Personality Changes in Dementia: Are They Disease Specific and Universal?

Autores
Torrente, Fernando; Pose, Mariángeles; Gleichgerrcht, Ezequiel; Torralva, Teresa; López, Pablo; Cetkovich Bakmas, Marcelo; Manes, Facundo Francisco
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Previous studies about personality changes in dementia suggest that they may be due to the disruption of the biological basis of personality traits, and hence, that they are disease specific and universal. However, evidence about its specificity is still limited and scarce regarding culturally diverse populations. Accordingly, our aim was to compare personality changes in Argentinean patients with Alzheimer disease, behavioral variant of frontotemporal dementia, and primary progressive aphasia. The closest living relatives of patients diagnosed with Alzheimer disease (n=19), behavioral variant of frontotemporal dementia (n=16), and primary progressive aphasia (n=15) were asked to complete 2 versions of the personality inventory NEO Personality Inventory-Revised, one for assessing patients' premorbid personality traits, and the other for assessing current traits. All groups showed changes in several domains and facets of the NEO Personality Inventory-Revised. Globally, the observed pattern of changes was fairly consistent with previous studies based on the same model of personality. Nevertheless, our results regarding disease-specificity were less conclusive. Even if there were some indicators of specific differences between groups, most traits varied similarly across the 3 groups, revealing a pattern of generalized changes in personality expression after illness onset. More studies are needed that help to distinguish real personality changes from other affective or cognitive symptoms that accompany dementia, as well as further data from culturally diverse populations.
Fil: Torrente, Fernando. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Universidad Diego Portales; Chile
Fil: Pose, Mariángeles. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Instituto de Neurología Cognitiva; Argentina
Fil: Gleichgerrcht, Ezequiel. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Universidad Diego Portales; Chile. Instituto de Neurología Cognitiva; Argentina
Fil: Torralva, Teresa. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Universidad Diego Portales; Chile. Instituto de Neurología Cognitiva; Argentina
Fil: López, Pablo. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Instituto de Neurología Cognitiva; Argentina
Fil: Cetkovich Bakmas, Marcelo. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina
Fil: Manes, Facundo Francisco. Instituto de Neurología Cognitiva; Argentina. Universidad Diego Portales; Chile. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Alzheimer'S Disease
Dementia
Personality Changes
Neo
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/34891
Acceder
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network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Personality Changes in Dementia: Are They Disease Specific and Universal?Torrente, FernandoPose, MariángelesGleichgerrcht, EzequielTorralva, TeresaLópez, PabloCetkovich Bakmas, MarceloManes, Facundo FranciscoAlzheimer'S DiseaseDementiaPersonality ChangesNeohttps://purl.org/becyt/ford/5.1https://purl.org/becyt/ford/5Previous studies about personality changes in dementia suggest that they may be due to the disruption of the biological basis of personality traits, and hence, that they are disease specific and universal. However, evidence about its specificity is still limited and scarce regarding culturally diverse populations. Accordingly, our aim was to compare personality changes in Argentinean patients with Alzheimer disease, behavioral variant of frontotemporal dementia, and primary progressive aphasia. The closest living relatives of patients diagnosed with Alzheimer disease (n=19), behavioral variant of frontotemporal dementia (n=16), and primary progressive aphasia (n=15) were asked to complete 2 versions of the personality inventory NEO Personality Inventory-Revised, one for assessing patients' premorbid personality traits, and the other for assessing current traits. All groups showed changes in several domains and facets of the NEO Personality Inventory-Revised. Globally, the observed pattern of changes was fairly consistent with previous studies based on the same model of personality. Nevertheless, our results regarding disease-specificity were less conclusive. Even if there were some indicators of specific differences between groups, most traits varied similarly across the 3 groups, revealing a pattern of generalized changes in personality expression after illness onset. More studies are needed that help to distinguish real personality changes from other affective or cognitive symptoms that accompany dementia, as well as further data from culturally diverse populations.Fil: Torrente, Fernando. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Universidad Diego Portales; ChileFil: Pose, Mariángeles. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Instituto de Neurología Cognitiva; ArgentinaFil: Gleichgerrcht, Ezequiel. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Universidad Diego Portales; Chile. Instituto de Neurología Cognitiva; ArgentinaFil: Torralva, Teresa. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Universidad Diego Portales; Chile. Instituto de Neurología Cognitiva; ArgentinaFil: López, Pablo. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Instituto de Neurología Cognitiva; ArgentinaFil: Cetkovich Bakmas, Marcelo. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; ArgentinaFil: Manes, Facundo Francisco. Instituto de Neurología Cognitiva; Argentina. Universidad Diego Portales; Chile. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaLippincott Williams2014-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/mswordapplication/pdfhttp://hdl.handle.net/11336/34891Torrente, Fernando; Pose, Mariángeles; Gleichgerrcht, Ezequiel; Torralva, Teresa; López, Pablo; et al.; Personality Changes in Dementia: Are They Disease Specific and Universal?; Lippincott Williams; Alzheimer Disease & Associated Disorders; 28; 3; 3-2014; 261-2680893-0341CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1097/WAD.0000000000000030info:eu-repo/semantics/altIdentifier/url/https://insights.ovid.com/pubmed?pmid=24614269info:eu-repo/semantics/altIdentifier/url/https://journals.lww.com/alzheimerjournal/pages/articleviewer.aspx?year=2014&issue=07000&article=00009&type=abstractinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2026-02-26T10:01:09Zoai:ri.conicet.gov.ar:11336/34891instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982026-02-26 10:01:09.986CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Personality Changes in Dementia: Are They Disease Specific and Universal?
title Personality Changes in Dementia: Are They Disease Specific and Universal?
spellingShingle Personality Changes in Dementia: Are They Disease Specific and Universal?
Torrente, Fernando
Alzheimer'S Disease
Dementia
Personality Changes
Neo
title_short Personality Changes in Dementia: Are They Disease Specific and Universal?
title_full Personality Changes in Dementia: Are They Disease Specific and Universal?
title_fullStr Personality Changes in Dementia: Are They Disease Specific and Universal?
title_full_unstemmed Personality Changes in Dementia: Are They Disease Specific and Universal?
title_sort Personality Changes in Dementia: Are They Disease Specific and Universal?
dc.creator.none.fl_str_mv Torrente, Fernando
Pose, Mariángeles
Gleichgerrcht, Ezequiel
Torralva, Teresa
López, Pablo
Cetkovich Bakmas, Marcelo
Manes, Facundo Francisco
author Torrente, Fernando
author_facet Torrente, Fernando
Pose, Mariángeles
Gleichgerrcht, Ezequiel
Torralva, Teresa
López, Pablo
Cetkovich Bakmas, Marcelo
Manes, Facundo Francisco
author_role author
author2 Pose, Mariángeles
Gleichgerrcht, Ezequiel
Torralva, Teresa
López, Pablo
Cetkovich Bakmas, Marcelo
Manes, Facundo Francisco
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Alzheimer'S Disease
Dementia
Personality Changes
Neo
topic Alzheimer'S Disease
Dementia
Personality Changes
Neo
purl_subject.fl_str_mv https://purl.org/becyt/ford/5.1
https://purl.org/becyt/ford/5
dc.description.none.fl_txt_mv Previous studies about personality changes in dementia suggest that they may be due to the disruption of the biological basis of personality traits, and hence, that they are disease specific and universal. However, evidence about its specificity is still limited and scarce regarding culturally diverse populations. Accordingly, our aim was to compare personality changes in Argentinean patients with Alzheimer disease, behavioral variant of frontotemporal dementia, and primary progressive aphasia. The closest living relatives of patients diagnosed with Alzheimer disease (n=19), behavioral variant of frontotemporal dementia (n=16), and primary progressive aphasia (n=15) were asked to complete 2 versions of the personality inventory NEO Personality Inventory-Revised, one for assessing patients' premorbid personality traits, and the other for assessing current traits. All groups showed changes in several domains and facets of the NEO Personality Inventory-Revised. Globally, the observed pattern of changes was fairly consistent with previous studies based on the same model of personality. Nevertheless, our results regarding disease-specificity were less conclusive. Even if there were some indicators of specific differences between groups, most traits varied similarly across the 3 groups, revealing a pattern of generalized changes in personality expression after illness onset. More studies are needed that help to distinguish real personality changes from other affective or cognitive symptoms that accompany dementia, as well as further data from culturally diverse populations.
Fil: Torrente, Fernando. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Universidad Diego Portales; Chile
Fil: Pose, Mariángeles. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Instituto de Neurología Cognitiva; Argentina
Fil: Gleichgerrcht, Ezequiel. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Universidad Diego Portales; Chile. Instituto de Neurología Cognitiva; Argentina
Fil: Torralva, Teresa. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Universidad Diego Portales; Chile. Instituto de Neurología Cognitiva; Argentina
Fil: López, Pablo. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Instituto de Neurología Cognitiva; Argentina
Fil: Cetkovich Bakmas, Marcelo. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina
Fil: Manes, Facundo Francisco. Instituto de Neurología Cognitiva; Argentina. Universidad Diego Portales; Chile. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description Previous studies about personality changes in dementia suggest that they may be due to the disruption of the biological basis of personality traits, and hence, that they are disease specific and universal. However, evidence about its specificity is still limited and scarce regarding culturally diverse populations. Accordingly, our aim was to compare personality changes in Argentinean patients with Alzheimer disease, behavioral variant of frontotemporal dementia, and primary progressive aphasia. The closest living relatives of patients diagnosed with Alzheimer disease (n=19), behavioral variant of frontotemporal dementia (n=16), and primary progressive aphasia (n=15) were asked to complete 2 versions of the personality inventory NEO Personality Inventory-Revised, one for assessing patients' premorbid personality traits, and the other for assessing current traits. All groups showed changes in several domains and facets of the NEO Personality Inventory-Revised. Globally, the observed pattern of changes was fairly consistent with previous studies based on the same model of personality. Nevertheless, our results regarding disease-specificity were less conclusive. Even if there were some indicators of specific differences between groups, most traits varied similarly across the 3 groups, revealing a pattern of generalized changes in personality expression after illness onset. More studies are needed that help to distinguish real personality changes from other affective or cognitive symptoms that accompany dementia, as well as further data from culturally diverse populations.
publishDate 2014
dc.date.none.fl_str_mv 2014-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/34891
Torrente, Fernando; Pose, Mariángeles; Gleichgerrcht, Ezequiel; Torralva, Teresa; López, Pablo; et al.; Personality Changes in Dementia: Are They Disease Specific and Universal?; Lippincott Williams; Alzheimer Disease & Associated Disorders; 28; 3; 3-2014; 261-268
0893-0341
CONICET Digital
CONICET
url http://hdl.handle.net/11336/34891
identifier_str_mv Torrente, Fernando; Pose, Mariángeles; Gleichgerrcht, Ezequiel; Torralva, Teresa; López, Pablo; et al.; Personality Changes in Dementia: Are They Disease Specific and Universal?; Lippincott Williams; Alzheimer Disease & Associated Disorders; 28; 3; 3-2014; 261-268
0893-0341
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1097/WAD.0000000000000030
info:eu-repo/semantics/altIdentifier/url/https://insights.ovid.com/pubmed?pmid=24614269
info:eu-repo/semantics/altIdentifier/url/https://journals.lww.com/alzheimerjournal/pages/articleviewer.aspx?year=2014&issue=07000&article=00009&type=abstract
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/msword
application/pdf
dc.publisher.none.fl_str_mv Lippincott Williams
publisher.none.fl_str_mv Lippincott Williams
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.176822

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