Impact of the Three-Dimensional Arrangements of Polyhydroxylated Crosslinkers on the Resulting Properties of Chitosan-Based Hydrogels

Autores
Díaz Bukvic, Gema; Ojeda Henriquez, Martin; Rodríguez Vannini, Agustín Brandon; Fidalgo, María Marta; Salvay, Andrés Gerardo; Rossi, Ezequiel; Errea, María Inés
Año de publicación
2024
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Chitosan was subjected to a crosslinking reaction with three polyhydroxylated diacids (glucaric (GlcA), mannaric (ManA), and mucic (MucA) acids) that only differ in the spatial orientation of their hydroxyl groups. This work aimed to obtain experimental evidence of the impact of the three-dimensional arrangement of the crosslinkers on the resulting properties of the products. In all the cases, the products were hydrogels, and their chemical structures were fully elucidated by FT-IR spectroscopy and conductometric titration. Thermogravimetric and morphological studies were also carried out. The specific surface area of all the products was similar and higher than that of native chitosan. Moreover, all hydrogels were characterized in terms of viscoelastic properties and long-term stability under external perturbation. Furthermore, their lead adsorption efficiency and swelling capacity were assessed. Despite the resemblant chemical structure in all the hydrogels, Ch/ManA exhibited the highest lead adsorption capacity, (Ch/ManA: 93.8 mg g−1, Ch/GlcA: 82.9 mg g−1, Ch/MucA: 79.2 mg g−1), while Ch/GlcA exhibited a remarkably higher swelling capacity (i.e., ~30% more than Ch/MucA and ~40% more than Ch/ManA). The results obtained herein evidenced that the selection of the polyhydroxylated crosslinker with the appropriate three-dimensional structure could be crucial to finely adjust the final materials’ features.
Fil: Díaz Bukvic, Gema. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Tecnológico de Buenos Aires; Argentina
Fil: Ojeda Henriquez, Martin. Instituto Tecnológico de Buenos Aires; Argentina
Fil: Rodríguez Vannini, Agustín Brandon. Instituto Tecnológico de Buenos Aires; Argentina
Fil: Fidalgo, María Marta. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. University of Missouri; Estados Unidos
Fil: Salvay, Andrés Gerardo. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina
Fil: Rossi, Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Tecnológico de Buenos Aires; Argentina
Fil: Errea, María Inés. Instituto Tecnológico de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
crosslinked chitosan
polyhydroxylated crosslinkers
three-dimensional arrangement
hydrogels
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/242670
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/242670
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Impact of the Three-Dimensional Arrangements of Polyhydroxylated Crosslinkers on the Resulting Properties of Chitosan-Based HydrogelsDíaz Bukvic, GemaOjeda Henriquez, MartinRodríguez Vannini, Agustín BrandonFidalgo, María MartaSalvay, Andrés GerardoRossi, EzequielErrea, María Inéscrosslinked chitosanpolyhydroxylated crosslinkersthree-dimensional arrangementhydrogelshttps://purl.org/becyt/ford/2.4https://purl.org/becyt/ford/2Chitosan was subjected to a crosslinking reaction with three polyhydroxylated diacids (glucaric (GlcA), mannaric (ManA), and mucic (MucA) acids) that only differ in the spatial orientation of their hydroxyl groups. This work aimed to obtain experimental evidence of the impact of the three-dimensional arrangement of the crosslinkers on the resulting properties of the products. In all the cases, the products were hydrogels, and their chemical structures were fully elucidated by FT-IR spectroscopy and conductometric titration. Thermogravimetric and morphological studies were also carried out. The specific surface area of all the products was similar and higher than that of native chitosan. Moreover, all hydrogels were characterized in terms of viscoelastic properties and long-term stability under external perturbation. Furthermore, their lead adsorption efficiency and swelling capacity were assessed. Despite the resemblant chemical structure in all the hydrogels, Ch/ManA exhibited the highest lead adsorption capacity, (Ch/ManA: 93.8 mg g−1, Ch/GlcA: 82.9 mg g−1, Ch/MucA: 79.2 mg g−1), while Ch/GlcA exhibited a remarkably higher swelling capacity (i.e., ~30% more than Ch/MucA and ~40% more than Ch/ManA). The results obtained herein evidenced that the selection of the polyhydroxylated crosslinker with the appropriate three-dimensional structure could be crucial to finely adjust the final materials’ features.Fil: Díaz Bukvic, Gema. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Tecnológico de Buenos Aires; ArgentinaFil: Ojeda Henriquez, Martin. Instituto Tecnológico de Buenos Aires; ArgentinaFil: Rodríguez Vannini, Agustín Brandon. Instituto Tecnológico de Buenos Aires; ArgentinaFil: Fidalgo, María Marta. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. University of Missouri; Estados UnidosFil: Salvay, Andrés Gerardo. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; ArgentinaFil: Rossi, Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Tecnológico de Buenos Aires; ArgentinaFil: Errea, María Inés. Instituto Tecnológico de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaMDPI2024-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/242670Díaz Bukvic, Gema; Ojeda Henriquez, Martin; Rodríguez Vannini, Agustín Brandon; Fidalgo, María Marta; Salvay, Andrés Gerardo; et al.; Impact of the Three-Dimensional Arrangements of Polyhydroxylated Crosslinkers on the Resulting Properties of Chitosan-Based Hydrogels; MDPI; Polysaccharides; 5; 3; 8-2024; 358-3792673-4176CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2673-4176/5/3/23info:eu-repo/semantics/altIdentifier/doi/10.3390/polysaccharides5030023info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:34:16Zoai:ri.conicet.gov.ar:11336/242670instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:34:16.878CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Impact of the Three-Dimensional Arrangements of Polyhydroxylated Crosslinkers on the Resulting Properties of Chitosan-Based Hydrogels
title Impact of the Three-Dimensional Arrangements of Polyhydroxylated Crosslinkers on the Resulting Properties of Chitosan-Based Hydrogels
spellingShingle Impact of the Three-Dimensional Arrangements of Polyhydroxylated Crosslinkers on the Resulting Properties of Chitosan-Based Hydrogels
Díaz Bukvic, Gema
crosslinked chitosan
polyhydroxylated crosslinkers
three-dimensional arrangement
hydrogels
title_short Impact of the Three-Dimensional Arrangements of Polyhydroxylated Crosslinkers on the Resulting Properties of Chitosan-Based Hydrogels
title_full Impact of the Three-Dimensional Arrangements of Polyhydroxylated Crosslinkers on the Resulting Properties of Chitosan-Based Hydrogels
title_fullStr Impact of the Three-Dimensional Arrangements of Polyhydroxylated Crosslinkers on the Resulting Properties of Chitosan-Based Hydrogels
title_full_unstemmed Impact of the Three-Dimensional Arrangements of Polyhydroxylated Crosslinkers on the Resulting Properties of Chitosan-Based Hydrogels
title_sort Impact of the Three-Dimensional Arrangements of Polyhydroxylated Crosslinkers on the Resulting Properties of Chitosan-Based Hydrogels
dc.creator.none.fl_str_mv Díaz Bukvic, Gema
Ojeda Henriquez, Martin
Rodríguez Vannini, Agustín Brandon
Fidalgo, María Marta
Salvay, Andrés Gerardo
Rossi, Ezequiel
Errea, María Inés
author Díaz Bukvic, Gema
author_facet Díaz Bukvic, Gema
Ojeda Henriquez, Martin
Rodríguez Vannini, Agustín Brandon
Fidalgo, María Marta
Salvay, Andrés Gerardo
Rossi, Ezequiel
Errea, María Inés
author_role author
author2 Ojeda Henriquez, Martin
Rodríguez Vannini, Agustín Brandon
Fidalgo, María Marta
Salvay, Andrés Gerardo
Rossi, Ezequiel
Errea, María Inés
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv crosslinked chitosan
polyhydroxylated crosslinkers
three-dimensional arrangement
hydrogels
topic crosslinked chitosan
polyhydroxylated crosslinkers
three-dimensional arrangement
hydrogels
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.4
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Chitosan was subjected to a crosslinking reaction with three polyhydroxylated diacids (glucaric (GlcA), mannaric (ManA), and mucic (MucA) acids) that only differ in the spatial orientation of their hydroxyl groups. This work aimed to obtain experimental evidence of the impact of the three-dimensional arrangement of the crosslinkers on the resulting properties of the products. In all the cases, the products were hydrogels, and their chemical structures were fully elucidated by FT-IR spectroscopy and conductometric titration. Thermogravimetric and morphological studies were also carried out. The specific surface area of all the products was similar and higher than that of native chitosan. Moreover, all hydrogels were characterized in terms of viscoelastic properties and long-term stability under external perturbation. Furthermore, their lead adsorption efficiency and swelling capacity were assessed. Despite the resemblant chemical structure in all the hydrogels, Ch/ManA exhibited the highest lead adsorption capacity, (Ch/ManA: 93.8 mg g−1, Ch/GlcA: 82.9 mg g−1, Ch/MucA: 79.2 mg g−1), while Ch/GlcA exhibited a remarkably higher swelling capacity (i.e., ~30% more than Ch/MucA and ~40% more than Ch/ManA). The results obtained herein evidenced that the selection of the polyhydroxylated crosslinker with the appropriate three-dimensional structure could be crucial to finely adjust the final materials’ features.
Fil: Díaz Bukvic, Gema. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Tecnológico de Buenos Aires; Argentina
Fil: Ojeda Henriquez, Martin. Instituto Tecnológico de Buenos Aires; Argentina
Fil: Rodríguez Vannini, Agustín Brandon. Instituto Tecnológico de Buenos Aires; Argentina
Fil: Fidalgo, María Marta. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. University of Missouri; Estados Unidos
Fil: Salvay, Andrés Gerardo. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina
Fil: Rossi, Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Tecnológico de Buenos Aires; Argentina
Fil: Errea, María Inés. Instituto Tecnológico de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description Chitosan was subjected to a crosslinking reaction with three polyhydroxylated diacids (glucaric (GlcA), mannaric (ManA), and mucic (MucA) acids) that only differ in the spatial orientation of their hydroxyl groups. This work aimed to obtain experimental evidence of the impact of the three-dimensional arrangement of the crosslinkers on the resulting properties of the products. In all the cases, the products were hydrogels, and their chemical structures were fully elucidated by FT-IR spectroscopy and conductometric titration. Thermogravimetric and morphological studies were also carried out. The specific surface area of all the products was similar and higher than that of native chitosan. Moreover, all hydrogels were characterized in terms of viscoelastic properties and long-term stability under external perturbation. Furthermore, their lead adsorption efficiency and swelling capacity were assessed. Despite the resemblant chemical structure in all the hydrogels, Ch/ManA exhibited the highest lead adsorption capacity, (Ch/ManA: 93.8 mg g−1, Ch/GlcA: 82.9 mg g−1, Ch/MucA: 79.2 mg g−1), while Ch/GlcA exhibited a remarkably higher swelling capacity (i.e., ~30% more than Ch/MucA and ~40% more than Ch/ManA). The results obtained herein evidenced that the selection of the polyhydroxylated crosslinker with the appropriate three-dimensional structure could be crucial to finely adjust the final materials’ features.
publishDate 2024
dc.date.none.fl_str_mv 2024-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/242670
Díaz Bukvic, Gema; Ojeda Henriquez, Martin; Rodríguez Vannini, Agustín Brandon; Fidalgo, María Marta; Salvay, Andrés Gerardo; et al.; Impact of the Three-Dimensional Arrangements of Polyhydroxylated Crosslinkers on the Resulting Properties of Chitosan-Based Hydrogels; MDPI; Polysaccharides; 5; 3; 8-2024; 358-379
2673-4176
CONICET Digital
CONICET
url http://hdl.handle.net/11336/242670
identifier_str_mv Díaz Bukvic, Gema; Ojeda Henriquez, Martin; Rodríguez Vannini, Agustín Brandon; Fidalgo, María Marta; Salvay, Andrés Gerardo; et al.; Impact of the Three-Dimensional Arrangements of Polyhydroxylated Crosslinkers on the Resulting Properties of Chitosan-Based Hydrogels; MDPI; Polysaccharides; 5; 3; 8-2024; 358-379
2673-4176
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2673-4176/5/3/23
info:eu-repo/semantics/altIdentifier/doi/10.3390/polysaccharides5030023
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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