How Safe Is Moderate Alcohol Consumption in Overweight and Obese Individuals?

Autores
Sookoian, Silvia Cristina; Pirola, Carlos José
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The prevalence of nonalcoholic fatty liver disease (NAFLD) has reached global epidemic proportions,1 paralleling that of the increasing trends in the prevalence of obesity and type 2 diabetes (T2D). In fact, obesity is one of the most frequently associated comorbidities of NAFLD,2 and, furthermore, NAFLD and obesity integrate the myriad risk factors for cardiovascular disease (CVD) clustered in the metabolic syndrome (MetS). By definition, NAFLD is characterized by abnormal liver fat accumulation in the absence of significant alcohol consumption and other causes of secondary hepatic steatosis. Once diagnosed, the treatment of NAFLD is complex and often requires pharmacologic intervention to control associated risk factors and/or lifestyle modifications. Conflicting results on whether social or moderate alcohol consumption (MAC) is detrimental or beneficial leave physicians uncertain as to whether or not to apply tight restrictions or allow low levels of social alcohol use for potential health benefit.
Fil: Sookoian, Silvia Cristina. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Pirola, Carlos José. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Alcohol Consumption
Fibrosis
Mendelian Randomization
Nafld
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/38760
Acceder
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network_name_str CONICET Digital (CONICET)
spelling How Safe Is Moderate Alcohol Consumption in Overweight and Obese Individuals?Sookoian, Silvia CristinaPirola, Carlos JoséAlcohol ConsumptionFibrosisMendelian RandomizationNafldhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3The prevalence of nonalcoholic fatty liver disease (NAFLD) has reached global epidemic proportions,1 paralleling that of the increasing trends in the prevalence of obesity and type 2 diabetes (T2D). In fact, obesity is one of the most frequently associated comorbidities of NAFLD,2 and, furthermore, NAFLD and obesity integrate the myriad risk factors for cardiovascular disease (CVD) clustered in the metabolic syndrome (MetS). By definition, NAFLD is characterized by abnormal liver fat accumulation in the absence of significant alcohol consumption and other causes of secondary hepatic steatosis. Once diagnosed, the treatment of NAFLD is complex and often requires pharmacologic intervention to control associated risk factors and/or lifestyle modifications. Conflicting results on whether social or moderate alcohol consumption (MAC) is detrimental or beneficial leave physicians uncertain as to whether or not to apply tight restrictions or allow low levels of social alcohol use for potential health benefit.Fil: Sookoian, Silvia Cristina. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Pirola, Carlos José. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaW B Saunders Co-Elsevier Inc2016-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/38760Sookoian, Silvia Cristina; Pirola, Carlos José; How Safe Is Moderate Alcohol Consumption in Overweight and Obese Individuals?; W B Saunders Co-Elsevier Inc; Gastroenterology; 150; 8; 6-2016; 1698-17030016-5085CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1053/j.gastro.2016.01.002info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0016508516000056info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:51:13Zoai:ri.conicet.gov.ar:11336/38760instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:51:13.38CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv How Safe Is Moderate Alcohol Consumption in Overweight and Obese Individuals?
title How Safe Is Moderate Alcohol Consumption in Overweight and Obese Individuals?
spellingShingle How Safe Is Moderate Alcohol Consumption in Overweight and Obese Individuals?
Sookoian, Silvia Cristina
Alcohol Consumption
Fibrosis
Mendelian Randomization
Nafld
title_short How Safe Is Moderate Alcohol Consumption in Overweight and Obese Individuals?
title_full How Safe Is Moderate Alcohol Consumption in Overweight and Obese Individuals?
title_fullStr How Safe Is Moderate Alcohol Consumption in Overweight and Obese Individuals?
title_full_unstemmed How Safe Is Moderate Alcohol Consumption in Overweight and Obese Individuals?
title_sort How Safe Is Moderate Alcohol Consumption in Overweight and Obese Individuals?
dc.creator.none.fl_str_mv Sookoian, Silvia Cristina
Pirola, Carlos José
author Sookoian, Silvia Cristina
author_facet Sookoian, Silvia Cristina
Pirola, Carlos José
author_role author
author2 Pirola, Carlos José
author2_role author
dc.subject.none.fl_str_mv Alcohol Consumption
Fibrosis
Mendelian Randomization
Nafld
topic Alcohol Consumption
Fibrosis
Mendelian Randomization
Nafld
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The prevalence of nonalcoholic fatty liver disease (NAFLD) has reached global epidemic proportions,1 paralleling that of the increasing trends in the prevalence of obesity and type 2 diabetes (T2D). In fact, obesity is one of the most frequently associated comorbidities of NAFLD,2 and, furthermore, NAFLD and obesity integrate the myriad risk factors for cardiovascular disease (CVD) clustered in the metabolic syndrome (MetS). By definition, NAFLD is characterized by abnormal liver fat accumulation in the absence of significant alcohol consumption and other causes of secondary hepatic steatosis. Once diagnosed, the treatment of NAFLD is complex and often requires pharmacologic intervention to control associated risk factors and/or lifestyle modifications. Conflicting results on whether social or moderate alcohol consumption (MAC) is detrimental or beneficial leave physicians uncertain as to whether or not to apply tight restrictions or allow low levels of social alcohol use for potential health benefit.
Fil: Sookoian, Silvia Cristina. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Pirola, Carlos José. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description The prevalence of nonalcoholic fatty liver disease (NAFLD) has reached global epidemic proportions,1 paralleling that of the increasing trends in the prevalence of obesity and type 2 diabetes (T2D). In fact, obesity is one of the most frequently associated comorbidities of NAFLD,2 and, furthermore, NAFLD and obesity integrate the myriad risk factors for cardiovascular disease (CVD) clustered in the metabolic syndrome (MetS). By definition, NAFLD is characterized by abnormal liver fat accumulation in the absence of significant alcohol consumption and other causes of secondary hepatic steatosis. Once diagnosed, the treatment of NAFLD is complex and often requires pharmacologic intervention to control associated risk factors and/or lifestyle modifications. Conflicting results on whether social or moderate alcohol consumption (MAC) is detrimental or beneficial leave physicians uncertain as to whether or not to apply tight restrictions or allow low levels of social alcohol use for potential health benefit.
publishDate 2016
dc.date.none.fl_str_mv 2016-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/38760
Sookoian, Silvia Cristina; Pirola, Carlos José; How Safe Is Moderate Alcohol Consumption in Overweight and Obese Individuals?; W B Saunders Co-Elsevier Inc; Gastroenterology; 150; 8; 6-2016; 1698-1703
0016-5085
CONICET Digital
CONICET
url http://hdl.handle.net/11336/38760
identifier_str_mv Sookoian, Silvia Cristina; Pirola, Carlos José; How Safe Is Moderate Alcohol Consumption in Overweight and Obese Individuals?; W B Saunders Co-Elsevier Inc; Gastroenterology; 150; 8; 6-2016; 1698-1703
0016-5085
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1053/j.gastro.2016.01.002
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0016508516000056
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv W B Saunders Co-Elsevier Inc
publisher.none.fl_str_mv W B Saunders Co-Elsevier Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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