Seasonal Phytochemical Variation and Antifungal Evaluation of Different Parts of Epidendrum Mosenii

Autores
Rosa, Patrícia Walter; Machado, Marina Da Silva; Niero, Rivaldo; Zacchino, Susana Alicia Stella; Gette, Maria de Los Angeles; Monache, Franco Delle; Cechinel Filho, Valdir
Año de publicación
2008
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Epidendrum mosenii is a Brazilian medicinal plant, traditionally used to treat infections and pains. This study reports on the chemical composition and microbiological properties of different parts and in different seasons of this plant. Results demonstrate that 4,3’,5’-trihydroxy-3-methoxy-dihydrostilbene (1), 4,5-dihydroxy-3,3-dimethoxy-dihydrostilbene (2) and pholidotin (3) were mainly present in the roots in all seasons, and the yield of mass extract increased their recovery in other parts, such as the stem and leaves for compounds (2) and (3), in summer and winter, respectively. The antifungal results indicate that compounds (1) and (2) have interesting activity against Cryptococcus neoformans, Microsporum gypseum, Trychophyton rubrum and Trychophyton mentagrophytes with MIC values between 62.5 and 125 μg/mL. Taken together, these results strongly suggest that the antifungal properties of E. mosenii are related, at least in part, to the presence of dihydrostilbenes 1 and 2, and this is useful for quality control of phytopreparations based on this plant, justifying the popular use of this plant to treat infections.
Fil: Rosa, Patrícia Walter. Universidade do Vale do Itajaí; Brasil
Fil: Machado, Marina Da Silva. Universidade do Vale do Itajaí; Brasil
Fil: Niero, Rivaldo. Universidade do Vale do Itajaí; Brasil
Fil: Zacchino, Susana Alicia Stella. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina
Fil: Gette, Maria de Los Angeles. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina
Fil: Monache, Franco Delle. Universidade do Vale do Itajaí; Brasil
Fil: Cechinel Filho, Valdir. Universidade do Vale do Itajaí; Brasil
Materia
Epidendrum mosenii
antifungal activity
seasonal variation
dihydrostilbenes
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/94541
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/94541
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Seasonal Phytochemical Variation and Antifungal Evaluation of Different Parts of Epidendrum MoseniiRosa, Patrícia WalterMachado, Marina Da SilvaNiero, RivaldoZacchino, Susana Alicia StellaGette, Maria de Los AngelesMonache, Franco DelleCechinel Filho, ValdirEpidendrum moseniiantifungal activityseasonal variationdihydrostilbeneshttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Epidendrum mosenii is a Brazilian medicinal plant, traditionally used to treat infections and pains. This study reports on the chemical composition and microbiological properties of different parts and in different seasons of this plant. Results demonstrate that 4,3’,5’-trihydroxy-3-methoxy-dihydrostilbene (1), 4,5-dihydroxy-3,3-dimethoxy-dihydrostilbene (2) and pholidotin (3) were mainly present in the roots in all seasons, and the yield of mass extract increased their recovery in other parts, such as the stem and leaves for compounds (2) and (3), in summer and winter, respectively. The antifungal results indicate that compounds (1) and (2) have interesting activity against Cryptococcus neoformans, Microsporum gypseum, Trychophyton rubrum and Trychophyton mentagrophytes with MIC values between 62.5 and 125 μg/mL. Taken together, these results strongly suggest that the antifungal properties of E. mosenii are related, at least in part, to the presence of dihydrostilbenes 1 and 2, and this is useful for quality control of phytopreparations based on this plant, justifying the popular use of this plant to treat infections.Fil: Rosa, Patrícia Walter. Universidade do Vale do Itajaí; BrasilFil: Machado, Marina Da Silva. Universidade do Vale do Itajaí; BrasilFil: Niero, Rivaldo. Universidade do Vale do Itajaí; BrasilFil: Zacchino, Susana Alicia Stella. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; ArgentinaFil: Gette, Maria de Los Angeles. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; ArgentinaFil: Monache, Franco Delle. Universidade do Vale do Itajaí; BrasilFil: Cechinel Filho, Valdir. Universidade do Vale do Itajaí; BrasilNatural Products2008-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/94541Rosa, Patrícia Walter; Machado, Marina Da Silva; Niero, Rivaldo; Zacchino, Susana Alicia Stella; Gette, Maria de Los Angeles; et al.; Seasonal Phytochemical Variation and Antifungal Evaluation of Different Parts of Epidendrum Mosenii; Natural Products; Natural Product Communications; 3; 4; 4-2008; 535-5381934-578XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://journals.sagepub.com/doi/abs/10.1177/1934578X0800300412info:eu-repo/semantics/altIdentifier/doi/10.1177%2F1934578X0800300412info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:22:57Zoai:ri.conicet.gov.ar:11336/94541instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:22:57.915CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Seasonal Phytochemical Variation and Antifungal Evaluation of Different Parts of Epidendrum Mosenii
title Seasonal Phytochemical Variation and Antifungal Evaluation of Different Parts of Epidendrum Mosenii
spellingShingle Seasonal Phytochemical Variation and Antifungal Evaluation of Different Parts of Epidendrum Mosenii
Rosa, Patrícia Walter
Epidendrum mosenii
antifungal activity
seasonal variation
dihydrostilbenes
title_short Seasonal Phytochemical Variation and Antifungal Evaluation of Different Parts of Epidendrum Mosenii
title_full Seasonal Phytochemical Variation and Antifungal Evaluation of Different Parts of Epidendrum Mosenii
title_fullStr Seasonal Phytochemical Variation and Antifungal Evaluation of Different Parts of Epidendrum Mosenii
title_full_unstemmed Seasonal Phytochemical Variation and Antifungal Evaluation of Different Parts of Epidendrum Mosenii
title_sort Seasonal Phytochemical Variation and Antifungal Evaluation of Different Parts of Epidendrum Mosenii
dc.creator.none.fl_str_mv Rosa, Patrícia Walter
Machado, Marina Da Silva
Niero, Rivaldo
Zacchino, Susana Alicia Stella
Gette, Maria de Los Angeles
Monache, Franco Delle
Cechinel Filho, Valdir
author Rosa, Patrícia Walter
author_facet Rosa, Patrícia Walter
Machado, Marina Da Silva
Niero, Rivaldo
Zacchino, Susana Alicia Stella
Gette, Maria de Los Angeles
Monache, Franco Delle
Cechinel Filho, Valdir
author_role author
author2 Machado, Marina Da Silva
Niero, Rivaldo
Zacchino, Susana Alicia Stella
Gette, Maria de Los Angeles
Monache, Franco Delle
Cechinel Filho, Valdir
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Epidendrum mosenii
antifungal activity
seasonal variation
dihydrostilbenes
topic Epidendrum mosenii
antifungal activity
seasonal variation
dihydrostilbenes
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Epidendrum mosenii is a Brazilian medicinal plant, traditionally used to treat infections and pains. This study reports on the chemical composition and microbiological properties of different parts and in different seasons of this plant. Results demonstrate that 4,3’,5’-trihydroxy-3-methoxy-dihydrostilbene (1), 4,5-dihydroxy-3,3-dimethoxy-dihydrostilbene (2) and pholidotin (3) were mainly present in the roots in all seasons, and the yield of mass extract increased their recovery in other parts, such as the stem and leaves for compounds (2) and (3), in summer and winter, respectively. The antifungal results indicate that compounds (1) and (2) have interesting activity against Cryptococcus neoformans, Microsporum gypseum, Trychophyton rubrum and Trychophyton mentagrophytes with MIC values between 62.5 and 125 μg/mL. Taken together, these results strongly suggest that the antifungal properties of E. mosenii are related, at least in part, to the presence of dihydrostilbenes 1 and 2, and this is useful for quality control of phytopreparations based on this plant, justifying the popular use of this plant to treat infections.
Fil: Rosa, Patrícia Walter. Universidade do Vale do Itajaí; Brasil
Fil: Machado, Marina Da Silva. Universidade do Vale do Itajaí; Brasil
Fil: Niero, Rivaldo. Universidade do Vale do Itajaí; Brasil
Fil: Zacchino, Susana Alicia Stella. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina
Fil: Gette, Maria de Los Angeles. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina
Fil: Monache, Franco Delle. Universidade do Vale do Itajaí; Brasil
Fil: Cechinel Filho, Valdir. Universidade do Vale do Itajaí; Brasil
description Epidendrum mosenii is a Brazilian medicinal plant, traditionally used to treat infections and pains. This study reports on the chemical composition and microbiological properties of different parts and in different seasons of this plant. Results demonstrate that 4,3’,5’-trihydroxy-3-methoxy-dihydrostilbene (1), 4,5-dihydroxy-3,3-dimethoxy-dihydrostilbene (2) and pholidotin (3) were mainly present in the roots in all seasons, and the yield of mass extract increased their recovery in other parts, such as the stem and leaves for compounds (2) and (3), in summer and winter, respectively. The antifungal results indicate that compounds (1) and (2) have interesting activity against Cryptococcus neoformans, Microsporum gypseum, Trychophyton rubrum and Trychophyton mentagrophytes with MIC values between 62.5 and 125 μg/mL. Taken together, these results strongly suggest that the antifungal properties of E. mosenii are related, at least in part, to the presence of dihydrostilbenes 1 and 2, and this is useful for quality control of phytopreparations based on this plant, justifying the popular use of this plant to treat infections.
publishDate 2008
dc.date.none.fl_str_mv 2008-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/94541
Rosa, Patrícia Walter; Machado, Marina Da Silva; Niero, Rivaldo; Zacchino, Susana Alicia Stella; Gette, Maria de Los Angeles; et al.; Seasonal Phytochemical Variation and Antifungal Evaluation of Different Parts of Epidendrum Mosenii; Natural Products; Natural Product Communications; 3; 4; 4-2008; 535-538
1934-578X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/94541
identifier_str_mv Rosa, Patrícia Walter; Machado, Marina Da Silva; Niero, Rivaldo; Zacchino, Susana Alicia Stella; Gette, Maria de Los Angeles; et al.; Seasonal Phytochemical Variation and Antifungal Evaluation of Different Parts of Epidendrum Mosenii; Natural Products; Natural Product Communications; 3; 4; 4-2008; 535-538
1934-578X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://journals.sagepub.com/doi/abs/10.1177/1934578X0800300412
info:eu-repo/semantics/altIdentifier/doi/10.1177%2F1934578X0800300412
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Natural Products
publisher.none.fl_str_mv Natural Products
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846083376614735872
score 13.22299

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