Phenotypic Characteristics of Hyperacusis in Tinnitus

Autores
Schecklmann, Martin; Landgraebe, Michael; Langguth, Berthold; Elgoyhen, Ana Belen; Tinnitus Research Initiative Database Group
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: Many people with tinnitus also suffer from hyperacusis. Both clinical and basic scientific data indicate an overlap in pathophysiologic mechanisms. In order to further elucidate the interplay between tinnitus and hyperacusis we compared clinical and demographic characteristics of tinnitus patients with and without hyperacusis by analyzing a large sample from an international tinnitus patient database. Materials: The default dataset import [November 1st, 2012] from the Tinnitus Research Initiative [TRI] Database was used for analyses. Hyperacusis was defined by the question “Do sounds cause you pain or physical discomfort?” of the Tinnitus Sample Case History Questionnaire. Patients who answered this question with “yes” were contrasted with “no”-responders with respect to 41 variables. Results: 935 [55%] out of 1713 patients were characterized as hyperacusis patients. Hyperacusis in tinnitus was associated with younger age, higher tinnitus-related, mental and general distress; and higher rates of pain disorders and vertigo. In relation to objective audiological assessment patients with hyperacusis rated their subjective hearing function worse than those without hyperacusis. Similarly the tinnitus pitch was rated higher by hyperacusis patients in relation to the audiometrically determined tinnitus pitch. Among patients with tinnitus and hyperacusis the tinnitus was more frequently modulated by external noise and somatic maneuvers, i.e., exposure to environmental sounds and head and neck movements change the tinnitus percept. Conclusions: Our findings suggest that the comorbidity of hyperacusis is a useful criterion for defining a sub-type of tinnitus which is characterized by greater need of treatment. The higher sensitivity to auditory, somatosensory and vestibular input confirms the notion of an overactivation of an unspecific hypervigilance network in tinnitus patients with hyperacusis.
Fil: Schecklmann, Martin. University of Regensburg. Department of Psychiatry and Psychotherapy; Alemania
Fil: Landgraebe, Michael. Social Foundation Bamberg. Department of Psychiatry and Psychotherapy; Alemania
Fil: Langguth, Berthold. University of Regensburg. Department of Psychiatry and Psychotherapy; Alemania
Fil: Elgoyhen, Ana Belen. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular; Argentina. Tinnitus Research Initiative Database Group; Alemania
Fil: Tinnitus Research Initiative Database Group.
Materia
Tinnitus
Hypercusis
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/3973

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spelling Phenotypic Characteristics of Hyperacusis in TinnitusSchecklmann, MartinLandgraebe, MichaelLangguth, BertholdElgoyhen, Ana BelenTinnitus Research Initiative Database GroupTinnitusHypercusishttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Background: Many people with tinnitus also suffer from hyperacusis. Both clinical and basic scientific data indicate an overlap in pathophysiologic mechanisms. In order to further elucidate the interplay between tinnitus and hyperacusis we compared clinical and demographic characteristics of tinnitus patients with and without hyperacusis by analyzing a large sample from an international tinnitus patient database. Materials: The default dataset import [November 1st, 2012] from the Tinnitus Research Initiative [TRI] Database was used for analyses. Hyperacusis was defined by the question “Do sounds cause you pain or physical discomfort?” of the Tinnitus Sample Case History Questionnaire. Patients who answered this question with “yes” were contrasted with “no”-responders with respect to 41 variables. Results: 935 [55%] out of 1713 patients were characterized as hyperacusis patients. Hyperacusis in tinnitus was associated with younger age, higher tinnitus-related, mental and general distress; and higher rates of pain disorders and vertigo. In relation to objective audiological assessment patients with hyperacusis rated their subjective hearing function worse than those without hyperacusis. Similarly the tinnitus pitch was rated higher by hyperacusis patients in relation to the audiometrically determined tinnitus pitch. Among patients with tinnitus and hyperacusis the tinnitus was more frequently modulated by external noise and somatic maneuvers, i.e., exposure to environmental sounds and head and neck movements change the tinnitus percept. Conclusions: Our findings suggest that the comorbidity of hyperacusis is a useful criterion for defining a sub-type of tinnitus which is characterized by greater need of treatment. The higher sensitivity to auditory, somatosensory and vestibular input confirms the notion of an overactivation of an unspecific hypervigilance network in tinnitus patients with hyperacusis.Fil: Schecklmann, Martin. University of Regensburg. Department of Psychiatry and Psychotherapy; AlemaniaFil: Landgraebe, Michael. Social Foundation Bamberg. Department of Psychiatry and Psychotherapy; AlemaniaFil: Langguth, Berthold. University of Regensburg. Department of Psychiatry and Psychotherapy; AlemaniaFil: Elgoyhen, Ana Belen. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular; Argentina. Tinnitus Research Initiative Database Group; AlemaniaFil: Tinnitus Research Initiative Database Group.Public Library of Science2014-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/3973Schecklmann, Martin; Landgraebe, Michael; Langguth, Berthold; Elgoyhen, Ana Belen; Tinnitus Research Initiative Database Group; Phenotypic Characteristics of Hyperacusis in Tinnitus; Public Library of Science; Plos One; 9; 1; 2-2014; e86944-e869441932-6203enginfo:eu-repo/semantics/altIdentifier/url/http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0086944info:eu-repo/semantics/altIdentifier/url/http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908961/info:eu-repo/semantics/altIdentifier/issn/1932-6203info:eu-repo/semantics/altIdentifier/doi/10.1371%2Fjournal.pone.0086944info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:43:23Zoai:ri.conicet.gov.ar:11336/3973instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:43:23.712CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Phenotypic Characteristics of Hyperacusis in Tinnitus
title Phenotypic Characteristics of Hyperacusis in Tinnitus
spellingShingle Phenotypic Characteristics of Hyperacusis in Tinnitus
Schecklmann, Martin
Tinnitus
Hypercusis
title_short Phenotypic Characteristics of Hyperacusis in Tinnitus
title_full Phenotypic Characteristics of Hyperacusis in Tinnitus
title_fullStr Phenotypic Characteristics of Hyperacusis in Tinnitus
title_full_unstemmed Phenotypic Characteristics of Hyperacusis in Tinnitus
title_sort Phenotypic Characteristics of Hyperacusis in Tinnitus
dc.creator.none.fl_str_mv Schecklmann, Martin
Landgraebe, Michael
Langguth, Berthold
Elgoyhen, Ana Belen
Tinnitus Research Initiative Database Group
author Schecklmann, Martin
author_facet Schecklmann, Martin
Landgraebe, Michael
Langguth, Berthold
Elgoyhen, Ana Belen
Tinnitus Research Initiative Database Group
author_role author
author2 Landgraebe, Michael
Langguth, Berthold
Elgoyhen, Ana Belen
Tinnitus Research Initiative Database Group
author2_role author
author
author
author
dc.subject.none.fl_str_mv Tinnitus
Hypercusis
topic Tinnitus
Hypercusis
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Background: Many people with tinnitus also suffer from hyperacusis. Both clinical and basic scientific data indicate an overlap in pathophysiologic mechanisms. In order to further elucidate the interplay between tinnitus and hyperacusis we compared clinical and demographic characteristics of tinnitus patients with and without hyperacusis by analyzing a large sample from an international tinnitus patient database. Materials: The default dataset import [November 1st, 2012] from the Tinnitus Research Initiative [TRI] Database was used for analyses. Hyperacusis was defined by the question “Do sounds cause you pain or physical discomfort?” of the Tinnitus Sample Case History Questionnaire. Patients who answered this question with “yes” were contrasted with “no”-responders with respect to 41 variables. Results: 935 [55%] out of 1713 patients were characterized as hyperacusis patients. Hyperacusis in tinnitus was associated with younger age, higher tinnitus-related, mental and general distress; and higher rates of pain disorders and vertigo. In relation to objective audiological assessment patients with hyperacusis rated their subjective hearing function worse than those without hyperacusis. Similarly the tinnitus pitch was rated higher by hyperacusis patients in relation to the audiometrically determined tinnitus pitch. Among patients with tinnitus and hyperacusis the tinnitus was more frequently modulated by external noise and somatic maneuvers, i.e., exposure to environmental sounds and head and neck movements change the tinnitus percept. Conclusions: Our findings suggest that the comorbidity of hyperacusis is a useful criterion for defining a sub-type of tinnitus which is characterized by greater need of treatment. The higher sensitivity to auditory, somatosensory and vestibular input confirms the notion of an overactivation of an unspecific hypervigilance network in tinnitus patients with hyperacusis.
Fil: Schecklmann, Martin. University of Regensburg. Department of Psychiatry and Psychotherapy; Alemania
Fil: Landgraebe, Michael. Social Foundation Bamberg. Department of Psychiatry and Psychotherapy; Alemania
Fil: Langguth, Berthold. University of Regensburg. Department of Psychiatry and Psychotherapy; Alemania
Fil: Elgoyhen, Ana Belen. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular; Argentina. Tinnitus Research Initiative Database Group; Alemania
Fil: Tinnitus Research Initiative Database Group.
description Background: Many people with tinnitus also suffer from hyperacusis. Both clinical and basic scientific data indicate an overlap in pathophysiologic mechanisms. In order to further elucidate the interplay between tinnitus and hyperacusis we compared clinical and demographic characteristics of tinnitus patients with and without hyperacusis by analyzing a large sample from an international tinnitus patient database. Materials: The default dataset import [November 1st, 2012] from the Tinnitus Research Initiative [TRI] Database was used for analyses. Hyperacusis was defined by the question “Do sounds cause you pain or physical discomfort?” of the Tinnitus Sample Case History Questionnaire. Patients who answered this question with “yes” were contrasted with “no”-responders with respect to 41 variables. Results: 935 [55%] out of 1713 patients were characterized as hyperacusis patients. Hyperacusis in tinnitus was associated with younger age, higher tinnitus-related, mental and general distress; and higher rates of pain disorders and vertigo. In relation to objective audiological assessment patients with hyperacusis rated their subjective hearing function worse than those without hyperacusis. Similarly the tinnitus pitch was rated higher by hyperacusis patients in relation to the audiometrically determined tinnitus pitch. Among patients with tinnitus and hyperacusis the tinnitus was more frequently modulated by external noise and somatic maneuvers, i.e., exposure to environmental sounds and head and neck movements change the tinnitus percept. Conclusions: Our findings suggest that the comorbidity of hyperacusis is a useful criterion for defining a sub-type of tinnitus which is characterized by greater need of treatment. The higher sensitivity to auditory, somatosensory and vestibular input confirms the notion of an overactivation of an unspecific hypervigilance network in tinnitus patients with hyperacusis.
publishDate 2014
dc.date.none.fl_str_mv 2014-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/3973
Schecklmann, Martin; Landgraebe, Michael; Langguth, Berthold; Elgoyhen, Ana Belen; Tinnitus Research Initiative Database Group; Phenotypic Characteristics of Hyperacusis in Tinnitus; Public Library of Science; Plos One; 9; 1; 2-2014; e86944-e86944
1932-6203
url http://hdl.handle.net/11336/3973
identifier_str_mv Schecklmann, Martin; Landgraebe, Michael; Langguth, Berthold; Elgoyhen, Ana Belen; Tinnitus Research Initiative Database Group; Phenotypic Characteristics of Hyperacusis in Tinnitus; Public Library of Science; Plos One; 9; 1; 2-2014; e86944-e86944
1932-6203
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0086944
info:eu-repo/semantics/altIdentifier/url/http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908961/
info:eu-repo/semantics/altIdentifier/issn/1932-6203
info:eu-repo/semantics/altIdentifier/doi/10.1371%2Fjournal.pone.0086944
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https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
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application/pdf
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
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