Normal and abnormal female sexual differentiation

Autores
di Clemente, Nathalie; Gonzalès, Jacques; Rey, Rodolfo Alberto
Año de publicación
2009
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
At fertilization, genetic sex determines the orientation of sex differentiation. The genital and urinary systems are closely related embryologically and their common origin is the mesoderm. Primordial germ cells migrate through extra-embryonic tissues into the primitive gonad. Differentiation of the gonads precedes the differentiation of the internal tract and then the differentiation of the external genitalia. Although no gene for female orientation has been identified, genes involved in the different steps of genital tract development in females have been discovered. Some are also implicated in sexual differentiation defects in women, shedding light on the mechanisms that underlie congenital genitourinary malformations. To date, many questions remain unanswered.
Fil: di Clemente, Nathalie. Inserm; Francia
Fil: Gonzalès, Jacques. Université Paris Sud; Francia
Fil: Rey, Rodolfo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones Endocrinológicas "Dr. César Bergada". Gobierno de la Ciudad de Buenos Aires. Centro de Investigaciones Endocrinológicas "Dr. César Bergada". Fundación de Endocrinología Infantil. Centro de Investigaciones Endocrinológicas "Dr. César Bergada"; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; Argentina
Materia
AMH
FALLOPIAN TUBES
GENES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/254233
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Normal and abnormal female sexual differentiationdi Clemente, NathalieGonzalès, JacquesRey, Rodolfo AlbertoAMHFALLOPIAN TUBESGENEShttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3At fertilization, genetic sex determines the orientation of sex differentiation. The genital and urinary systems are closely related embryologically and their common origin is the mesoderm. Primordial germ cells migrate through extra-embryonic tissues into the primitive gonad. Differentiation of the gonads precedes the differentiation of the internal tract and then the differentiation of the external genitalia. Although no gene for female orientation has been identified, genes involved in the different steps of genital tract development in females have been discovered. Some are also implicated in sexual differentiation defects in women, shedding light on the mechanisms that underlie congenital genitourinary malformations. To date, many questions remain unanswered.Fil: di Clemente, Nathalie. Inserm; FranciaFil: Gonzalès, Jacques. Université Paris Sud; FranciaFil: Rey, Rodolfo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones Endocrinológicas "Dr. César Bergada". Gobierno de la Ciudad de Buenos Aires. Centro de Investigaciones Endocrinológicas "Dr. César Bergada". Fundación de Endocrinología Infantil. Centro de Investigaciones Endocrinológicas "Dr. César Bergada"; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; ArgentinaTaylor & Francis2009-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/254233di Clemente, Nathalie; Gonzalès, Jacques; Rey, Rodolfo Alberto; Normal and abnormal female sexual differentiation; Taylor & Francis; Expert Review of Obstetrics & Gynecology; 4; 4; 12-2009; 415-4271747-41081747-4116CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/full/10.1586/eog.09.22info:eu-repo/semantics/altIdentifier/doi/10.1586/EOG.09.22info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:01:15Zoai:ri.conicet.gov.ar:11336/254233instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:01:16.198CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Normal and abnormal female sexual differentiation
title Normal and abnormal female sexual differentiation
spellingShingle Normal and abnormal female sexual differentiation
di Clemente, Nathalie
AMH
FALLOPIAN TUBES
GENES
title_short Normal and abnormal female sexual differentiation
title_full Normal and abnormal female sexual differentiation
title_fullStr Normal and abnormal female sexual differentiation
title_full_unstemmed Normal and abnormal female sexual differentiation
title_sort Normal and abnormal female sexual differentiation
dc.creator.none.fl_str_mv di Clemente, Nathalie
Gonzalès, Jacques
Rey, Rodolfo Alberto
author di Clemente, Nathalie
author_facet di Clemente, Nathalie
Gonzalès, Jacques
Rey, Rodolfo Alberto
author_role author
author2 Gonzalès, Jacques
Rey, Rodolfo Alberto
author2_role author
author
dc.subject.none.fl_str_mv AMH
FALLOPIAN TUBES
GENES
topic AMH
FALLOPIAN TUBES
GENES
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv At fertilization, genetic sex determines the orientation of sex differentiation. The genital and urinary systems are closely related embryologically and their common origin is the mesoderm. Primordial germ cells migrate through extra-embryonic tissues into the primitive gonad. Differentiation of the gonads precedes the differentiation of the internal tract and then the differentiation of the external genitalia. Although no gene for female orientation has been identified, genes involved in the different steps of genital tract development in females have been discovered. Some are also implicated in sexual differentiation defects in women, shedding light on the mechanisms that underlie congenital genitourinary malformations. To date, many questions remain unanswered.
Fil: di Clemente, Nathalie. Inserm; Francia
Fil: Gonzalès, Jacques. Université Paris Sud; Francia
Fil: Rey, Rodolfo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones Endocrinológicas "Dr. César Bergada". Gobierno de la Ciudad de Buenos Aires. Centro de Investigaciones Endocrinológicas "Dr. César Bergada". Fundación de Endocrinología Infantil. Centro de Investigaciones Endocrinológicas "Dr. César Bergada"; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; Argentina
description At fertilization, genetic sex determines the orientation of sex differentiation. The genital and urinary systems are closely related embryologically and their common origin is the mesoderm. Primordial germ cells migrate through extra-embryonic tissues into the primitive gonad. Differentiation of the gonads precedes the differentiation of the internal tract and then the differentiation of the external genitalia. Although no gene for female orientation has been identified, genes involved in the different steps of genital tract development in females have been discovered. Some are also implicated in sexual differentiation defects in women, shedding light on the mechanisms that underlie congenital genitourinary malformations. To date, many questions remain unanswered.
publishDate 2009
dc.date.none.fl_str_mv 2009-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/254233
di Clemente, Nathalie; Gonzalès, Jacques; Rey, Rodolfo Alberto; Normal and abnormal female sexual differentiation; Taylor & Francis; Expert Review of Obstetrics & Gynecology; 4; 4; 12-2009; 415-427
1747-4108
1747-4116
CONICET Digital
CONICET
url http://hdl.handle.net/11336/254233
identifier_str_mv di Clemente, Nathalie; Gonzalès, Jacques; Rey, Rodolfo Alberto; Normal and abnormal female sexual differentiation; Taylor & Francis; Expert Review of Obstetrics & Gynecology; 4; 4; 12-2009; 415-427
1747-4108
1747-4116
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/full/10.1586/eog.09.22
info:eu-repo/semantics/altIdentifier/doi/10.1586/EOG.09.22
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Taylor & Francis
publisher.none.fl_str_mv Taylor & Francis
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842979936828129280
score 12.48226

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