Determinations of gas–liquid partition coefficients using capillary chromatographic columns. Alkanols in squalane

Autores
Tascon, Marcos; Romero, Lilian M.; Acquaviva, Agustín; Keunchkarian, Sonia; Castells, Cecilia Beatriz Marta
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
This study focused on an investigation into the experimental quantities inherent in the determination of partition coefficients from gas–liquid chromatographic measurements through the use of capillary columns.Wepreparedseveral squalane – (2,6,10,15,19,23-hexamethyltetracosane) – containing columns with very precisely known phase ratios and determined solute retention and hold-up times at 30, 40, 50 and 60 ◦C. We calculated infinite dilution partition coefficients from the slopes of the linear regression of retention factors as a function of the reciprocal of the phase ratio by means of fundamental chromatographic equations. In order to minimize gas–solid and liquid–solid interface contributions to retention, the surface of the capillary inner wall was pretreated to guarantee a uniform coat of stationary phase. The validity of the proposed approach was first tested by estimating the partition coefficients of n-alkanes between n-pentane and n-nonane, for which compounds data from the literature were available. Then partition coefficients of sixteen aliphatic alcohols in squalane were determined at those four temperatures. We deliberately chose these highly challenging systems: alcohols in the reference paraf- finic stationary phase. These solutes exhibited adsorption in the gas–liquid interface that contributed to retention. The corresponding adsorption constant values were estimated.We fully discuss here the uncertainties associated with each experimental measurement and how these fundamental determinations can be performed precisely by circumventing the main drawbacks. The proposed strategy is reliable andmuchsimpler thanthe classical chromatographicmethod employing packed columns.
Fil: Tascon, Marcos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Tecnología de Pinturas (i); Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; Argentina
Fil: Romero, Lilian M.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Tecnología de Pinturas (i); Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; Argentina
Fil: Acquaviva, Agustín. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Tecnología de Pinturas (i); Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; Argentina
Fil: Keunchkarian, Sonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Tecnología de Pinturas (i); Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; Argentina
Fil: Castells, Cecilia Beatriz Marta. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Tecnología de Pinturas (i); Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; Argentina
Materia
Gasliquid Partition Coefficients
Squalane
Alkanols
Capillary Columns
Interfacial Adsorption
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/11175
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/11175
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Determinations of gas–liquid partition coefficients using capillary chromatographic columns. Alkanols in squalaneTascon, MarcosRomero, Lilian M.Acquaviva, AgustínKeunchkarian, SoniaCastells, Cecilia Beatriz MartaGasliquid Partition CoefficientsSqualaneAlkanolsCapillary ColumnsInterfacial Adsorptionhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1This study focused on an investigation into the experimental quantities inherent in the determination of partition coefficients from gas–liquid chromatographic measurements through the use of capillary columns.Wepreparedseveral squalane – (2,6,10,15,19,23-hexamethyltetracosane) – containing columns with very precisely known phase ratios and determined solute retention and hold-up times at 30, 40, 50 and 60 ◦C. We calculated infinite dilution partition coefficients from the slopes of the linear regression of retention factors as a function of the reciprocal of the phase ratio by means of fundamental chromatographic equations. In order to minimize gas–solid and liquid–solid interface contributions to retention, the surface of the capillary inner wall was pretreated to guarantee a uniform coat of stationary phase. The validity of the proposed approach was first tested by estimating the partition coefficients of n-alkanes between n-pentane and n-nonane, for which compounds data from the literature were available. Then partition coefficients of sixteen aliphatic alcohols in squalane were determined at those four temperatures. We deliberately chose these highly challenging systems: alcohols in the reference paraf- finic stationary phase. These solutes exhibited adsorption in the gas–liquid interface that contributed to retention. The corresponding adsorption constant values were estimated.We fully discuss here the uncertainties associated with each experimental measurement and how these fundamental determinations can be performed precisely by circumventing the main drawbacks. The proposed strategy is reliable andmuchsimpler thanthe classical chromatographicmethod employing packed columns.Fil: Tascon, Marcos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Tecnología de Pinturas (i); Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; ArgentinaFil: Romero, Lilian M.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Tecnología de Pinturas (i); Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; ArgentinaFil: Acquaviva, Agustín. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Tecnología de Pinturas (i); Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; ArgentinaFil: Keunchkarian, Sonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Tecnología de Pinturas (i); Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; ArgentinaFil: Castells, Cecilia Beatriz Marta. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Tecnología de Pinturas (i); Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; ArgentinaElsevier Science2013-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/11175Tascon, Marcos; Romero, Lilian M.; Acquaviva, Agustín; Keunchkarian, Sonia; Castells, Cecilia Beatriz Marta; Determinations of gas–liquid partition coefficients using capillary chromatographic columns. Alkanols in squalane; Elsevier Science; Journal Of Chromatography - A; 1294; 6-2013; 130-1360021-9673enginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.chroma.2013.04.032info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0021967313006298info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:01:26Zoai:ri.conicet.gov.ar:11336/11175instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:01:26.416CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Determinations of gas–liquid partition coefficients using capillary chromatographic columns. Alkanols in squalane
title Determinations of gas–liquid partition coefficients using capillary chromatographic columns. Alkanols in squalane
spellingShingle Determinations of gas–liquid partition coefficients using capillary chromatographic columns. Alkanols in squalane
Tascon, Marcos
Gasliquid Partition Coefficients
Squalane
Alkanols
Capillary Columns
Interfacial Adsorption
title_short Determinations of gas–liquid partition coefficients using capillary chromatographic columns. Alkanols in squalane
title_full Determinations of gas–liquid partition coefficients using capillary chromatographic columns. Alkanols in squalane
title_fullStr Determinations of gas–liquid partition coefficients using capillary chromatographic columns. Alkanols in squalane
title_full_unstemmed Determinations of gas–liquid partition coefficients using capillary chromatographic columns. Alkanols in squalane
title_sort Determinations of gas–liquid partition coefficients using capillary chromatographic columns. Alkanols in squalane
dc.creator.none.fl_str_mv Tascon, Marcos
Romero, Lilian M.
Acquaviva, Agustín
Keunchkarian, Sonia
Castells, Cecilia Beatriz Marta
author Tascon, Marcos
author_facet Tascon, Marcos
Romero, Lilian M.
Acquaviva, Agustín
Keunchkarian, Sonia
Castells, Cecilia Beatriz Marta
author_role author
author2 Romero, Lilian M.
Acquaviva, Agustín
Keunchkarian, Sonia
Castells, Cecilia Beatriz Marta
author2_role author
author
author
author
dc.subject.none.fl_str_mv Gasliquid Partition Coefficients
Squalane
Alkanols
Capillary Columns
Interfacial Adsorption
topic Gasliquid Partition Coefficients
Squalane
Alkanols
Capillary Columns
Interfacial Adsorption
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv This study focused on an investigation into the experimental quantities inherent in the determination of partition coefficients from gas–liquid chromatographic measurements through the use of capillary columns.Wepreparedseveral squalane – (2,6,10,15,19,23-hexamethyltetracosane) – containing columns with very precisely known phase ratios and determined solute retention and hold-up times at 30, 40, 50 and 60 ◦C. We calculated infinite dilution partition coefficients from the slopes of the linear regression of retention factors as a function of the reciprocal of the phase ratio by means of fundamental chromatographic equations. In order to minimize gas–solid and liquid–solid interface contributions to retention, the surface of the capillary inner wall was pretreated to guarantee a uniform coat of stationary phase. The validity of the proposed approach was first tested by estimating the partition coefficients of n-alkanes between n-pentane and n-nonane, for which compounds data from the literature were available. Then partition coefficients of sixteen aliphatic alcohols in squalane were determined at those four temperatures. We deliberately chose these highly challenging systems: alcohols in the reference paraf- finic stationary phase. These solutes exhibited adsorption in the gas–liquid interface that contributed to retention. The corresponding adsorption constant values were estimated.We fully discuss here the uncertainties associated with each experimental measurement and how these fundamental determinations can be performed precisely by circumventing the main drawbacks. The proposed strategy is reliable andmuchsimpler thanthe classical chromatographicmethod employing packed columns.
Fil: Tascon, Marcos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Tecnología de Pinturas (i); Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; Argentina
Fil: Romero, Lilian M.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Tecnología de Pinturas (i); Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; Argentina
Fil: Acquaviva, Agustín. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Tecnología de Pinturas (i); Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; Argentina
Fil: Keunchkarian, Sonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Tecnología de Pinturas (i); Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; Argentina
Fil: Castells, Cecilia Beatriz Marta. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Tecnología de Pinturas (i); Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; Argentina
description This study focused on an investigation into the experimental quantities inherent in the determination of partition coefficients from gas–liquid chromatographic measurements through the use of capillary columns.Wepreparedseveral squalane – (2,6,10,15,19,23-hexamethyltetracosane) – containing columns with very precisely known phase ratios and determined solute retention and hold-up times at 30, 40, 50 and 60 ◦C. We calculated infinite dilution partition coefficients from the slopes of the linear regression of retention factors as a function of the reciprocal of the phase ratio by means of fundamental chromatographic equations. In order to minimize gas–solid and liquid–solid interface contributions to retention, the surface of the capillary inner wall was pretreated to guarantee a uniform coat of stationary phase. The validity of the proposed approach was first tested by estimating the partition coefficients of n-alkanes between n-pentane and n-nonane, for which compounds data from the literature were available. Then partition coefficients of sixteen aliphatic alcohols in squalane were determined at those four temperatures. We deliberately chose these highly challenging systems: alcohols in the reference paraf- finic stationary phase. These solutes exhibited adsorption in the gas–liquid interface that contributed to retention. The corresponding adsorption constant values were estimated.We fully discuss here the uncertainties associated with each experimental measurement and how these fundamental determinations can be performed precisely by circumventing the main drawbacks. The proposed strategy is reliable andmuchsimpler thanthe classical chromatographicmethod employing packed columns.
publishDate 2013
dc.date.none.fl_str_mv 2013-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/11175
Tascon, Marcos; Romero, Lilian M.; Acquaviva, Agustín; Keunchkarian, Sonia; Castells, Cecilia Beatriz Marta; Determinations of gas–liquid partition coefficients using capillary chromatographic columns. Alkanols in squalane; Elsevier Science; Journal Of Chromatography - A; 1294; 6-2013; 130-136
0021-9673
url http://hdl.handle.net/11336/11175
identifier_str_mv Tascon, Marcos; Romero, Lilian M.; Acquaviva, Agustín; Keunchkarian, Sonia; Castells, Cecilia Beatriz Marta; Determinations of gas–liquid partition coefficients using capillary chromatographic columns. Alkanols in squalane; Elsevier Science; Journal Of Chromatography - A; 1294; 6-2013; 130-136
0021-9673
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.chroma.2013.04.032
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0021967313006298
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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