Evaluation of thermal stability and sun protector factor values in vitro in O/W emulsions containing Benzophenone-3 and Avobenzone

Autores
Ceresole, Rita; Asero, Marta Delia; Han, Yong Ki; Rosasco, María Ana; Segall, Adriana Ines
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The purpose of this work is to study the thermal stability of benzophenone-3 and avobenzone in the presence and in the absence of TiO2, in O/W emulsions for sunscreens products. The emulsions were stored in glass containers at 40 °C and 75 % RH and at room temperature. Concomitantly the Sun Protector Factor (SPF) value was evaluated in vitro. These formulations seem to be more stable in the presence of diethylhexyl syringylidene malonate and titanium dioxide and silica. Avobenzone and benzophenone-3 seem to be less stable in the presence of caprylic capric triglyceride though this excipient increases the SPF in vitro value. Thus, the aim of this study was to evaluate the thermal stability by HPLC and the efficacy of formulations containing chemical filters, a physical filter and an antioxidant measuring the SPF in vitro value.
Fil: Ceresole, Rita. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Asero, Marta Delia. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Han, Yong Ki. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Rosasco, María Ana. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Segall, Adriana Ines. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Avobenzone
Benzophenone-3
Stability
Sps in Vitro
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/26789
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/26789
network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Evaluation of thermal stability and sun protector factor values in vitro in O/W emulsions containing Benzophenone-3 and AvobenzoneCeresole, RitaAsero, Marta DeliaHan, Yong KiRosasco, María AnaSegall, Adriana InesAvobenzoneBenzophenone-3StabilitySps in Vitrohttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3The purpose of this work is to study the thermal stability of benzophenone-3 and avobenzone in the presence and in the absence of TiO2, in O/W emulsions for sunscreens products. The emulsions were stored in glass containers at 40 °C and 75 % RH and at room temperature. Concomitantly the Sun Protector Factor (SPF) value was evaluated in vitro. These formulations seem to be more stable in the presence of diethylhexyl syringylidene malonate and titanium dioxide and silica. Avobenzone and benzophenone-3 seem to be less stable in the presence of caprylic capric triglyceride though this excipient increases the SPF in vitro value. Thus, the aim of this study was to evaluate the thermal stability by HPLC and the efficacy of formulations containing chemical filters, a physical filter and an antioxidant measuring the SPF in vitro value.Fil: Ceresole, Rita. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Asero, Marta Delia. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Han, Yong Ki. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Rosasco, María Ana. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Segall, Adriana Ines. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaColegio de Farmacéuticos de la Provincia de Buenos Aires2013-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/26789Ceresole, Rita; Asero, Marta Delia; Han, Yong Ki; Rosasco, María Ana; Segall, Adriana Ines; Evaluation of thermal stability and sun protector factor values in vitro in O/W emulsions containing Benzophenone-3 and Avobenzone; Colegio de Farmacéuticos de la Provincia de Buenos Aires; Latin American Journal of Pharmacy; 32; 5; 12-2013; 706-7112362-3853CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.latamjpharm.org/previous_issue.php?vol=32&num=5info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:02:21Zoai:ri.conicet.gov.ar:11336/26789instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:02:21.931CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Evaluation of thermal stability and sun protector factor values in vitro in O/W emulsions containing Benzophenone-3 and Avobenzone
title Evaluation of thermal stability and sun protector factor values in vitro in O/W emulsions containing Benzophenone-3 and Avobenzone
spellingShingle Evaluation of thermal stability and sun protector factor values in vitro in O/W emulsions containing Benzophenone-3 and Avobenzone
Ceresole, Rita
Avobenzone
Benzophenone-3
Stability
Sps in Vitro
title_short Evaluation of thermal stability and sun protector factor values in vitro in O/W emulsions containing Benzophenone-3 and Avobenzone
title_full Evaluation of thermal stability and sun protector factor values in vitro in O/W emulsions containing Benzophenone-3 and Avobenzone
title_fullStr Evaluation of thermal stability and sun protector factor values in vitro in O/W emulsions containing Benzophenone-3 and Avobenzone
title_full_unstemmed Evaluation of thermal stability and sun protector factor values in vitro in O/W emulsions containing Benzophenone-3 and Avobenzone
title_sort Evaluation of thermal stability and sun protector factor values in vitro in O/W emulsions containing Benzophenone-3 and Avobenzone
dc.creator.none.fl_str_mv Ceresole, Rita
Asero, Marta Delia
Han, Yong Ki
Rosasco, María Ana
Segall, Adriana Ines
author Ceresole, Rita
author_facet Ceresole, Rita
Asero, Marta Delia
Han, Yong Ki
Rosasco, María Ana
Segall, Adriana Ines
author_role author
author2 Asero, Marta Delia
Han, Yong Ki
Rosasco, María Ana
Segall, Adriana Ines
author2_role author
author
author
author
dc.subject.none.fl_str_mv Avobenzone
Benzophenone-3
Stability
Sps in Vitro
topic Avobenzone
Benzophenone-3
Stability
Sps in Vitro
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The purpose of this work is to study the thermal stability of benzophenone-3 and avobenzone in the presence and in the absence of TiO2, in O/W emulsions for sunscreens products. The emulsions were stored in glass containers at 40 °C and 75 % RH and at room temperature. Concomitantly the Sun Protector Factor (SPF) value was evaluated in vitro. These formulations seem to be more stable in the presence of diethylhexyl syringylidene malonate and titanium dioxide and silica. Avobenzone and benzophenone-3 seem to be less stable in the presence of caprylic capric triglyceride though this excipient increases the SPF in vitro value. Thus, the aim of this study was to evaluate the thermal stability by HPLC and the efficacy of formulations containing chemical filters, a physical filter and an antioxidant measuring the SPF in vitro value.
Fil: Ceresole, Rita. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Asero, Marta Delia. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Han, Yong Ki. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Rosasco, María Ana. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Segall, Adriana Ines. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description The purpose of this work is to study the thermal stability of benzophenone-3 and avobenzone in the presence and in the absence of TiO2, in O/W emulsions for sunscreens products. The emulsions were stored in glass containers at 40 °C and 75 % RH and at room temperature. Concomitantly the Sun Protector Factor (SPF) value was evaluated in vitro. These formulations seem to be more stable in the presence of diethylhexyl syringylidene malonate and titanium dioxide and silica. Avobenzone and benzophenone-3 seem to be less stable in the presence of caprylic capric triglyceride though this excipient increases the SPF in vitro value. Thus, the aim of this study was to evaluate the thermal stability by HPLC and the efficacy of formulations containing chemical filters, a physical filter and an antioxidant measuring the SPF in vitro value.
publishDate 2013
dc.date.none.fl_str_mv 2013-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/26789
Ceresole, Rita; Asero, Marta Delia; Han, Yong Ki; Rosasco, María Ana; Segall, Adriana Ines; Evaluation of thermal stability and sun protector factor values in vitro in O/W emulsions containing Benzophenone-3 and Avobenzone; Colegio de Farmacéuticos de la Provincia de Buenos Aires; Latin American Journal of Pharmacy; 32; 5; 12-2013; 706-711
2362-3853
CONICET Digital
CONICET
url http://hdl.handle.net/11336/26789
identifier_str_mv Ceresole, Rita; Asero, Marta Delia; Han, Yong Ki; Rosasco, María Ana; Segall, Adriana Ines; Evaluation of thermal stability and sun protector factor values in vitro in O/W emulsions containing Benzophenone-3 and Avobenzone; Colegio de Farmacéuticos de la Provincia de Buenos Aires; Latin American Journal of Pharmacy; 32; 5; 12-2013; 706-711
2362-3853
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.latamjpharm.org/previous_issue.php?vol=32&num=5
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Colegio de Farmacéuticos de la Provincia de Buenos Aires
publisher.none.fl_str_mv Colegio de Farmacéuticos de la Provincia de Buenos Aires
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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