Improving the purification of hydroxyethyl starch by means of supercritical and near-critical fluid extraction using CO2 and a mixture of CO2-ethanol: A combined experimental and m...

Autores: Piqueras, Cristian Martin; Eberhardt, Andrea Mariel; Vega, Daniel Alberto; Damiani, Daniel Eduardo
Año de publicación: 2014
Idioma: inglés
Tipo de recurso: artículo
Estado: versión publicada
Descripción: The hydroxyethyl starch purification was performed by means of supercritical and near-critical fluid extraction within single-phase conditions using CO2 and a mixture of CO2?ethanol. Hydroxyethyl starch with concentrations of ethylene glycol in the range of 28,000 to 3000 ppm was successfully purified in a single stage. The intraparticle mass transfer was determined through a hot sphere diffusion model. The values of the effective diffusion coefficients, obtained from the model fitted to experimental data, indicate that the hindrance for ethylene glycol extraction is due to mass transfer limitations attributed to the closed pore structure generated during the crystallization of the solid. In the same sense, the strong interaction between the contaminant and the hydroxyethyl starch at specific points of the surface could also be a detrimental factor. We show that, under these working conditions, most of the contamination can be removed, providing a simple process which saves the high consumptions of deionized water employed in the traditional ultrafiltration.
Fil: Piqueras, Cristian Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
Fil: Eberhardt, Andrea Mariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
Fil: Vega, Daniel Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Física del Sur. Universidad Nacional del Sur. Departamento de Física. Instituto de Física del Sur; Argentina
Fil: Damiani, Daniel Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
Materia: Hydroxyethyl Starch
Supercritical Carbon Dioxide
Ethylene Glycol
Purification
Nivel de accesibilidad: acceso abierto
Condiciones de uso: https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
Institución: Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador: oai:ri.conicet.gov.ar:11336/24927

Acceder

id	CONICETDig_447665f304ce0b82d6e5dfa726400d14
oai_identifier_str	oai:ri.conicet.gov.ar:11336/24927
network_acronym_str	CONICETDig
repository_id_str	3498
network_name_str	CONICET Digital (CONICET)
spelling	Improving the purification of hydroxyethyl starch by means of supercritical and near-critical fluid extraction using CO2 and a mixture of CO2-ethanol: A combined experimental and modeling studyPiqueras, Cristian MartinEberhardt, Andrea MarielVega, Daniel AlbertoDamiani, Daniel EduardoHydroxyethyl StarchSupercritical Carbon DioxideEthylene GlycolPurificationhttps://purl.org/becyt/ford/2.4https://purl.org/becyt/ford/2The hydroxyethyl starch purification was performed by means of supercritical and near-critical fluid extraction within single-phase conditions using CO2 and a mixture of CO2?ethanol. Hydroxyethyl starch with concentrations of ethylene glycol in the range of 28,000 to 3000 ppm was successfully purified in a single stage. The intraparticle mass transfer was determined through a hot sphere diffusion model. The values of the effective diffusion coefficients, obtained from the model fitted to experimental data, indicate that the hindrance for ethylene glycol extraction is due to mass transfer limitations attributed to the closed pore structure generated during the crystallization of the solid. In the same sense, the strong interaction between the contaminant and the hydroxyethyl starch at specific points of the surface could also be a detrimental factor. We show that, under these working conditions, most of the contamination can be removed, providing a simple process which saves the high consumptions of deionized water employed in the traditional ultrafiltration.Fil: Piqueras, Cristian Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; ArgentinaFil: Eberhardt, Andrea Mariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; ArgentinaFil: Vega, Daniel Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Física del Sur. Universidad Nacional del Sur. Departamento de Física. Instituto de Física del Sur; ArgentinaFil: Damiani, Daniel Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; ArgentinaElsevier Science2014-11-20info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/24927Piqueras, Cristian Martin; Eberhardt, Andrea Mariel; Vega, Daniel Alberto; Damiani, Daniel Eduardo; Improving the purification of hydroxyethyl starch by means of supercritical and near-critical fluid extraction using CO2 and a mixture of CO2-ethanol: A combined experimental and modeling study; Elsevier Science; Chemical Engineering And Processing; 88; 20-11-2014; 89-980255-2701CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0255270114002499info:eu-repo/semantics/altIdentifier/doi/10.1016/j.cep.2014.11.012info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:42:10Zoai:ri.conicet.gov.ar:11336/24927instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:42:10.627CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv	Improving the purification of hydroxyethyl starch by means of supercritical and near-critical fluid extraction using CO2 and a mixture of CO2-ethanol: A combined experimental and modeling study
title	Improving the purification of hydroxyethyl starch by means of supercritical and near-critical fluid extraction using CO2 and a mixture of CO2-ethanol: A combined experimental and modeling study
spellingShingle	Improving the purification of hydroxyethyl starch by means of supercritical and near-critical fluid extraction using CO2 and a mixture of CO2-ethanol: A combined experimental and modeling study Piqueras, Cristian Martin Hydroxyethyl Starch Supercritical Carbon Dioxide Ethylene Glycol Purification
title_short	Improving the purification of hydroxyethyl starch by means of supercritical and near-critical fluid extraction using CO2 and a mixture of CO2-ethanol: A combined experimental and modeling study
title_full	Improving the purification of hydroxyethyl starch by means of supercritical and near-critical fluid extraction using CO2 and a mixture of CO2-ethanol: A combined experimental and modeling study
title_fullStr	Improving the purification of hydroxyethyl starch by means of supercritical and near-critical fluid extraction using CO2 and a mixture of CO2-ethanol: A combined experimental and modeling study
title_full_unstemmed	Improving the purification of hydroxyethyl starch by means of supercritical and near-critical fluid extraction using CO2 and a mixture of CO2-ethanol: A combined experimental and modeling study
title_sort	Improving the purification of hydroxyethyl starch by means of supercritical and near-critical fluid extraction using CO2 and a mixture of CO2-ethanol: A combined experimental and modeling study
dc.creator.none.fl_str_mv	Piqueras, Cristian Martin Eberhardt, Andrea Mariel Vega, Daniel Alberto Damiani, Daniel Eduardo
author	Piqueras, Cristian Martin
author_facet	Piqueras, Cristian Martin Eberhardt, Andrea Mariel Vega, Daniel Alberto Damiani, Daniel Eduardo
author_role	author
author2	Eberhardt, Andrea Mariel Vega, Daniel Alberto Damiani, Daniel Eduardo
author2_role	author author author
dc.subject.none.fl_str_mv	Hydroxyethyl Starch Supercritical Carbon Dioxide Ethylene Glycol Purification
topic	Hydroxyethyl Starch Supercritical Carbon Dioxide Ethylene Glycol Purification
purl_subject.fl_str_mv	https://purl.org/becyt/ford/2.4 https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv	The hydroxyethyl starch purification was performed by means of supercritical and near-critical fluid extraction within single-phase conditions using CO2 and a mixture of CO2?ethanol. Hydroxyethyl starch with concentrations of ethylene glycol in the range of 28,000 to 3000 ppm was successfully purified in a single stage. The intraparticle mass transfer was determined through a hot sphere diffusion model. The values of the effective diffusion coefficients, obtained from the model fitted to experimental data, indicate that the hindrance for ethylene glycol extraction is due to mass transfer limitations attributed to the closed pore structure generated during the crystallization of the solid. In the same sense, the strong interaction between the contaminant and the hydroxyethyl starch at specific points of the surface could also be a detrimental factor. We show that, under these working conditions, most of the contamination can be removed, providing a simple process which saves the high consumptions of deionized water employed in the traditional ultrafiltration. Fil: Piqueras, Cristian Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina Fil: Eberhardt, Andrea Mariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina Fil: Vega, Daniel Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Física del Sur. Universidad Nacional del Sur. Departamento de Física. Instituto de Física del Sur; Argentina Fil: Damiani, Daniel Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
description	The hydroxyethyl starch purification was performed by means of supercritical and near-critical fluid extraction within single-phase conditions using CO2 and a mixture of CO2?ethanol. Hydroxyethyl starch with concentrations of ethylene glycol in the range of 28,000 to 3000 ppm was successfully purified in a single stage. The intraparticle mass transfer was determined through a hot sphere diffusion model. The values of the effective diffusion coefficients, obtained from the model fitted to experimental data, indicate that the hindrance for ethylene glycol extraction is due to mass transfer limitations attributed to the closed pore structure generated during the crystallization of the solid. In the same sense, the strong interaction between the contaminant and the hydroxyethyl starch at specific points of the surface could also be a detrimental factor. We show that, under these working conditions, most of the contamination can be removed, providing a simple process which saves the high consumptions of deionized water employed in the traditional ultrafiltration.
publishDate	2014
dc.date.none.fl_str_mv	2014-11-20
dc.type.none.fl_str_mv	info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo
format	article
status_str	publishedVersion
dc.identifier.none.fl_str_mv	http://hdl.handle.net/11336/24927 Piqueras, Cristian Martin; Eberhardt, Andrea Mariel; Vega, Daniel Alberto; Damiani, Daniel Eduardo; Improving the purification of hydroxyethyl starch by means of supercritical and near-critical fluid extraction using CO2 and a mixture of CO2-ethanol: A combined experimental and modeling study; Elsevier Science; Chemical Engineering And Processing; 88; 20-11-2014; 89-98 0255-2701 CONICET Digital CONICET
url	http://hdl.handle.net/11336/24927
identifier_str_mv	Piqueras, Cristian Martin; Eberhardt, Andrea Mariel; Vega, Daniel Alberto; Damiani, Daniel Eduardo; Improving the purification of hydroxyethyl starch by means of supercritical and near-critical fluid extraction using CO2 and a mixture of CO2-ethanol: A combined experimental and modeling study; Elsevier Science; Chemical Engineering And Processing; 88; 20-11-2014; 89-98 0255-2701 CONICET Digital CONICET
dc.language.none.fl_str_mv	eng
language	eng
dc.relation.none.fl_str_mv	info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0255270114002499 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.cep.2014.11.012
dc.rights.none.fl_str_mv	info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv	openAccess
rights_invalid_str_mv	https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv	application/pdf application/pdf application/pdf application/pdf
dc.publisher.none.fl_str_mv	Elsevier Science
publisher.none.fl_str_mv	Elsevier Science
dc.source.none.fl_str_mv	reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str	CONICET Digital (CONICET)
collection	CONICET Digital (CONICET)
instname_str	Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv	CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv	dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_	1844614454183985152
score	13.070432

Improving the purification of hydroxyethyl starch by means of supercritical and near-critical fluid extraction using CO2 and a mixture of CO2-ethanol: A combined experimental and m...

Publicaciones similares