Occurrence and bioaccumulation of pharmaceuticals in a fish species inhabiting the Suquía River basin (Córdoba, Argentina)

Autores
Valdés, María Eugenia; Amé, María Valeria; Bistoni, María de los Angeles; Wunderlin, Daniel Alberto
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In SouthAmerica, there is a lack of data concerning the occurrence and levels of pharmaceuticals inmain rivers as well as their negative effects on the biota. Here we report the occurrence as well as the spatial and temporal variations of some common prescribed pharmaceuticals in the Suquía River basin (Córdoba, Argentina). We also report the bioconcentration of two of them in Gambusia affinis, a widely distributed fish species inhabiting the river basin. The influence of the wastewater treatment plant of Córdoba Citywas critical (up to 70 km downstream). Among 15 compounds analyzed, atenolol, carbamazepine and diclofenac were the most frequently detected (reaching sub μg L−1 levels), showing different distribution patterns. Bioconcentration of atenolol and carbamazepine was studied under laboratory controlled conditions. Estimated bioconcentration factors (BCFs) were: 0.13 and 0.08 L kg−1 upon exposure to 100 and 1000 μg L−1 atenolol in water, respectively; while BCFs were 0.7 and 0.9 L kg−1 when exposed to 10 and 100 μg L−1 carbamazepine, respectively. To the extent of our knowledge, this is the first report on pharmaceuticals in superficial waters of Argentina as well as the first
report on the bioaccumulation of atenolol in whole body fish.
Fil: Valdés, María Eugenia. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Diversidad y Ecologia Animal; Argentina
Fil: Amé, María Valeria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina
Fil: Bistoni, María de los Angeles. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Diversidad y Ecologia Animal; Argentina
Fil: Wunderlin, Daniel Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Ciencia y Tecnología de Alimentos Córdoba; Argentina
Materia
Pharmaceuticals
South America
Gambusia Affinis
Carbamazepine
Atenolol
Bioconcentration
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/8011
Acceder
id CONICETDig_20380a82c6dd592df8897978f0baf538
oai_identifier_str oai:ri.conicet.gov.ar:11336/8011
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Occurrence and bioaccumulation of pharmaceuticals in a fish species inhabiting the Suquía River basin (Córdoba, Argentina)Valdés, María EugeniaAmé, María ValeriaBistoni, María de los AngelesWunderlin, Daniel AlbertoPharmaceuticalsSouth AmericaGambusia AffinisCarbamazepineAtenololBioconcentrationhttps://purl.org/becyt/ford/1.5https://purl.org/becyt/ford/1In SouthAmerica, there is a lack of data concerning the occurrence and levels of pharmaceuticals inmain rivers as well as their negative effects on the biota. Here we report the occurrence as well as the spatial and temporal variations of some common prescribed pharmaceuticals in the Suquía River basin (Córdoba, Argentina). We also report the bioconcentration of two of them in Gambusia affinis, a widely distributed fish species inhabiting the river basin. The influence of the wastewater treatment plant of Córdoba Citywas critical (up to 70 km downstream). Among 15 compounds analyzed, atenolol, carbamazepine and diclofenac were the most frequently detected (reaching sub μg L−1 levels), showing different distribution patterns. Bioconcentration of atenolol and carbamazepine was studied under laboratory controlled conditions. Estimated bioconcentration factors (BCFs) were: 0.13 and 0.08 L kg−1 upon exposure to 100 and 1000 μg L−1 atenolol in water, respectively; while BCFs were 0.7 and 0.9 L kg−1 when exposed to 10 and 100 μg L−1 carbamazepine, respectively. To the extent of our knowledge, this is the first report on pharmaceuticals in superficial waters of Argentina as well as the first<br />report on the bioaccumulation of atenolol in whole body fish.Fil: Valdés, María Eugenia. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Diversidad y Ecologia Animal; ArgentinaFil: Amé, María Valeria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Bistoni, María de los Angeles. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Diversidad y Ecologia Animal; ArgentinaFil: Wunderlin, Daniel Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Ciencia y Tecnología de Alimentos Córdoba; ArgentinaElsevier Science2014-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/8011Valdés, María Eugenia; Amé, María Valeria; Bistoni, María de los Angeles; Wunderlin, Daniel Alberto; Occurrence and bioaccumulation of pharmaceuticals in a fish species inhabiting the Suquía River basin (Córdoba, Argentina); Elsevier Science; Science Of The Total Environment; 472; 2-2014; 389-3960048-9697enginfo:eu-repo/semantics/altIdentifier/url/http://dx.doi.org/10.1016/j.scitotenv.2013.10.124info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0048969713013004info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:55:13Zoai:ri.conicet.gov.ar:11336/8011instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:55:13.485CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Occurrence and bioaccumulation of pharmaceuticals in a fish species inhabiting the Suquía River basin (Córdoba, Argentina)
title Occurrence and bioaccumulation of pharmaceuticals in a fish species inhabiting the Suquía River basin (Córdoba, Argentina)
spellingShingle Occurrence and bioaccumulation of pharmaceuticals in a fish species inhabiting the Suquía River basin (Córdoba, Argentina)
Valdés, María Eugenia
Pharmaceuticals
South America
Gambusia Affinis
Carbamazepine
Atenolol
Bioconcentration
title_short Occurrence and bioaccumulation of pharmaceuticals in a fish species inhabiting the Suquía River basin (Córdoba, Argentina)
title_full Occurrence and bioaccumulation of pharmaceuticals in a fish species inhabiting the Suquía River basin (Córdoba, Argentina)
title_fullStr Occurrence and bioaccumulation of pharmaceuticals in a fish species inhabiting the Suquía River basin (Córdoba, Argentina)
title_full_unstemmed Occurrence and bioaccumulation of pharmaceuticals in a fish species inhabiting the Suquía River basin (Córdoba, Argentina)
title_sort Occurrence and bioaccumulation of pharmaceuticals in a fish species inhabiting the Suquía River basin (Córdoba, Argentina)
dc.creator.none.fl_str_mv Valdés, María Eugenia
Amé, María Valeria
Bistoni, María de los Angeles
Wunderlin, Daniel Alberto
author Valdés, María Eugenia
author_facet Valdés, María Eugenia
Amé, María Valeria
Bistoni, María de los Angeles
Wunderlin, Daniel Alberto
author_role author
author2 Amé, María Valeria
Bistoni, María de los Angeles
Wunderlin, Daniel Alberto
author2_role author
author
author
dc.subject.none.fl_str_mv Pharmaceuticals
South America
Gambusia Affinis
Carbamazepine
Atenolol
Bioconcentration
topic Pharmaceuticals
South America
Gambusia Affinis
Carbamazepine
Atenolol
Bioconcentration
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.5
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv In SouthAmerica, there is a lack of data concerning the occurrence and levels of pharmaceuticals inmain rivers as well as their negative effects on the biota. Here we report the occurrence as well as the spatial and temporal variations of some common prescribed pharmaceuticals in the Suquía River basin (Córdoba, Argentina). We also report the bioconcentration of two of them in Gambusia affinis, a widely distributed fish species inhabiting the river basin. The influence of the wastewater treatment plant of Córdoba Citywas critical (up to 70 km downstream). Among 15 compounds analyzed, atenolol, carbamazepine and diclofenac were the most frequently detected (reaching sub μg L−1 levels), showing different distribution patterns. Bioconcentration of atenolol and carbamazepine was studied under laboratory controlled conditions. Estimated bioconcentration factors (BCFs) were: 0.13 and 0.08 L kg−1 upon exposure to 100 and 1000 μg L−1 atenolol in water, respectively; while BCFs were 0.7 and 0.9 L kg−1 when exposed to 10 and 100 μg L−1 carbamazepine, respectively. To the extent of our knowledge, this is the first report on pharmaceuticals in superficial waters of Argentina as well as the first<br />report on the bioaccumulation of atenolol in whole body fish.
Fil: Valdés, María Eugenia. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Diversidad y Ecologia Animal; Argentina
Fil: Amé, María Valeria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina
Fil: Bistoni, María de los Angeles. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Diversidad y Ecologia Animal; Argentina
Fil: Wunderlin, Daniel Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Ciencia y Tecnología de Alimentos Córdoba; Argentina
description In SouthAmerica, there is a lack of data concerning the occurrence and levels of pharmaceuticals inmain rivers as well as their negative effects on the biota. Here we report the occurrence as well as the spatial and temporal variations of some common prescribed pharmaceuticals in the Suquía River basin (Córdoba, Argentina). We also report the bioconcentration of two of them in Gambusia affinis, a widely distributed fish species inhabiting the river basin. The influence of the wastewater treatment plant of Córdoba Citywas critical (up to 70 km downstream). Among 15 compounds analyzed, atenolol, carbamazepine and diclofenac were the most frequently detected (reaching sub μg L−1 levels), showing different distribution patterns. Bioconcentration of atenolol and carbamazepine was studied under laboratory controlled conditions. Estimated bioconcentration factors (BCFs) were: 0.13 and 0.08 L kg−1 upon exposure to 100 and 1000 μg L−1 atenolol in water, respectively; while BCFs were 0.7 and 0.9 L kg−1 when exposed to 10 and 100 μg L−1 carbamazepine, respectively. To the extent of our knowledge, this is the first report on pharmaceuticals in superficial waters of Argentina as well as the first<br />report on the bioaccumulation of atenolol in whole body fish.
publishDate 2014
dc.date.none.fl_str_mv 2014-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/8011
Valdés, María Eugenia; Amé, María Valeria; Bistoni, María de los Angeles; Wunderlin, Daniel Alberto; Occurrence and bioaccumulation of pharmaceuticals in a fish species inhabiting the Suquía River basin (Córdoba, Argentina); Elsevier Science; Science Of The Total Environment; 472; 2-2014; 389-396
0048-9697
url http://hdl.handle.net/11336/8011
identifier_str_mv Valdés, María Eugenia; Amé, María Valeria; Bistoni, María de los Angeles; Wunderlin, Daniel Alberto; Occurrence and bioaccumulation of pharmaceuticals in a fish species inhabiting the Suquía River basin (Córdoba, Argentina); Elsevier Science; Science Of The Total Environment; 472; 2-2014; 389-396
0048-9697
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://dx.doi.org/10.1016/j.scitotenv.2013.10.124
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0048969713013004
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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