Assessment of polypharmacy in elderly patients by using data from dispensed medications in community pharmacies: analysis of results by using different methods of estimation

Autores
Chiapella, Luciana Carla; Montemarani Menna, Jorgelina; Mamprin, María Eugenia
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background Estimating the prevalence of polypharmacy is essential for the evaluation of public health. Many different methodologies are used to determine the number of drugs used by a patient. Objective To analyse and compare three different methods (simultaneous, cumulative and continuous medication) to determine the number of drugs used by a patient, to estimate the prevalence of polypharmacy and to evaluate the possible association between polypharmacy and the gender and age of patients. Method Cross-sectional observational study carried out between April and September 2015. Data were acquired from prescriptions corresponding to 3972 patients aged 65 years old or older in ten community pharmacies in Argentina. Results The prevalence of polypharmacy varied significantly according to the method used. Major polypharmacy (use of five or more drugs) was detected in 20.5–47.1% of the patients. The association between gender, age and polypharmacy was statistically significant only when using the continuous medication method. The prevalence of minor polypharmacy (use of two to four drugs) was similar with the three methods. Conclusion These results contribute to deciding which is the best method to determine polypharmacy according to the objective of future studies and considering the advantages and disadvantages of each of them.
Fil: Chiapella, Luciana Carla. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmaceuticas. Departamento de Ciencias Fisiológicas. Area Farmacología; Argentina
Fil: Montemarani Menna, Jorgelina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmaceuticas. Departamento de Ciencias Fisiológicas. Area Farmacología; Argentina
Fil: Mamprin, María Eugenia. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmaceuticas. Departamento de Ciencias Fisiológicas. Area Farmacología; Argentina
Materia
COMMUNITY PHARMACY
DRUG UTILIZATION
ELDERLY
METHODOLOGY
POLYPHARMACY
POTENTIALLY INAPPROPRIATE MEDICATION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/96313
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Assessment of polypharmacy in elderly patients by using data from dispensed medications in community pharmacies: analysis of results by using different methods of estimationChiapella, Luciana CarlaMontemarani Menna, JorgelinaMamprin, María EugeniaCOMMUNITY PHARMACYDRUG UTILIZATIONELDERLYMETHODOLOGYPOLYPHARMACYPOTENTIALLY INAPPROPRIATE MEDICATIONhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Background Estimating the prevalence of polypharmacy is essential for the evaluation of public health. Many different methodologies are used to determine the number of drugs used by a patient. Objective To analyse and compare three different methods (simultaneous, cumulative and continuous medication) to determine the number of drugs used by a patient, to estimate the prevalence of polypharmacy and to evaluate the possible association between polypharmacy and the gender and age of patients. Method Cross-sectional observational study carried out between April and September 2015. Data were acquired from prescriptions corresponding to 3972 patients aged 65 years old or older in ten community pharmacies in Argentina. Results The prevalence of polypharmacy varied significantly according to the method used. Major polypharmacy (use of five or more drugs) was detected in 20.5–47.1% of the patients. The association between gender, age and polypharmacy was statistically significant only when using the continuous medication method. The prevalence of minor polypharmacy (use of two to four drugs) was similar with the three methods. Conclusion These results contribute to deciding which is the best method to determine polypharmacy according to the objective of future studies and considering the advantages and disadvantages of each of them.Fil: Chiapella, Luciana Carla. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmaceuticas. Departamento de Ciencias Fisiológicas. Area Farmacología; ArgentinaFil: Montemarani Menna, Jorgelina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmaceuticas. Departamento de Ciencias Fisiológicas. Area Farmacología; ArgentinaFil: Mamprin, María Eugenia. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmaceuticas. Departamento de Ciencias Fisiológicas. Area Farmacología; ArgentinaSpringer2018-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/zipapplication/pdfhttp://hdl.handle.net/11336/96313Chiapella, Luciana Carla; Montemarani Menna, Jorgelina; Mamprin, María Eugenia; Assessment of polypharmacy in elderly patients by using data from dispensed medications in community pharmacies: analysis of results by using different methods of estimation; Springer; International Journal of Clinical Pharmacy; 40; 5; 10-2018; 987-9902210-77112210-7703CONICET DigitalCONICETenghttps://ri.conicet.gov.ar/handle/11336/238482info:eu-repo/semantics/altIdentifier/doi/10.1007/s11096-018-0663-3info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs11096-018-0663-3info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:11:22Zoai:ri.conicet.gov.ar:11336/96313instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:11:22.848CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Assessment of polypharmacy in elderly patients by using data from dispensed medications in community pharmacies: analysis of results by using different methods of estimation
title Assessment of polypharmacy in elderly patients by using data from dispensed medications in community pharmacies: analysis of results by using different methods of estimation
spellingShingle Assessment of polypharmacy in elderly patients by using data from dispensed medications in community pharmacies: analysis of results by using different methods of estimation
Chiapella, Luciana Carla
COMMUNITY PHARMACY
DRUG UTILIZATION
ELDERLY
METHODOLOGY
POLYPHARMACY
POTENTIALLY INAPPROPRIATE MEDICATION
title_short Assessment of polypharmacy in elderly patients by using data from dispensed medications in community pharmacies: analysis of results by using different methods of estimation
title_full Assessment of polypharmacy in elderly patients by using data from dispensed medications in community pharmacies: analysis of results by using different methods of estimation
title_fullStr Assessment of polypharmacy in elderly patients by using data from dispensed medications in community pharmacies: analysis of results by using different methods of estimation
title_full_unstemmed Assessment of polypharmacy in elderly patients by using data from dispensed medications in community pharmacies: analysis of results by using different methods of estimation
title_sort Assessment of polypharmacy in elderly patients by using data from dispensed medications in community pharmacies: analysis of results by using different methods of estimation
dc.creator.none.fl_str_mv Chiapella, Luciana Carla
Montemarani Menna, Jorgelina
Mamprin, María Eugenia
author Chiapella, Luciana Carla
author_facet Chiapella, Luciana Carla
Montemarani Menna, Jorgelina
Mamprin, María Eugenia
author_role author
author2 Montemarani Menna, Jorgelina
Mamprin, María Eugenia
author2_role author
author
dc.subject.none.fl_str_mv COMMUNITY PHARMACY
DRUG UTILIZATION
ELDERLY
METHODOLOGY
POLYPHARMACY
POTENTIALLY INAPPROPRIATE MEDICATION
topic COMMUNITY PHARMACY
DRUG UTILIZATION
ELDERLY
METHODOLOGY
POLYPHARMACY
POTENTIALLY INAPPROPRIATE MEDICATION
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Background Estimating the prevalence of polypharmacy is essential for the evaluation of public health. Many different methodologies are used to determine the number of drugs used by a patient. Objective To analyse and compare three different methods (simultaneous, cumulative and continuous medication) to determine the number of drugs used by a patient, to estimate the prevalence of polypharmacy and to evaluate the possible association between polypharmacy and the gender and age of patients. Method Cross-sectional observational study carried out between April and September 2015. Data were acquired from prescriptions corresponding to 3972 patients aged 65 years old or older in ten community pharmacies in Argentina. Results The prevalence of polypharmacy varied significantly according to the method used. Major polypharmacy (use of five or more drugs) was detected in 20.5–47.1% of the patients. The association between gender, age and polypharmacy was statistically significant only when using the continuous medication method. The prevalence of minor polypharmacy (use of two to four drugs) was similar with the three methods. Conclusion These results contribute to deciding which is the best method to determine polypharmacy according to the objective of future studies and considering the advantages and disadvantages of each of them.
Fil: Chiapella, Luciana Carla. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmaceuticas. Departamento de Ciencias Fisiológicas. Area Farmacología; Argentina
Fil: Montemarani Menna, Jorgelina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmaceuticas. Departamento de Ciencias Fisiológicas. Area Farmacología; Argentina
Fil: Mamprin, María Eugenia. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmaceuticas. Departamento de Ciencias Fisiológicas. Area Farmacología; Argentina
description Background Estimating the prevalence of polypharmacy is essential for the evaluation of public health. Many different methodologies are used to determine the number of drugs used by a patient. Objective To analyse and compare three different methods (simultaneous, cumulative and continuous medication) to determine the number of drugs used by a patient, to estimate the prevalence of polypharmacy and to evaluate the possible association between polypharmacy and the gender and age of patients. Method Cross-sectional observational study carried out between April and September 2015. Data were acquired from prescriptions corresponding to 3972 patients aged 65 years old or older in ten community pharmacies in Argentina. Results The prevalence of polypharmacy varied significantly according to the method used. Major polypharmacy (use of five or more drugs) was detected in 20.5–47.1% of the patients. The association between gender, age and polypharmacy was statistically significant only when using the continuous medication method. The prevalence of minor polypharmacy (use of two to four drugs) was similar with the three methods. Conclusion These results contribute to deciding which is the best method to determine polypharmacy according to the objective of future studies and considering the advantages and disadvantages of each of them.
publishDate 2018
dc.date.none.fl_str_mv 2018-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/96313
Chiapella, Luciana Carla; Montemarani Menna, Jorgelina; Mamprin, María Eugenia; Assessment of polypharmacy in elderly patients by using data from dispensed medications in community pharmacies: analysis of results by using different methods of estimation; Springer; International Journal of Clinical Pharmacy; 40; 5; 10-2018; 987-990
2210-7711
2210-7703
CONICET Digital
CONICET
url http://hdl.handle.net/11336/96313
identifier_str_mv Chiapella, Luciana Carla; Montemarani Menna, Jorgelina; Mamprin, María Eugenia; Assessment of polypharmacy in elderly patients by using data from dispensed medications in community pharmacies: analysis of results by using different methods of estimation; Springer; International Journal of Clinical Pharmacy; 40; 5; 10-2018; 987-990
2210-7711
2210-7703
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://ri.conicet.gov.ar/handle/11336/238482
info:eu-repo/semantics/altIdentifier/doi/10.1007/s11096-018-0663-3
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs11096-018-0663-3
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/zip
application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.993085

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