It Cuts Both Ways: An Annelid Model System for the Study of Regeneration in the Laboratory and in the Classroom

Autores
Martinez Acosta, Veronica G.; Arellano Carbajal, Fausto; Gillen, Kathy; Tweeten, Kay A.; Zattara, Eduardo Enrique
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The mechanisms supporting regeneration and successful recovery of function have fascinated scientists and the general public for quite some time, with the earliest description of regeneration occurring in the 8th century BC through the Greek mythological story of Prometheus. While most animals demonstrate the capacity for wound-healing, the ability to initiate a developmental process that leads to a partial or complete replacement of a lost structure varies widely among animal taxa. Variation also occurs within single species based on the nature and location of the wound and the developmental stage or age of the individual. Comparative studies of cellular and molecular changes that occur both during, and following, wound healing may point to conserved genomic pathways among animals of different regenerative capacity. Such insights could revolutionize studies within the field of regenerative medicine. In this review, we focus on several closely related species of Lumbriculus (Clitellata: Lumbriculidae), as we present a case for revisiting the use of an annelid model system for the study of regeneration. We hope that this review will provide a primer to Lumbriculus biology not only for regeneration researchers but also for STEM teachers and their students.
Fil: Martinez Acosta, Veronica G.. University Of The Incarnate Word; Estados Unidos
Fil: Arellano Carbajal, Fausto. Universidad Autonoma de Queretaro.; México
Fil: Gillen, Kathy. Kenyon College; Estados Unidos
Fil: Tweeten, Kay A.. St. Catherine University; Estados Unidos
Fil: Zattara, Eduardo Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigaciones en Biodiversidad y Medioambiente. Universidad Nacional del Comahue. Centro Regional Universidad Bariloche. Instituto de Investigaciones en Biodiversidad y Medioambiente; Argentina. Indiana University; Estados Unidos. National Museum Of Natural History. Departamento de Zoología. Area de Invertebrados; Estados Unidos
Materia
CLITELLATE
INVERTEBRATE BIOLOGY
MOLECULAR RESOURCES
NEUROPHYSIOLOGY
STEM CELLS
STEM EDUCATION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/183574
Acceder
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spelling It Cuts Both Ways: An Annelid Model System for the Study of Regeneration in the Laboratory and in the ClassroomMartinez Acosta, Veronica G.Arellano Carbajal, FaustoGillen, KathyTweeten, Kay A.Zattara, Eduardo EnriqueCLITELLATEINVERTEBRATE BIOLOGYMOLECULAR RESOURCESNEUROPHYSIOLOGYSTEM CELLSSTEM EDUCATIONhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1https://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The mechanisms supporting regeneration and successful recovery of function have fascinated scientists and the general public for quite some time, with the earliest description of regeneration occurring in the 8th century BC through the Greek mythological story of Prometheus. While most animals demonstrate the capacity for wound-healing, the ability to initiate a developmental process that leads to a partial or complete replacement of a lost structure varies widely among animal taxa. Variation also occurs within single species based on the nature and location of the wound and the developmental stage or age of the individual. Comparative studies of cellular and molecular changes that occur both during, and following, wound healing may point to conserved genomic pathways among animals of different regenerative capacity. Such insights could revolutionize studies within the field of regenerative medicine. In this review, we focus on several closely related species of Lumbriculus (Clitellata: Lumbriculidae), as we present a case for revisiting the use of an annelid model system for the study of regeneration. We hope that this review will provide a primer to Lumbriculus biology not only for regeneration researchers but also for STEM teachers and their students.Fil: Martinez Acosta, Veronica G.. University Of The Incarnate Word; Estados UnidosFil: Arellano Carbajal, Fausto. Universidad Autonoma de Queretaro.; MéxicoFil: Gillen, Kathy. Kenyon College; Estados UnidosFil: Tweeten, Kay A.. St. Catherine University; Estados UnidosFil: Zattara, Eduardo Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigaciones en Biodiversidad y Medioambiente. Universidad Nacional del Comahue. Centro Regional Universidad Bariloche. Instituto de Investigaciones en Biodiversidad y Medioambiente; Argentina. Indiana University; Estados Unidos. National Museum Of Natural History. Departamento de Zoología. Area de Invertebrados; Estados UnidosFrontiers Media2021-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/183574Martinez Acosta, Veronica G.; Arellano Carbajal, Fausto; Gillen, Kathy; Tweeten, Kay A.; Zattara, Eduardo Enrique; It Cuts Both Ways: An Annelid Model System for the Study of Regeneration in the Laboratory and in the Classroom; Frontiers Media; Frontiers in Cell and Developmental Biology; 9; 780422; 11-2021; 1-162296-634XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fcell.2021.780422/fullinfo:eu-repo/semantics/altIdentifier/doi/10.3389/fcell.2021.780422info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:25:23Zoai:ri.conicet.gov.ar:11336/183574instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:25:23.826CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv It Cuts Both Ways: An Annelid Model System for the Study of Regeneration in the Laboratory and in the Classroom
title It Cuts Both Ways: An Annelid Model System for the Study of Regeneration in the Laboratory and in the Classroom
spellingShingle It Cuts Both Ways: An Annelid Model System for the Study of Regeneration in the Laboratory and in the Classroom
Martinez Acosta, Veronica G.
CLITELLATE
INVERTEBRATE BIOLOGY
MOLECULAR RESOURCES
NEUROPHYSIOLOGY
STEM CELLS
STEM EDUCATION
title_short It Cuts Both Ways: An Annelid Model System for the Study of Regeneration in the Laboratory and in the Classroom
title_full It Cuts Both Ways: An Annelid Model System for the Study of Regeneration in the Laboratory and in the Classroom
title_fullStr It Cuts Both Ways: An Annelid Model System for the Study of Regeneration in the Laboratory and in the Classroom
title_full_unstemmed It Cuts Both Ways: An Annelid Model System for the Study of Regeneration in the Laboratory and in the Classroom
title_sort It Cuts Both Ways: An Annelid Model System for the Study of Regeneration in the Laboratory and in the Classroom
dc.creator.none.fl_str_mv Martinez Acosta, Veronica G.
Arellano Carbajal, Fausto
Gillen, Kathy
Tweeten, Kay A.
Zattara, Eduardo Enrique
author Martinez Acosta, Veronica G.
author_facet Martinez Acosta, Veronica G.
Arellano Carbajal, Fausto
Gillen, Kathy
Tweeten, Kay A.
Zattara, Eduardo Enrique
author_role author
author2 Arellano Carbajal, Fausto
Gillen, Kathy
Tweeten, Kay A.
Zattara, Eduardo Enrique
author2_role author
author
author
author
dc.subject.none.fl_str_mv CLITELLATE
INVERTEBRATE BIOLOGY
MOLECULAR RESOURCES
NEUROPHYSIOLOGY
STEM CELLS
STEM EDUCATION
topic CLITELLATE
INVERTEBRATE BIOLOGY
MOLECULAR RESOURCES
NEUROPHYSIOLOGY
STEM CELLS
STEM EDUCATION
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The mechanisms supporting regeneration and successful recovery of function have fascinated scientists and the general public for quite some time, with the earliest description of regeneration occurring in the 8th century BC through the Greek mythological story of Prometheus. While most animals demonstrate the capacity for wound-healing, the ability to initiate a developmental process that leads to a partial or complete replacement of a lost structure varies widely among animal taxa. Variation also occurs within single species based on the nature and location of the wound and the developmental stage or age of the individual. Comparative studies of cellular and molecular changes that occur both during, and following, wound healing may point to conserved genomic pathways among animals of different regenerative capacity. Such insights could revolutionize studies within the field of regenerative medicine. In this review, we focus on several closely related species of Lumbriculus (Clitellata: Lumbriculidae), as we present a case for revisiting the use of an annelid model system for the study of regeneration. We hope that this review will provide a primer to Lumbriculus biology not only for regeneration researchers but also for STEM teachers and their students.
Fil: Martinez Acosta, Veronica G.. University Of The Incarnate Word; Estados Unidos
Fil: Arellano Carbajal, Fausto. Universidad Autonoma de Queretaro.; México
Fil: Gillen, Kathy. Kenyon College; Estados Unidos
Fil: Tweeten, Kay A.. St. Catherine University; Estados Unidos
Fil: Zattara, Eduardo Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigaciones en Biodiversidad y Medioambiente. Universidad Nacional del Comahue. Centro Regional Universidad Bariloche. Instituto de Investigaciones en Biodiversidad y Medioambiente; Argentina. Indiana University; Estados Unidos. National Museum Of Natural History. Departamento de Zoología. Area de Invertebrados; Estados Unidos
description The mechanisms supporting regeneration and successful recovery of function have fascinated scientists and the general public for quite some time, with the earliest description of regeneration occurring in the 8th century BC through the Greek mythological story of Prometheus. While most animals demonstrate the capacity for wound-healing, the ability to initiate a developmental process that leads to a partial or complete replacement of a lost structure varies widely among animal taxa. Variation also occurs within single species based on the nature and location of the wound and the developmental stage or age of the individual. Comparative studies of cellular and molecular changes that occur both during, and following, wound healing may point to conserved genomic pathways among animals of different regenerative capacity. Such insights could revolutionize studies within the field of regenerative medicine. In this review, we focus on several closely related species of Lumbriculus (Clitellata: Lumbriculidae), as we present a case for revisiting the use of an annelid model system for the study of regeneration. We hope that this review will provide a primer to Lumbriculus biology not only for regeneration researchers but also for STEM teachers and their students.
publishDate 2021
dc.date.none.fl_str_mv 2021-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/183574
Martinez Acosta, Veronica G.; Arellano Carbajal, Fausto; Gillen, Kathy; Tweeten, Kay A.; Zattara, Eduardo Enrique; It Cuts Both Ways: An Annelid Model System for the Study of Regeneration in the Laboratory and in the Classroom; Frontiers Media; Frontiers in Cell and Developmental Biology; 9; 780422; 11-2021; 1-16
2296-634X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/183574
identifier_str_mv Martinez Acosta, Veronica G.; Arellano Carbajal, Fausto; Gillen, Kathy; Tweeten, Kay A.; Zattara, Eduardo Enrique; It Cuts Both Ways: An Annelid Model System for the Study of Regeneration in the Laboratory and in the Classroom; Frontiers Media; Frontiers in Cell and Developmental Biology; 9; 780422; 11-2021; 1-16
2296-634X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fcell.2021.780422/full
info:eu-repo/semantics/altIdentifier/doi/10.3389/fcell.2021.780422
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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