An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease

Autores
Sun, Dan Qin; Targher, Giovanni; Byrne, Christopher D.; Wheeler, David C.; Wong, Vincent Wai Sun; Fan, Jian Gao; Tilg, Herbert; Yuan, Wei Jie; Wanner, Christoph; Gao, Xin; Long, Michelle T.; Kanbay, Mehmet; Nguyen, Mindie H.; Navaneethan, Sankar D.; Yilmaz, Yusuf; Huang, Yuli; Gani, Rino A.; Marzuillo, Pierluigi; Boursier, Jérôme; Zhang, Huijie; Jung, Chan Young; Chai, Jin; Valenti, Luca; Papatheodoridis, George; Sookoian, Silvia Cristina; Chunsun, Dai; Eslam, Mohammed; Wei, Lai; George, Jacob; Zheng, Ming Hua
Año de publicación
2023
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: With the rising global prevalence of fatty liver disease related to metabolic dysfunction, the association of this common liver condition with chronic kidney disease (CKD) has become increasingly evident. In 2020, the more inclusive term metabolic dysfunction-associated fatty liver disease (MAFLD) was proposed to replace the term non-alcoholic fatty liver disease (NAFLD). The observed association between MAFLD and CKD and our understanding that CKD can be a consequence of underlying metabolic dysfunction support the notion that individuals with MAFLD are at higher risk of having and developing CKD compared with those without MAFLD. However, to date, there is no appropriate guidance on CKD in individuals with MAFLD. Furthermore, there has been little attention paid to the link between MAFLD and CKD in the Nephrology community. Methods and Results: Using a Delphi-based approach, a multidisciplinary panel of 50 international experts from 26 countries reached a consensus on some of the open research questions regarding the link between MAFLD and CKD. Conclusions: This Delphi-based consensus statement provided guidance on the epidemiology, mechanisms, management and treatment of MAFLD and CKD, as well as the relationship between the severity of MAFLD and risk of CKD, which establish a framework for the early prevention and management of these two common and interconnected diseases.
Fil: Sun, Dan Qin. Jiangnan University Medical Center; China. Nantong University; China
Fil: Targher, Giovanni. Azienda Ospedaliera Universitaria Integrata Verona; Italia
Fil: Byrne, Christopher D.. University of Southampton; Reino Unido
Fil: Wheeler, David C.. University College London; Estados Unidos
Fil: Wong, Vincent Wai Sun. Chinese University of Hong Kong; China
Fil: Fan, Jian Gao. Shanghai Jiao Tong University; China
Fil: Tilg, Herbert. Medical University Innsbruck; Austria
Fil: Yuan, Wei Jie. Shanghai Jiao Tong University; China
Fil: Wanner, Christoph. Würzburg University Clinic; Alemania
Fil: Gao, Xin. Fudan University; China
Fil: Long, Michelle T.. Boston University School of Medicine; Estados Unidos
Fil: Kanbay, Mehmet. Koc University School of Medicine; Turquía
Fil: Nguyen, Mindie H.. Stanford University Medical Center; Estados Unidos
Fil: Navaneethan, Sankar D.. Baylor College of Medicine; Estados Unidos
Fil: Yilmaz, Yusuf. Marmara University; Turquía. Recep Tayyip Erdoğan University; Turquía
Fil: Huang, Yuli. Southern Medical University; China
Fil: Gani, Rino A.. Universitas Indonesia; Indonesia
Fil: Marzuillo, Pierluigi. Università della Campania “Luigi Vanvitelli”; Italia
Fil: Boursier, Jérôme. Angers University; Francia
Fil: Zhang, Huijie. Southern Medical University; China
Fil: Jung, Chan Young. Yonsei University; Corea del Sur
Fil: Chai, Jin. Army Medical University; China
Fil: Valenti, Luca. Università degli Studi di Milano; Italia
Fil: Papatheodoridis, George. Kapodistrian University of Athens; Grecia
Fil: Sookoian, Silvia Cristina. Centro de Investigacion Traslacional En Salud (cenitres) ; Facultad de Cs. de la Salud ; Universidad Maimonides; . Universidad Abierta Interamericana; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Chunsun, Dai. Nanjing Medical University; China
Fil: Eslam, Mohammed. University of Sydney; Australia
Fil: Wei, Lai. Tsinghua University; China
Fil: George, Jacob. University of Sydney; Australia
Fil: Zheng, Ming Hua. Wenzhou Medical University; China
Materia
NAFLD
NASH
CKD
CONSENSUS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/221030

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network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney diseaseSun, Dan QinTargher, GiovanniByrne, Christopher D.Wheeler, David C.Wong, Vincent Wai SunFan, Jian GaoTilg, HerbertYuan, Wei JieWanner, ChristophGao, XinLong, Michelle T.Kanbay, MehmetNguyen, Mindie H.Navaneethan, Sankar D.Yilmaz, YusufHuang, YuliGani, Rino A.Marzuillo, PierluigiBoursier, JérômeZhang, HuijieJung, Chan YoungChai, JinValenti, LucaPapatheodoridis, GeorgeSookoian, Silvia CristinaChunsun, DaiEslam, MohammedWei, LaiGeorge, JacobZheng, Ming HuaNAFLDNASHCKDCONSENSUShttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Background: With the rising global prevalence of fatty liver disease related to metabolic dysfunction, the association of this common liver condition with chronic kidney disease (CKD) has become increasingly evident. In 2020, the more inclusive term metabolic dysfunction-associated fatty liver disease (MAFLD) was proposed to replace the term non-alcoholic fatty liver disease (NAFLD). The observed association between MAFLD and CKD and our understanding that CKD can be a consequence of underlying metabolic dysfunction support the notion that individuals with MAFLD are at higher risk of having and developing CKD compared with those without MAFLD. However, to date, there is no appropriate guidance on CKD in individuals with MAFLD. Furthermore, there has been little attention paid to the link between MAFLD and CKD in the Nephrology community. Methods and Results: Using a Delphi-based approach, a multidisciplinary panel of 50 international experts from 26 countries reached a consensus on some of the open research questions regarding the link between MAFLD and CKD. Conclusions: This Delphi-based consensus statement provided guidance on the epidemiology, mechanisms, management and treatment of MAFLD and CKD, as well as the relationship between the severity of MAFLD and risk of CKD, which establish a framework for the early prevention and management of these two common and interconnected diseases.Fil: Sun, Dan Qin. Jiangnan University Medical Center; China. Nantong University; ChinaFil: Targher, Giovanni. Azienda Ospedaliera Universitaria Integrata Verona; ItaliaFil: Byrne, Christopher D.. University of Southampton; Reino UnidoFil: Wheeler, David C.. University College London; Estados UnidosFil: Wong, Vincent Wai Sun. Chinese University of Hong Kong; ChinaFil: Fan, Jian Gao. Shanghai Jiao Tong University; ChinaFil: Tilg, Herbert. Medical University Innsbruck; AustriaFil: Yuan, Wei Jie. Shanghai Jiao Tong University; ChinaFil: Wanner, Christoph. Würzburg University Clinic; AlemaniaFil: Gao, Xin. Fudan University; ChinaFil: Long, Michelle T.. Boston University School of Medicine; Estados UnidosFil: Kanbay, Mehmet. Koc University School of Medicine; TurquíaFil: Nguyen, Mindie H.. Stanford University Medical Center; Estados UnidosFil: Navaneethan, Sankar D.. Baylor College of Medicine; Estados UnidosFil: Yilmaz, Yusuf. Marmara University; Turquía. Recep Tayyip Erdoğan University; TurquíaFil: Huang, Yuli. Southern Medical University; ChinaFil: Gani, Rino A.. Universitas Indonesia; IndonesiaFil: Marzuillo, Pierluigi. Università della Campania “Luigi Vanvitelli”; ItaliaFil: Boursier, Jérôme. Angers University; FranciaFil: Zhang, Huijie. Southern Medical University; ChinaFil: Jung, Chan Young. Yonsei University; Corea del SurFil: Chai, Jin. Army Medical University; ChinaFil: Valenti, Luca. Università degli Studi di Milano; ItaliaFil: Papatheodoridis, George. Kapodistrian University of Athens; GreciaFil: Sookoian, Silvia Cristina. Centro de Investigacion Traslacional En Salud (cenitres) ; Facultad de Cs. de la Salud ; Universidad Maimonides; . Universidad Abierta Interamericana; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Chunsun, Dai. Nanjing Medical University; ChinaFil: Eslam, Mohammed. University of Sydney; AustraliaFil: Wei, Lai. Tsinghua University; ChinaFil: George, Jacob. University of Sydney; AustraliaFil: Zheng, Ming Hua. Wenzhou Medical University; ChinaAME Publishing Company2023-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/221030Sun, Dan Qin; Targher, Giovanni; Byrne, Christopher D.; Wheeler, David C.; Wong, Vincent Wai Sun; et al.; An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease; AME Publishing Company; Hepatobiliary Surgery and Nutrition; 12; 3; 6-2023; 386-4032304-38812304-389XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://hbsn.amegroups.com/article/view/110403/htmlinfo:eu-repo/semantics/altIdentifier/doi/10.21037/hbsn-22-421info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:40:57Zoai:ri.conicet.gov.ar:11336/221030instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:40:58.156CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease
title An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease
spellingShingle An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease
Sun, Dan Qin
NAFLD
NASH
CKD
CONSENSUS
title_short An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease
title_full An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease
title_fullStr An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease
title_full_unstemmed An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease
title_sort An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease
dc.creator.none.fl_str_mv Sun, Dan Qin
Targher, Giovanni
Byrne, Christopher D.
Wheeler, David C.
Wong, Vincent Wai Sun
Fan, Jian Gao
Tilg, Herbert
Yuan, Wei Jie
Wanner, Christoph
Gao, Xin
Long, Michelle T.
Kanbay, Mehmet
Nguyen, Mindie H.
Navaneethan, Sankar D.
Yilmaz, Yusuf
Huang, Yuli
Gani, Rino A.
Marzuillo, Pierluigi
Boursier, Jérôme
Zhang, Huijie
Jung, Chan Young
Chai, Jin
Valenti, Luca
Papatheodoridis, George
Sookoian, Silvia Cristina
Chunsun, Dai
Eslam, Mohammed
Wei, Lai
George, Jacob
Zheng, Ming Hua
author Sun, Dan Qin
author_facet Sun, Dan Qin
Targher, Giovanni
Byrne, Christopher D.
Wheeler, David C.
Wong, Vincent Wai Sun
Fan, Jian Gao
Tilg, Herbert
Yuan, Wei Jie
Wanner, Christoph
Gao, Xin
Long, Michelle T.
Kanbay, Mehmet
Nguyen, Mindie H.
Navaneethan, Sankar D.
Yilmaz, Yusuf
Huang, Yuli
Gani, Rino A.
Marzuillo, Pierluigi
Boursier, Jérôme
Zhang, Huijie
Jung, Chan Young
Chai, Jin
Valenti, Luca
Papatheodoridis, George
Sookoian, Silvia Cristina
Chunsun, Dai
Eslam, Mohammed
Wei, Lai
George, Jacob
Zheng, Ming Hua
author_role author
author2 Targher, Giovanni
Byrne, Christopher D.
Wheeler, David C.
Wong, Vincent Wai Sun
Fan, Jian Gao
Tilg, Herbert
Yuan, Wei Jie
Wanner, Christoph
Gao, Xin
Long, Michelle T.
Kanbay, Mehmet
Nguyen, Mindie H.
Navaneethan, Sankar D.
Yilmaz, Yusuf
Huang, Yuli
Gani, Rino A.
Marzuillo, Pierluigi
Boursier, Jérôme
Zhang, Huijie
Jung, Chan Young
Chai, Jin
Valenti, Luca
Papatheodoridis, George
Sookoian, Silvia Cristina
Chunsun, Dai
Eslam, Mohammed
Wei, Lai
George, Jacob
Zheng, Ming Hua
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv NAFLD
NASH
CKD
CONSENSUS
topic NAFLD
NASH
CKD
CONSENSUS
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Background: With the rising global prevalence of fatty liver disease related to metabolic dysfunction, the association of this common liver condition with chronic kidney disease (CKD) has become increasingly evident. In 2020, the more inclusive term metabolic dysfunction-associated fatty liver disease (MAFLD) was proposed to replace the term non-alcoholic fatty liver disease (NAFLD). The observed association between MAFLD and CKD and our understanding that CKD can be a consequence of underlying metabolic dysfunction support the notion that individuals with MAFLD are at higher risk of having and developing CKD compared with those without MAFLD. However, to date, there is no appropriate guidance on CKD in individuals with MAFLD. Furthermore, there has been little attention paid to the link between MAFLD and CKD in the Nephrology community. Methods and Results: Using a Delphi-based approach, a multidisciplinary panel of 50 international experts from 26 countries reached a consensus on some of the open research questions regarding the link between MAFLD and CKD. Conclusions: This Delphi-based consensus statement provided guidance on the epidemiology, mechanisms, management and treatment of MAFLD and CKD, as well as the relationship between the severity of MAFLD and risk of CKD, which establish a framework for the early prevention and management of these two common and interconnected diseases.
Fil: Sun, Dan Qin. Jiangnan University Medical Center; China. Nantong University; China
Fil: Targher, Giovanni. Azienda Ospedaliera Universitaria Integrata Verona; Italia
Fil: Byrne, Christopher D.. University of Southampton; Reino Unido
Fil: Wheeler, David C.. University College London; Estados Unidos
Fil: Wong, Vincent Wai Sun. Chinese University of Hong Kong; China
Fil: Fan, Jian Gao. Shanghai Jiao Tong University; China
Fil: Tilg, Herbert. Medical University Innsbruck; Austria
Fil: Yuan, Wei Jie. Shanghai Jiao Tong University; China
Fil: Wanner, Christoph. Würzburg University Clinic; Alemania
Fil: Gao, Xin. Fudan University; China
Fil: Long, Michelle T.. Boston University School of Medicine; Estados Unidos
Fil: Kanbay, Mehmet. Koc University School of Medicine; Turquía
Fil: Nguyen, Mindie H.. Stanford University Medical Center; Estados Unidos
Fil: Navaneethan, Sankar D.. Baylor College of Medicine; Estados Unidos
Fil: Yilmaz, Yusuf. Marmara University; Turquía. Recep Tayyip Erdoğan University; Turquía
Fil: Huang, Yuli. Southern Medical University; China
Fil: Gani, Rino A.. Universitas Indonesia; Indonesia
Fil: Marzuillo, Pierluigi. Università della Campania “Luigi Vanvitelli”; Italia
Fil: Boursier, Jérôme. Angers University; Francia
Fil: Zhang, Huijie. Southern Medical University; China
Fil: Jung, Chan Young. Yonsei University; Corea del Sur
Fil: Chai, Jin. Army Medical University; China
Fil: Valenti, Luca. Università degli Studi di Milano; Italia
Fil: Papatheodoridis, George. Kapodistrian University of Athens; Grecia
Fil: Sookoian, Silvia Cristina. Centro de Investigacion Traslacional En Salud (cenitres) ; Facultad de Cs. de la Salud ; Universidad Maimonides; . Universidad Abierta Interamericana; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Chunsun, Dai. Nanjing Medical University; China
Fil: Eslam, Mohammed. University of Sydney; Australia
Fil: Wei, Lai. Tsinghua University; China
Fil: George, Jacob. University of Sydney; Australia
Fil: Zheng, Ming Hua. Wenzhou Medical University; China
description Background: With the rising global prevalence of fatty liver disease related to metabolic dysfunction, the association of this common liver condition with chronic kidney disease (CKD) has become increasingly evident. In 2020, the more inclusive term metabolic dysfunction-associated fatty liver disease (MAFLD) was proposed to replace the term non-alcoholic fatty liver disease (NAFLD). The observed association between MAFLD and CKD and our understanding that CKD can be a consequence of underlying metabolic dysfunction support the notion that individuals with MAFLD are at higher risk of having and developing CKD compared with those without MAFLD. However, to date, there is no appropriate guidance on CKD in individuals with MAFLD. Furthermore, there has been little attention paid to the link between MAFLD and CKD in the Nephrology community. Methods and Results: Using a Delphi-based approach, a multidisciplinary panel of 50 international experts from 26 countries reached a consensus on some of the open research questions regarding the link between MAFLD and CKD. Conclusions: This Delphi-based consensus statement provided guidance on the epidemiology, mechanisms, management and treatment of MAFLD and CKD, as well as the relationship between the severity of MAFLD and risk of CKD, which establish a framework for the early prevention and management of these two common and interconnected diseases.
publishDate 2023
dc.date.none.fl_str_mv 2023-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/221030
Sun, Dan Qin; Targher, Giovanni; Byrne, Christopher D.; Wheeler, David C.; Wong, Vincent Wai Sun; et al.; An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease; AME Publishing Company; Hepatobiliary Surgery and Nutrition; 12; 3; 6-2023; 386-403
2304-3881
2304-389X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/221030
identifier_str_mv Sun, Dan Qin; Targher, Giovanni; Byrne, Christopher D.; Wheeler, David C.; Wong, Vincent Wai Sun; et al.; An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease; AME Publishing Company; Hepatobiliary Surgery and Nutrition; 12; 3; 6-2023; 386-403
2304-3881
2304-389X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://hbsn.amegroups.com/article/view/110403/html
info:eu-repo/semantics/altIdentifier/doi/10.21037/hbsn-22-421
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv AME Publishing Company
publisher.none.fl_str_mv AME Publishing Company
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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