Anti-quorum sensing activity of natural compounds against Chromobacterium violaceum. 2016; 1(1): 43-48.

Autores
Tomadoni, Bárbara María; Moreira, Maria del Rosario; Ponce, Alejandra Graciela
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The resistance and potential pathogenesis of bacteria could be related to their ability to sense and respond topopulation density, termed quorum-sensing (QS). Inhibition of the QS system is considered as a novel strategyfor development of antipathogenic agents, especially for combating bacterial infections caused by antibioticresistantstrains. In this work, the anti-QS activity of vanillin, geraniol and pomegranate extract was tested againstChromobacterium violaceum. Moreover, the minimum QS inhibitory concentration (MQSIC) was estimated foreach agent. MQSIC?s found were very low (0.60 mg/mL for vanillin; 0.19 µL/mL for geraniol; and 25 µg/mL forpomegranate extract). Therefore, the natural agents tested in this work are good candidates for the developmentof anti-QS compounds with potential application for the control of bacterial diseases regulated by QS systems.
Fil: Tomadoni, Bárbara María. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Moreira, Maria del Rosario. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Departamento de Ingeniería Química; Argentina
Fil: Ponce, Alejandra Graciela. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Cell-To-Cell Communication
Vanillin
Pomegranate Extract
MQSIC
Geraniol
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/156636
Acceder
id CONICETDig_3df49bc47e304d32a375bb3ab7d44865
oai_identifier_str oai:ri.conicet.gov.ar:11336/156636
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Anti-quorum sensing activity of natural compounds against Chromobacterium violaceum. 2016; 1(1): 43-48.Tomadoni, Bárbara MaríaMoreira, Maria del RosarioPonce, Alejandra GracielaCell-To-Cell CommunicationVanillinPomegranate ExtractMQSICGeraniolhttps://purl.org/becyt/ford/1.7https://purl.org/becyt/ford/1The resistance and potential pathogenesis of bacteria could be related to their ability to sense and respond topopulation density, termed quorum-sensing (QS). Inhibition of the QS system is considered as a novel strategyfor development of antipathogenic agents, especially for combating bacterial infections caused by antibioticresistantstrains. In this work, the anti-QS activity of vanillin, geraniol and pomegranate extract was tested againstChromobacterium violaceum. Moreover, the minimum QS inhibitory concentration (MQSIC) was estimated foreach agent. MQSIC?s found were very low (0.60 mg/mL for vanillin; 0.19 µL/mL for geraniol; and 25 µg/mL forpomegranate extract). Therefore, the natural agents tested in this work are good candidates for the developmentof anti-QS compounds with potential application for the control of bacterial diseases regulated by QS systems.Fil: Tomadoni, Bárbara María. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Moreira, Maria del Rosario. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Departamento de Ingeniería Química; ArgentinaFil: Ponce, Alejandra Graciela. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaOlogy Group2016-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/156636Tomadoni, Bárbara María; Moreira, Maria del Rosario; Ponce, Alejandra Graciela; Anti-quorum sensing activity of natural compounds against Chromobacterium violaceum. 2016; 1(1): 43-48.; Ology Group; Annales Food Scince and Nutraceuticals; 1; 1; 12-2016; 43-482572-1194CONICET DigitalCONICETenginfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:41:30Zoai:ri.conicet.gov.ar:11336/156636instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:41:31.18CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Anti-quorum sensing activity of natural compounds against Chromobacterium violaceum. 2016; 1(1): 43-48.
title Anti-quorum sensing activity of natural compounds against Chromobacterium violaceum. 2016; 1(1): 43-48.
spellingShingle Anti-quorum sensing activity of natural compounds against Chromobacterium violaceum. 2016; 1(1): 43-48.
Tomadoni, Bárbara María
Cell-To-Cell Communication
Vanillin
Pomegranate Extract
MQSIC
Geraniol
title_short Anti-quorum sensing activity of natural compounds against Chromobacterium violaceum. 2016; 1(1): 43-48.
title_full Anti-quorum sensing activity of natural compounds against Chromobacterium violaceum. 2016; 1(1): 43-48.
title_fullStr Anti-quorum sensing activity of natural compounds against Chromobacterium violaceum. 2016; 1(1): 43-48.
title_full_unstemmed Anti-quorum sensing activity of natural compounds against Chromobacterium violaceum. 2016; 1(1): 43-48.
title_sort Anti-quorum sensing activity of natural compounds against Chromobacterium violaceum. 2016; 1(1): 43-48.
dc.creator.none.fl_str_mv Tomadoni, Bárbara María
Moreira, Maria del Rosario
Ponce, Alejandra Graciela
author Tomadoni, Bárbara María
author_facet Tomadoni, Bárbara María
Moreira, Maria del Rosario
Ponce, Alejandra Graciela
author_role author
author2 Moreira, Maria del Rosario
Ponce, Alejandra Graciela
author2_role author
author
dc.subject.none.fl_str_mv Cell-To-Cell Communication
Vanillin
Pomegranate Extract
MQSIC
Geraniol
topic Cell-To-Cell Communication
Vanillin
Pomegranate Extract
MQSIC
Geraniol
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.7
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The resistance and potential pathogenesis of bacteria could be related to their ability to sense and respond topopulation density, termed quorum-sensing (QS). Inhibition of the QS system is considered as a novel strategyfor development of antipathogenic agents, especially for combating bacterial infections caused by antibioticresistantstrains. In this work, the anti-QS activity of vanillin, geraniol and pomegranate extract was tested againstChromobacterium violaceum. Moreover, the minimum QS inhibitory concentration (MQSIC) was estimated foreach agent. MQSIC?s found were very low (0.60 mg/mL for vanillin; 0.19 µL/mL for geraniol; and 25 µg/mL forpomegranate extract). Therefore, the natural agents tested in this work are good candidates for the developmentof anti-QS compounds with potential application for the control of bacterial diseases regulated by QS systems.
Fil: Tomadoni, Bárbara María. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Moreira, Maria del Rosario. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Departamento de Ingeniería Química; Argentina
Fil: Ponce, Alejandra Graciela. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description The resistance and potential pathogenesis of bacteria could be related to their ability to sense and respond topopulation density, termed quorum-sensing (QS). Inhibition of the QS system is considered as a novel strategyfor development of antipathogenic agents, especially for combating bacterial infections caused by antibioticresistantstrains. In this work, the anti-QS activity of vanillin, geraniol and pomegranate extract was tested againstChromobacterium violaceum. Moreover, the minimum QS inhibitory concentration (MQSIC) was estimated foreach agent. MQSIC?s found were very low (0.60 mg/mL for vanillin; 0.19 µL/mL for geraniol; and 25 µg/mL forpomegranate extract). Therefore, the natural agents tested in this work are good candidates for the developmentof anti-QS compounds with potential application for the control of bacterial diseases regulated by QS systems.
publishDate 2016
dc.date.none.fl_str_mv 2016-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/156636
Tomadoni, Bárbara María; Moreira, Maria del Rosario; Ponce, Alejandra Graciela; Anti-quorum sensing activity of natural compounds against Chromobacterium violaceum. 2016; 1(1): 43-48.; Ology Group; Annales Food Scince and Nutraceuticals; 1; 1; 12-2016; 43-48
2572-1194
CONICET Digital
CONICET
url http://hdl.handle.net/11336/156636
identifier_str_mv Tomadoni, Bárbara María; Moreira, Maria del Rosario; Ponce, Alejandra Graciela; Anti-quorum sensing activity of natural compounds against Chromobacterium violaceum. 2016; 1(1): 43-48.; Ology Group; Annales Food Scince and Nutraceuticals; 1; 1; 12-2016; 43-48
2572-1194
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Ology Group
publisher.none.fl_str_mv Ology Group
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844613311069421568
score 13.070432

Publicaciones similares