bennardi, Daniel Oscar. Universidad Nacional de la Plata. Facultad de Ciencias Agrarias y Forestales. Departamento de Ciencias Exactas. Catedra de Quimica Organica; ArgentinaFil: Blanco, Mirta Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigación y Desarrollo En Ciencias Aplicadas; ArgentinaFil: Pizzio, Luis Rene. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigación y Desarrollo En Ciencias Aplicadas; ArgentinaFil: Autino, Juan Carlos. Universidad Nacional de la Plata. Facultad de Ciencias Agrarias y Forestales. Departamento de Ciencias Exactas. Catedra de Quimica Organica; ArgentinaFil: Romanelli, Gustavo Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigación y Desarrollo En Ciencias Aplicadas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Agrarias y Forestales. Departamento de Ciencias Exactas. Catedra de Quimica Organica; ArgentinaBentham Science Publishers2015-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/6040Bennardi, Daniel Oscar; Blanco, Mirta Noemi; Pizzio, Luis Rene; Autino, Juan Carlos; Romanelli, Gustavo Pablo; An efficient and green catalytic method for friedländer quinoline synthesis using tungstophosphoric acid Included in a polymeric matrix; Bentham Science Publishers; Current Catalysis; 4; 5-2015; 65-722211-54472211-5455enginfo:eu-repo/semantics/altIdentifier/doi/info:eu-repo/semantics/altIdentifier/doi/10.2174/2211544704666150424234036info:eu-repo/semantics/altIdentifier/url/http://www.eurekaselect.com/130609/articleinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-29T11:47:19Zoai:ri.conicet.gov.ar:11336/6040instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-29 11:47:20.271CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv An efficient and green catalytic method for friedländer quinoline synthesis using tungstophosphoric acid Included in a polymeric matrix
title An efficient and green catalytic method for friedländer quinoline synthesis using tungstophosphoric acid Included in a polymeric matrix
spellingShingle An efficient and green catalytic method for friedländer quinoline synthesis using tungstophosphoric acid Included in a polymeric matrix
Bennardi, Daniel Oscar
Quinolines
Tungstophosphoric Acid
Polymeric Matrix
Heterogeneous Catalysts
Friedländer Synthesis
title_short An efficient and green catalytic method for friedländer quinoline synthesis using tungstophosphoric acid Included in a polymeric matrix
title_full An efficient and green catalytic method for friedländer quinoline synthesis using tungstophosphoric acid Included in a polymeric matrix
title_fullStr An efficient and green catalytic method for friedländer quinoline synthesis using tungstophosphoric acid Included in a polymeric matrix
title_full_unstemmed An efficient and green catalytic method for friedländer quinoline synthesis using tungstophosphoric acid Included in a polymeric matrix
title_sort An efficient and green catalytic method for friedländer quinoline synthesis using tungstophosphoric acid Included in a polymeric matrix
dc.creator.none.fl_str_mv Bennardi, Daniel Oscar
Blanco, Mirta Noemi
Pizzio, Luis Rene
Autino, Juan Carlos
Romanelli, Gustavo Pablo
author Bennardi, Daniel Oscar
author_facet Bennardi, Daniel Oscar
Blanco, Mirta Noemi
Pizzio, Luis Rene
Autino, Juan Carlos
Romanelli, Gustavo Pablo
author_role author
author2 Blanco, Mirta Noemi
Pizzio, Luis Rene
Autino, Juan Carlos
Romanelli, Gustavo Pablo
author2_role author
author
author
author
dc.subject.none.fl_str_mv Quinolines
Tungstophosphoric Acid
Polymeric Matrix
Heterogeneous Catalysts
Friedländer Synthesis
topic Quinolines
Tungstophosphoric Acid
Polymeric Matrix
Heterogeneous Catalysts
Friedländer Synthesis
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.4
https://purl.org/becyt/ford/2
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv A new, efficient and green methodology for obtaining quinolines based on the use of tungstophosphoric acid included in a polymeric matrix of polyacrylamide is proposed (APTPOL60). The methodology involves the formation of polysubstituted quinoline compounds using a variety of 2-aminoaryl ketones and -dicarbonyl compounds, in absolute ethanol as reaction solvent, and a temperature of 78ºC. The catalyst efficiency is not compromised after its successive use in reactions, and no leaching was observed. Seven examples of quinolone derivatives were obtained with excellent yields (89%-99%). This is the first report about the use of a heteropolyacid included in a polymeric matrix as recyclable catalyst in the Friedländer synthesis of quinoline derivatives (molecules with biological activity potential).
Fil: Bennardi, Daniel Oscar. Universidad Nacional de la Plata. Facultad de Ciencias Agrarias y Forestales. Departamento de Ciencias Exactas. Catedra de Quimica Organica; Argentina
Fil: Blanco, Mirta Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigación y Desarrollo En Ciencias Aplicadas; Argentina
Fil: Pizzio, Luis Rene. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigación y Desarrollo En Ciencias Aplicadas; Argentina
Fil: Autino, Juan Carlos. Universidad Nacional de la Plata. Facultad de Ciencias Agrarias y Forestales. Departamento de Ciencias Exactas. Catedra de Quimica Organica; Argentina
Fil: Romanelli, Gustavo Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigación y Desarrollo En Ciencias Aplicadas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Agrarias y Forestales. Departamento de Ciencias Exactas. Catedra de Quimica Organica; Argentina
description A new, efficient and green methodology for obtaining quinolines based on the use of tungstophosphoric acid included in a polymeric matrix of polyacrylamide is proposed (APTPOL60). The methodology involves the formation of polysubstituted quinoline compounds using a variety of 2-aminoaryl ketones and -dicarbonyl compounds, in absolute ethanol as reaction solvent, and a temperature of 78ºC. The catalyst efficiency is not compromised after its successive use in reactions, and no leaching was observed. Seven examples of quinolone derivatives were obtained with excellent yields (89%-99%). This is the first report about the use of a heteropolyacid included in a polymeric matrix as recyclable catalyst in the Friedländer synthesis of quinoline derivatives (molecules with biological activity potential).
publishDate 2015
dc.date.none.fl_str_mv 2015-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/6040
Bennardi, Daniel Oscar; Blanco, Mirta Noemi; Pizzio, Luis Rene; Autino, Juan Carlos; Romanelli, Gustavo Pablo; An efficient and green catalytic method for friedländer quinoline synthesis using tungstophosphoric acid Included in a polymeric matrix; Bentham Science Publishers; Current Catalysis; 4; 5-2015; 65-72
2211-5447
2211-5455
url http://hdl.handle.net/11336/6040
identifier_str_mv Bennardi, Daniel Oscar; Blanco, Mirta Noemi; Pizzio, Luis Rene; Autino, Juan Carlos; Romanelli, Gustavo Pablo; An efficient and green catalytic method for friedländer quinoline synthesis using tungstophosphoric acid Included in a polymeric matrix; Bentham Science Publishers; Current Catalysis; 4; 5-2015; 65-72
2211-5447
2211-5455
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/
info:eu-repo/semantics/altIdentifier/doi/10.2174/2211544704666150424234036
info:eu-repo/semantics/altIdentifier/url/http://www.eurekaselect.com/130609/article
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Bentham Science Publishers
publisher.none.fl_str_mv Bentham Science Publishers
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1847426473582919680
score 13.10058

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