LncRNA DANA1 promotes drought tolerance and histone deacetylation of drought responsive genes in Arabidopsis

Autores
Cai, Jingjing; Zhang, Yongdi; He, Reqing; Jiang, Liyun; Qu, Zhipeng; Gu, Jinbao; Yang, Jun; Legascue, María Florencia; Wang, Zhen Yu; Ariel, Federico Damian; Adelson, David L.; Zhu, Youlin; Wang, Dong
Año de publicación
2024
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Although many long noncoding RNAs have been discovered in plants, little is known about their biological function and mode of action. Here we show that the drought-induced long intergenic noncoding RNA DANA1 interacts with the L1p/L10e family member protein DANA1-INTERACTING PROTEIN 1 (DIP1) in the cell nucleus of Arabidopsis, and both DANA1 and DIP1 promote plant drought resistance. DANA1 and DIP1 increase histone deacetylase HDA9 binding to the CYP707A1 and CYP707A2 loci. DIP1 further interacts with PWWP3, a member of the PEAT complex that associates with HDA9 and has histone deacetylase activity. Mutation of DANA1 enhances CYP707A1 and CYP707A2 acetylation and expression resulting in impaired drought tolerance, in agreement with dip1 and pwwp3 mutant phenotypes. Our results demonstrate that DANA1 is a positive regulator of drought response and that DANA1 works jointly with the novel chromatin-related factor DIP1 on epigenetic reprogramming of the plant transcriptome during the response to drought.
Fil: Cai, Jingjing. Nanchang University; China
Fil: Zhang, Yongdi. Nanchang University; China
Fil: He, Reqing. Nanchang University; China
Fil: Jiang, Liyun. Nanchang University; China
Fil: Qu, Zhipeng. University of Adelaide; Australia
Fil: Gu, Jinbao. Guangdong Academy of Sciences; China
Fil: Yang, Jun. Nanchang University; China
Fil: Legascue, María Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina
Fil: Wang, Zhen Yu. Guangdong Academy of Sciences; China
Fil: Ariel, Federico Damian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina
Fil: Adelson, David L.. University of Adelaide; Australia
Fil: Zhu, Youlin. Nanchang University; China
Fil: Wang, Dong. Nanchang University; China
Materia
LNCRNA
STRESS
ARABIDOPSIS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/265614
Acceder
id CONICETDig_42c16bea9ba67a55d3c199fb7db9c1b2
oai_identifier_str oai:ri.conicet.gov.ar:11336/265614
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling LncRNA DANA1 promotes drought tolerance and histone deacetylation of drought responsive genes in ArabidopsisCai, JingjingZhang, YongdiHe, ReqingJiang, LiyunQu, ZhipengGu, JinbaoYang, JunLegascue, María FlorenciaWang, Zhen YuAriel, Federico DamianAdelson, David L.Zhu, YoulinWang, DongLNCRNASTRESSARABIDOPSIShttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Although many long noncoding RNAs have been discovered in plants, little is known about their biological function and mode of action. Here we show that the drought-induced long intergenic noncoding RNA DANA1 interacts with the L1p/L10e family member protein DANA1-INTERACTING PROTEIN 1 (DIP1) in the cell nucleus of Arabidopsis, and both DANA1 and DIP1 promote plant drought resistance. DANA1 and DIP1 increase histone deacetylase HDA9 binding to the CYP707A1 and CYP707A2 loci. DIP1 further interacts with PWWP3, a member of the PEAT complex that associates with HDA9 and has histone deacetylase activity. Mutation of DANA1 enhances CYP707A1 and CYP707A2 acetylation and expression resulting in impaired drought tolerance, in agreement with dip1 and pwwp3 mutant phenotypes. Our results demonstrate that DANA1 is a positive regulator of drought response and that DANA1 works jointly with the novel chromatin-related factor DIP1 on epigenetic reprogramming of the plant transcriptome during the response to drought.Fil: Cai, Jingjing. Nanchang University; ChinaFil: Zhang, Yongdi. Nanchang University; ChinaFil: He, Reqing. Nanchang University; ChinaFil: Jiang, Liyun. Nanchang University; ChinaFil: Qu, Zhipeng. University of Adelaide; AustraliaFil: Gu, Jinbao. Guangdong Academy of Sciences; ChinaFil: Yang, Jun. Nanchang University; ChinaFil: Legascue, María Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; ArgentinaFil: Wang, Zhen Yu. Guangdong Academy of Sciences; ChinaFil: Ariel, Federico Damian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; ArgentinaFil: Adelson, David L.. University of Adelaide; AustraliaFil: Zhu, Youlin. Nanchang University; ChinaFil: Wang, Dong. Nanchang University; ChinaEMBO Press2024-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/265614Cai, Jingjing; Zhang, Yongdi; He, Reqing; Jiang, Liyun; Qu, Zhipeng; et al.; LncRNA DANA1 promotes drought tolerance and histone deacetylation of drought responsive genes in Arabidopsis; EMBO Press; EMBO Reports; 25; 2; 1-2024; 796-8121469-3178CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.embopress.org/doi/full/10.1038/s44319-023-00030-4info:eu-repo/semantics/altIdentifier/doi/10.1038/s44319-023-00030-4info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-11-05T09:50:23Zoai:ri.conicet.gov.ar:11336/265614instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-11-05 09:50:23.691CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv LncRNA DANA1 promotes drought tolerance and histone deacetylation of drought responsive genes in Arabidopsis
title LncRNA DANA1 promotes drought tolerance and histone deacetylation of drought responsive genes in Arabidopsis
spellingShingle LncRNA DANA1 promotes drought tolerance and histone deacetylation of drought responsive genes in Arabidopsis
Cai, Jingjing
LNCRNA
STRESS
ARABIDOPSIS
title_short LncRNA DANA1 promotes drought tolerance and histone deacetylation of drought responsive genes in Arabidopsis
title_full LncRNA DANA1 promotes drought tolerance and histone deacetylation of drought responsive genes in Arabidopsis
title_fullStr LncRNA DANA1 promotes drought tolerance and histone deacetylation of drought responsive genes in Arabidopsis
title_full_unstemmed LncRNA DANA1 promotes drought tolerance and histone deacetylation of drought responsive genes in Arabidopsis
title_sort LncRNA DANA1 promotes drought tolerance and histone deacetylation of drought responsive genes in Arabidopsis
dc.creator.none.fl_str_mv Cai, Jingjing
Zhang, Yongdi
He, Reqing
Jiang, Liyun
Qu, Zhipeng
Gu, Jinbao
Yang, Jun
Legascue, María Florencia
Wang, Zhen Yu
Ariel, Federico Damian
Adelson, David L.
Zhu, Youlin
Wang, Dong
author Cai, Jingjing
author_facet Cai, Jingjing
Zhang, Yongdi
He, Reqing
Jiang, Liyun
Qu, Zhipeng
Gu, Jinbao
Yang, Jun
Legascue, María Florencia
Wang, Zhen Yu
Ariel, Federico Damian
Adelson, David L.
Zhu, Youlin
Wang, Dong
author_role author
author2 Zhang, Yongdi
He, Reqing
Jiang, Liyun
Qu, Zhipeng
Gu, Jinbao
Yang, Jun
Legascue, María Florencia
Wang, Zhen Yu
Ariel, Federico Damian
Adelson, David L.
Zhu, Youlin
Wang, Dong
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv LNCRNA
STRESS
ARABIDOPSIS
topic LNCRNA
STRESS
ARABIDOPSIS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Although many long noncoding RNAs have been discovered in plants, little is known about their biological function and mode of action. Here we show that the drought-induced long intergenic noncoding RNA DANA1 interacts with the L1p/L10e family member protein DANA1-INTERACTING PROTEIN 1 (DIP1) in the cell nucleus of Arabidopsis, and both DANA1 and DIP1 promote plant drought resistance. DANA1 and DIP1 increase histone deacetylase HDA9 binding to the CYP707A1 and CYP707A2 loci. DIP1 further interacts with PWWP3, a member of the PEAT complex that associates with HDA9 and has histone deacetylase activity. Mutation of DANA1 enhances CYP707A1 and CYP707A2 acetylation and expression resulting in impaired drought tolerance, in agreement with dip1 and pwwp3 mutant phenotypes. Our results demonstrate that DANA1 is a positive regulator of drought response and that DANA1 works jointly with the novel chromatin-related factor DIP1 on epigenetic reprogramming of the plant transcriptome during the response to drought.
Fil: Cai, Jingjing. Nanchang University; China
Fil: Zhang, Yongdi. Nanchang University; China
Fil: He, Reqing. Nanchang University; China
Fil: Jiang, Liyun. Nanchang University; China
Fil: Qu, Zhipeng. University of Adelaide; Australia
Fil: Gu, Jinbao. Guangdong Academy of Sciences; China
Fil: Yang, Jun. Nanchang University; China
Fil: Legascue, María Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina
Fil: Wang, Zhen Yu. Guangdong Academy of Sciences; China
Fil: Ariel, Federico Damian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina
Fil: Adelson, David L.. University of Adelaide; Australia
Fil: Zhu, Youlin. Nanchang University; China
Fil: Wang, Dong. Nanchang University; China
description Although many long noncoding RNAs have been discovered in plants, little is known about their biological function and mode of action. Here we show that the drought-induced long intergenic noncoding RNA DANA1 interacts with the L1p/L10e family member protein DANA1-INTERACTING PROTEIN 1 (DIP1) in the cell nucleus of Arabidopsis, and both DANA1 and DIP1 promote plant drought resistance. DANA1 and DIP1 increase histone deacetylase HDA9 binding to the CYP707A1 and CYP707A2 loci. DIP1 further interacts with PWWP3, a member of the PEAT complex that associates with HDA9 and has histone deacetylase activity. Mutation of DANA1 enhances CYP707A1 and CYP707A2 acetylation and expression resulting in impaired drought tolerance, in agreement with dip1 and pwwp3 mutant phenotypes. Our results demonstrate that DANA1 is a positive regulator of drought response and that DANA1 works jointly with the novel chromatin-related factor DIP1 on epigenetic reprogramming of the plant transcriptome during the response to drought.
publishDate 2024
dc.date.none.fl_str_mv 2024-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/265614
Cai, Jingjing; Zhang, Yongdi; He, Reqing; Jiang, Liyun; Qu, Zhipeng; et al.; LncRNA DANA1 promotes drought tolerance and histone deacetylation of drought responsive genes in Arabidopsis; EMBO Press; EMBO Reports; 25; 2; 1-2024; 796-812
1469-3178
CONICET Digital
CONICET
url http://hdl.handle.net/11336/265614
identifier_str_mv Cai, Jingjing; Zhang, Yongdi; He, Reqing; Jiang, Liyun; Qu, Zhipeng; et al.; LncRNA DANA1 promotes drought tolerance and histone deacetylation of drought responsive genes in Arabidopsis; EMBO Press; EMBO Reports; 25; 2; 1-2024; 796-812
1469-3178
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.embopress.org/doi/full/10.1038/s44319-023-00030-4
info:eu-repo/semantics/altIdentifier/doi/10.1038/s44319-023-00030-4
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv EMBO Press
publisher.none.fl_str_mv EMBO Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1847977212878258176
score 13.087074

Publicaciones similares