Antimicrobial properties of prunin, a citric flavanone glucoside, and its prunin 6″-O-lauroyl ester

Autores
Celiz, Gustavo; Audisio, Marcela Carina; Daz, Mirta Elizabeth
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Aims: To determine the antimicrobial potential of prunin (P), a flavanone glucoside resulting from the hydrolysis of naringin present in grapefruit, and of its prunin 6″-O-lauroyl ester (PL), synthesized by enzymatic catalysis. Methods and Results: P and its lauroyl ester were tested against Gram-negative and Gram-positive bacteria, yeasts and moulds. P showed no inhibitory effect against the micro-organisms assayed, but stimulated growth of Pseudomonas aeruginosa and different Bacilllus sp. However, 150 g ml-1 of PL inhibited Escherichia coli, Salmonella enterica serovar Enteritidis, Salmonella enterica serovar Typhimurium, many Bacillus sp., Staphylococcus aureus ATCC29213, Enterococcus avium DSMZ17511, and different Listeria monocytogenes strains. In the last case, L. monocytogenes, sensitive or bacteriocin-resistant cells, lost nearly 4-log reductions after 30 min of contact. A bactericidal mode of action was determined using both scanning and transmission electronic microscopies. Conclusions: PL could be used as a food additive, because at low concentration (150 g ml-1) it exhibited antimicrobial activity against important food-borne pathogens. A bactericidal effect was also determined on L. monocytogenes sensitive and bacteriocin-resistant mutant strains. P did not show any antimicrobial property at all. Significance and Impact of the Study: PL is a potential antimicrobial compound with a high anti-Listeria property. © 2010 The Society for Applied Microbiology.
Fil: Celiz, Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Investigaciones para la Industria Química. Universidad Nacional de Salta. Facultad de Ingeniería. Instituto de Investigaciones para la Industria Química; Argentina
Fil: Audisio, Marcela Carina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Investigaciones para la Industria Química. Universidad Nacional de Salta. Facultad de Ingeniería. Instituto de Investigaciones para la Industria Química; Argentina
Fil: Daz, Mirta Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Investigaciones para la Industria Química. Universidad Nacional de Salta. Facultad de Ingeniería. Instituto de Investigaciones para la Industria Química; Argentina
Materia
ANTIMICROBIAL SUBSTANCES
GRAPEFRUITS
LISTERIA MONOCYTOGENES
PRUNIN
PRUNIN 6″-O-LAUROYL ESTER
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/61710
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/61710
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Antimicrobial properties of prunin, a citric flavanone glucoside, and its prunin 6″-O-lauroyl esterCeliz, GustavoAudisio, Marcela CarinaDaz, Mirta ElizabethANTIMICROBIAL SUBSTANCESGRAPEFRUITSLISTERIA MONOCYTOGENESPRUNINPRUNIN 6″-O-LAUROYL ESTERhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Aims: To determine the antimicrobial potential of prunin (P), a flavanone glucoside resulting from the hydrolysis of naringin present in grapefruit, and of its prunin 6″-O-lauroyl ester (PL), synthesized by enzymatic catalysis. Methods and Results: P and its lauroyl ester were tested against Gram-negative and Gram-positive bacteria, yeasts and moulds. P showed no inhibitory effect against the micro-organisms assayed, but stimulated growth of Pseudomonas aeruginosa and different Bacilllus sp. However, 150 g ml-1 of PL inhibited Escherichia coli, Salmonella enterica serovar Enteritidis, Salmonella enterica serovar Typhimurium, many Bacillus sp., Staphylococcus aureus ATCC29213, Enterococcus avium DSMZ17511, and different Listeria monocytogenes strains. In the last case, L. monocytogenes, sensitive or bacteriocin-resistant cells, lost nearly 4-log reductions after 30 min of contact. A bactericidal mode of action was determined using both scanning and transmission electronic microscopies. Conclusions: PL could be used as a food additive, because at low concentration (150 g ml-1) it exhibited antimicrobial activity against important food-borne pathogens. A bactericidal effect was also determined on L. monocytogenes sensitive and bacteriocin-resistant mutant strains. P did not show any antimicrobial property at all. Significance and Impact of the Study: PL is a potential antimicrobial compound with a high anti-Listeria property. © 2010 The Society for Applied Microbiology.Fil: Celiz, Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Investigaciones para la Industria Química. Universidad Nacional de Salta. Facultad de Ingeniería. Instituto de Investigaciones para la Industria Química; ArgentinaFil: Audisio, Marcela Carina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Investigaciones para la Industria Química. Universidad Nacional de Salta. Facultad de Ingeniería. Instituto de Investigaciones para la Industria Química; ArgentinaFil: Daz, Mirta Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Investigaciones para la Industria Química. Universidad Nacional de Salta. Facultad de Ingeniería. Instituto de Investigaciones para la Industria Química; ArgentinaWiley Blackwell Publishing, Inc2010-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/61710Celiz, Gustavo; Audisio, Marcela Carina; Daz, Mirta Elizabeth; Antimicrobial properties of prunin, a citric flavanone glucoside, and its prunin 6″-O-lauroyl ester; Wiley Blackwell Publishing, Inc; Journal of Applied Microbiology; 109; 4; 10-2010; 1450-14571364-5072CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1111/j.1365-2672.2010.04773.xinfo:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2672.2010.04773.xinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T12:01:15Zoai:ri.conicet.gov.ar:11336/61710instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 12:01:16.149CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Antimicrobial properties of prunin, a citric flavanone glucoside, and its prunin 6″-O-lauroyl ester
title Antimicrobial properties of prunin, a citric flavanone glucoside, and its prunin 6″-O-lauroyl ester
spellingShingle Antimicrobial properties of prunin, a citric flavanone glucoside, and its prunin 6″-O-lauroyl ester
Celiz, Gustavo
ANTIMICROBIAL SUBSTANCES
GRAPEFRUITS
LISTERIA MONOCYTOGENES
PRUNIN
PRUNIN 6″-O-LAUROYL ESTER
title_short Antimicrobial properties of prunin, a citric flavanone glucoside, and its prunin 6″-O-lauroyl ester
title_full Antimicrobial properties of prunin, a citric flavanone glucoside, and its prunin 6″-O-lauroyl ester
title_fullStr Antimicrobial properties of prunin, a citric flavanone glucoside, and its prunin 6″-O-lauroyl ester
title_full_unstemmed Antimicrobial properties of prunin, a citric flavanone glucoside, and its prunin 6″-O-lauroyl ester
title_sort Antimicrobial properties of prunin, a citric flavanone glucoside, and its prunin 6″-O-lauroyl ester
dc.creator.none.fl_str_mv Celiz, Gustavo
Audisio, Marcela Carina
Daz, Mirta Elizabeth
author Celiz, Gustavo
author_facet Celiz, Gustavo
Audisio, Marcela Carina
Daz, Mirta Elizabeth
author_role author
author2 Audisio, Marcela Carina
Daz, Mirta Elizabeth
author2_role author
author
dc.subject.none.fl_str_mv ANTIMICROBIAL SUBSTANCES
GRAPEFRUITS
LISTERIA MONOCYTOGENES
PRUNIN
PRUNIN 6″-O-LAUROYL ESTER
topic ANTIMICROBIAL SUBSTANCES
GRAPEFRUITS
LISTERIA MONOCYTOGENES
PRUNIN
PRUNIN 6″-O-LAUROYL ESTER
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Aims: To determine the antimicrobial potential of prunin (P), a flavanone glucoside resulting from the hydrolysis of naringin present in grapefruit, and of its prunin 6″-O-lauroyl ester (PL), synthesized by enzymatic catalysis. Methods and Results: P and its lauroyl ester were tested against Gram-negative and Gram-positive bacteria, yeasts and moulds. P showed no inhibitory effect against the micro-organisms assayed, but stimulated growth of Pseudomonas aeruginosa and different Bacilllus sp. However, 150 g ml-1 of PL inhibited Escherichia coli, Salmonella enterica serovar Enteritidis, Salmonella enterica serovar Typhimurium, many Bacillus sp., Staphylococcus aureus ATCC29213, Enterococcus avium DSMZ17511, and different Listeria monocytogenes strains. In the last case, L. monocytogenes, sensitive or bacteriocin-resistant cells, lost nearly 4-log reductions after 30 min of contact. A bactericidal mode of action was determined using both scanning and transmission electronic microscopies. Conclusions: PL could be used as a food additive, because at low concentration (150 g ml-1) it exhibited antimicrobial activity against important food-borne pathogens. A bactericidal effect was also determined on L. monocytogenes sensitive and bacteriocin-resistant mutant strains. P did not show any antimicrobial property at all. Significance and Impact of the Study: PL is a potential antimicrobial compound with a high anti-Listeria property. © 2010 The Society for Applied Microbiology.
Fil: Celiz, Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Investigaciones para la Industria Química. Universidad Nacional de Salta. Facultad de Ingeniería. Instituto de Investigaciones para la Industria Química; Argentina
Fil: Audisio, Marcela Carina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Investigaciones para la Industria Química. Universidad Nacional de Salta. Facultad de Ingeniería. Instituto de Investigaciones para la Industria Química; Argentina
Fil: Daz, Mirta Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Investigaciones para la Industria Química. Universidad Nacional de Salta. Facultad de Ingeniería. Instituto de Investigaciones para la Industria Química; Argentina
description Aims: To determine the antimicrobial potential of prunin (P), a flavanone glucoside resulting from the hydrolysis of naringin present in grapefruit, and of its prunin 6″-O-lauroyl ester (PL), synthesized by enzymatic catalysis. Methods and Results: P and its lauroyl ester were tested against Gram-negative and Gram-positive bacteria, yeasts and moulds. P showed no inhibitory effect against the micro-organisms assayed, but stimulated growth of Pseudomonas aeruginosa and different Bacilllus sp. However, 150 g ml-1 of PL inhibited Escherichia coli, Salmonella enterica serovar Enteritidis, Salmonella enterica serovar Typhimurium, many Bacillus sp., Staphylococcus aureus ATCC29213, Enterococcus avium DSMZ17511, and different Listeria monocytogenes strains. In the last case, L. monocytogenes, sensitive or bacteriocin-resistant cells, lost nearly 4-log reductions after 30 min of contact. A bactericidal mode of action was determined using both scanning and transmission electronic microscopies. Conclusions: PL could be used as a food additive, because at low concentration (150 g ml-1) it exhibited antimicrobial activity against important food-borne pathogens. A bactericidal effect was also determined on L. monocytogenes sensitive and bacteriocin-resistant mutant strains. P did not show any antimicrobial property at all. Significance and Impact of the Study: PL is a potential antimicrobial compound with a high anti-Listeria property. © 2010 The Society for Applied Microbiology.
publishDate 2010
dc.date.none.fl_str_mv 2010-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/61710
Celiz, Gustavo; Audisio, Marcela Carina; Daz, Mirta Elizabeth; Antimicrobial properties of prunin, a citric flavanone glucoside, and its prunin 6″-O-lauroyl ester; Wiley Blackwell Publishing, Inc; Journal of Applied Microbiology; 109; 4; 10-2010; 1450-1457
1364-5072
CONICET Digital
CONICET
url http://hdl.handle.net/11336/61710
identifier_str_mv Celiz, Gustavo; Audisio, Marcela Carina; Daz, Mirta Elizabeth; Antimicrobial properties of prunin, a citric flavanone glucoside, and its prunin 6″-O-lauroyl ester; Wiley Blackwell Publishing, Inc; Journal of Applied Microbiology; 109; 4; 10-2010; 1450-1457
1364-5072
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1111/j.1365-2672.2010.04773.x
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2672.2010.04773.x
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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