Antiviral activity of plant species from Tierra del Fuego

Autores
Aguilar, J.; Duco, Walter Alejandro; Pleitavino, R.; Konigheim, Brenda Salome; Núñez Montoya, Susana Carolina; Colloca, Cristina Beatriz
Año de publicación
2019
Idioma
inglés
Tipo de recurso
documento de conferencia
Estado
versión publicada
Descripción
The search for new antivirals is a constant and current need. Numerous viral infections recognized for a long time in the old world begin to be a health problem for America (Chikungunya, Zika, among others), which do not have available antiviral treatments. In addition, the appearance of strains of other resistant viral pathologies, such as herpes simplex type 1 (HSV-I), is added. In the Island Tierra de Fuego, there is a large number of plant species that have not been studied. They are plants that grow in inhospitable environmental conditions and have designed defence mechanisms that allow them to survive in this type of environment. These characteristics could favour that these species possess bioactive compounds with a wide range of pharmacological activities. In this context, we proposed to evaluate in a preliminary way the cytotoxicity and the in vitro antiviral effect of extracts of native plants of Tierra del Fuego against Chikungunya (CHIKV) and HSV-1 viruses. Specimens of the species Empetrum rubrum Vaht ex Willd were selected. (Empetraceae) uvilla (Er) and Plantago barbata subsp. Austro-Andean Rahn. (Plantaginaceae) murtilla (Pb)
Fil: Aguilar, J.. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; Argentina
Fil: Duco, Walter Alejandro. Universidad Nacional de Tierra del Fuego, Antártida e Islas del Atlántico Sur. Instituto de Ciencias Polares, Recursos Naturales y Ambiente. Departamento de Biología; Argentina
Fil: Pleitavino, R.. Universidad Nacional de Tierra del Fuego, Antártida e Islas del Atlántico Sur. Instituto de Ciencias Polares, Recursos Naturales y Ambiente. Departamento de Biología; Argentina
Fil: Konigheim, Brenda Salome. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Núñez Montoya, Susana Carolina. Universidad Nacional de Tierra del Fuego, Antártida e Islas del Atlántico Sur. Instituto de Ciencias Polares, Recursos Naturales y Ambiente. Departamento de Biología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina
Fil: Colloca, Cristina Beatriz. Universidad Nacional de Tierra del Fuego, Antártida e Islas del Atlántico Sur. Instituto de Ciencias Polares, Recursos Naturales y Ambiente. Departamento de Biología; Argentina
Drug Discovery for Neglected Diseases International Congress 2018
Ciudad Autónoma de Buenos Aires
Argentina
Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica
Materia
Empetrum rubrum
Plantago barbata subsp. Austro-Andean
Chikungunya virus
Zika virus
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/131569
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/131569
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Antiviral activity of plant species from Tierra del FuegoAguilar, J.Duco, Walter AlejandroPleitavino, R.Konigheim, Brenda SalomeNúñez Montoya, Susana CarolinaColloca, Cristina BeatrizEmpetrum rubrumPlantago barbata subsp. Austro-AndeanChikungunya virusZika virushttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The search for new antivirals is a constant and current need. Numerous viral infections recognized for a long time in the old world begin to be a health problem for America (Chikungunya, Zika, among others), which do not have available antiviral treatments. In addition, the appearance of strains of other resistant viral pathologies, such as herpes simplex type 1 (HSV-I), is added. In the Island Tierra de Fuego, there is a large number of plant species that have not been studied. They are plants that grow in inhospitable environmental conditions and have designed defence mechanisms that allow them to survive in this type of environment. These characteristics could favour that these species possess bioactive compounds with a wide range of pharmacological activities. In this context, we proposed to evaluate in a preliminary way the cytotoxicity and the in vitro antiviral effect of extracts of native plants of Tierra del Fuego against Chikungunya (CHIKV) and HSV-1 viruses. Specimens of the species Empetrum rubrum Vaht ex Willd were selected. (Empetraceae) uvilla (Er) and Plantago barbata subsp. Austro-Andean Rahn. (Plantaginaceae) murtilla (Pb)Fil: Aguilar, J.. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; ArgentinaFil: Duco, Walter Alejandro. Universidad Nacional de Tierra del Fuego, Antártida e Islas del Atlántico Sur. Instituto de Ciencias Polares, Recursos Naturales y Ambiente. Departamento de Biología; ArgentinaFil: Pleitavino, R.. Universidad Nacional de Tierra del Fuego, Antártida e Islas del Atlántico Sur. Instituto de Ciencias Polares, Recursos Naturales y Ambiente. Departamento de Biología; ArgentinaFil: Konigheim, Brenda Salome. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Núñez Montoya, Susana Carolina. Universidad Nacional de Tierra del Fuego, Antártida e Islas del Atlántico Sur. Instituto de Ciencias Polares, Recursos Naturales y Ambiente. Departamento de Biología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaFil: Colloca, Cristina Beatriz. Universidad Nacional de Tierra del Fuego, Antártida e Islas del Atlántico Sur. Instituto de Ciencias Polares, Recursos Naturales y Ambiente. Departamento de Biología; ArgentinaDrug Discovery for Neglected Diseases International Congress 2018Ciudad Autónoma de Buenos AiresArgentinaUniversidad de Buenos Aires. Facultad de Farmacia y BioquímicaUniversidad de Buenos AiresMoglioni, Albertina Gladys2019info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectCongresoBookhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/131569Antiviral activity of plant species from Tierra del Fuego; Drug Discovery for Neglected Diseases International Congress 2018; Ciudad Autónoma de Buenos Aires; Argentina; 2018; 239-239978-987-47034-0-8CONICET DigitalCONICETengInternacionalinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:32:08Zoai:ri.conicet.gov.ar:11336/131569instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:32:08.631CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Antiviral activity of plant species from Tierra del Fuego
title Antiviral activity of plant species from Tierra del Fuego
spellingShingle Antiviral activity of plant species from Tierra del Fuego
Aguilar, J.
Empetrum rubrum
Plantago barbata subsp. Austro-Andean
Chikungunya virus
Zika virus
title_short Antiviral activity of plant species from Tierra del Fuego
title_full Antiviral activity of plant species from Tierra del Fuego
title_fullStr Antiviral activity of plant species from Tierra del Fuego
title_full_unstemmed Antiviral activity of plant species from Tierra del Fuego
title_sort Antiviral activity of plant species from Tierra del Fuego
dc.creator.none.fl_str_mv Aguilar, J.
Duco, Walter Alejandro
Pleitavino, R.
Konigheim, Brenda Salome
Núñez Montoya, Susana Carolina
Colloca, Cristina Beatriz
author Aguilar, J.
author_facet Aguilar, J.
Duco, Walter Alejandro
Pleitavino, R.
Konigheim, Brenda Salome
Núñez Montoya, Susana Carolina
Colloca, Cristina Beatriz
author_role author
author2 Duco, Walter Alejandro
Pleitavino, R.
Konigheim, Brenda Salome
Núñez Montoya, Susana Carolina
Colloca, Cristina Beatriz
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Moglioni, Albertina Gladys
dc.subject.none.fl_str_mv Empetrum rubrum
Plantago barbata subsp. Austro-Andean
Chikungunya virus
Zika virus
topic Empetrum rubrum
Plantago barbata subsp. Austro-Andean
Chikungunya virus
Zika virus
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The search for new antivirals is a constant and current need. Numerous viral infections recognized for a long time in the old world begin to be a health problem for America (Chikungunya, Zika, among others), which do not have available antiviral treatments. In addition, the appearance of strains of other resistant viral pathologies, such as herpes simplex type 1 (HSV-I), is added. In the Island Tierra de Fuego, there is a large number of plant species that have not been studied. They are plants that grow in inhospitable environmental conditions and have designed defence mechanisms that allow them to survive in this type of environment. These characteristics could favour that these species possess bioactive compounds with a wide range of pharmacological activities. In this context, we proposed to evaluate in a preliminary way the cytotoxicity and the in vitro antiviral effect of extracts of native plants of Tierra del Fuego against Chikungunya (CHIKV) and HSV-1 viruses. Specimens of the species Empetrum rubrum Vaht ex Willd were selected. (Empetraceae) uvilla (Er) and Plantago barbata subsp. Austro-Andean Rahn. (Plantaginaceae) murtilla (Pb)
Fil: Aguilar, J.. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; Argentina
Fil: Duco, Walter Alejandro. Universidad Nacional de Tierra del Fuego, Antártida e Islas del Atlántico Sur. Instituto de Ciencias Polares, Recursos Naturales y Ambiente. Departamento de Biología; Argentina
Fil: Pleitavino, R.. Universidad Nacional de Tierra del Fuego, Antártida e Islas del Atlántico Sur. Instituto de Ciencias Polares, Recursos Naturales y Ambiente. Departamento de Biología; Argentina
Fil: Konigheim, Brenda Salome. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Núñez Montoya, Susana Carolina. Universidad Nacional de Tierra del Fuego, Antártida e Islas del Atlántico Sur. Instituto de Ciencias Polares, Recursos Naturales y Ambiente. Departamento de Biología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina
Fil: Colloca, Cristina Beatriz. Universidad Nacional de Tierra del Fuego, Antártida e Islas del Atlántico Sur. Instituto de Ciencias Polares, Recursos Naturales y Ambiente. Departamento de Biología; Argentina
Drug Discovery for Neglected Diseases International Congress 2018
Ciudad Autónoma de Buenos Aires
Argentina
Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica
description The search for new antivirals is a constant and current need. Numerous viral infections recognized for a long time in the old world begin to be a health problem for America (Chikungunya, Zika, among others), which do not have available antiviral treatments. In addition, the appearance of strains of other resistant viral pathologies, such as herpes simplex type 1 (HSV-I), is added. In the Island Tierra de Fuego, there is a large number of plant species that have not been studied. They are plants that grow in inhospitable environmental conditions and have designed defence mechanisms that allow them to survive in this type of environment. These characteristics could favour that these species possess bioactive compounds with a wide range of pharmacological activities. In this context, we proposed to evaluate in a preliminary way the cytotoxicity and the in vitro antiviral effect of extracts of native plants of Tierra del Fuego against Chikungunya (CHIKV) and HSV-1 viruses. Specimens of the species Empetrum rubrum Vaht ex Willd were selected. (Empetraceae) uvilla (Er) and Plantago barbata subsp. Austro-Andean Rahn. (Plantaginaceae) murtilla (Pb)
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/conferenceObject
Congreso
Book
http://purl.org/coar/resource_type/c_5794
info:ar-repo/semantics/documentoDeConferencia
status_str publishedVersion
format conferenceObject
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/131569
Antiviral activity of plant species from Tierra del Fuego; Drug Discovery for Neglected Diseases International Congress 2018; Ciudad Autónoma de Buenos Aires; Argentina; 2018; 239-239
978-987-47034-0-8
CONICET Digital
CONICET
url http://hdl.handle.net/11336/131569
identifier_str_mv Antiviral activity of plant species from Tierra del Fuego; Drug Discovery for Neglected Diseases International Congress 2018; Ciudad Autónoma de Buenos Aires; Argentina; 2018; 239-239
978-987-47034-0-8
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.coverage.none.fl_str_mv Internacional
dc.publisher.none.fl_str_mv Universidad de Buenos Aires
publisher.none.fl_str_mv Universidad de Buenos Aires
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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