Nonlinear electronic circuit with neuron like bursting and spiking dynamics

• Autores: Savino, Guillermo Vicente; Formigli Rodriguez, Carlos Manuel
• Año de publicación: 2009
• Idioma: inglés
• Tipo de recurso: artículo
• Materia: Burster; Frequency; Bifurcation; Neuron
• Institución: Consejo Nacional de Investigaciones Científicas y Técnicas

It is difficult to design electronic nonlinear devices capable of reproducing complex oscillations because of the lack of general constructive rules, and because of stability problems related to the dynamical robustness of the circuits. This is particularly true for current analog electronic circuits that implement mathematical models of bursting and spiking neurons. Here we describe a novel, four-dimensional and dynamically robust nonlinear analog electronic circuit that is intrinsic excitable, and that displays frequency adaptation bursting and spiking oscillations. Despite differences from the classical Hodgkin–Huxley (HH) neuron model, its bifurcation sequences and dynamical properties are preserved, validating the circuit as a neuron model. The circuit's performance is based on a nonlinear interaction of fast–slow circuit blocks that can be clearly dissected, elucidating burst's starting, sustaining and stopping mechanisms, which may also operate in real neurons. Our analog circuit unit is easily linked and may be useful in building networks that perform in real-time.
Fil: Savino, Guillermo Vicente. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán; Argentina
Fil: Formigli Rodriguez, Carlos Manuel. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología; Argentina