Hepatitis E virus in children and adolescents living in an urban environment in central Argentina: An explorative study

Autores
Cervella, Lorena L.; García Oro, Cecilia; Fantilli, Anabella Clara; Di Cola Bucciarelli, Guadalupe; Martínez Wassaf, Maribel G.; Oropeza, Gabriela; Castro, Gonzalo Manuel; Sicilia, Paola; Ré, Viviana Elizabeth; Pisano, María Belén
Año de publicación
2024
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In Argentina, circulation of hepatitis E virus (HEV) genotype 3 has been described, producing sporadic cases of acute and chronic hepatitis. Limited information is available regarding HEV infection in children, so we aimed to investigate this virus in a pediatric population from the country. Serum samples from Argentine children (0–18 years old) (n = 213) were studied for IgG anti-HEV, IgM anti-HEV and RNA-HEV: 202 samples belonged to individuals attending health-care centers for routine check-ups, and 11 samples from patients with acute hepatitis of unknown etiology. Seropositivity for IgG anti-HEV was 1.49 % (3/202). One sample from an 18-years-old female patient with acute hepatitis tested positive for IgM anti-HEV detection, negative for IgG anti-HEV and RNA-HEV, but also positive for IgM anti-EBV. The HEV prevalence was low and showed circulation among children in central Argentina.
Fil: Cervella, Lorena L.. Hospital Infantil Municipal; Argentina
Fil: García Oro, Cecilia. Hospital Infantil Municipal; Argentina
Fil: Fantilli, Anabella Clara. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Di Cola Bucciarelli, Guadalupe. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; Argentina
Fil: Martínez Wassaf, Maribel G.. No especifíca;
Fil: Oropeza, Gabriela. Hospital Infantil Municipal; Argentina
Fil: Castro, Gonzalo Manuel. Gobierno de la Provincia de Cordoba. Ministerio de Salud. Laboratorio Central de la Provincia.; . Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Sicilia, Paola. Gobierno de la Provincia de Cordoba. Ministerio de Salud. Laboratorio Central de la Provincia.;
Fil: Ré, Viviana Elizabeth. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Pisano, María Belén. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; Argentina
Materia
HEV
ARGENTINA
CHILDREN
INFECTION
COINFECTION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/238607
Acceder
id CONICETDig_15997dc416a6b12df93943aae049f4a9
oai_identifier_str oai:ri.conicet.gov.ar:11336/238607
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Hepatitis E virus in children and adolescents living in an urban environment in central Argentina: An explorative studyCervella, Lorena L.García Oro, CeciliaFantilli, Anabella ClaraDi Cola Bucciarelli, GuadalupeMartínez Wassaf, Maribel G.Oropeza, GabrielaCastro, Gonzalo ManuelSicilia, PaolaRé, Viviana ElizabethPisano, María BelénHEVARGENTINACHILDRENINFECTIONCOINFECTIONhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1In Argentina, circulation of hepatitis E virus (HEV) genotype 3 has been described, producing sporadic cases of acute and chronic hepatitis. Limited information is available regarding HEV infection in children, so we aimed to investigate this virus in a pediatric population from the country. Serum samples from Argentine children (0–18 years old) (n = 213) were studied for IgG anti-HEV, IgM anti-HEV and RNA-HEV: 202 samples belonged to individuals attending health-care centers for routine check-ups, and 11 samples from patients with acute hepatitis of unknown etiology. Seropositivity for IgG anti-HEV was 1.49 % (3/202). One sample from an 18-years-old female patient with acute hepatitis tested positive for IgM anti-HEV detection, negative for IgG anti-HEV and RNA-HEV, but also positive for IgM anti-EBV. The HEV prevalence was low and showed circulation among children in central Argentina.Fil: Cervella, Lorena L.. Hospital Infantil Municipal; ArgentinaFil: García Oro, Cecilia. Hospital Infantil Municipal; ArgentinaFil: Fantilli, Anabella Clara. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Di Cola Bucciarelli, Guadalupe. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; ArgentinaFil: Martínez Wassaf, Maribel G.. No especifíca;Fil: Oropeza, Gabriela. Hospital Infantil Municipal; ArgentinaFil: Castro, Gonzalo Manuel. Gobierno de la Provincia de Cordoba. Ministerio de Salud. Laboratorio Central de la Provincia.; . Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Sicilia, Paola. Gobierno de la Provincia de Cordoba. Ministerio de Salud. Laboratorio Central de la Provincia.;Fil: Ré, Viviana Elizabeth. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Pisano, María Belén. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; ArgentinaElsevier2024-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/238607Cervella, Lorena L.; García Oro, Cecilia; Fantilli, Anabella Clara; Di Cola Bucciarelli, Guadalupe; Martínez Wassaf, Maribel G.; et al.; Hepatitis E virus in children and adolescents living in an urban environment in central Argentina: An explorative study; Elsevier; Heliyon; 10; 11; 6-2024; 1-62405-8440CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S2405844024083154info:eu-repo/semantics/altIdentifier/doi/10.1016/j.heliyon.2024.e32284info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:34:00Zoai:ri.conicet.gov.ar:11336/238607instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:34:01.107CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Hepatitis E virus in children and adolescents living in an urban environment in central Argentina: An explorative study
title Hepatitis E virus in children and adolescents living in an urban environment in central Argentina: An explorative study
spellingShingle Hepatitis E virus in children and adolescents living in an urban environment in central Argentina: An explorative study
Cervella, Lorena L.
HEV
ARGENTINA
CHILDREN
INFECTION
COINFECTION
title_short Hepatitis E virus in children and adolescents living in an urban environment in central Argentina: An explorative study
title_full Hepatitis E virus in children and adolescents living in an urban environment in central Argentina: An explorative study
title_fullStr Hepatitis E virus in children and adolescents living in an urban environment in central Argentina: An explorative study
title_full_unstemmed Hepatitis E virus in children and adolescents living in an urban environment in central Argentina: An explorative study
title_sort Hepatitis E virus in children and adolescents living in an urban environment in central Argentina: An explorative study
dc.creator.none.fl_str_mv Cervella, Lorena L.
García Oro, Cecilia
Fantilli, Anabella Clara
Di Cola Bucciarelli, Guadalupe
Martínez Wassaf, Maribel G.
Oropeza, Gabriela
Castro, Gonzalo Manuel
Sicilia, Paola
Ré, Viviana Elizabeth
Pisano, María Belén
author Cervella, Lorena L.
author_facet Cervella, Lorena L.
García Oro, Cecilia
Fantilli, Anabella Clara
Di Cola Bucciarelli, Guadalupe
Martínez Wassaf, Maribel G.
Oropeza, Gabriela
Castro, Gonzalo Manuel
Sicilia, Paola
Ré, Viviana Elizabeth
Pisano, María Belén
author_role author
author2 García Oro, Cecilia
Fantilli, Anabella Clara
Di Cola Bucciarelli, Guadalupe
Martínez Wassaf, Maribel G.
Oropeza, Gabriela
Castro, Gonzalo Manuel
Sicilia, Paola
Ré, Viviana Elizabeth
Pisano, María Belén
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv HEV
ARGENTINA
CHILDREN
INFECTION
COINFECTION
topic HEV
ARGENTINA
CHILDREN
INFECTION
COINFECTION
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv In Argentina, circulation of hepatitis E virus (HEV) genotype 3 has been described, producing sporadic cases of acute and chronic hepatitis. Limited information is available regarding HEV infection in children, so we aimed to investigate this virus in a pediatric population from the country. Serum samples from Argentine children (0–18 years old) (n = 213) were studied for IgG anti-HEV, IgM anti-HEV and RNA-HEV: 202 samples belonged to individuals attending health-care centers for routine check-ups, and 11 samples from patients with acute hepatitis of unknown etiology. Seropositivity for IgG anti-HEV was 1.49 % (3/202). One sample from an 18-years-old female patient with acute hepatitis tested positive for IgM anti-HEV detection, negative for IgG anti-HEV and RNA-HEV, but also positive for IgM anti-EBV. The HEV prevalence was low and showed circulation among children in central Argentina.
Fil: Cervella, Lorena L.. Hospital Infantil Municipal; Argentina
Fil: García Oro, Cecilia. Hospital Infantil Municipal; Argentina
Fil: Fantilli, Anabella Clara. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Di Cola Bucciarelli, Guadalupe. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; Argentina
Fil: Martínez Wassaf, Maribel G.. No especifíca;
Fil: Oropeza, Gabriela. Hospital Infantil Municipal; Argentina
Fil: Castro, Gonzalo Manuel. Gobierno de la Provincia de Cordoba. Ministerio de Salud. Laboratorio Central de la Provincia.; . Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Sicilia, Paola. Gobierno de la Provincia de Cordoba. Ministerio de Salud. Laboratorio Central de la Provincia.;
Fil: Ré, Viviana Elizabeth. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Pisano, María Belén. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; Argentina
description In Argentina, circulation of hepatitis E virus (HEV) genotype 3 has been described, producing sporadic cases of acute and chronic hepatitis. Limited information is available regarding HEV infection in children, so we aimed to investigate this virus in a pediatric population from the country. Serum samples from Argentine children (0–18 years old) (n = 213) were studied for IgG anti-HEV, IgM anti-HEV and RNA-HEV: 202 samples belonged to individuals attending health-care centers for routine check-ups, and 11 samples from patients with acute hepatitis of unknown etiology. Seropositivity for IgG anti-HEV was 1.49 % (3/202). One sample from an 18-years-old female patient with acute hepatitis tested positive for IgM anti-HEV detection, negative for IgG anti-HEV and RNA-HEV, but also positive for IgM anti-EBV. The HEV prevalence was low and showed circulation among children in central Argentina.
publishDate 2024
dc.date.none.fl_str_mv 2024-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/238607
Cervella, Lorena L.; García Oro, Cecilia; Fantilli, Anabella Clara; Di Cola Bucciarelli, Guadalupe; Martínez Wassaf, Maribel G.; et al.; Hepatitis E virus in children and adolescents living in an urban environment in central Argentina: An explorative study; Elsevier; Heliyon; 10; 11; 6-2024; 1-6
2405-8440
CONICET Digital
CONICET
url http://hdl.handle.net/11336/238607
identifier_str_mv Cervella, Lorena L.; García Oro, Cecilia; Fantilli, Anabella Clara; Di Cola Bucciarelli, Guadalupe; Martínez Wassaf, Maribel G.; et al.; Hepatitis E virus in children and adolescents living in an urban environment in central Argentina: An explorative study; Elsevier; Heliyon; 10; 11; 6-2024; 1-6
2405-8440
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S2405844024083154
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.heliyon.2024.e32284
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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