Antimicrobial Nanoformulations Based on Schinus areira Essential Oil

Autores
Cutró, Andrea Carmen; Ferreyra Maillard, Anike Paula Virginia; Dalmasso, Pablo Roberto; Rodríguez, Sergio Antonio; Hollmann, Axel
Año de publicación
2023
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The goal of this research was to create an antibacterial formulation from Scinus areiraessential oil (EO) that could spread in water. To achieve this, we developed liposomal formulationsof DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) or DPPC (1,2-dipalmitoyl-sn-glycero-3-phosphocholine) that encapsulated the EO. In addition, we utilized the EO as a reducing andstabilizing agent to synthesize silver nanoparticles (AgNPs). The nanoformulations were characterizedby determining their size and zeta potential. In the case of liposomal formulations, chemicalcomposition, and encapsulation efficiency were also determined. Furthermore, antimicrobial activitystudies against Gram-positive and Gram-negative model bacteria were carried out for both kindsof formulations. The results obtained showed the successful encapsulation of the S. areira EO inmultilamellar liposomes of phosphatidylcholine with high efficiency. DPPC liposomes have proven tobe a better encapsulation system, retaining more monoterpenes from the EO and therefore presentingantimicrobial activity against S. aureus with an minimal inhibitory concentration (MIC) value of3 mg/mL of EO. On the other hand, it was also possible to obtain AgNPs by using S. areira EO,which showed antimicrobial activity against S. aureus and E. coli at low concentrations of EO, withMIC values of 6.68 g/mL and 3.4 g/mL of silver, respectively. The data obtained will contributeto enhancing the biotechnological value of natural products derived from native plant species inArgentina. This will be achieved through the generation of novel formulations with antibacterialactivity and potential bioavailability.
Fil: Cutró, Andrea Carmen. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; Argentina. Universidad Nacional de Santiago del Estero. Facultad de Ciencias Medicas.; Argentina
Fil: Ferreyra Maillard, Anike Paula Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; Argentina
Fil: Dalmasso, Pablo Roberto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Tecnologica Nacional. Facultad Regional Cordoba. Departamento de Ingenieria Quimica. Centro de Investigacion y Transferencia En Ingenieria Quimica.; Argentina
Fil: Rodríguez, Sergio Antonio. Universidad Nacional de Santiago del Estero. Facultad de Agronomía y Agroindustrias. Instituto de Ciencias Químicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Hollmann, Axel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; Argentina. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Microbiología Molecular; Argentina
Materia
SCHINUS AREIRA
LIPOSOMES
GREEN SYNTHESIS OF NANOPARTICLES
ESSENTIAL OIL
ANTIMICROBIALS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/222502
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/222502
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Antimicrobial Nanoformulations Based on Schinus areira Essential OilCutró, Andrea CarmenFerreyra Maillard, Anike Paula VirginiaDalmasso, Pablo RobertoRodríguez, Sergio AntonioHollmann, AxelSCHINUS AREIRALIPOSOMESGREEN SYNTHESIS OF NANOPARTICLESESSENTIAL OILANTIMICROBIALShttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1https://purl.org/becyt/ford/2.10https://purl.org/becyt/ford/2The goal of this research was to create an antibacterial formulation from Scinus areiraessential oil (EO) that could spread in water. To achieve this, we developed liposomal formulationsof DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) or DPPC (1,2-dipalmitoyl-sn-glycero-3-phosphocholine) that encapsulated the EO. In addition, we utilized the EO as a reducing andstabilizing agent to synthesize silver nanoparticles (AgNPs). The nanoformulations were characterizedby determining their size and zeta potential. In the case of liposomal formulations, chemicalcomposition, and encapsulation efficiency were also determined. Furthermore, antimicrobial activitystudies against Gram-positive and Gram-negative model bacteria were carried out for both kindsof formulations. The results obtained showed the successful encapsulation of the S. areira EO inmultilamellar liposomes of phosphatidylcholine with high efficiency. DPPC liposomes have proven tobe a better encapsulation system, retaining more monoterpenes from the EO and therefore presentingantimicrobial activity against S. aureus with an minimal inhibitory concentration (MIC) value of3 mg/mL of EO. On the other hand, it was also possible to obtain AgNPs by using S. areira EO,which showed antimicrobial activity against S. aureus and E. coli at low concentrations of EO, withMIC values of 6.68 g/mL and 3.4 g/mL of silver, respectively. The data obtained will contributeto enhancing the biotechnological value of natural products derived from native plant species inArgentina. This will be achieved through the generation of novel formulations with antibacterialactivity and potential bioavailability.Fil: Cutró, Andrea Carmen. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; Argentina. Universidad Nacional de Santiago del Estero. Facultad de Ciencias Medicas.; ArgentinaFil: Ferreyra Maillard, Anike Paula Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; ArgentinaFil: Dalmasso, Pablo Roberto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Tecnologica Nacional. Facultad Regional Cordoba. Departamento de Ingenieria Quimica. Centro de Investigacion y Transferencia En Ingenieria Quimica.; ArgentinaFil: Rodríguez, Sergio Antonio. Universidad Nacional de Santiago del Estero. Facultad de Agronomía y Agroindustrias. Instituto de Ciencias Químicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Hollmann, Axel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; Argentina. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Microbiología Molecular; ArgentinaMDPI2023-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/222502Cutró, Andrea Carmen; Ferreyra Maillard, Anike Paula Virginia; Dalmasso, Pablo Roberto; Rodríguez, Sergio Antonio; Hollmann, Axel; Antimicrobial Nanoformulations Based on Schinus areira Essential Oil; MDPI; Drugs and Drugs Candidates; 2; 6-2023; 498-5152813-2998CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2813-2998/2/2/26info:eu-repo/semantics/altIdentifier/doi/10.3390/ddc2020026info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:08:16Zoai:ri.conicet.gov.ar:11336/222502instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:08:16.707CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Antimicrobial Nanoformulations Based on Schinus areira Essential Oil
title Antimicrobial Nanoformulations Based on Schinus areira Essential Oil
spellingShingle Antimicrobial Nanoformulations Based on Schinus areira Essential Oil
Cutró, Andrea Carmen
SCHINUS AREIRA
LIPOSOMES
GREEN SYNTHESIS OF NANOPARTICLES
ESSENTIAL OIL
ANTIMICROBIALS
title_short Antimicrobial Nanoformulations Based on Schinus areira Essential Oil
title_full Antimicrobial Nanoformulations Based on Schinus areira Essential Oil
title_fullStr Antimicrobial Nanoformulations Based on Schinus areira Essential Oil
title_full_unstemmed Antimicrobial Nanoformulations Based on Schinus areira Essential Oil
title_sort Antimicrobial Nanoformulations Based on Schinus areira Essential Oil
dc.creator.none.fl_str_mv Cutró, Andrea Carmen
Ferreyra Maillard, Anike Paula Virginia
Dalmasso, Pablo Roberto
Rodríguez, Sergio Antonio
Hollmann, Axel
author Cutró, Andrea Carmen
author_facet Cutró, Andrea Carmen
Ferreyra Maillard, Anike Paula Virginia
Dalmasso, Pablo Roberto
Rodríguez, Sergio Antonio
Hollmann, Axel
author_role author
author2 Ferreyra Maillard, Anike Paula Virginia
Dalmasso, Pablo Roberto
Rodríguez, Sergio Antonio
Hollmann, Axel
author2_role author
author
author
author
dc.subject.none.fl_str_mv SCHINUS AREIRA
LIPOSOMES
GREEN SYNTHESIS OF NANOPARTICLES
ESSENTIAL OIL
ANTIMICROBIALS
topic SCHINUS AREIRA
LIPOSOMES
GREEN SYNTHESIS OF NANOPARTICLES
ESSENTIAL OIL
ANTIMICROBIALS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
https://purl.org/becyt/ford/2.10
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv The goal of this research was to create an antibacterial formulation from Scinus areiraessential oil (EO) that could spread in water. To achieve this, we developed liposomal formulationsof DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) or DPPC (1,2-dipalmitoyl-sn-glycero-3-phosphocholine) that encapsulated the EO. In addition, we utilized the EO as a reducing andstabilizing agent to synthesize silver nanoparticles (AgNPs). The nanoformulations were characterizedby determining their size and zeta potential. In the case of liposomal formulations, chemicalcomposition, and encapsulation efficiency were also determined. Furthermore, antimicrobial activitystudies against Gram-positive and Gram-negative model bacteria were carried out for both kindsof formulations. The results obtained showed the successful encapsulation of the S. areira EO inmultilamellar liposomes of phosphatidylcholine with high efficiency. DPPC liposomes have proven tobe a better encapsulation system, retaining more monoterpenes from the EO and therefore presentingantimicrobial activity against S. aureus with an minimal inhibitory concentration (MIC) value of3 mg/mL of EO. On the other hand, it was also possible to obtain AgNPs by using S. areira EO,which showed antimicrobial activity against S. aureus and E. coli at low concentrations of EO, withMIC values of 6.68 g/mL and 3.4 g/mL of silver, respectively. The data obtained will contributeto enhancing the biotechnological value of natural products derived from native plant species inArgentina. This will be achieved through the generation of novel formulations with antibacterialactivity and potential bioavailability.
Fil: Cutró, Andrea Carmen. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; Argentina. Universidad Nacional de Santiago del Estero. Facultad de Ciencias Medicas.; Argentina
Fil: Ferreyra Maillard, Anike Paula Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; Argentina
Fil: Dalmasso, Pablo Roberto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Tecnologica Nacional. Facultad Regional Cordoba. Departamento de Ingenieria Quimica. Centro de Investigacion y Transferencia En Ingenieria Quimica.; Argentina
Fil: Rodríguez, Sergio Antonio. Universidad Nacional de Santiago del Estero. Facultad de Agronomía y Agroindustrias. Instituto de Ciencias Químicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Hollmann, Axel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Centro de Investigación en Biofísica Aplicada y Alimentos. - Universidad Nacional de Santiago del Estero. Centro de Investigación en Biofísica Aplicada y Alimentos; Argentina. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Microbiología Molecular; Argentina
description The goal of this research was to create an antibacterial formulation from Scinus areiraessential oil (EO) that could spread in water. To achieve this, we developed liposomal formulationsof DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) or DPPC (1,2-dipalmitoyl-sn-glycero-3-phosphocholine) that encapsulated the EO. In addition, we utilized the EO as a reducing andstabilizing agent to synthesize silver nanoparticles (AgNPs). The nanoformulations were characterizedby determining their size and zeta potential. In the case of liposomal formulations, chemicalcomposition, and encapsulation efficiency were also determined. Furthermore, antimicrobial activitystudies against Gram-positive and Gram-negative model bacteria were carried out for both kindsof formulations. The results obtained showed the successful encapsulation of the S. areira EO inmultilamellar liposomes of phosphatidylcholine with high efficiency. DPPC liposomes have proven tobe a better encapsulation system, retaining more monoterpenes from the EO and therefore presentingantimicrobial activity against S. aureus with an minimal inhibitory concentration (MIC) value of3 mg/mL of EO. On the other hand, it was also possible to obtain AgNPs by using S. areira EO,which showed antimicrobial activity against S. aureus and E. coli at low concentrations of EO, withMIC values of 6.68 g/mL and 3.4 g/mL of silver, respectively. The data obtained will contributeto enhancing the biotechnological value of natural products derived from native plant species inArgentina. This will be achieved through the generation of novel formulations with antibacterialactivity and potential bioavailability.
publishDate 2023
dc.date.none.fl_str_mv 2023-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/222502
Cutró, Andrea Carmen; Ferreyra Maillard, Anike Paula Virginia; Dalmasso, Pablo Roberto; Rodríguez, Sergio Antonio; Hollmann, Axel; Antimicrobial Nanoformulations Based on Schinus areira Essential Oil; MDPI; Drugs and Drugs Candidates; 2; 6-2023; 498-515
2813-2998
CONICET Digital
CONICET
url http://hdl.handle.net/11336/222502
identifier_str_mv Cutró, Andrea Carmen; Ferreyra Maillard, Anike Paula Virginia; Dalmasso, Pablo Roberto; Rodríguez, Sergio Antonio; Hollmann, Axel; Antimicrobial Nanoformulations Based on Schinus areira Essential Oil; MDPI; Drugs and Drugs Candidates; 2; 6-2023; 498-515
2813-2998
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2813-2998/2/2/26
info:eu-repo/semantics/altIdentifier/doi/10.3390/ddc2020026
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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