Short communication: Emergence of novel A/G recombinant HIV-1 strains in Argentina

Autores
Fernández, María Florencia; Golemba, Marcelo Darío; Terrones, Carmen; Paradiso, Patricia; Nassif, Juan C.; Bologna, Rosa; Mangano, Andrea María Mercedes; Sen, Luisa; Aulicino, Paula
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The predominant circulating HIV-1 strains in South America are subtype B and B/F recombinants with different distributions among countries. However, the emergence of other subtypes is a matter of concern and needs continuous monitoring. We identified three different A/G recombinants in Argentina, two of them in vertically infected children from unlinked mothers and one in an adult female. HIV-1 pol sequences from the children showed novel A/G recombination patterns and no phylogenetic relationship with previously reported South American A/G sequences. The third A/G recombinant was a CRF06-cpx with African origin. The detection of new or unusual subtypes is important to avoid false-negative PCR HIV-1 early diagnosis due to detection failures and for future vaccine development.
Fil: Fernández, María Florencia. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Golemba, Marcelo Darío. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Terrones, Carmen. Ciudad Autónoma de Buenos Aires. Hospital ‘‘Carlos G. Durand"; Argentina
Fil: Paradiso, Patricia. Ciudad Autónoma de Buenos Aires. Hospital ‘‘Carlos G. Durand"; Argentina
Fil: Nassif, Juan C.. Ciudad Autónoma de Buenos Aires. Hospital ‘‘Carlos G. Durand"; Argentina
Fil: Bologna, Rosa. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría ; Argentina
Fil: Mangano, Andrea María Mercedes. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Sen, Luisa. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Aulicino, Paula. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Hiv Subtypes
Molecular Epidemiology
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/38300
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Short communication: Emergence of novel A/G recombinant HIV-1 strains in ArgentinaFernández, María FlorenciaGolemba, Marcelo DaríoTerrones, CarmenParadiso, PatriciaNassif, Juan C.Bologna, RosaMangano, Andrea María MercedesSen, LuisaAulicino, PaulaHiv SubtypesMolecular Epidemiologyhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The predominant circulating HIV-1 strains in South America are subtype B and B/F recombinants with different distributions among countries. However, the emergence of other subtypes is a matter of concern and needs continuous monitoring. We identified three different A/G recombinants in Argentina, two of them in vertically infected children from unlinked mothers and one in an adult female. HIV-1 pol sequences from the children showed novel A/G recombination patterns and no phylogenetic relationship with previously reported South American A/G sequences. The third A/G recombinant was a CRF06-cpx with African origin. The detection of new or unusual subtypes is important to avoid false-negative PCR HIV-1 early diagnosis due to detection failures and for future vaccine development.Fil: Fernández, María Florencia. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Golemba, Marcelo Darío. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Terrones, Carmen. Ciudad Autónoma de Buenos Aires. Hospital ‘‘Carlos G. Durand"; ArgentinaFil: Paradiso, Patricia. Ciudad Autónoma de Buenos Aires. Hospital ‘‘Carlos G. Durand"; ArgentinaFil: Nassif, Juan C.. Ciudad Autónoma de Buenos Aires. Hospital ‘‘Carlos G. Durand"; ArgentinaFil: Bologna, Rosa. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría ; ArgentinaFil: Mangano, Andrea María Mercedes. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Sen, Luisa. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Aulicino, Paula. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaMary Ann Liebert2015-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/38300Fernández, María Florencia; Golemba, Marcelo Darío; Terrones, Carmen; Paradiso, Patricia; Nassif, Juan C.; et al.; Short communication: Emergence of novel A/G recombinant HIV-1 strains in Argentina; Mary Ann Liebert; Aids Research and Human Retroviruses; 31; 3; 3-2015; 293-2970889-2229CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1089/aid.2014.0196info:eu-repo/semantics/altIdentifier/url/https://www.liebertpub.com/doi/abs/10.1089/aid.2014.0196info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:16:45Zoai:ri.conicet.gov.ar:11336/38300instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:16:46.003CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Short communication: Emergence of novel A/G recombinant HIV-1 strains in Argentina
title Short communication: Emergence of novel A/G recombinant HIV-1 strains in Argentina
spellingShingle Short communication: Emergence of novel A/G recombinant HIV-1 strains in Argentina
Fernández, María Florencia
Hiv Subtypes
Molecular Epidemiology
title_short Short communication: Emergence of novel A/G recombinant HIV-1 strains in Argentina
title_full Short communication: Emergence of novel A/G recombinant HIV-1 strains in Argentina
title_fullStr Short communication: Emergence of novel A/G recombinant HIV-1 strains in Argentina
title_full_unstemmed Short communication: Emergence of novel A/G recombinant HIV-1 strains in Argentina
title_sort Short communication: Emergence of novel A/G recombinant HIV-1 strains in Argentina
dc.creator.none.fl_str_mv Fernández, María Florencia
Golemba, Marcelo Darío
Terrones, Carmen
Paradiso, Patricia
Nassif, Juan C.
Bologna, Rosa
Mangano, Andrea María Mercedes
Sen, Luisa
Aulicino, Paula
author Fernández, María Florencia
author_facet Fernández, María Florencia
Golemba, Marcelo Darío
Terrones, Carmen
Paradiso, Patricia
Nassif, Juan C.
Bologna, Rosa
Mangano, Andrea María Mercedes
Sen, Luisa
Aulicino, Paula
author_role author
author2 Golemba, Marcelo Darío
Terrones, Carmen
Paradiso, Patricia
Nassif, Juan C.
Bologna, Rosa
Mangano, Andrea María Mercedes
Sen, Luisa
Aulicino, Paula
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Hiv Subtypes
Molecular Epidemiology
topic Hiv Subtypes
Molecular Epidemiology
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The predominant circulating HIV-1 strains in South America are subtype B and B/F recombinants with different distributions among countries. However, the emergence of other subtypes is a matter of concern and needs continuous monitoring. We identified three different A/G recombinants in Argentina, two of them in vertically infected children from unlinked mothers and one in an adult female. HIV-1 pol sequences from the children showed novel A/G recombination patterns and no phylogenetic relationship with previously reported South American A/G sequences. The third A/G recombinant was a CRF06-cpx with African origin. The detection of new or unusual subtypes is important to avoid false-negative PCR HIV-1 early diagnosis due to detection failures and for future vaccine development.
Fil: Fernández, María Florencia. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Golemba, Marcelo Darío. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Terrones, Carmen. Ciudad Autónoma de Buenos Aires. Hospital ‘‘Carlos G. Durand"; Argentina
Fil: Paradiso, Patricia. Ciudad Autónoma de Buenos Aires. Hospital ‘‘Carlos G. Durand"; Argentina
Fil: Nassif, Juan C.. Ciudad Autónoma de Buenos Aires. Hospital ‘‘Carlos G. Durand"; Argentina
Fil: Bologna, Rosa. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría ; Argentina
Fil: Mangano, Andrea María Mercedes. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Sen, Luisa. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Aulicino, Paula. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description The predominant circulating HIV-1 strains in South America are subtype B and B/F recombinants with different distributions among countries. However, the emergence of other subtypes is a matter of concern and needs continuous monitoring. We identified three different A/G recombinants in Argentina, two of them in vertically infected children from unlinked mothers and one in an adult female. HIV-1 pol sequences from the children showed novel A/G recombination patterns and no phylogenetic relationship with previously reported South American A/G sequences. The third A/G recombinant was a CRF06-cpx with African origin. The detection of new or unusual subtypes is important to avoid false-negative PCR HIV-1 early diagnosis due to detection failures and for future vaccine development.
publishDate 2015
dc.date.none.fl_str_mv 2015-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/38300
Fernández, María Florencia; Golemba, Marcelo Darío; Terrones, Carmen; Paradiso, Patricia; Nassif, Juan C.; et al.; Short communication: Emergence of novel A/G recombinant HIV-1 strains in Argentina; Mary Ann Liebert; Aids Research and Human Retroviruses; 31; 3; 3-2015; 293-297
0889-2229
CONICET Digital
CONICET
url http://hdl.handle.net/11336/38300
identifier_str_mv Fernández, María Florencia; Golemba, Marcelo Darío; Terrones, Carmen; Paradiso, Patricia; Nassif, Juan C.; et al.; Short communication: Emergence of novel A/G recombinant HIV-1 strains in Argentina; Mary Ann Liebert; Aids Research and Human Retroviruses; 31; 3; 3-2015; 293-297
0889-2229
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1089/aid.2014.0196
info:eu-repo/semantics/altIdentifier/url/https://www.liebertpub.com/doi/abs/10.1089/aid.2014.0196
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Mary Ann Liebert
publisher.none.fl_str_mv Mary Ann Liebert
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842980914348425216
score 12.993085

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