Autophagic clearance of bacterial pathogens: molecular recognition of intracellular microorganisms

Autores
Mansilla Pareja, MARIA EUGENIA; Colombo, Maria Isabel
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Autophagy is involved in several physiological and pathological processes. One of the key roles of the autophagic pathway is to participate in the first line of defense against the invasion of pathogens, as part of the innate immune response. Targeting of intracellular bacteria by the autophagic machinery, either in the cytoplasm or within vacuolar compartments, helps to control bacterial proliferation in the host cell, controlling also the spreading of the infection. In this review we will describe the means used by diverse bacterial pathogens to survive intracellularly and how they are recognized by the autophagic molecular machinery, as well as the mechanisms used to avoid autophagic clearance.
Fil: Mansilla Pareja, MARIA EUGENIA. Consejo Nacional de Investigaciones Cientiâ­ficas y Tecnicas. Centro Cientifico Tecnologico Mendoza. Instituto Histologia y Embriologia de Mendoza "dr. M. Burgos"; Argentina
Fil: Colombo, Maria Isabel. Consejo Nacional de Investigaciones Cientiâ­ficas y Tecnicas. Centro Cientifico Tecnologico Mendoza. Instituto Histologia y Embriologia de Mendoza "dr. M. Burgos"; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina
Materia
AUTOPHAGY
INTRACELLULAR BACTERIA
PATHOGENS
PHAGOCYTOSIS
INTRACELLULAR PAHTOGENS
RECOGNITION
XENOPHAGY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
Atribución-NoComercial-CompartirIgual 2.5 Argentina (CC BY-NC-SA 2.5 AR)
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/9830
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Autophagic clearance of bacterial pathogens: molecular recognition of intracellular microorganismsMansilla Pareja, MARIA EUGENIAColombo, Maria IsabelAUTOPHAGYINTRACELLULAR BACTERIAPATHOGENSPHAGOCYTOSISINTRACELLULAR PAHTOGENSRECOGNITIONXENOPHAGYhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Autophagy is involved in several physiological and pathological processes. One of the key roles of the autophagic pathway is to participate in the first line of defense against the invasion of pathogens, as part of the innate immune response. Targeting of intracellular bacteria by the autophagic machinery, either in the cytoplasm or within vacuolar compartments, helps to control bacterial proliferation in the host cell, controlling also the spreading of the infection. In this review we will describe the means used by diverse bacterial pathogens to survive intracellularly and how they are recognized by the autophagic molecular machinery, as well as the mechanisms used to avoid autophagic clearance.Fil: Mansilla Pareja, MARIA EUGENIA. Consejo Nacional de Investigaciones Cientiâ­ficas y Tecnicas. Centro Cientifico Tecnologico Mendoza. Instituto Histologia y Embriologia de Mendoza "dr. M. Burgos"; ArgentinaFil: Colombo, Maria Isabel. Consejo Nacional de Investigaciones Cientiâ­ficas y Tecnicas. Centro Cientifico Tecnologico Mendoza. Instituto Histologia y Embriologia de Mendoza "dr. M. Burgos"; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; ArgentinaFrontiers2013-09-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/9830Mansilla Pareja, MARIA EUGENIA; Colombo, Maria Isabel; Autophagic clearance of bacterial pathogens: molecular recognition of intracellular microorganisms; Frontiers; Frontiers in Cellular and Infection Microbiology; 3; 54; 30-9-2013; 1-142235-2988enginfo:eu-repo/semantics/altIdentifier/url/http://dx.doi.org/10.3389/fcimb.2013.00054info:eu-repo/semantics/altIdentifier/url/http://journal.frontiersin.org/article/10.3389/fcimb.2013.00054info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786225/info:eu-repo/semantics/openAccessAtribución-NoComercial-CompartirIgual 2.5 Argentina (CC BY-NC-SA 2.5 AR)https://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:04:26Zoai:ri.conicet.gov.ar:11336/9830instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:04:27.087CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Autophagic clearance of bacterial pathogens: molecular recognition of intracellular microorganisms
title Autophagic clearance of bacterial pathogens: molecular recognition of intracellular microorganisms
spellingShingle Autophagic clearance of bacterial pathogens: molecular recognition of intracellular microorganisms
Mansilla Pareja, MARIA EUGENIA
AUTOPHAGY
INTRACELLULAR BACTERIA
PATHOGENS
PHAGOCYTOSIS
INTRACELLULAR PAHTOGENS
RECOGNITION
XENOPHAGY
title_short Autophagic clearance of bacterial pathogens: molecular recognition of intracellular microorganisms
title_full Autophagic clearance of bacterial pathogens: molecular recognition of intracellular microorganisms
title_fullStr Autophagic clearance of bacterial pathogens: molecular recognition of intracellular microorganisms
title_full_unstemmed Autophagic clearance of bacterial pathogens: molecular recognition of intracellular microorganisms
title_sort Autophagic clearance of bacterial pathogens: molecular recognition of intracellular microorganisms
dc.creator.none.fl_str_mv Mansilla Pareja, MARIA EUGENIA
Colombo, Maria Isabel
author Mansilla Pareja, MARIA EUGENIA
author_facet Mansilla Pareja, MARIA EUGENIA
Colombo, Maria Isabel
author_role author
author2 Colombo, Maria Isabel
author2_role author
dc.subject.none.fl_str_mv AUTOPHAGY
INTRACELLULAR BACTERIA
PATHOGENS
PHAGOCYTOSIS
INTRACELLULAR PAHTOGENS
RECOGNITION
XENOPHAGY
topic AUTOPHAGY
INTRACELLULAR BACTERIA
PATHOGENS
PHAGOCYTOSIS
INTRACELLULAR PAHTOGENS
RECOGNITION
XENOPHAGY
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Autophagy is involved in several physiological and pathological processes. One of the key roles of the autophagic pathway is to participate in the first line of defense against the invasion of pathogens, as part of the innate immune response. Targeting of intracellular bacteria by the autophagic machinery, either in the cytoplasm or within vacuolar compartments, helps to control bacterial proliferation in the host cell, controlling also the spreading of the infection. In this review we will describe the means used by diverse bacterial pathogens to survive intracellularly and how they are recognized by the autophagic molecular machinery, as well as the mechanisms used to avoid autophagic clearance.
Fil: Mansilla Pareja, MARIA EUGENIA. Consejo Nacional de Investigaciones Cientiâ­ficas y Tecnicas. Centro Cientifico Tecnologico Mendoza. Instituto Histologia y Embriologia de Mendoza "dr. M. Burgos"; Argentina
Fil: Colombo, Maria Isabel. Consejo Nacional de Investigaciones Cientiâ­ficas y Tecnicas. Centro Cientifico Tecnologico Mendoza. Instituto Histologia y Embriologia de Mendoza "dr. M. Burgos"; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina
description Autophagy is involved in several physiological and pathological processes. One of the key roles of the autophagic pathway is to participate in the first line of defense against the invasion of pathogens, as part of the innate immune response. Targeting of intracellular bacteria by the autophagic machinery, either in the cytoplasm or within vacuolar compartments, helps to control bacterial proliferation in the host cell, controlling also the spreading of the infection. In this review we will describe the means used by diverse bacterial pathogens to survive intracellularly and how they are recognized by the autophagic molecular machinery, as well as the mechanisms used to avoid autophagic clearance.
publishDate 2013
dc.date.none.fl_str_mv 2013-09-30
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/9830
Mansilla Pareja, MARIA EUGENIA; Colombo, Maria Isabel; Autophagic clearance of bacterial pathogens: molecular recognition of intracellular microorganisms; Frontiers; Frontiers in Cellular and Infection Microbiology; 3; 54; 30-9-2013; 1-14
2235-2988
url http://hdl.handle.net/11336/9830
identifier_str_mv Mansilla Pareja, MARIA EUGENIA; Colombo, Maria Isabel; Autophagic clearance of bacterial pathogens: molecular recognition of intracellular microorganisms; Frontiers; Frontiers in Cellular and Infection Microbiology; 3; 54; 30-9-2013; 1-14
2235-2988
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://dx.doi.org/10.3389/fcimb.2013.00054
info:eu-repo/semantics/altIdentifier/url/http://journal.frontiersin.org/article/10.3389/fcimb.2013.00054
info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786225/
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
Atribución-NoComercial-CompartirIgual 2.5 Argentina (CC BY-NC-SA 2.5 AR)
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv Atribución-NoComercial-CompartirIgual 2.5 Argentina (CC BY-NC-SA 2.5 AR)
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Frontiers
publisher.none.fl_str_mv Frontiers
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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