Epidemiology and spatial distribution of Echinococcus granulosus in sheep and goats slaughtered in a hyperendemic European Mediterranean area

Autores
Bosco, Antonio; Alves, Leucio Camara; Cociancic, Paola; Amadesi, Alessandra; Pepe, Paola; Morgoglione, Maria Elena; Maurelli, Maria Paola; Ferrer Miranda, Edyniesky; Santoro, Kleber Régis; Nascimento Ramos, Rafael Antonio; Rinaldi, Laura; Cringoli, Giuseppe
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: Cystic echinococcosis (CE) is a worldwide parasitic zoonosis caused by the larval stage of Echinococcus granulosus sensu lato affecting livestock, particularly sheep and goats. However, often this parasitosis is underestimated. For this reason, this study aimed to evaluate the epidemiological features and spatial distribution of CE in sheep and goats slaughtered in a hyperendemic Mediterranean area. Methods: A survey was conducted in the Basilicata region (southern Italy) from 2014 to 2019. A total of 1454 animals (1265 sheep and 189 goats) from 824 farms were examined for hydatid cyst detection by visual inspection, palpation and incision of target organs. All the CE cysts were counted and classified into five morphostructural types (unilocular, multiseptate, calcified, caseous and hyperlaminated). Molecular analysis was performed on 353 cysts. For spatial analysis, a kriging interpolation method was used to create risk maps, while clustering was assessed by Moran’s I test. Results: CE prevalence of 72.2% (595/824) and 58.4% (849/1454) was observed at the farm and animal levels, respectively, with higher values in sheep (62.9%) than goats (28.0%). The liver and lungs were the most frequently infected organs in both sheep and goats. Most of recovered cysts were of the calcified and multiseptate morphotypes. All the isolates were identified as E. granulosus sensu stricto (genotypes G1–G3). Spatial distribution showed a moderate clustering of positive animals. Conclusion: The findings of this study can be used to better understand the eco-epidemiology of echinococcosis and to improve CE surveillance and prevention programs in regions highly endemic for CE.
Fil: Bosco, Antonio. Università degli Studi di Napoli Federico II; Italia
Fil: Alves, Leucio Camara. Universidad Federal Rural Pernambuco; Brasil
Fil: Cociancic, Paola. Università degli Studi di Napoli Federico II; Italia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Estudios Parasitológicos y de Vectores. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Centro de Estudios Parasitológicos y de Vectores; Argentina
Fil: Amadesi, Alessandra. Università degli Studi di Napoli Federico II; Italia
Fil: Pepe, Paola. Università degli Studi di Napoli Federico II; Italia
Fil: Morgoglione, Maria Elena. Università degli Studi di Napoli Federico II; Italia
Fil: Maurelli, Maria Paola. Università degli Studi di Napoli Federico II; Italia
Fil: Ferrer Miranda, Edyniesky. Universidad Federal Rural Pernambuco; Brasil
Fil: Santoro, Kleber Régis. Universidad Federal Rural Pernambuco; Brasil
Fil: Nascimento Ramos, Rafael Antonio. Universidad Federal Rural Pernambuco; Brasil
Fil: Rinaldi, Laura. Università degli Studi di Napoli Federico II; Italia
Fil: Cringoli, Giuseppe. Università degli Studi di Napoli Federico II; Italia
Materia
CYSTIC ECHINOCOCCOSIS
CYSTS
ECHINOCOCCUS GRANULOSUS
GOATS
SHEEP
SPATIAL DISTRIBUTION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/181126
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/181126
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Epidemiology and spatial distribution of Echinococcus granulosus in sheep and goats slaughtered in a hyperendemic European Mediterranean areaBosco, AntonioAlves, Leucio CamaraCociancic, PaolaAmadesi, AlessandraPepe, PaolaMorgoglione, Maria ElenaMaurelli, Maria PaolaFerrer Miranda, EdynieskySantoro, Kleber RégisNascimento Ramos, Rafael AntonioRinaldi, LauraCringoli, GiuseppeCYSTIC ECHINOCOCCOSISCYSTSECHINOCOCCUS GRANULOSUSGOATSSHEEPSPATIAL DISTRIBUTIONhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Background: Cystic echinococcosis (CE) is a worldwide parasitic zoonosis caused by the larval stage of Echinococcus granulosus sensu lato affecting livestock, particularly sheep and goats. However, often this parasitosis is underestimated. For this reason, this study aimed to evaluate the epidemiological features and spatial distribution of CE in sheep and goats slaughtered in a hyperendemic Mediterranean area. Methods: A survey was conducted in the Basilicata region (southern Italy) from 2014 to 2019. A total of 1454 animals (1265 sheep and 189 goats) from 824 farms were examined for hydatid cyst detection by visual inspection, palpation and incision of target organs. All the CE cysts were counted and classified into five morphostructural types (unilocular, multiseptate, calcified, caseous and hyperlaminated). Molecular analysis was performed on 353 cysts. For spatial analysis, a kriging interpolation method was used to create risk maps, while clustering was assessed by Moran’s I test. Results: CE prevalence of 72.2% (595/824) and 58.4% (849/1454) was observed at the farm and animal levels, respectively, with higher values in sheep (62.9%) than goats (28.0%). The liver and lungs were the most frequently infected organs in both sheep and goats. Most of recovered cysts were of the calcified and multiseptate morphotypes. All the isolates were identified as E. granulosus sensu stricto (genotypes G1–G3). Spatial distribution showed a moderate clustering of positive animals. Conclusion: The findings of this study can be used to better understand the eco-epidemiology of echinococcosis and to improve CE surveillance and prevention programs in regions highly endemic for CE.Fil: Bosco, Antonio. Università degli Studi di Napoli Federico II; ItaliaFil: Alves, Leucio Camara. Universidad Federal Rural Pernambuco; BrasilFil: Cociancic, Paola. Università degli Studi di Napoli Federico II; Italia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Estudios Parasitológicos y de Vectores. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Centro de Estudios Parasitológicos y de Vectores; ArgentinaFil: Amadesi, Alessandra. Università degli Studi di Napoli Federico II; ItaliaFil: Pepe, Paola. Università degli Studi di Napoli Federico II; ItaliaFil: Morgoglione, Maria Elena. Università degli Studi di Napoli Federico II; ItaliaFil: Maurelli, Maria Paola. Università degli Studi di Napoli Federico II; ItaliaFil: Ferrer Miranda, Edyniesky. Universidad Federal Rural Pernambuco; BrasilFil: Santoro, Kleber Régis. Universidad Federal Rural Pernambuco; BrasilFil: Nascimento Ramos, Rafael Antonio. Universidad Federal Rural Pernambuco; BrasilFil: Rinaldi, Laura. Università degli Studi di Napoli Federico II; ItaliaFil: Cringoli, Giuseppe. Università degli Studi di Napoli Federico II; ItaliaBioMed Central2021-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/181126Bosco, Antonio; Alves, Leucio Camara; Cociancic, Paola; Amadesi, Alessandra; Pepe, Paola; et al.; Epidemiology and spatial distribution of Echinococcus granulosus in sheep and goats slaughtered in a hyperendemic European Mediterranean area; BioMed Central; Parasites and Vectors; 14; 1; 12-2021; 1-91756-3305CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1186/s13071-021-04934-9info:eu-repo/semantics/altIdentifier/url/https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-021-04934-9info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:50:53Zoai:ri.conicet.gov.ar:11336/181126instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:50:53.655CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Epidemiology and spatial distribution of Echinococcus granulosus in sheep and goats slaughtered in a hyperendemic European Mediterranean area
title Epidemiology and spatial distribution of Echinococcus granulosus in sheep and goats slaughtered in a hyperendemic European Mediterranean area
spellingShingle Epidemiology and spatial distribution of Echinococcus granulosus in sheep and goats slaughtered in a hyperendemic European Mediterranean area
Bosco, Antonio
CYSTIC ECHINOCOCCOSIS
CYSTS
ECHINOCOCCUS GRANULOSUS
GOATS
SHEEP
SPATIAL DISTRIBUTION
title_short Epidemiology and spatial distribution of Echinococcus granulosus in sheep and goats slaughtered in a hyperendemic European Mediterranean area
title_full Epidemiology and spatial distribution of Echinococcus granulosus in sheep and goats slaughtered in a hyperendemic European Mediterranean area
title_fullStr Epidemiology and spatial distribution of Echinococcus granulosus in sheep and goats slaughtered in a hyperendemic European Mediterranean area
title_full_unstemmed Epidemiology and spatial distribution of Echinococcus granulosus in sheep and goats slaughtered in a hyperendemic European Mediterranean area
title_sort Epidemiology and spatial distribution of Echinococcus granulosus in sheep and goats slaughtered in a hyperendemic European Mediterranean area
dc.creator.none.fl_str_mv Bosco, Antonio
Alves, Leucio Camara
Cociancic, Paola
Amadesi, Alessandra
Pepe, Paola
Morgoglione, Maria Elena
Maurelli, Maria Paola
Ferrer Miranda, Edyniesky
Santoro, Kleber Régis
Nascimento Ramos, Rafael Antonio
Rinaldi, Laura
Cringoli, Giuseppe
author Bosco, Antonio
author_facet Bosco, Antonio
Alves, Leucio Camara
Cociancic, Paola
Amadesi, Alessandra
Pepe, Paola
Morgoglione, Maria Elena
Maurelli, Maria Paola
Ferrer Miranda, Edyniesky
Santoro, Kleber Régis
Nascimento Ramos, Rafael Antonio
Rinaldi, Laura
Cringoli, Giuseppe
author_role author
author2 Alves, Leucio Camara
Cociancic, Paola
Amadesi, Alessandra
Pepe, Paola
Morgoglione, Maria Elena
Maurelli, Maria Paola
Ferrer Miranda, Edyniesky
Santoro, Kleber Régis
Nascimento Ramos, Rafael Antonio
Rinaldi, Laura
Cringoli, Giuseppe
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv CYSTIC ECHINOCOCCOSIS
CYSTS
ECHINOCOCCUS GRANULOSUS
GOATS
SHEEP
SPATIAL DISTRIBUTION
topic CYSTIC ECHINOCOCCOSIS
CYSTS
ECHINOCOCCUS GRANULOSUS
GOATS
SHEEP
SPATIAL DISTRIBUTION
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Background: Cystic echinococcosis (CE) is a worldwide parasitic zoonosis caused by the larval stage of Echinococcus granulosus sensu lato affecting livestock, particularly sheep and goats. However, often this parasitosis is underestimated. For this reason, this study aimed to evaluate the epidemiological features and spatial distribution of CE in sheep and goats slaughtered in a hyperendemic Mediterranean area. Methods: A survey was conducted in the Basilicata region (southern Italy) from 2014 to 2019. A total of 1454 animals (1265 sheep and 189 goats) from 824 farms were examined for hydatid cyst detection by visual inspection, palpation and incision of target organs. All the CE cysts were counted and classified into five morphostructural types (unilocular, multiseptate, calcified, caseous and hyperlaminated). Molecular analysis was performed on 353 cysts. For spatial analysis, a kriging interpolation method was used to create risk maps, while clustering was assessed by Moran’s I test. Results: CE prevalence of 72.2% (595/824) and 58.4% (849/1454) was observed at the farm and animal levels, respectively, with higher values in sheep (62.9%) than goats (28.0%). The liver and lungs were the most frequently infected organs in both sheep and goats. Most of recovered cysts were of the calcified and multiseptate morphotypes. All the isolates were identified as E. granulosus sensu stricto (genotypes G1–G3). Spatial distribution showed a moderate clustering of positive animals. Conclusion: The findings of this study can be used to better understand the eco-epidemiology of echinococcosis and to improve CE surveillance and prevention programs in regions highly endemic for CE.
Fil: Bosco, Antonio. Università degli Studi di Napoli Federico II; Italia
Fil: Alves, Leucio Camara. Universidad Federal Rural Pernambuco; Brasil
Fil: Cociancic, Paola. Università degli Studi di Napoli Federico II; Italia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Estudios Parasitológicos y de Vectores. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Centro de Estudios Parasitológicos y de Vectores; Argentina
Fil: Amadesi, Alessandra. Università degli Studi di Napoli Federico II; Italia
Fil: Pepe, Paola. Università degli Studi di Napoli Federico II; Italia
Fil: Morgoglione, Maria Elena. Università degli Studi di Napoli Federico II; Italia
Fil: Maurelli, Maria Paola. Università degli Studi di Napoli Federico II; Italia
Fil: Ferrer Miranda, Edyniesky. Universidad Federal Rural Pernambuco; Brasil
Fil: Santoro, Kleber Régis. Universidad Federal Rural Pernambuco; Brasil
Fil: Nascimento Ramos, Rafael Antonio. Universidad Federal Rural Pernambuco; Brasil
Fil: Rinaldi, Laura. Università degli Studi di Napoli Federico II; Italia
Fil: Cringoli, Giuseppe. Università degli Studi di Napoli Federico II; Italia
description Background: Cystic echinococcosis (CE) is a worldwide parasitic zoonosis caused by the larval stage of Echinococcus granulosus sensu lato affecting livestock, particularly sheep and goats. However, often this parasitosis is underestimated. For this reason, this study aimed to evaluate the epidemiological features and spatial distribution of CE in sheep and goats slaughtered in a hyperendemic Mediterranean area. Methods: A survey was conducted in the Basilicata region (southern Italy) from 2014 to 2019. A total of 1454 animals (1265 sheep and 189 goats) from 824 farms were examined for hydatid cyst detection by visual inspection, palpation and incision of target organs. All the CE cysts were counted and classified into five morphostructural types (unilocular, multiseptate, calcified, caseous and hyperlaminated). Molecular analysis was performed on 353 cysts. For spatial analysis, a kriging interpolation method was used to create risk maps, while clustering was assessed by Moran’s I test. Results: CE prevalence of 72.2% (595/824) and 58.4% (849/1454) was observed at the farm and animal levels, respectively, with higher values in sheep (62.9%) than goats (28.0%). The liver and lungs were the most frequently infected organs in both sheep and goats. Most of recovered cysts were of the calcified and multiseptate morphotypes. All the isolates were identified as E. granulosus sensu stricto (genotypes G1–G3). Spatial distribution showed a moderate clustering of positive animals. Conclusion: The findings of this study can be used to better understand the eco-epidemiology of echinococcosis and to improve CE surveillance and prevention programs in regions highly endemic for CE.
publishDate 2021
dc.date.none.fl_str_mv 2021-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/181126
Bosco, Antonio; Alves, Leucio Camara; Cociancic, Paola; Amadesi, Alessandra; Pepe, Paola; et al.; Epidemiology and spatial distribution of Echinococcus granulosus in sheep and goats slaughtered in a hyperendemic European Mediterranean area; BioMed Central; Parasites and Vectors; 14; 1; 12-2021; 1-9
1756-3305
CONICET Digital
CONICET
url http://hdl.handle.net/11336/181126
identifier_str_mv Bosco, Antonio; Alves, Leucio Camara; Cociancic, Paola; Amadesi, Alessandra; Pepe, Paola; et al.; Epidemiology and spatial distribution of Echinococcus granulosus in sheep and goats slaughtered in a hyperendemic European Mediterranean area; BioMed Central; Parasites and Vectors; 14; 1; 12-2021; 1-9
1756-3305
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1186/s13071-021-04934-9
info:eu-repo/semantics/altIdentifier/url/https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-021-04934-9
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
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instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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