C-reactive protein, platelets, and patent ductus arteriosus

Autores
Meinarde, Leonardo; Hillman, Macarena; Rizzotti, Alina; Basquiera, Ana Lisa; Tabares, Aldo; Cuestas, Eduardo
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The association between inflammation, platelets, and patent ductus arteriosus (PDA) has not been studied so far. The purpose of this study was to evaluate whether C-reactive protein (CRP) is related to low platelet count and PDA. This was a retrospective study of 88 infants with a birth weight ≤1500 g and a gestational age ≤30 weeks. Platelet count, CRP, and an echocardiogram were assessed in all infants. The subjects were matched by sex, gestational age, and birth weight. Differences were compared using the χ2, t-test, or Mann–Whitney U-test, as appropriate. Significant variables were entered into a logistic regression model. The association between CRP and platelets was evaluated by correlation and regression analysis. Platelet count (167 000 vs. 213 000 µl−1, p = 0.015) was lower and the CRP (0.45 vs. 0.20 mg/dl, p = 0.002) was higher, and the platelet count correlated inversely with CRP (r = −0.145, p = 0.049) in the infants with vs. without PDA. Only CRP was independently associated with PDA in a logistic regression model (OR 64.1, 95% confidence interval 1.4–2941, p = 0.033).
Fil: Meinarde, Leonardo. Instituto Universitario de Ciencias Biomédicas de Córdoba; Argentina
Fil: Hillman, Macarena. Instituto Universitario de Ciencias Biomédicas de Córdoba; Argentina
Fil: Rizzotti, Alina. Instituto Universitario de Ciencias Biomédicas de Córdoba; Argentina
Fil: Basquiera, Ana Lisa. Instituto Universitario de Ciencias Biomédicas de Córdoba; Argentina
Fil: Tabares, Aldo. Hospital Privado Centro Medico de Córdoba; Argentina
Fil: Cuestas, Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina
Materia
C-Reactive Protein
Patent Ductus Arteriosus
Platelets
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/58075
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling C-reactive protein, platelets, and patent ductus arteriosusMeinarde, LeonardoHillman, MacarenaRizzotti, AlinaBasquiera, Ana LisaTabares, AldoCuestas, EduardoC-Reactive ProteinPatent Ductus ArteriosusPlateletshttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3The association between inflammation, platelets, and patent ductus arteriosus (PDA) has not been studied so far. The purpose of this study was to evaluate whether C-reactive protein (CRP) is related to low platelet count and PDA. This was a retrospective study of 88 infants with a birth weight ≤1500 g and a gestational age ≤30 weeks. Platelet count, CRP, and an echocardiogram were assessed in all infants. The subjects were matched by sex, gestational age, and birth weight. Differences were compared using the χ2, t-test, or Mann–Whitney U-test, as appropriate. Significant variables were entered into a logistic regression model. The association between CRP and platelets was evaluated by correlation and regression analysis. Platelet count (167 000 vs. 213 000 µl−1, p = 0.015) was lower and the CRP (0.45 vs. 0.20 mg/dl, p = 0.002) was higher, and the platelet count correlated inversely with CRP (r = −0.145, p = 0.049) in the infants with vs. without PDA. Only CRP was independently associated with PDA in a logistic regression model (OR 64.1, 95% confidence interval 1.4–2941, p = 0.033).Fil: Meinarde, Leonardo. Instituto Universitario de Ciencias Biomédicas de Córdoba; ArgentinaFil: Hillman, Macarena. Instituto Universitario de Ciencias Biomédicas de Córdoba; ArgentinaFil: Rizzotti, Alina. Instituto Universitario de Ciencias Biomédicas de Córdoba; ArgentinaFil: Basquiera, Ana Lisa. Instituto Universitario de Ciencias Biomédicas de Córdoba; ArgentinaFil: Tabares, Aldo. Hospital Privado Centro Medico de Córdoba; ArgentinaFil: Cuestas, Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaTaylor & Francis Ltd2016-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/58075Meinarde, Leonardo; Hillman, Macarena; Rizzotti, Alina; Basquiera, Ana Lisa; Tabares, Aldo; et al.; C-reactive protein, platelets, and patent ductus arteriosus; Taylor & Francis Ltd; Platelets; 27; 8; 11-2016; 821-8230953-71041369-1635CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1080/09537104.2016.1203398info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/full/10.1080/09537104.2016.1203398info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:46:43Zoai:ri.conicet.gov.ar:11336/58075instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:46:43.578CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv C-reactive protein, platelets, and patent ductus arteriosus
title C-reactive protein, platelets, and patent ductus arteriosus
spellingShingle C-reactive protein, platelets, and patent ductus arteriosus
Meinarde, Leonardo
C-Reactive Protein
Patent Ductus Arteriosus
Platelets
title_short C-reactive protein, platelets, and patent ductus arteriosus
title_full C-reactive protein, platelets, and patent ductus arteriosus
title_fullStr C-reactive protein, platelets, and patent ductus arteriosus
title_full_unstemmed C-reactive protein, platelets, and patent ductus arteriosus
title_sort C-reactive protein, platelets, and patent ductus arteriosus
dc.creator.none.fl_str_mv Meinarde, Leonardo
Hillman, Macarena
Rizzotti, Alina
Basquiera, Ana Lisa
Tabares, Aldo
Cuestas, Eduardo
author Meinarde, Leonardo
author_facet Meinarde, Leonardo
Hillman, Macarena
Rizzotti, Alina
Basquiera, Ana Lisa
Tabares, Aldo
Cuestas, Eduardo
author_role author
author2 Hillman, Macarena
Rizzotti, Alina
Basquiera, Ana Lisa
Tabares, Aldo
Cuestas, Eduardo
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv C-Reactive Protein
Patent Ductus Arteriosus
Platelets
topic C-Reactive Protein
Patent Ductus Arteriosus
Platelets
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The association between inflammation, platelets, and patent ductus arteriosus (PDA) has not been studied so far. The purpose of this study was to evaluate whether C-reactive protein (CRP) is related to low platelet count and PDA. This was a retrospective study of 88 infants with a birth weight ≤1500 g and a gestational age ≤30 weeks. Platelet count, CRP, and an echocardiogram were assessed in all infants. The subjects were matched by sex, gestational age, and birth weight. Differences were compared using the χ2, t-test, or Mann–Whitney U-test, as appropriate. Significant variables were entered into a logistic regression model. The association between CRP and platelets was evaluated by correlation and regression analysis. Platelet count (167 000 vs. 213 000 µl−1, p = 0.015) was lower and the CRP (0.45 vs. 0.20 mg/dl, p = 0.002) was higher, and the platelet count correlated inversely with CRP (r = −0.145, p = 0.049) in the infants with vs. without PDA. Only CRP was independently associated with PDA in a logistic regression model (OR 64.1, 95% confidence interval 1.4–2941, p = 0.033).
Fil: Meinarde, Leonardo. Instituto Universitario de Ciencias Biomédicas de Córdoba; Argentina
Fil: Hillman, Macarena. Instituto Universitario de Ciencias Biomédicas de Córdoba; Argentina
Fil: Rizzotti, Alina. Instituto Universitario de Ciencias Biomédicas de Córdoba; Argentina
Fil: Basquiera, Ana Lisa. Instituto Universitario de Ciencias Biomédicas de Córdoba; Argentina
Fil: Tabares, Aldo. Hospital Privado Centro Medico de Córdoba; Argentina
Fil: Cuestas, Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina
description The association between inflammation, platelets, and patent ductus arteriosus (PDA) has not been studied so far. The purpose of this study was to evaluate whether C-reactive protein (CRP) is related to low platelet count and PDA. This was a retrospective study of 88 infants with a birth weight ≤1500 g and a gestational age ≤30 weeks. Platelet count, CRP, and an echocardiogram were assessed in all infants. The subjects were matched by sex, gestational age, and birth weight. Differences were compared using the χ2, t-test, or Mann–Whitney U-test, as appropriate. Significant variables were entered into a logistic regression model. The association between CRP and platelets was evaluated by correlation and regression analysis. Platelet count (167 000 vs. 213 000 µl−1, p = 0.015) was lower and the CRP (0.45 vs. 0.20 mg/dl, p = 0.002) was higher, and the platelet count correlated inversely with CRP (r = −0.145, p = 0.049) in the infants with vs. without PDA. Only CRP was independently associated with PDA in a logistic regression model (OR 64.1, 95% confidence interval 1.4–2941, p = 0.033).
publishDate 2016
dc.date.none.fl_str_mv 2016-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/58075
Meinarde, Leonardo; Hillman, Macarena; Rizzotti, Alina; Basquiera, Ana Lisa; Tabares, Aldo; et al.; C-reactive protein, platelets, and patent ductus arteriosus; Taylor & Francis Ltd; Platelets; 27; 8; 11-2016; 821-823
0953-7104
1369-1635
CONICET Digital
CONICET
url http://hdl.handle.net/11336/58075
identifier_str_mv Meinarde, Leonardo; Hillman, Macarena; Rizzotti, Alina; Basquiera, Ana Lisa; Tabares, Aldo; et al.; C-reactive protein, platelets, and patent ductus arteriosus; Taylor & Francis Ltd; Platelets; 27; 8; 11-2016; 821-823
0953-7104
1369-1635
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1080/09537104.2016.1203398
info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/full/10.1080/09537104.2016.1203398
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Taylor & Francis Ltd
publisher.none.fl_str_mv Taylor & Francis Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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