Bactericidal and cytotoxic activities of polyphenol extracts from Solanum tuberosum spp tuberosum and spp andigena cultivars on Escherichia coli and Human neuroblastoma SH-SY5Y cel...

Autores
Silveyra, María Ximena; Lanteri, Maria Luciana; Damiano, Rocío Belén; Andreu, Adriana Balbina
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Potatoes (Solanum tuberosum L.) are a good source of dietary antioxidant polyphenols. This study investigated the potential antioxidant, bactericidal and cytotoxic activities in vitro of the phenolic compounds present in tubers of one S. tuberosum spp tuberosum (Summerside) and three S. tuberosum spp andigena (landraces Moradita, Waicha, Santa María) cultivars. Both the content of phenolic acids, chlorogenic acids (CGAs) being the most abundant, and the antioxidant activity were higher in extracts from skin than from flesh. Extracts from Moradita flesh and Summerside skin showed bactericidal activity against Escherichia coli ATCC 25922 but failed to inhibit pathogenic E. coli O157. Both extracts lack pigmentation but do contain 5-CGA, caffeic and ferulic acids. Positive control with gentamicin and commercial 5-CGA resulted in a complete inhibition of bacterial growth. In addition, all potato extracts and commercial 5-CGA diminished dose-dependently Human neuroblastoma SH-SY5Y cell viability. Skin extracts were more potent than flesh extracts. Among flesh extracts, Moradita was the most potent. Together, our results suggest that Moradita flesh could provide a desirable source of important health-promoting substances. Findings indicate that the biological activity of potato extracts is a combination of various bioactive compounds and contribute to the revalorization of potato as a functional food.
Fil: Silveyra, María Ximena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Biológicas. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Biológicas; Argentina
Fil: Lanteri, Maria Luciana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Biológicas. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Biológicas; Argentina
Fil: Damiano, Rocío Belén. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Andreu, Adriana Balbina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Biológicas. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Biológicas; Argentina
Materia
BACTERICIDAL
CYTOTOXIC
POLYPHENOL EXTRACTS
SOLANUM TUBEROSUM SPP TUBEROSUM
SOLANUM TUBEROSUM SPP ANDIGENA
ESCHERICHIA COLI
NEUROBLASTOMA SH-SY5Y
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/87398
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/87398
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Bactericidal and cytotoxic activities of polyphenol extracts from Solanum tuberosum spp tuberosum and spp andigena cultivars on Escherichia coli and Human neuroblastoma SH-SY5Y cells in vitroSilveyra, María XimenaLanteri, Maria LucianaDamiano, Rocío BelénAndreu, Adriana BalbinaBACTERICIDALCYTOTOXICPOLYPHENOL EXTRACTSSOLANUM TUBEROSUM SPP TUBEROSUMSOLANUM TUBEROSUM SPP ANDIGENAESCHERICHIA COLINEUROBLASTOMA SH-SY5Yhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Potatoes (Solanum tuberosum L.) are a good source of dietary antioxidant polyphenols. This study investigated the potential antioxidant, bactericidal and cytotoxic activities in vitro of the phenolic compounds present in tubers of one S. tuberosum spp tuberosum (Summerside) and three S. tuberosum spp andigena (landraces Moradita, Waicha, Santa María) cultivars. Both the content of phenolic acids, chlorogenic acids (CGAs) being the most abundant, and the antioxidant activity were higher in extracts from skin than from flesh. Extracts from Moradita flesh and Summerside skin showed bactericidal activity against Escherichia coli ATCC 25922 but failed to inhibit pathogenic E. coli O157. Both extracts lack pigmentation but do contain 5-CGA, caffeic and ferulic acids. Positive control with gentamicin and commercial 5-CGA resulted in a complete inhibition of bacterial growth. In addition, all potato extracts and commercial 5-CGA diminished dose-dependently Human neuroblastoma SH-SY5Y cell viability. Skin extracts were more potent than flesh extracts. Among flesh extracts, Moradita was the most potent. Together, our results suggest that Moradita flesh could provide a desirable source of important health-promoting substances. Findings indicate that the biological activity of potato extracts is a combination of various bioactive compounds and contribute to the revalorization of potato as a functional food.Fil: Silveyra, María Ximena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Biológicas. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Biológicas; ArgentinaFil: Lanteri, Maria Luciana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Biológicas. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Biológicas; ArgentinaFil: Damiano, Rocío Belén. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Andreu, Adriana Balbina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Biológicas. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Biológicas; ArgentinaHindawi Limited2018-03-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/87398Silveyra, María Ximena; Lanteri, Maria Luciana; Damiano, Rocío Belén; Andreu, Adriana Balbina; Bactericidal and cytotoxic activities of polyphenol extracts from Solanum tuberosum spp tuberosum and spp andigena cultivars on Escherichia coli and Human neuroblastoma SH-SY5Y cells in vitro; Hindawi Limited; Journal of Nutrition and Metabolism; 22-3-2018; 1-102090-0724CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.hindawi.com/journals/jnme/2018/8073679/info:eu-repo/semantics/altIdentifier/doi/10.1155/2018/8073679info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:53:29Zoai:ri.conicet.gov.ar:11336/87398instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:53:29.367CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Bactericidal and cytotoxic activities of polyphenol extracts from Solanum tuberosum spp tuberosum and spp andigena cultivars on Escherichia coli and Human neuroblastoma SH-SY5Y cells in vitro
title Bactericidal and cytotoxic activities of polyphenol extracts from Solanum tuberosum spp tuberosum and spp andigena cultivars on Escherichia coli and Human neuroblastoma SH-SY5Y cells in vitro
spellingShingle Bactericidal and cytotoxic activities of polyphenol extracts from Solanum tuberosum spp tuberosum and spp andigena cultivars on Escherichia coli and Human neuroblastoma SH-SY5Y cells in vitro
Silveyra, María Ximena
BACTERICIDAL
CYTOTOXIC
POLYPHENOL EXTRACTS
SOLANUM TUBEROSUM SPP TUBEROSUM
SOLANUM TUBEROSUM SPP ANDIGENA
ESCHERICHIA COLI
NEUROBLASTOMA SH-SY5Y
title_short Bactericidal and cytotoxic activities of polyphenol extracts from Solanum tuberosum spp tuberosum and spp andigena cultivars on Escherichia coli and Human neuroblastoma SH-SY5Y cells in vitro
title_full Bactericidal and cytotoxic activities of polyphenol extracts from Solanum tuberosum spp tuberosum and spp andigena cultivars on Escherichia coli and Human neuroblastoma SH-SY5Y cells in vitro
title_fullStr Bactericidal and cytotoxic activities of polyphenol extracts from Solanum tuberosum spp tuberosum and spp andigena cultivars on Escherichia coli and Human neuroblastoma SH-SY5Y cells in vitro
title_full_unstemmed Bactericidal and cytotoxic activities of polyphenol extracts from Solanum tuberosum spp tuberosum and spp andigena cultivars on Escherichia coli and Human neuroblastoma SH-SY5Y cells in vitro
title_sort Bactericidal and cytotoxic activities of polyphenol extracts from Solanum tuberosum spp tuberosum and spp andigena cultivars on Escherichia coli and Human neuroblastoma SH-SY5Y cells in vitro
dc.creator.none.fl_str_mv Silveyra, María Ximena
Lanteri, Maria Luciana
Damiano, Rocío Belén
Andreu, Adriana Balbina
author Silveyra, María Ximena
author_facet Silveyra, María Ximena
Lanteri, Maria Luciana
Damiano, Rocío Belén
Andreu, Adriana Balbina
author_role author
author2 Lanteri, Maria Luciana
Damiano, Rocío Belén
Andreu, Adriana Balbina
author2_role author
author
author
dc.subject.none.fl_str_mv BACTERICIDAL
CYTOTOXIC
POLYPHENOL EXTRACTS
SOLANUM TUBEROSUM SPP TUBEROSUM
SOLANUM TUBEROSUM SPP ANDIGENA
ESCHERICHIA COLI
NEUROBLASTOMA SH-SY5Y
topic BACTERICIDAL
CYTOTOXIC
POLYPHENOL EXTRACTS
SOLANUM TUBEROSUM SPP TUBEROSUM
SOLANUM TUBEROSUM SPP ANDIGENA
ESCHERICHIA COLI
NEUROBLASTOMA SH-SY5Y
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Potatoes (Solanum tuberosum L.) are a good source of dietary antioxidant polyphenols. This study investigated the potential antioxidant, bactericidal and cytotoxic activities in vitro of the phenolic compounds present in tubers of one S. tuberosum spp tuberosum (Summerside) and three S. tuberosum spp andigena (landraces Moradita, Waicha, Santa María) cultivars. Both the content of phenolic acids, chlorogenic acids (CGAs) being the most abundant, and the antioxidant activity were higher in extracts from skin than from flesh. Extracts from Moradita flesh and Summerside skin showed bactericidal activity against Escherichia coli ATCC 25922 but failed to inhibit pathogenic E. coli O157. Both extracts lack pigmentation but do contain 5-CGA, caffeic and ferulic acids. Positive control with gentamicin and commercial 5-CGA resulted in a complete inhibition of bacterial growth. In addition, all potato extracts and commercial 5-CGA diminished dose-dependently Human neuroblastoma SH-SY5Y cell viability. Skin extracts were more potent than flesh extracts. Among flesh extracts, Moradita was the most potent. Together, our results suggest that Moradita flesh could provide a desirable source of important health-promoting substances. Findings indicate that the biological activity of potato extracts is a combination of various bioactive compounds and contribute to the revalorization of potato as a functional food.
Fil: Silveyra, María Ximena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Biológicas. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Biológicas; Argentina
Fil: Lanteri, Maria Luciana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Biológicas. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Biológicas; Argentina
Fil: Damiano, Rocío Belén. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Andreu, Adriana Balbina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Biológicas. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Biológicas; Argentina
description Potatoes (Solanum tuberosum L.) are a good source of dietary antioxidant polyphenols. This study investigated the potential antioxidant, bactericidal and cytotoxic activities in vitro of the phenolic compounds present in tubers of one S. tuberosum spp tuberosum (Summerside) and three S. tuberosum spp andigena (landraces Moradita, Waicha, Santa María) cultivars. Both the content of phenolic acids, chlorogenic acids (CGAs) being the most abundant, and the antioxidant activity were higher in extracts from skin than from flesh. Extracts from Moradita flesh and Summerside skin showed bactericidal activity against Escherichia coli ATCC 25922 but failed to inhibit pathogenic E. coli O157. Both extracts lack pigmentation but do contain 5-CGA, caffeic and ferulic acids. Positive control with gentamicin and commercial 5-CGA resulted in a complete inhibition of bacterial growth. In addition, all potato extracts and commercial 5-CGA diminished dose-dependently Human neuroblastoma SH-SY5Y cell viability. Skin extracts were more potent than flesh extracts. Among flesh extracts, Moradita was the most potent. Together, our results suggest that Moradita flesh could provide a desirable source of important health-promoting substances. Findings indicate that the biological activity of potato extracts is a combination of various bioactive compounds and contribute to the revalorization of potato as a functional food.
publishDate 2018
dc.date.none.fl_str_mv 2018-03-22
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/87398
Silveyra, María Ximena; Lanteri, Maria Luciana; Damiano, Rocío Belén; Andreu, Adriana Balbina; Bactericidal and cytotoxic activities of polyphenol extracts from Solanum tuberosum spp tuberosum and spp andigena cultivars on Escherichia coli and Human neuroblastoma SH-SY5Y cells in vitro; Hindawi Limited; Journal of Nutrition and Metabolism; 22-3-2018; 1-10
2090-0724
CONICET Digital
CONICET
url http://hdl.handle.net/11336/87398
identifier_str_mv Silveyra, María Ximena; Lanteri, Maria Luciana; Damiano, Rocío Belén; Andreu, Adriana Balbina; Bactericidal and cytotoxic activities of polyphenol extracts from Solanum tuberosum spp tuberosum and spp andigena cultivars on Escherichia coli and Human neuroblastoma SH-SY5Y cells in vitro; Hindawi Limited; Journal of Nutrition and Metabolism; 22-3-2018; 1-10
2090-0724
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.hindawi.com/journals/jnme/2018/8073679/
info:eu-repo/semantics/altIdentifier/doi/10.1155/2018/8073679
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Hindawi Limited
publisher.none.fl_str_mv Hindawi Limited
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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