Production and Characterization of Glass Microspheres for Hepatic Cancer Treatment

Autores
Bortot, M. B.; Prastalo, S.; Prado, Miguel Oscar
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A simple theoretical mathematical model was developed to assess the process of glass particles spheroidization in a propane-butane-oxygen flame. The model has been designed to gain a better understanding of the dependency amongst the variables that come into play during glass spheroidization. Using the model and theoretical values of: glass viscosity, density, shear modulus, thermal conductivity as well as measured values of the temperature of the flame at different positions, particle size and the vitreous transition temperature, the particle«s time-temperature history was calculated inside the flame for different particle sizes and trajectories. For yttrium aluminosilicate (YAS) glass microspheres, of diameter size: 20-50 microns, it was found that the spheroidization process is completed within the flame in short time intervals in the order of 4 x 10-3 to 9 x 10-3 seconds, depending on its thermal trajectory and size of the particle. In this paper the trajectories, degree of spheroidization, temperature variations and velocities of different particle sizes are shown. Using the results obtained from the model, YAS glass microspheres were produced and characterized. Density measurements were done using Helium Pycnometry, chemical composition was studied by Energy Dispersive Spectroscopy. The microsphere surface was characterized using Scanning Electron Microscopy and the glass was thermally characterized by means of Differential Thermal Analysis.
Fil: Bortot, M. B.. Comisión Nacional de Energía Atómica. Gerencia del Area de Energía Nuclear. Instituto Balseiro; Argentina. Universidad Nacional de Cuyo; Argentina
Fil: Prastalo, S.. Comision Nacional de Energia Atomica. Gerencia de Area de Aplicaciones de la Tecnologia Nuclear. Gerencia de Investigacion Aplicada. Grupo de Materiales Nucleares; Argentina
Fil: Prado, Miguel Oscar. Comision Nacional de Energia Atomica. Gerencia de Area de Aplicaciones de la Tecnologia Nuclear. Gerencia de Investigacion Aplicada. Grupo de Materiales Nucleares; Argentina. Comisión Nacional de Energía Atómica. Gerencia del Area de Energía Nuclear. Instituto Balseiro; Argentina. Universidad Nacional de Cuyo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
SPHEROIDIZATION
YTTRIUM ALUMINOSILICATE GLASS
GLASS MICROSPHERES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/11054
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Production and Characterization of Glass Microspheres for Hepatic Cancer TreatmentBortot, M. B.Prastalo, S.Prado, Miguel OscarSPHEROIDIZATIONYTTRIUM ALUMINOSILICATE GLASSGLASS MICROSPHEREShttps://purl.org/becyt/ford/2.5https://purl.org/becyt/ford/2https://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3A simple theoretical mathematical model was developed to assess the process of glass particles spheroidization in a propane-butane-oxygen flame. The model has been designed to gain a better understanding of the dependency amongst the variables that come into play during glass spheroidization. Using the model and theoretical values of: glass viscosity, density, shear modulus, thermal conductivity as well as measured values of the temperature of the flame at different positions, particle size and the vitreous transition temperature, the particle«s time-temperature history was calculated inside the flame for different particle sizes and trajectories. For yttrium aluminosilicate (YAS) glass microspheres, of diameter size: 20-50 microns, it was found that the spheroidization process is completed within the flame in short time intervals in the order of 4 x 10-3 to 9 x 10-3 seconds, depending on its thermal trajectory and size of the particle. In this paper the trajectories, degree of spheroidization, temperature variations and velocities of different particle sizes are shown. Using the results obtained from the model, YAS glass microspheres were produced and characterized. Density measurements were done using Helium Pycnometry, chemical composition was studied by Energy Dispersive Spectroscopy. The microsphere surface was characterized using Scanning Electron Microscopy and the glass was thermally characterized by means of Differential Thermal Analysis.Fil: Bortot, M. B.. Comisión Nacional de Energía Atómica. Gerencia del Area de Energía Nuclear. Instituto Balseiro; Argentina. Universidad Nacional de Cuyo; ArgentinaFil: Prastalo, S.. Comision Nacional de Energia Atomica. Gerencia de Area de Aplicaciones de la Tecnologia Nuclear. Gerencia de Investigacion Aplicada. Grupo de Materiales Nucleares; ArgentinaFil: Prado, Miguel Oscar. Comision Nacional de Energia Atomica. Gerencia de Area de Aplicaciones de la Tecnologia Nuclear. Gerencia de Investigacion Aplicada. Grupo de Materiales Nucleares; Argentina. Comisión Nacional de Energía Atómica. Gerencia del Area de Energía Nuclear. Instituto Balseiro; Argentina. Universidad Nacional de Cuyo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaElsevier Science2012-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/11054Bortot, M. B.; Prastalo, S.; Prado, Miguel Oscar; Production and Characterization of Glass Microspheres for Hepatic Cancer Treatment; Elsevier Science; Procedia Materials Science; 1; 1-2012; 351-3582211-8128enginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S221181281200048Xinfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.mspro.2012.06.047info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:45:39Zoai:ri.conicet.gov.ar:11336/11054instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:45:40.083CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Production and Characterization of Glass Microspheres for Hepatic Cancer Treatment
title Production and Characterization of Glass Microspheres for Hepatic Cancer Treatment
spellingShingle Production and Characterization of Glass Microspheres for Hepatic Cancer Treatment
Bortot, M. B.
SPHEROIDIZATION
YTTRIUM ALUMINOSILICATE GLASS
GLASS MICROSPHERES
title_short Production and Characterization of Glass Microspheres for Hepatic Cancer Treatment
title_full Production and Characterization of Glass Microspheres for Hepatic Cancer Treatment
title_fullStr Production and Characterization of Glass Microspheres for Hepatic Cancer Treatment
title_full_unstemmed Production and Characterization of Glass Microspheres for Hepatic Cancer Treatment
title_sort Production and Characterization of Glass Microspheres for Hepatic Cancer Treatment
dc.creator.none.fl_str_mv Bortot, M. B.
Prastalo, S.
Prado, Miguel Oscar
author Bortot, M. B.
author_facet Bortot, M. B.
Prastalo, S.
Prado, Miguel Oscar
author_role author
author2 Prastalo, S.
Prado, Miguel Oscar
author2_role author
author
dc.subject.none.fl_str_mv SPHEROIDIZATION
YTTRIUM ALUMINOSILICATE GLASS
GLASS MICROSPHERES
topic SPHEROIDIZATION
YTTRIUM ALUMINOSILICATE GLASS
GLASS MICROSPHERES
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.5
https://purl.org/becyt/ford/2
https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv A simple theoretical mathematical model was developed to assess the process of glass particles spheroidization in a propane-butane-oxygen flame. The model has been designed to gain a better understanding of the dependency amongst the variables that come into play during glass spheroidization. Using the model and theoretical values of: glass viscosity, density, shear modulus, thermal conductivity as well as measured values of the temperature of the flame at different positions, particle size and the vitreous transition temperature, the particle«s time-temperature history was calculated inside the flame for different particle sizes and trajectories. For yttrium aluminosilicate (YAS) glass microspheres, of diameter size: 20-50 microns, it was found that the spheroidization process is completed within the flame in short time intervals in the order of 4 x 10-3 to 9 x 10-3 seconds, depending on its thermal trajectory and size of the particle. In this paper the trajectories, degree of spheroidization, temperature variations and velocities of different particle sizes are shown. Using the results obtained from the model, YAS glass microspheres were produced and characterized. Density measurements were done using Helium Pycnometry, chemical composition was studied by Energy Dispersive Spectroscopy. The microsphere surface was characterized using Scanning Electron Microscopy and the glass was thermally characterized by means of Differential Thermal Analysis.
Fil: Bortot, M. B.. Comisión Nacional de Energía Atómica. Gerencia del Area de Energía Nuclear. Instituto Balseiro; Argentina. Universidad Nacional de Cuyo; Argentina
Fil: Prastalo, S.. Comision Nacional de Energia Atomica. Gerencia de Area de Aplicaciones de la Tecnologia Nuclear. Gerencia de Investigacion Aplicada. Grupo de Materiales Nucleares; Argentina
Fil: Prado, Miguel Oscar. Comision Nacional de Energia Atomica. Gerencia de Area de Aplicaciones de la Tecnologia Nuclear. Gerencia de Investigacion Aplicada. Grupo de Materiales Nucleares; Argentina. Comisión Nacional de Energía Atómica. Gerencia del Area de Energía Nuclear. Instituto Balseiro; Argentina. Universidad Nacional de Cuyo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description A simple theoretical mathematical model was developed to assess the process of glass particles spheroidization in a propane-butane-oxygen flame. The model has been designed to gain a better understanding of the dependency amongst the variables that come into play during glass spheroidization. Using the model and theoretical values of: glass viscosity, density, shear modulus, thermal conductivity as well as measured values of the temperature of the flame at different positions, particle size and the vitreous transition temperature, the particle«s time-temperature history was calculated inside the flame for different particle sizes and trajectories. For yttrium aluminosilicate (YAS) glass microspheres, of diameter size: 20-50 microns, it was found that the spheroidization process is completed within the flame in short time intervals in the order of 4 x 10-3 to 9 x 10-3 seconds, depending on its thermal trajectory and size of the particle. In this paper the trajectories, degree of spheroidization, temperature variations and velocities of different particle sizes are shown. Using the results obtained from the model, YAS glass microspheres were produced and characterized. Density measurements were done using Helium Pycnometry, chemical composition was studied by Energy Dispersive Spectroscopy. The microsphere surface was characterized using Scanning Electron Microscopy and the glass was thermally characterized by means of Differential Thermal Analysis.
publishDate 2012
dc.date.none.fl_str_mv 2012-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/11054
Bortot, M. B.; Prastalo, S.; Prado, Miguel Oscar; Production and Characterization of Glass Microspheres for Hepatic Cancer Treatment; Elsevier Science; Procedia Materials Science; 1; 1-2012; 351-358
2211-8128
url http://hdl.handle.net/11336/11054
identifier_str_mv Bortot, M. B.; Prastalo, S.; Prado, Miguel Oscar; Production and Characterization of Glass Microspheres for Hepatic Cancer Treatment; Elsevier Science; Procedia Materials Science; 1; 1-2012; 351-358
2211-8128
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S221181281200048X
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.mspro.2012.06.047
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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