Ghrelin and memory: Differential effects on acquisition and retrieval

Autores
Carlini, Valeria Paola; Ghersi, Marisa Soledad; Schiöth, Helgi Birgir; de Barioglio, Susana Rubiales
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In a previous paper we have demonstrated that the orexigenic peptide Ghrelin (Ghr), increases memory retention in rats and mice. In the present work we evaluated the Ghr effect when it was administered previous the training session or previous the test session (24 h after training) on the memory performance, using step-down test. The results showed that the intra-hippocampal Ghr administration previous the training session improved the long-term memory in this task, but did not modify the short-term memory. Nevertheless, when the Ghr was administrated previous the test session, no changes were observed in the memory performance. Taking into account these results and other previously published by our group, we could hypothesizes that Ghr may modulate specific molecular intermediates involved in memory acquisition/consolidation but not in the retrieval.
Fil: Carlini, Valeria Paola. Universidad Nacional de Córdoba. Facultad de Cs.químicas. Departamento de Farmacología. Cátedra de Fisiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Ghersi, Marisa Soledad. Universidad Nacional de Córdoba. Facultad de Cs.químicas. Departamento de Farmacología. Cátedra de Fisiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Schiöth, Helgi Birgir. Uppsala Universitet; Suecia
Fil: de Barioglio, Susana Rubiales. Universidad Nacional de Córdoba. Facultad de Cs.químicas. Departamento de Farmacología. Cátedra de Fisiología; Argentina
Materia
GHRELIN
LONG-TERM MEMORY
MEMORY ACQUISITION
MEMORY RETENTION
SHORT-TERM MEMORY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/130466
Acceder
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network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Ghrelin and memory: Differential effects on acquisition and retrievalCarlini, Valeria PaolaGhersi, Marisa SoledadSchiöth, Helgi Birgirde Barioglio, Susana RubialesGHRELINLONG-TERM MEMORYMEMORY ACQUISITIONMEMORY RETENTIONSHORT-TERM MEMORYhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3In a previous paper we have demonstrated that the orexigenic peptide Ghrelin (Ghr), increases memory retention in rats and mice. In the present work we evaluated the Ghr effect when it was administered previous the training session or previous the test session (24 h after training) on the memory performance, using step-down test. The results showed that the intra-hippocampal Ghr administration previous the training session improved the long-term memory in this task, but did not modify the short-term memory. Nevertheless, when the Ghr was administrated previous the test session, no changes were observed in the memory performance. Taking into account these results and other previously published by our group, we could hypothesizes that Ghr may modulate specific molecular intermediates involved in memory acquisition/consolidation but not in the retrieval.Fil: Carlini, Valeria Paola. Universidad Nacional de Córdoba. Facultad de Cs.químicas. Departamento de Farmacología. Cátedra de Fisiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Ghersi, Marisa Soledad. Universidad Nacional de Córdoba. Facultad de Cs.químicas. Departamento de Farmacología. Cátedra de Fisiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Schiöth, Helgi Birgir. Uppsala Universitet; SueciaFil: de Barioglio, Susana Rubiales. Universidad Nacional de Córdoba. Facultad de Cs.químicas. Departamento de Farmacología. Cátedra de Fisiología; ArgentinaElsevier Science Inc2010-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/130466Carlini, Valeria Paola; Ghersi, Marisa Soledad; Schiöth, Helgi Birgir; de Barioglio, Susana Rubiales; Ghrelin and memory: Differential effects on acquisition and retrieval; Elsevier Science Inc; Peptides; 31; 6; 6-2010; 1190-11930196-9781CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0196978110000938info:eu-repo/semantics/altIdentifier/doi/10.1016/j.peptides.2010.02.021info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:11:07Zoai:ri.conicet.gov.ar:11336/130466instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:11:07.88CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Ghrelin and memory: Differential effects on acquisition and retrieval
title Ghrelin and memory: Differential effects on acquisition and retrieval
spellingShingle Ghrelin and memory: Differential effects on acquisition and retrieval
Carlini, Valeria Paola
GHRELIN
LONG-TERM MEMORY
MEMORY ACQUISITION
MEMORY RETENTION
SHORT-TERM MEMORY
title_short Ghrelin and memory: Differential effects on acquisition and retrieval
title_full Ghrelin and memory: Differential effects on acquisition and retrieval
title_fullStr Ghrelin and memory: Differential effects on acquisition and retrieval
title_full_unstemmed Ghrelin and memory: Differential effects on acquisition and retrieval
title_sort Ghrelin and memory: Differential effects on acquisition and retrieval
dc.creator.none.fl_str_mv Carlini, Valeria Paola
Ghersi, Marisa Soledad
Schiöth, Helgi Birgir
de Barioglio, Susana Rubiales
author Carlini, Valeria Paola
author_facet Carlini, Valeria Paola
Ghersi, Marisa Soledad
Schiöth, Helgi Birgir
de Barioglio, Susana Rubiales
author_role author
author2 Ghersi, Marisa Soledad
Schiöth, Helgi Birgir
de Barioglio, Susana Rubiales
author2_role author
author
author
dc.subject.none.fl_str_mv GHRELIN
LONG-TERM MEMORY
MEMORY ACQUISITION
MEMORY RETENTION
SHORT-TERM MEMORY
topic GHRELIN
LONG-TERM MEMORY
MEMORY ACQUISITION
MEMORY RETENTION
SHORT-TERM MEMORY
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv In a previous paper we have demonstrated that the orexigenic peptide Ghrelin (Ghr), increases memory retention in rats and mice. In the present work we evaluated the Ghr effect when it was administered previous the training session or previous the test session (24 h after training) on the memory performance, using step-down test. The results showed that the intra-hippocampal Ghr administration previous the training session improved the long-term memory in this task, but did not modify the short-term memory. Nevertheless, when the Ghr was administrated previous the test session, no changes were observed in the memory performance. Taking into account these results and other previously published by our group, we could hypothesizes that Ghr may modulate specific molecular intermediates involved in memory acquisition/consolidation but not in the retrieval.
Fil: Carlini, Valeria Paola. Universidad Nacional de Córdoba. Facultad de Cs.químicas. Departamento de Farmacología. Cátedra de Fisiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Ghersi, Marisa Soledad. Universidad Nacional de Córdoba. Facultad de Cs.químicas. Departamento de Farmacología. Cátedra de Fisiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Schiöth, Helgi Birgir. Uppsala Universitet; Suecia
Fil: de Barioglio, Susana Rubiales. Universidad Nacional de Córdoba. Facultad de Cs.químicas. Departamento de Farmacología. Cátedra de Fisiología; Argentina
description In a previous paper we have demonstrated that the orexigenic peptide Ghrelin (Ghr), increases memory retention in rats and mice. In the present work we evaluated the Ghr effect when it was administered previous the training session or previous the test session (24 h after training) on the memory performance, using step-down test. The results showed that the intra-hippocampal Ghr administration previous the training session improved the long-term memory in this task, but did not modify the short-term memory. Nevertheless, when the Ghr was administrated previous the test session, no changes were observed in the memory performance. Taking into account these results and other previously published by our group, we could hypothesizes that Ghr may modulate specific molecular intermediates involved in memory acquisition/consolidation but not in the retrieval.
publishDate 2010
dc.date.none.fl_str_mv 2010-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/130466
Carlini, Valeria Paola; Ghersi, Marisa Soledad; Schiöth, Helgi Birgir; de Barioglio, Susana Rubiales; Ghrelin and memory: Differential effects on acquisition and retrieval; Elsevier Science Inc; Peptides; 31; 6; 6-2010; 1190-1193
0196-9781
CONICET Digital
CONICET
url http://hdl.handle.net/11336/130466
identifier_str_mv Carlini, Valeria Paola; Ghersi, Marisa Soledad; Schiöth, Helgi Birgir; de Barioglio, Susana Rubiales; Ghrelin and memory: Differential effects on acquisition and retrieval; Elsevier Science Inc; Peptides; 31; 6; 6-2010; 1190-1193
0196-9781
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0196978110000938
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.peptides.2010.02.021
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science Inc
publisher.none.fl_str_mv Elsevier Science Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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