Maternal calcium supplementation during pregnancy and dental caries of children at 12 years of age: Follow-up of a randomized controlled trial

Autores
Bergel, Eduardo; Gibbons, Luz; Rasines, María G.; Luetich, Alejandra; Belizan, Jose
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Objectives. To evaluate if calcium supplementation during pregnancy could have any influence on primary dentition measured as the reduction of dental caries of the child. Design. Individual randomized controlled trial. Setting. One hospital in Rosario, Argentina. Population. Random sample of 195 12-year-old children from a follow-up study of 614 women who were randomized during pregnancy to calcium supplementation or placebo. Methods. An independent researcher blinded to the group where the mothers were assigned performed a dental examination of the children. Main outcome measures. Proportion of children with at least one decayed, missing or filled teeth (DMFT/dmft) and mean number of decayed, missing or filled surfaces (DMFS/dmfs) per children. Results. Ninety-eight children were assessed in the calcium supplementation group and 97 in the placebo group. 63.3% of the children whose mother took calcium supplementation had at least one DMFT/dmft compared to 86.6% in the placebo group (<0.001). The children whose mother received the intervention had a 27% reduction in the risk of developing at least one DMFT/dmft (RR: 0.73, CI 95%: [0.62; 0.87]). Conclusions. This study shows a modeling effect of calcium intake during pregnancy on dental caries of the offspring. At around 12 years of age children whose mothers received calcium supplementation when pregnant showed a significant reduction in dental caries.
Fil: Bergel, Eduardo. Organizacion Mundial de la Salud; Argentina
Fil: Gibbons, Luz. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Rasines, María G.. No especifíca;
Fil: Luetich, Alejandra. No especifíca;
Fil: Belizan, Jose. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
CALCIUM INTAKE
DENTAL CARIES
FETAL MODELING
PREGNANCY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/199303
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/199303
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Maternal calcium supplementation during pregnancy and dental caries of children at 12 years of age: Follow-up of a randomized controlled trialBergel, EduardoGibbons, LuzRasines, María G.Luetich, AlejandraBelizan, JoseCALCIUM INTAKEDENTAL CARIESFETAL MODELINGPREGNANCYhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Objectives. To evaluate if calcium supplementation during pregnancy could have any influence on primary dentition measured as the reduction of dental caries of the child. Design. Individual randomized controlled trial. Setting. One hospital in Rosario, Argentina. Population. Random sample of 195 12-year-old children from a follow-up study of 614 women who were randomized during pregnancy to calcium supplementation or placebo. Methods. An independent researcher blinded to the group where the mothers were assigned performed a dental examination of the children. Main outcome measures. Proportion of children with at least one decayed, missing or filled teeth (DMFT/dmft) and mean number of decayed, missing or filled surfaces (DMFS/dmfs) per children. Results. Ninety-eight children were assessed in the calcium supplementation group and 97 in the placebo group. 63.3% of the children whose mother took calcium supplementation had at least one DMFT/dmft compared to 86.6% in the placebo group (<0.001). The children whose mother received the intervention had a 27% reduction in the risk of developing at least one DMFT/dmft (RR: 0.73, CI 95%: [0.62; 0.87]). Conclusions. This study shows a modeling effect of calcium intake during pregnancy on dental caries of the offspring. At around 12 years of age children whose mothers received calcium supplementation when pregnant showed a significant reduction in dental caries.Fil: Bergel, Eduardo. Organizacion Mundial de la Salud; ArgentinaFil: Gibbons, Luz. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Rasines, María G.. No especifíca;Fil: Luetich, Alejandra. No especifíca;Fil: Belizan, Jose. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaTaylor & Francis As2010-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/octet-streamapplication/pdfhttp://hdl.handle.net/11336/199303Bergel, Eduardo; Gibbons, Luz; Rasines, María G.; Luetich, Alejandra; Belizan, Jose; Maternal calcium supplementation during pregnancy and dental caries of children at 12 years of age: Follow-up of a randomized controlled trial; Taylor & Francis As; Acta Obstetricia And Gynecologica Scandinavica; 89; 11; 11-2010; 1396-14020001-6349CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://obgyn.onlinelibrary.wiley.com/doi/10.3109/00016349.2010.518228info:eu-repo/semantics/altIdentifier/doi/10.3109/00016349.2010.518228info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:14:01Zoai:ri.conicet.gov.ar:11336/199303instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:14:01.34CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Maternal calcium supplementation during pregnancy and dental caries of children at 12 years of age: Follow-up of a randomized controlled trial
title Maternal calcium supplementation during pregnancy and dental caries of children at 12 years of age: Follow-up of a randomized controlled trial
spellingShingle Maternal calcium supplementation during pregnancy and dental caries of children at 12 years of age: Follow-up of a randomized controlled trial
Bergel, Eduardo
CALCIUM INTAKE
DENTAL CARIES
FETAL MODELING
PREGNANCY
title_short Maternal calcium supplementation during pregnancy and dental caries of children at 12 years of age: Follow-up of a randomized controlled trial
title_full Maternal calcium supplementation during pregnancy and dental caries of children at 12 years of age: Follow-up of a randomized controlled trial
title_fullStr Maternal calcium supplementation during pregnancy and dental caries of children at 12 years of age: Follow-up of a randomized controlled trial
title_full_unstemmed Maternal calcium supplementation during pregnancy and dental caries of children at 12 years of age: Follow-up of a randomized controlled trial
title_sort Maternal calcium supplementation during pregnancy and dental caries of children at 12 years of age: Follow-up of a randomized controlled trial
dc.creator.none.fl_str_mv Bergel, Eduardo
Gibbons, Luz
Rasines, María G.
Luetich, Alejandra
Belizan, Jose
author Bergel, Eduardo
author_facet Bergel, Eduardo
Gibbons, Luz
Rasines, María G.
Luetich, Alejandra
Belizan, Jose
author_role author
author2 Gibbons, Luz
Rasines, María G.
Luetich, Alejandra
Belizan, Jose
author2_role author
author
author
author
dc.subject.none.fl_str_mv CALCIUM INTAKE
DENTAL CARIES
FETAL MODELING
PREGNANCY
topic CALCIUM INTAKE
DENTAL CARIES
FETAL MODELING
PREGNANCY
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Objectives. To evaluate if calcium supplementation during pregnancy could have any influence on primary dentition measured as the reduction of dental caries of the child. Design. Individual randomized controlled trial. Setting. One hospital in Rosario, Argentina. Population. Random sample of 195 12-year-old children from a follow-up study of 614 women who were randomized during pregnancy to calcium supplementation or placebo. Methods. An independent researcher blinded to the group where the mothers were assigned performed a dental examination of the children. Main outcome measures. Proportion of children with at least one decayed, missing or filled teeth (DMFT/dmft) and mean number of decayed, missing or filled surfaces (DMFS/dmfs) per children. Results. Ninety-eight children were assessed in the calcium supplementation group and 97 in the placebo group. 63.3% of the children whose mother took calcium supplementation had at least one DMFT/dmft compared to 86.6% in the placebo group (<0.001). The children whose mother received the intervention had a 27% reduction in the risk of developing at least one DMFT/dmft (RR: 0.73, CI 95%: [0.62; 0.87]). Conclusions. This study shows a modeling effect of calcium intake during pregnancy on dental caries of the offspring. At around 12 years of age children whose mothers received calcium supplementation when pregnant showed a significant reduction in dental caries.
Fil: Bergel, Eduardo. Organizacion Mundial de la Salud; Argentina
Fil: Gibbons, Luz. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Rasines, María G.. No especifíca;
Fil: Luetich, Alejandra. No especifíca;
Fil: Belizan, Jose. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description Objectives. To evaluate if calcium supplementation during pregnancy could have any influence on primary dentition measured as the reduction of dental caries of the child. Design. Individual randomized controlled trial. Setting. One hospital in Rosario, Argentina. Population. Random sample of 195 12-year-old children from a follow-up study of 614 women who were randomized during pregnancy to calcium supplementation or placebo. Methods. An independent researcher blinded to the group where the mothers were assigned performed a dental examination of the children. Main outcome measures. Proportion of children with at least one decayed, missing or filled teeth (DMFT/dmft) and mean number of decayed, missing or filled surfaces (DMFS/dmfs) per children. Results. Ninety-eight children were assessed in the calcium supplementation group and 97 in the placebo group. 63.3% of the children whose mother took calcium supplementation had at least one DMFT/dmft compared to 86.6% in the placebo group (<0.001). The children whose mother received the intervention had a 27% reduction in the risk of developing at least one DMFT/dmft (RR: 0.73, CI 95%: [0.62; 0.87]). Conclusions. This study shows a modeling effect of calcium intake during pregnancy on dental caries of the offspring. At around 12 years of age children whose mothers received calcium supplementation when pregnant showed a significant reduction in dental caries.
publishDate 2010
dc.date.none.fl_str_mv 2010-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/199303
Bergel, Eduardo; Gibbons, Luz; Rasines, María G.; Luetich, Alejandra; Belizan, Jose; Maternal calcium supplementation during pregnancy and dental caries of children at 12 years of age: Follow-up of a randomized controlled trial; Taylor & Francis As; Acta Obstetricia And Gynecologica Scandinavica; 89; 11; 11-2010; 1396-1402
0001-6349
CONICET Digital
CONICET
url http://hdl.handle.net/11336/199303
identifier_str_mv Bergel, Eduardo; Gibbons, Luz; Rasines, María G.; Luetich, Alejandra; Belizan, Jose; Maternal calcium supplementation during pregnancy and dental caries of children at 12 years of age: Follow-up of a randomized controlled trial; Taylor & Francis As; Acta Obstetricia And Gynecologica Scandinavica; 89; 11; 11-2010; 1396-1402
0001-6349
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://obgyn.onlinelibrary.wiley.com/doi/10.3109/00016349.2010.518228
info:eu-repo/semantics/altIdentifier/doi/10.3109/00016349.2010.518228
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/octet-stream
application/pdf
dc.publisher.none.fl_str_mv Taylor & Francis As
publisher.none.fl_str_mv Taylor & Francis As
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846781555747323904
score 12.982451

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