The chemical compositions of essential oils derived from cryptocarya alba and laurelia sempervirens possess antioxidant, antibacterial and antitumoral activity potential

Autores
Touma, Jorge; Navarro, Myriam; Sepúlveda, Betsabet; Pavon, Alequis; Corsini, Gino; Fernández, Katia; Quezada, Claudia; Torres, Angelo; Larrazabal Fuentes, María José; Paredes, Adrian; Neira, Ivan; Ferrando, Matías; Bruna, Flavia Alejandra; Venegas, Alejandro; Bravo, Jessica
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Cryptocarya alba (Peumo; CA) and Laurelia sempervirens (Laurel; LS) are herbs native to the Chilean highlands and have historically been used for medicinal purposes by the Huilliches people. In this work, the essential oils were extracted using hydrodistillation in Clevenger apparatus and analyzed by GC-MS to determine their composition. The antioxidant capacity (AC) was evaluated in vitro. The cytotoxicity was determined using cell line cultures both non tumoral and tumoral. The toxicity was determined using the nematode Caenorhabditis elegans. The antimicrobial activity was evaluated against 52 bacteria using the agar disc diffusion method and the minimum inhibitory concentrations (MICs) were determined. The principal compounds found in C. alba essential oil (CA_EO) were α-terpineol (24.96%) and eucalyptol (21.63%) and were isazafrol (91.9%) in L. sempervirens essential oil (LS_EO). Both EOs showed antioxidant capacity in vitro. Both EO showed antibacterial activity against bacteria using. LS_EO showed more inhibitory effect on these cell lines respect to CA_EO. Both EOs showed toxicity against the nematode C. elegans at 3.12–50 mg/mL. The essential oils of CA and LS have an important bioactive potential in their antioxidant, antibacterial and cytotoxicity activity. Both essential oils could possibly be used in the field of natural medicine, natural food preservation, cosmetics, sanitation and plaguicides among others.
Fil: Touma, Jorge. Universidad Diego Portales; Chile
Fil: Navarro, Myriam. Universidad Diego Portales; Chile
Fil: Sepúlveda, Betsabet. Universidad de Chile; Chile
Fil: Pavon, Alequis. Universidad Autónoma de Chile; Chile
Fil: Corsini, Gino. Universidad Autónoma de Chile; Chile
Fil: Fernández, Katia. Universidad Diego Portales; Chile
Fil: Quezada, Claudia. Universidad Austral de Chile; Chile
Fil: Torres, Angelo. Universidad Austral de Chile; Chile
Fil: Larrazabal Fuentes, María José. Universidad de Antofagasta; Chile
Fil: Paredes, Adrian. Universidad de Antofagasta; Chile
Fil: Neira, Ivan. Universidad de Antofagasta; Chile
Fil: Ferrando, Matías. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina
Fil: Bruna, Flavia Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina
Fil: Venegas, Alejandro. Universidad Diego Portales; Chile
Fil: Bravo, Jessica. Universidad Diego Portales; Chile
Materia
ANTIMICROBIAL
ANTIOXIDANT
CHEMICAL COMPOSITION
CRYPTOCARYA ALBA
CYTOXICITY
ESSENTIAL OIL
LAURELIA SEMPERVIRENS
TOXICITY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/142043
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/142043
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling The chemical compositions of essential oils derived from cryptocarya alba and laurelia sempervirens possess antioxidant, antibacterial and antitumoral activity potentialTouma, JorgeNavarro, MyriamSepúlveda, BetsabetPavon, AlequisCorsini, GinoFernández, KatiaQuezada, ClaudiaTorres, AngeloLarrazabal Fuentes, María JoséParedes, AdrianNeira, IvanFerrando, MatíasBruna, Flavia AlejandraVenegas, AlejandroBravo, JessicaANTIMICROBIALANTIOXIDANTCHEMICAL COMPOSITIONCRYPTOCARYA ALBACYTOXICITYESSENTIAL OILLAURELIA SEMPERVIRENSTOXICITYhttps://purl.org/becyt/ford/3.5https://purl.org/becyt/ford/3Cryptocarya alba (Peumo; CA) and Laurelia sempervirens (Laurel; LS) are herbs native to the Chilean highlands and have historically been used for medicinal purposes by the Huilliches people. In this work, the essential oils were extracted using hydrodistillation in Clevenger apparatus and analyzed by GC-MS to determine their composition. The antioxidant capacity (AC) was evaluated in vitro. The cytotoxicity was determined using cell line cultures both non tumoral and tumoral. The toxicity was determined using the nematode Caenorhabditis elegans. The antimicrobial activity was evaluated against 52 bacteria using the agar disc diffusion method and the minimum inhibitory concentrations (MICs) were determined. The principal compounds found in C. alba essential oil (CA_EO) were α-terpineol (24.96%) and eucalyptol (21.63%) and were isazafrol (91.9%) in L. sempervirens essential oil (LS_EO). Both EOs showed antioxidant capacity in vitro. Both EO showed antibacterial activity against bacteria using. LS_EO showed more inhibitory effect on these cell lines respect to CA_EO. Both EOs showed toxicity against the nematode C. elegans at 3.12–50 mg/mL. The essential oils of CA and LS have an important bioactive potential in their antioxidant, antibacterial and cytotoxicity activity. Both essential oils could possibly be used in the field of natural medicine, natural food preservation, cosmetics, sanitation and plaguicides among others.Fil: Touma, Jorge. Universidad Diego Portales; ChileFil: Navarro, Myriam. Universidad Diego Portales; ChileFil: Sepúlveda, Betsabet. Universidad de Chile; ChileFil: Pavon, Alequis. Universidad Autónoma de Chile; ChileFil: Corsini, Gino. Universidad Autónoma de Chile; ChileFil: Fernández, Katia. Universidad Diego Portales; ChileFil: Quezada, Claudia. Universidad Austral de Chile; ChileFil: Torres, Angelo. Universidad Austral de Chile; ChileFil: Larrazabal Fuentes, María José. Universidad de Antofagasta; ChileFil: Paredes, Adrian. Universidad de Antofagasta; ChileFil: Neira, Ivan. Universidad de Antofagasta; ChileFil: Ferrando, Matías. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; ArgentinaFil: Bruna, Flavia Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; ArgentinaFil: Venegas, Alejandro. Universidad Diego Portales; ChileFil: Bravo, Jessica. Universidad Diego Portales; ChileMolecular Diversity Preservation International2020-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/142043Touma, Jorge; Navarro, Myriam; Sepúlveda, Betsabet; Pavon, Alequis; Corsini, Gino; et al.; The chemical compositions of essential oils derived from cryptocarya alba and laurelia sempervirens possess antioxidant, antibacterial and antitumoral activity potential; Molecular Diversity Preservation International; Molecules; 25; 23; 11-2020; 1-171420-3049CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/1420-3049/25/23/5600info:eu-repo/semantics/altIdentifier/doi/10.3390/molecules25235600info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:08:05Zoai:ri.conicet.gov.ar:11336/142043instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:08:05.358CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv The chemical compositions of essential oils derived from cryptocarya alba and laurelia sempervirens possess antioxidant, antibacterial and antitumoral activity potential
title The chemical compositions of essential oils derived from cryptocarya alba and laurelia sempervirens possess antioxidant, antibacterial and antitumoral activity potential
spellingShingle The chemical compositions of essential oils derived from cryptocarya alba and laurelia sempervirens possess antioxidant, antibacterial and antitumoral activity potential
Touma, Jorge
ANTIMICROBIAL
ANTIOXIDANT
CHEMICAL COMPOSITION
CRYPTOCARYA ALBA
CYTOXICITY
ESSENTIAL OIL
LAURELIA SEMPERVIRENS
TOXICITY
title_short The chemical compositions of essential oils derived from cryptocarya alba and laurelia sempervirens possess antioxidant, antibacterial and antitumoral activity potential
title_full The chemical compositions of essential oils derived from cryptocarya alba and laurelia sempervirens possess antioxidant, antibacterial and antitumoral activity potential
title_fullStr The chemical compositions of essential oils derived from cryptocarya alba and laurelia sempervirens possess antioxidant, antibacterial and antitumoral activity potential
title_full_unstemmed The chemical compositions of essential oils derived from cryptocarya alba and laurelia sempervirens possess antioxidant, antibacterial and antitumoral activity potential
title_sort The chemical compositions of essential oils derived from cryptocarya alba and laurelia sempervirens possess antioxidant, antibacterial and antitumoral activity potential
dc.creator.none.fl_str_mv Touma, Jorge
Navarro, Myriam
Sepúlveda, Betsabet
Pavon, Alequis
Corsini, Gino
Fernández, Katia
Quezada, Claudia
Torres, Angelo
Larrazabal Fuentes, María José
Paredes, Adrian
Neira, Ivan
Ferrando, Matías
Bruna, Flavia Alejandra
Venegas, Alejandro
Bravo, Jessica
author Touma, Jorge
author_facet Touma, Jorge
Navarro, Myriam
Sepúlveda, Betsabet
Pavon, Alequis
Corsini, Gino
Fernández, Katia
Quezada, Claudia
Torres, Angelo
Larrazabal Fuentes, María José
Paredes, Adrian
Neira, Ivan
Ferrando, Matías
Bruna, Flavia Alejandra
Venegas, Alejandro
Bravo, Jessica
author_role author
author2 Navarro, Myriam
Sepúlveda, Betsabet
Pavon, Alequis
Corsini, Gino
Fernández, Katia
Quezada, Claudia
Torres, Angelo
Larrazabal Fuentes, María José
Paredes, Adrian
Neira, Ivan
Ferrando, Matías
Bruna, Flavia Alejandra
Venegas, Alejandro
Bravo, Jessica
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv ANTIMICROBIAL
ANTIOXIDANT
CHEMICAL COMPOSITION
CRYPTOCARYA ALBA
CYTOXICITY
ESSENTIAL OIL
LAURELIA SEMPERVIRENS
TOXICITY
topic ANTIMICROBIAL
ANTIOXIDANT
CHEMICAL COMPOSITION
CRYPTOCARYA ALBA
CYTOXICITY
ESSENTIAL OIL
LAURELIA SEMPERVIRENS
TOXICITY
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.5
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Cryptocarya alba (Peumo; CA) and Laurelia sempervirens (Laurel; LS) are herbs native to the Chilean highlands and have historically been used for medicinal purposes by the Huilliches people. In this work, the essential oils were extracted using hydrodistillation in Clevenger apparatus and analyzed by GC-MS to determine their composition. The antioxidant capacity (AC) was evaluated in vitro. The cytotoxicity was determined using cell line cultures both non tumoral and tumoral. The toxicity was determined using the nematode Caenorhabditis elegans. The antimicrobial activity was evaluated against 52 bacteria using the agar disc diffusion method and the minimum inhibitory concentrations (MICs) were determined. The principal compounds found in C. alba essential oil (CA_EO) were α-terpineol (24.96%) and eucalyptol (21.63%) and were isazafrol (91.9%) in L. sempervirens essential oil (LS_EO). Both EOs showed antioxidant capacity in vitro. Both EO showed antibacterial activity against bacteria using. LS_EO showed more inhibitory effect on these cell lines respect to CA_EO. Both EOs showed toxicity against the nematode C. elegans at 3.12–50 mg/mL. The essential oils of CA and LS have an important bioactive potential in their antioxidant, antibacterial and cytotoxicity activity. Both essential oils could possibly be used in the field of natural medicine, natural food preservation, cosmetics, sanitation and plaguicides among others.
Fil: Touma, Jorge. Universidad Diego Portales; Chile
Fil: Navarro, Myriam. Universidad Diego Portales; Chile
Fil: Sepúlveda, Betsabet. Universidad de Chile; Chile
Fil: Pavon, Alequis. Universidad Autónoma de Chile; Chile
Fil: Corsini, Gino. Universidad Autónoma de Chile; Chile
Fil: Fernández, Katia. Universidad Diego Portales; Chile
Fil: Quezada, Claudia. Universidad Austral de Chile; Chile
Fil: Torres, Angelo. Universidad Austral de Chile; Chile
Fil: Larrazabal Fuentes, María José. Universidad de Antofagasta; Chile
Fil: Paredes, Adrian. Universidad de Antofagasta; Chile
Fil: Neira, Ivan. Universidad de Antofagasta; Chile
Fil: Ferrando, Matías. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina
Fil: Bruna, Flavia Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina
Fil: Venegas, Alejandro. Universidad Diego Portales; Chile
Fil: Bravo, Jessica. Universidad Diego Portales; Chile
description Cryptocarya alba (Peumo; CA) and Laurelia sempervirens (Laurel; LS) are herbs native to the Chilean highlands and have historically been used for medicinal purposes by the Huilliches people. In this work, the essential oils were extracted using hydrodistillation in Clevenger apparatus and analyzed by GC-MS to determine their composition. The antioxidant capacity (AC) was evaluated in vitro. The cytotoxicity was determined using cell line cultures both non tumoral and tumoral. The toxicity was determined using the nematode Caenorhabditis elegans. The antimicrobial activity was evaluated against 52 bacteria using the agar disc diffusion method and the minimum inhibitory concentrations (MICs) were determined. The principal compounds found in C. alba essential oil (CA_EO) were α-terpineol (24.96%) and eucalyptol (21.63%) and were isazafrol (91.9%) in L. sempervirens essential oil (LS_EO). Both EOs showed antioxidant capacity in vitro. Both EO showed antibacterial activity against bacteria using. LS_EO showed more inhibitory effect on these cell lines respect to CA_EO. Both EOs showed toxicity against the nematode C. elegans at 3.12–50 mg/mL. The essential oils of CA and LS have an important bioactive potential in their antioxidant, antibacterial and cytotoxicity activity. Both essential oils could possibly be used in the field of natural medicine, natural food preservation, cosmetics, sanitation and plaguicides among others.
publishDate 2020
dc.date.none.fl_str_mv 2020-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/142043
Touma, Jorge; Navarro, Myriam; Sepúlveda, Betsabet; Pavon, Alequis; Corsini, Gino; et al.; The chemical compositions of essential oils derived from cryptocarya alba and laurelia sempervirens possess antioxidant, antibacterial and antitumoral activity potential; Molecular Diversity Preservation International; Molecules; 25; 23; 11-2020; 1-17
1420-3049
CONICET Digital
CONICET
url http://hdl.handle.net/11336/142043
identifier_str_mv Touma, Jorge; Navarro, Myriam; Sepúlveda, Betsabet; Pavon, Alequis; Corsini, Gino; et al.; The chemical compositions of essential oils derived from cryptocarya alba and laurelia sempervirens possess antioxidant, antibacterial and antitumoral activity potential; Molecular Diversity Preservation International; Molecules; 25; 23; 11-2020; 1-17
1420-3049
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/1420-3049/25/23/5600
info:eu-repo/semantics/altIdentifier/doi/10.3390/molecules25235600
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Molecular Diversity Preservation International
publisher.none.fl_str_mv Molecular Diversity Preservation International
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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