Effect of aneurysm and ICA morphology on hemodynamics before and after flow diverter treatment

Autores
Larrabide, Ignacio; Geers, Arjan J.; Morales, Hernán G.; Aguilar, Martha L.; Rufenacht, Daniel A.
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: Flow diverter (FD) treatment aims to slow down blood flow inside the aneurysm and increase the average time that blood resides in the aneurysm. Objective: To investigate the relationship between vessel and aneurysm morphology and their influence on the way in which braided FDs change intra-aneurysmal hemodynamics. Materials and methods: Twenty-three patient-specific intracranial aneurysm models at the supraclinoid segment of the internal carotid artery were studied. Vessel and aneurysm morphology was quantified and blood flow was modeled with computational fluid dynamics simulations. The relation between morphologic variables and the hemodynamic variables, WSS (wall shear stress) and totime (ratio between the aneurysm volume and inflow at the aneurysm neck), was assessed statistically. Results: Intra-aneurysmal flow was less dependent on the vessel than on aneurysm morphology. In summary, after treatment with a FD, a greater aneurysm flow reduction and redirection to the vessel main stream should be expected for (a) aneurysms located further away from the curvature peak, (b) aneurysms on the inner side of the bend, (c) aneurysms with no proximal stenosis, and (d) larger aneurysms.
Fil: Larrabide, Ignacio. Universitat Pompeu Fabra; España. Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine; España. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Exactas. Grupo de Plasmas Densos Magnetizados. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Grupo de Plasmas Densos Magnetizados; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Geers, Arjan J.. Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine; España. Universitat Pompeu Fabra; España
Fil: Morales, Hernán G.. Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine; España. Universitat Pompeu Fabra; España
Fil: Aguilar, Martha L.. Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine; España. Universitat Pompeu Fabra; España
Fil: Rufenacht, Daniel A.. Hirslanden Clinic; Suiza
Materia
Intracranial Aneurysms
Computational Fluid Dynamics
Morphology
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/33319
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Effect of aneurysm and ICA morphology on hemodynamics before and after flow diverter treatmentLarrabide, IgnacioGeers, Arjan J.Morales, Hernán G.Aguilar, Martha L.Rufenacht, Daniel A.Intracranial AneurysmsComputational Fluid DynamicsMorphologyhttps://purl.org/becyt/ford/1.2https://purl.org/becyt/ford/1Background: Flow diverter (FD) treatment aims to slow down blood flow inside the aneurysm and increase the average time that blood resides in the aneurysm. Objective: To investigate the relationship between vessel and aneurysm morphology and their influence on the way in which braided FDs change intra-aneurysmal hemodynamics. Materials and methods: Twenty-three patient-specific intracranial aneurysm models at the supraclinoid segment of the internal carotid artery were studied. Vessel and aneurysm morphology was quantified and blood flow was modeled with computational fluid dynamics simulations. The relation between morphologic variables and the hemodynamic variables, WSS (wall shear stress) and totime (ratio between the aneurysm volume and inflow at the aneurysm neck), was assessed statistically. Results: Intra-aneurysmal flow was less dependent on the vessel than on aneurysm morphology. In summary, after treatment with a FD, a greater aneurysm flow reduction and redirection to the vessel main stream should be expected for (a) aneurysms located further away from the curvature peak, (b) aneurysms on the inner side of the bend, (c) aneurysms with no proximal stenosis, and (d) larger aneurysms.Fil: Larrabide, Ignacio. Universitat Pompeu Fabra; España. Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine; España. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Exactas. Grupo de Plasmas Densos Magnetizados. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Grupo de Plasmas Densos Magnetizados; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Geers, Arjan J.. Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine; España. Universitat Pompeu Fabra; EspañaFil: Morales, Hernán G.. Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine; España. Universitat Pompeu Fabra; EspañaFil: Aguilar, Martha L.. Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine; España. Universitat Pompeu Fabra; EspañaFil: Rufenacht, Daniel A.. Hirslanden Clinic; SuizaSociety of NeuroInterventional Surgery2014info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/33319Rufenacht, Daniel A.; Aguilar, Martha L.; Geers, Arjan J.; Larrabide, Ignacio; Morales, Hernán G.; Effect of aneurysm and ICA morphology on hemodynamics before and after flow diverter treatment; Society of NeuroInterventional Surgery; Journal of NeuroInterventional Surgery; 7; 4; 2014; 272-2801759-8478CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1136/neurintsurg-2014-011171info:eu-repo/semantics/altIdentifier/url/http://jnis.bmj.com/content/7/4/272info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:53:51Zoai:ri.conicet.gov.ar:11336/33319instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:53:51.531CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Effect of aneurysm and ICA morphology on hemodynamics before and after flow diverter treatment
title Effect of aneurysm and ICA morphology on hemodynamics before and after flow diverter treatment
spellingShingle Effect of aneurysm and ICA morphology on hemodynamics before and after flow diverter treatment
Larrabide, Ignacio
Intracranial Aneurysms
Computational Fluid Dynamics
Morphology
title_short Effect of aneurysm and ICA morphology on hemodynamics before and after flow diverter treatment
title_full Effect of aneurysm and ICA morphology on hemodynamics before and after flow diverter treatment
title_fullStr Effect of aneurysm and ICA morphology on hemodynamics before and after flow diverter treatment
title_full_unstemmed Effect of aneurysm and ICA morphology on hemodynamics before and after flow diverter treatment
title_sort Effect of aneurysm and ICA morphology on hemodynamics before and after flow diverter treatment
dc.creator.none.fl_str_mv Larrabide, Ignacio
Geers, Arjan J.
Morales, Hernán G.
Aguilar, Martha L.
Rufenacht, Daniel A.
author Larrabide, Ignacio
author_facet Larrabide, Ignacio
Geers, Arjan J.
Morales, Hernán G.
Aguilar, Martha L.
Rufenacht, Daniel A.
author_role author
author2 Geers, Arjan J.
Morales, Hernán G.
Aguilar, Martha L.
Rufenacht, Daniel A.
author2_role author
author
author
author
dc.subject.none.fl_str_mv Intracranial Aneurysms
Computational Fluid Dynamics
Morphology
topic Intracranial Aneurysms
Computational Fluid Dynamics
Morphology
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.2
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Background: Flow diverter (FD) treatment aims to slow down blood flow inside the aneurysm and increase the average time that blood resides in the aneurysm. Objective: To investigate the relationship between vessel and aneurysm morphology and their influence on the way in which braided FDs change intra-aneurysmal hemodynamics. Materials and methods: Twenty-three patient-specific intracranial aneurysm models at the supraclinoid segment of the internal carotid artery were studied. Vessel and aneurysm morphology was quantified and blood flow was modeled with computational fluid dynamics simulations. The relation between morphologic variables and the hemodynamic variables, WSS (wall shear stress) and totime (ratio between the aneurysm volume and inflow at the aneurysm neck), was assessed statistically. Results: Intra-aneurysmal flow was less dependent on the vessel than on aneurysm morphology. In summary, after treatment with a FD, a greater aneurysm flow reduction and redirection to the vessel main stream should be expected for (a) aneurysms located further away from the curvature peak, (b) aneurysms on the inner side of the bend, (c) aneurysms with no proximal stenosis, and (d) larger aneurysms.
Fil: Larrabide, Ignacio. Universitat Pompeu Fabra; España. Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine; España. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Exactas. Grupo de Plasmas Densos Magnetizados. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Grupo de Plasmas Densos Magnetizados; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Geers, Arjan J.. Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine; España. Universitat Pompeu Fabra; España
Fil: Morales, Hernán G.. Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine; España. Universitat Pompeu Fabra; España
Fil: Aguilar, Martha L.. Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine; España. Universitat Pompeu Fabra; España
Fil: Rufenacht, Daniel A.. Hirslanden Clinic; Suiza
description Background: Flow diverter (FD) treatment aims to slow down blood flow inside the aneurysm and increase the average time that blood resides in the aneurysm. Objective: To investigate the relationship between vessel and aneurysm morphology and their influence on the way in which braided FDs change intra-aneurysmal hemodynamics. Materials and methods: Twenty-three patient-specific intracranial aneurysm models at the supraclinoid segment of the internal carotid artery were studied. Vessel and aneurysm morphology was quantified and blood flow was modeled with computational fluid dynamics simulations. The relation between morphologic variables and the hemodynamic variables, WSS (wall shear stress) and totime (ratio between the aneurysm volume and inflow at the aneurysm neck), was assessed statistically. Results: Intra-aneurysmal flow was less dependent on the vessel than on aneurysm morphology. In summary, after treatment with a FD, a greater aneurysm flow reduction and redirection to the vessel main stream should be expected for (a) aneurysms located further away from the curvature peak, (b) aneurysms on the inner side of the bend, (c) aneurysms with no proximal stenosis, and (d) larger aneurysms.
publishDate 2014
dc.date.none.fl_str_mv 2014
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/33319
Rufenacht, Daniel A.; Aguilar, Martha L.; Geers, Arjan J.; Larrabide, Ignacio; Morales, Hernán G.; Effect of aneurysm and ICA morphology on hemodynamics before and after flow diverter treatment; Society of NeuroInterventional Surgery; Journal of NeuroInterventional Surgery; 7; 4; 2014; 272-280
1759-8478
CONICET Digital
CONICET
url http://hdl.handle.net/11336/33319
identifier_str_mv Rufenacht, Daniel A.; Aguilar, Martha L.; Geers, Arjan J.; Larrabide, Ignacio; Morales, Hernán G.; Effect of aneurysm and ICA morphology on hemodynamics before and after flow diverter treatment; Society of NeuroInterventional Surgery; Journal of NeuroInterventional Surgery; 7; 4; 2014; 272-280
1759-8478
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1136/neurintsurg-2014-011171
info:eu-repo/semantics/altIdentifier/url/http://jnis.bmj.com/content/7/4/272
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Society of NeuroInterventional Surgery
publisher.none.fl_str_mv Society of NeuroInterventional Surgery
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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