Estudio de Síntomas Neuropsiquiátricos y Neuropsicológicos en pacientes con Enfermedad de Parkinson seleccionados para la cirugía de estimulación cerebral profunda

Autores
Dillon, Carol; Leis, Adriana Mónica; Castro, Diego M.; García, Virginia; Zegarra, Cecilia; Perez Leguizamón, Patricio; Feldman, Mónica; Driollet Laspiur, Santiago; Viaggio, Maria Belen; Peralta, Cecilia
Año de publicación
2022
Idioma
español castellano
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Introduction: Parkinson's disease (PD) is a neurodegenerative disease that combines motor and non-motor symptoms. The motor symptoms are cardinal, however, these patients also present associated psychiatric and neuropsychological symptoms. Deep brain stimulation surgery (DBS) is a treatment used for patients in fluctuating and advanced phases of PD. The objective of this work is to detect psychiatric and neuropsychological signs and symptoms in patients with PD who are candidates for DBS surgery. Patients and methods: An observational cross-sectional cohort study was performed. Forty-one patients with a diagnosis of PD were evaluated. Patients were assessed with a semi-structured neuropsychiatric interview, neuropsychiatric scales, and a complete neuropsychological battery. Statistical analysis: A complete descriptive statistical analysis was carried out, correlations were evaluated with the Pearson test. Results: Forty-one patients with PD were evaluated, age 65.39 (SD 8.34), educational level of 11.95 years (SD 4.37). Previous psychiatric disorders were highly prevalent (68.5%). Mild-degree depressive symptoms and mild–moderate anxiety symptoms were observed, and impulsive symptoms and nocturnal behaviors were frequently reported. Patients presented amnesic-type cognitive impairment, with poor scores on executive and visuoconstructive tests. Significant correlations (p < 0.05) were found between the neuropsychiatric and neuropsychological scales. Conclusions: PD patients present frequently psychiatric disorders and cognitive impairment. It is of relevance to carry out a neuropsychological and neuropsychiatric evaluation with adapted and validated scales for the selection of patients for this type of surgery.
Fil: Dillon, Carol. Universidad de Palermo. Facultad de Ciencias Sociales. Departamento de Psicología; Argentina. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Leis, Adriana Mónica. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina
Fil: Castro, Diego M.. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina
Fil: García, Virginia. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina
Fil: Zegarra, Cecilia. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina
Fil: Perez Leguizamón, Patricio. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina
Fil: Feldman, Mónica. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina
Fil: Driollet Laspiur, Santiago. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina
Fil: Viaggio, Maria Belen. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina
Fil: Peralta, Cecilia. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina
Materia
DEEP BRAIN STIMULATION SURGERY
NEUROPSYCHIATRIC SYMPTOMS
NEUROPSYCHOLOGICAL SYMPTOMS
PARKINSON'S DISEASE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/200756
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/200756
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Estudio de Síntomas Neuropsiquiátricos y Neuropsicológicos en pacientes con Enfermedad de Parkinson seleccionados para la cirugía de estimulación cerebral profundaStudy of neuropsychiatric and neuropsychological symptoms in Parkinson's disease patients selected for deep brain stimulation surgeryDillon, CarolLeis, Adriana MónicaCastro, Diego M.García, VirginiaZegarra, CeciliaPerez Leguizamón, PatricioFeldman, MónicaDriollet Laspiur, SantiagoViaggio, Maria BelenPeralta, CeciliaDEEP BRAIN STIMULATION SURGERYNEUROPSYCHIATRIC SYMPTOMSNEUROPSYCHOLOGICAL SYMPTOMSPARKINSON'S DISEASEhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Introduction: Parkinson's disease (PD) is a neurodegenerative disease that combines motor and non-motor symptoms. The motor symptoms are cardinal, however, these patients also present associated psychiatric and neuropsychological symptoms. Deep brain stimulation surgery (DBS) is a treatment used for patients in fluctuating and advanced phases of PD. The objective of this work is to detect psychiatric and neuropsychological signs and symptoms in patients with PD who are candidates for DBS surgery. Patients and methods: An observational cross-sectional cohort study was performed. Forty-one patients with a diagnosis of PD were evaluated. Patients were assessed with a semi-structured neuropsychiatric interview, neuropsychiatric scales, and a complete neuropsychological battery. Statistical analysis: A complete descriptive statistical analysis was carried out, correlations were evaluated with the Pearson test. Results: Forty-one patients with PD were evaluated, age 65.39 (SD 8.34), educational level of 11.95 years (SD 4.37). Previous psychiatric disorders were highly prevalent (68.5%). Mild-degree depressive symptoms and mild–moderate anxiety symptoms were observed, and impulsive symptoms and nocturnal behaviors were frequently reported. Patients presented amnesic-type cognitive impairment, with poor scores on executive and visuoconstructive tests. Significant correlations (p < 0.05) were found between the neuropsychiatric and neuropsychological scales. Conclusions: PD patients present frequently psychiatric disorders and cognitive impairment. It is of relevance to carry out a neuropsychological and neuropsychiatric evaluation with adapted and validated scales for the selection of patients for this type of surgery.Fil: Dillon, Carol. Universidad de Palermo. Facultad de Ciencias Sociales. Departamento de Psicología; Argentina. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Leis, Adriana Mónica. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; ArgentinaFil: Castro, Diego M.. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; ArgentinaFil: García, Virginia. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; ArgentinaFil: Zegarra, Cecilia. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; ArgentinaFil: Perez Leguizamón, Patricio. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; ArgentinaFil: Feldman, Mónica. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; ArgentinaFil: Driollet Laspiur, Santiago. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; ArgentinaFil: Viaggio, Maria Belen. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; ArgentinaFil: Peralta, Cecilia. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; ArgentinaElsevier2022-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/200756Dillon, Carol; Leis, Adriana Mónica; Castro, Diego M.; García, Virginia; Zegarra, Cecilia; et al.; Estudio de Síntomas Neuropsiquiátricos y Neuropsicológicos en pacientes con Enfermedad de Parkinson seleccionados para la cirugía de estimulación cerebral profunda; Elsevier; Neurologia Argentina; 14; 4; 10-2022; 229-2381853-0028CONICET DigitalCONICETspainfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.neuarg.2022.06.001info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:00:27Zoai:ri.conicet.gov.ar:11336/200756instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:00:27.659CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Estudio de Síntomas Neuropsiquiátricos y Neuropsicológicos en pacientes con Enfermedad de Parkinson seleccionados para la cirugía de estimulación cerebral profunda
Study of neuropsychiatric and neuropsychological symptoms in Parkinson's disease patients selected for deep brain stimulation surgery
title Estudio de Síntomas Neuropsiquiátricos y Neuropsicológicos en pacientes con Enfermedad de Parkinson seleccionados para la cirugía de estimulación cerebral profunda
spellingShingle Estudio de Síntomas Neuropsiquiátricos y Neuropsicológicos en pacientes con Enfermedad de Parkinson seleccionados para la cirugía de estimulación cerebral profunda
Dillon, Carol
DEEP BRAIN STIMULATION SURGERY
NEUROPSYCHIATRIC SYMPTOMS
NEUROPSYCHOLOGICAL SYMPTOMS
PARKINSON'S DISEASE
title_short Estudio de Síntomas Neuropsiquiátricos y Neuropsicológicos en pacientes con Enfermedad de Parkinson seleccionados para la cirugía de estimulación cerebral profunda
title_full Estudio de Síntomas Neuropsiquiátricos y Neuropsicológicos en pacientes con Enfermedad de Parkinson seleccionados para la cirugía de estimulación cerebral profunda
title_fullStr Estudio de Síntomas Neuropsiquiátricos y Neuropsicológicos en pacientes con Enfermedad de Parkinson seleccionados para la cirugía de estimulación cerebral profunda
title_full_unstemmed Estudio de Síntomas Neuropsiquiátricos y Neuropsicológicos en pacientes con Enfermedad de Parkinson seleccionados para la cirugía de estimulación cerebral profunda
title_sort Estudio de Síntomas Neuropsiquiátricos y Neuropsicológicos en pacientes con Enfermedad de Parkinson seleccionados para la cirugía de estimulación cerebral profunda
dc.creator.none.fl_str_mv Dillon, Carol
Leis, Adriana Mónica
Castro, Diego M.
García, Virginia
Zegarra, Cecilia
Perez Leguizamón, Patricio
Feldman, Mónica
Driollet Laspiur, Santiago
Viaggio, Maria Belen
Peralta, Cecilia
author Dillon, Carol
author_facet Dillon, Carol
Leis, Adriana Mónica
Castro, Diego M.
García, Virginia
Zegarra, Cecilia
Perez Leguizamón, Patricio
Feldman, Mónica
Driollet Laspiur, Santiago
Viaggio, Maria Belen
Peralta, Cecilia
author_role author
author2 Leis, Adriana Mónica
Castro, Diego M.
García, Virginia
Zegarra, Cecilia
Perez Leguizamón, Patricio
Feldman, Mónica
Driollet Laspiur, Santiago
Viaggio, Maria Belen
Peralta, Cecilia
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv DEEP BRAIN STIMULATION SURGERY
NEUROPSYCHIATRIC SYMPTOMS
NEUROPSYCHOLOGICAL SYMPTOMS
PARKINSON'S DISEASE
topic DEEP BRAIN STIMULATION SURGERY
NEUROPSYCHIATRIC SYMPTOMS
NEUROPSYCHOLOGICAL SYMPTOMS
PARKINSON'S DISEASE
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Introduction: Parkinson's disease (PD) is a neurodegenerative disease that combines motor and non-motor symptoms. The motor symptoms are cardinal, however, these patients also present associated psychiatric and neuropsychological symptoms. Deep brain stimulation surgery (DBS) is a treatment used for patients in fluctuating and advanced phases of PD. The objective of this work is to detect psychiatric and neuropsychological signs and symptoms in patients with PD who are candidates for DBS surgery. Patients and methods: An observational cross-sectional cohort study was performed. Forty-one patients with a diagnosis of PD were evaluated. Patients were assessed with a semi-structured neuropsychiatric interview, neuropsychiatric scales, and a complete neuropsychological battery. Statistical analysis: A complete descriptive statistical analysis was carried out, correlations were evaluated with the Pearson test. Results: Forty-one patients with PD were evaluated, age 65.39 (SD 8.34), educational level of 11.95 years (SD 4.37). Previous psychiatric disorders were highly prevalent (68.5%). Mild-degree depressive symptoms and mild–moderate anxiety symptoms were observed, and impulsive symptoms and nocturnal behaviors were frequently reported. Patients presented amnesic-type cognitive impairment, with poor scores on executive and visuoconstructive tests. Significant correlations (p < 0.05) were found between the neuropsychiatric and neuropsychological scales. Conclusions: PD patients present frequently psychiatric disorders and cognitive impairment. It is of relevance to carry out a neuropsychological and neuropsychiatric evaluation with adapted and validated scales for the selection of patients for this type of surgery.
Fil: Dillon, Carol. Universidad de Palermo. Facultad de Ciencias Sociales. Departamento de Psicología; Argentina. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Leis, Adriana Mónica. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina
Fil: Castro, Diego M.. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina
Fil: García, Virginia. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina
Fil: Zegarra, Cecilia. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina
Fil: Perez Leguizamón, Patricio. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina
Fil: Feldman, Mónica. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina
Fil: Driollet Laspiur, Santiago. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina
Fil: Viaggio, Maria Belen. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina
Fil: Peralta, Cecilia. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; Argentina
description Introduction: Parkinson's disease (PD) is a neurodegenerative disease that combines motor and non-motor symptoms. The motor symptoms are cardinal, however, these patients also present associated psychiatric and neuropsychological symptoms. Deep brain stimulation surgery (DBS) is a treatment used for patients in fluctuating and advanced phases of PD. The objective of this work is to detect psychiatric and neuropsychological signs and symptoms in patients with PD who are candidates for DBS surgery. Patients and methods: An observational cross-sectional cohort study was performed. Forty-one patients with a diagnosis of PD were evaluated. Patients were assessed with a semi-structured neuropsychiatric interview, neuropsychiatric scales, and a complete neuropsychological battery. Statistical analysis: A complete descriptive statistical analysis was carried out, correlations were evaluated with the Pearson test. Results: Forty-one patients with PD were evaluated, age 65.39 (SD 8.34), educational level of 11.95 years (SD 4.37). Previous psychiatric disorders were highly prevalent (68.5%). Mild-degree depressive symptoms and mild–moderate anxiety symptoms were observed, and impulsive symptoms and nocturnal behaviors were frequently reported. Patients presented amnesic-type cognitive impairment, with poor scores on executive and visuoconstructive tests. Significant correlations (p < 0.05) were found between the neuropsychiatric and neuropsychological scales. Conclusions: PD patients present frequently psychiatric disorders and cognitive impairment. It is of relevance to carry out a neuropsychological and neuropsychiatric evaluation with adapted and validated scales for the selection of patients for this type of surgery.
publishDate 2022
dc.date.none.fl_str_mv 2022-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/200756
Dillon, Carol; Leis, Adriana Mónica; Castro, Diego M.; García, Virginia; Zegarra, Cecilia; et al.; Estudio de Síntomas Neuropsiquiátricos y Neuropsicológicos en pacientes con Enfermedad de Parkinson seleccionados para la cirugía de estimulación cerebral profunda; Elsevier; Neurologia Argentina; 14; 4; 10-2022; 229-238
1853-0028
CONICET Digital
CONICET
url http://hdl.handle.net/11336/200756
identifier_str_mv Dillon, Carol; Leis, Adriana Mónica; Castro, Diego M.; García, Virginia; Zegarra, Cecilia; et al.; Estudio de Síntomas Neuropsiquiátricos y Neuropsicológicos en pacientes con Enfermedad de Parkinson seleccionados para la cirugía de estimulación cerebral profunda; Elsevier; Neurologia Argentina; 14; 4; 10-2022; 229-238
1853-0028
CONICET Digital
CONICET
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.neuarg.2022.06.001
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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