Heritability of human cranial dimensions: Comparing the evolvability of different cranial regions
- Autores
- Martínez-Abadías, Neus; Esparza, Mireia; Sjøvold, Torstein; González José, Rolando; Santos, Mauro; Hernández, Miquel
- Año de publicación
- 2009
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Quantitative craniometrical traits have been successfully incorporated into population genetic methods to provide insight into human population structure. However, little is known about the degree of genetic and non-genetic influences on the phenotypic expression of functionally based traits. Many studies have assessed the heritability of craniofacial traits, but complex patterns of correlation among traits have been disregarded. This is a pitfall as the human skull is strongly integrated. Here we reconsider the evolutionary potential of craniometric traits by assessing their heritability values as well as their patterns of genetic and phenotypic correlation using a large pedigree-structured skull series from Hallstatt (Austria). The sample includes 355 complete adult skulls that have been analysed using 3D geometric morphometric techniques. Heritability estimates for 58 cranial linear distances were computed using maximum likelihood methods. These distances were assigned to the main functional and developmental regions of the skull. Results showed that the human skull has substantial amounts of genetic variation, and a t-test showed that there are no statistically significant differences among the heritabilities of facial, neurocranial and basal dimensions. However, skull evolvability is limited by complex patterns of genetic correlation. Phenotypic and genetic patterns of correlation are consistent but do not support traditional hypotheses of integration of the human shape, showing that the classification between brachy- and dolicephalic skulls is not grounded on the genetic level. Here we support previous findings in the mouse cranium and provide empirical evidence that covariation between the maximum widths of the main developmental regions of the skull is the dominant factor of integration in the human skull.
Fil: Martínez-Abadías, Neus. Universidad de Barcelona; España
Fil: Esparza, Mireia. Universidad de Barcelona; España
Fil: Sjøvold, Torstein. Stockholms Universitet; Suecia
Fil: González José, Rolando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; Argentina
Fil: Santos, Mauro. Universitat Autònoma de Barcelona; España
Fil: Hernández, Miquel. Universidad de Barcelona; España - Materia
-
EVOLVABILITY
HERITABILITY
HUMAN SKULL
QUANTITATIVE GENETICS - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/94588
Ver los metadatos del registro completo
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Heritability of human cranial dimensions: Comparing the evolvability of different cranial regionsMartínez-Abadías, NeusEsparza, MireiaSjøvold, TorsteinGonzález José, RolandoSantos, MauroHernández, MiquelEVOLVABILITYHERITABILITYHUMAN SKULLQUANTITATIVE GENETICShttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Quantitative craniometrical traits have been successfully incorporated into population genetic methods to provide insight into human population structure. However, little is known about the degree of genetic and non-genetic influences on the phenotypic expression of functionally based traits. Many studies have assessed the heritability of craniofacial traits, but complex patterns of correlation among traits have been disregarded. This is a pitfall as the human skull is strongly integrated. Here we reconsider the evolutionary potential of craniometric traits by assessing their heritability values as well as their patterns of genetic and phenotypic correlation using a large pedigree-structured skull series from Hallstatt (Austria). The sample includes 355 complete adult skulls that have been analysed using 3D geometric morphometric techniques. Heritability estimates for 58 cranial linear distances were computed using maximum likelihood methods. These distances were assigned to the main functional and developmental regions of the skull. Results showed that the human skull has substantial amounts of genetic variation, and a t-test showed that there are no statistically significant differences among the heritabilities of facial, neurocranial and basal dimensions. However, skull evolvability is limited by complex patterns of genetic correlation. Phenotypic and genetic patterns of correlation are consistent but do not support traditional hypotheses of integration of the human shape, showing that the classification between brachy- and dolicephalic skulls is not grounded on the genetic level. Here we support previous findings in the mouse cranium and provide empirical evidence that covariation between the maximum widths of the main developmental regions of the skull is the dominant factor of integration in the human skull.Fil: Martínez-Abadías, Neus. Universidad de Barcelona; EspañaFil: Esparza, Mireia. Universidad de Barcelona; EspañaFil: Sjøvold, Torstein. Stockholms Universitet; SueciaFil: González José, Rolando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; ArgentinaFil: Santos, Mauro. Universitat Autònoma de Barcelona; EspañaFil: Hernández, Miquel. Universidad de Barcelona; EspañaWiley Blackwell Publishing, Inc2009-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/94588Martínez-Abadías, Neus; Esparza, Mireia; Sjøvold, Torstein; González José, Rolando; Santos, Mauro; et al.; Heritability of human cranial dimensions: Comparing the evolvability of different cranial regions; Wiley Blackwell Publishing, Inc; Journal of Anatomy; 214; 1; 12-2009; 19-350021-8782CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1111/j.1469-7580.2008.01015.xinfo:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/full/10.1111/j.1469-7580.2008.01015.xinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:00:39Zoai:ri.conicet.gov.ar:11336/94588instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:00:39.9CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Heritability of human cranial dimensions: Comparing the evolvability of different cranial regions |
title |
Heritability of human cranial dimensions: Comparing the evolvability of different cranial regions |
spellingShingle |
Heritability of human cranial dimensions: Comparing the evolvability of different cranial regions Martínez-Abadías, Neus EVOLVABILITY HERITABILITY HUMAN SKULL QUANTITATIVE GENETICS |
title_short |
Heritability of human cranial dimensions: Comparing the evolvability of different cranial regions |
title_full |
Heritability of human cranial dimensions: Comparing the evolvability of different cranial regions |
title_fullStr |
Heritability of human cranial dimensions: Comparing the evolvability of different cranial regions |
title_full_unstemmed |
Heritability of human cranial dimensions: Comparing the evolvability of different cranial regions |
title_sort |
Heritability of human cranial dimensions: Comparing the evolvability of different cranial regions |
dc.creator.none.fl_str_mv |
Martínez-Abadías, Neus Esparza, Mireia Sjøvold, Torstein González José, Rolando Santos, Mauro Hernández, Miquel |
author |
Martínez-Abadías, Neus |
author_facet |
Martínez-Abadías, Neus Esparza, Mireia Sjøvold, Torstein González José, Rolando Santos, Mauro Hernández, Miquel |
author_role |
author |
author2 |
Esparza, Mireia Sjøvold, Torstein González José, Rolando Santos, Mauro Hernández, Miquel |
author2_role |
author author author author author |
dc.subject.none.fl_str_mv |
EVOLVABILITY HERITABILITY HUMAN SKULL QUANTITATIVE GENETICS |
topic |
EVOLVABILITY HERITABILITY HUMAN SKULL QUANTITATIVE GENETICS |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
dc.description.none.fl_txt_mv |
Quantitative craniometrical traits have been successfully incorporated into population genetic methods to provide insight into human population structure. However, little is known about the degree of genetic and non-genetic influences on the phenotypic expression of functionally based traits. Many studies have assessed the heritability of craniofacial traits, but complex patterns of correlation among traits have been disregarded. This is a pitfall as the human skull is strongly integrated. Here we reconsider the evolutionary potential of craniometric traits by assessing their heritability values as well as their patterns of genetic and phenotypic correlation using a large pedigree-structured skull series from Hallstatt (Austria). The sample includes 355 complete adult skulls that have been analysed using 3D geometric morphometric techniques. Heritability estimates for 58 cranial linear distances were computed using maximum likelihood methods. These distances were assigned to the main functional and developmental regions of the skull. Results showed that the human skull has substantial amounts of genetic variation, and a t-test showed that there are no statistically significant differences among the heritabilities of facial, neurocranial and basal dimensions. However, skull evolvability is limited by complex patterns of genetic correlation. Phenotypic and genetic patterns of correlation are consistent but do not support traditional hypotheses of integration of the human shape, showing that the classification between brachy- and dolicephalic skulls is not grounded on the genetic level. Here we support previous findings in the mouse cranium and provide empirical evidence that covariation between the maximum widths of the main developmental regions of the skull is the dominant factor of integration in the human skull. Fil: Martínez-Abadías, Neus. Universidad de Barcelona; España Fil: Esparza, Mireia. Universidad de Barcelona; España Fil: Sjøvold, Torstein. Stockholms Universitet; Suecia Fil: González José, Rolando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; Argentina Fil: Santos, Mauro. Universitat Autònoma de Barcelona; España Fil: Hernández, Miquel. Universidad de Barcelona; España |
description |
Quantitative craniometrical traits have been successfully incorporated into population genetic methods to provide insight into human population structure. However, little is known about the degree of genetic and non-genetic influences on the phenotypic expression of functionally based traits. Many studies have assessed the heritability of craniofacial traits, but complex patterns of correlation among traits have been disregarded. This is a pitfall as the human skull is strongly integrated. Here we reconsider the evolutionary potential of craniometric traits by assessing their heritability values as well as their patterns of genetic and phenotypic correlation using a large pedigree-structured skull series from Hallstatt (Austria). The sample includes 355 complete adult skulls that have been analysed using 3D geometric morphometric techniques. Heritability estimates for 58 cranial linear distances were computed using maximum likelihood methods. These distances were assigned to the main functional and developmental regions of the skull. Results showed that the human skull has substantial amounts of genetic variation, and a t-test showed that there are no statistically significant differences among the heritabilities of facial, neurocranial and basal dimensions. However, skull evolvability is limited by complex patterns of genetic correlation. Phenotypic and genetic patterns of correlation are consistent but do not support traditional hypotheses of integration of the human shape, showing that the classification between brachy- and dolicephalic skulls is not grounded on the genetic level. Here we support previous findings in the mouse cranium and provide empirical evidence that covariation between the maximum widths of the main developmental regions of the skull is the dominant factor of integration in the human skull. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-12 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/94588 Martínez-Abadías, Neus; Esparza, Mireia; Sjøvold, Torstein; González José, Rolando; Santos, Mauro; et al.; Heritability of human cranial dimensions: Comparing the evolvability of different cranial regions; Wiley Blackwell Publishing, Inc; Journal of Anatomy; 214; 1; 12-2009; 19-35 0021-8782 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/94588 |
identifier_str_mv |
Martínez-Abadías, Neus; Esparza, Mireia; Sjøvold, Torstein; González José, Rolando; Santos, Mauro; et al.; Heritability of human cranial dimensions: Comparing the evolvability of different cranial regions; Wiley Blackwell Publishing, Inc; Journal of Anatomy; 214; 1; 12-2009; 19-35 0021-8782 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.1111/j.1469-7580.2008.01015.x info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/full/10.1111/j.1469-7580.2008.01015.x |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Wiley Blackwell Publishing, Inc |
publisher.none.fl_str_mv |
Wiley Blackwell Publishing, Inc |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844613790962810880 |
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13.070432 |