Effectiveness of an mHealth intervention to increase adherence to triage of HPV DNA positive women who have performed self-collection (the ATICA study): A hybrid type I cluster ran...

Autores
Arrossi, Silvina; Paolino, Melisa Delia; Sánchez Antelo, Victoria Inés María; Thouyaret, Laura; Kohler, Racquel; Cuberli, Milca; Flores, Liliana; Serra, Verónica; Viswanath, Kasisomayajula; Orellana, Liliana
Año de publicación
2022
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: Human Papillomavirus (HPV) self-collection offered by community health workers (CHWs) during home visits has been hampered by low levels of triage Pap among HPV-positive women. We investigated effectiveness of a mHealth intervention to increase adherence to triage Pap. Methods: We conducted a hybrid type I cluster randomised effectiveness-implementation trial in Jujuy, Argentina. CHWs (clusters) were eligible if actively offering HPV self-collection and served at least 26 women aged 30 years and over. Women were eligible if they conducted self-collection and provided a mobile phone number. 260 CHWs were randomly allocated (3:2 ratio) to a multi-component intervention (Up to four SMS messages sent to HPV-positive women, and one SMS message to CHWs to prompt a visit of women with no triage Pap 60 days after a positive-test), or control group (Usual care: Women instructed to attend their health centre 30 days after HPV self-collection to pick-up results). The primary effectiveness outcome was percentage of HPV-positive women with triage 120 days after the HPV-test result. We evaluated implementation of the intervention using the RE-AIM framework. Findings: 221 CHWs (132 intervention, 89 control group) contacted 5389 women; and 5351 agreed to participate (3241 intervention, 2110 control group). In total 314/445 (70·5%) HPV-positive women of the intervention group had triage at 120 days after the HPV result, compared to 163/292 (55·1%) in the control group: 15·5% point improvement; 95%CI: 6·8–24·1; relative risk: 1·28; 95%CI: 1·11–1·48. 97·2% of women accepted the intervention and 86·9% of CHWs agreed to its adoption. Interpretation: The multicomponent mHealth intervention was effective in increasing the percentage of HPV-positive women who had triage Pap, allowing for many more women at risk of cervical cancer to receive timely follow-up. Funding: National Cancer Institute of the National Institutes of Health (USA) under Award Number R01CA218306.
Fil: Arrossi, Silvina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Centro de Estudio de Estado y Sociedad; Argentina
Fil: Paolino, Melisa Delia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Centro de Estudio de Estado y Sociedad; Argentina
Fil: Sánchez Antelo, Victoria Inés María. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Centro de Estudio de Estado y Sociedad; Argentina
Fil: Thouyaret, Laura. Ministerio de Salud de la Nación; Argentina
Fil: Kohler, Racquel. State University of New Jersey; Estados Unidos
Fil: Cuberli, Milca. Instituto Nacional del Cáncer; Argentina
Fil: Flores, Liliana. Gobierno de la Provincia de Jujuy. Ministerio de Salud; Argentina
Fil: Serra, Verónica. Gobierno de la Provincia de Jujuy. Ministerio de Salud; Argentina
Fil: Viswanath, Kasisomayajula. Harvard University. Harvard School of Public Health; Estados Unidos
Fil: Orellana, Liliana. Deakin University; Australia
Materia
ARGENTINA
CERVICAL CANCER
COMMUNITY HEALTH WORKERS
HPV SELF-COLLECTION
IMPLEMENTATION SCIENCE
MHEALTH
PREVENTION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/222102
Acceder
id CONICETDig_0cad02ffb5437641f33d9859d623d407
oai_identifier_str oai:ri.conicet.gov.ar:11336/222102
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Effectiveness of an mHealth intervention to increase adherence to triage of HPV DNA positive women who have performed self-collection (the ATICA study): A hybrid type I cluster randomised effectiveness-implementation trialArrossi, SilvinaPaolino, Melisa DeliaSánchez Antelo, Victoria Inés MaríaThouyaret, LauraKohler, RacquelCuberli, MilcaFlores, LilianaSerra, VerónicaViswanath, KasisomayajulaOrellana, LilianaARGENTINACERVICAL CANCERCOMMUNITY HEALTH WORKERSHPV SELF-COLLECTIONIMPLEMENTATION SCIENCEMHEALTHPREVENTIONhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Background: Human Papillomavirus (HPV) self-collection offered by community health workers (CHWs) during home visits has been hampered by low levels of triage Pap among HPV-positive women. We investigated effectiveness of a mHealth intervention to increase adherence to triage Pap. Methods: We conducted a hybrid type I cluster randomised effectiveness-implementation trial in Jujuy, Argentina. CHWs (clusters) were eligible if actively offering HPV self-collection and served at least 26 women aged 30 years and over. Women were eligible if they conducted self-collection and provided a mobile phone number. 260 CHWs were randomly allocated (3:2 ratio) to a multi-component intervention (Up to four SMS messages sent to HPV-positive women, and one SMS message to CHWs to prompt a visit of women with no triage Pap 60 days after a positive-test), or control group (Usual care: Women instructed to attend their health centre 30 days after HPV self-collection to pick-up results). The primary effectiveness outcome was percentage of HPV-positive women with triage 120 days after the HPV-test result. We evaluated implementation of the intervention using the RE-AIM framework. Findings: 221 CHWs (132 intervention, 89 control group) contacted 5389 women; and 5351 agreed to participate (3241 intervention, 2110 control group). In total 314/445 (70·5%) HPV-positive women of the intervention group had triage at 120 days after the HPV result, compared to 163/292 (55·1%) in the control group: 15·5% point improvement; 95%CI: 6·8–24·1; relative risk: 1·28; 95%CI: 1·11–1·48. 97·2% of women accepted the intervention and 86·9% of CHWs agreed to its adoption. Interpretation: The multicomponent mHealth intervention was effective in increasing the percentage of HPV-positive women who had triage Pap, allowing for many more women at risk of cervical cancer to receive timely follow-up. Funding: National Cancer Institute of the National Institutes of Health (USA) under Award Number R01CA218306.Fil: Arrossi, Silvina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Centro de Estudio de Estado y Sociedad; ArgentinaFil: Paolino, Melisa Delia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Centro de Estudio de Estado y Sociedad; ArgentinaFil: Sánchez Antelo, Victoria Inés María. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Centro de Estudio de Estado y Sociedad; ArgentinaFil: Thouyaret, Laura. Ministerio de Salud de la Nación; ArgentinaFil: Kohler, Racquel. State University of New Jersey; Estados UnidosFil: Cuberli, Milca. Instituto Nacional del Cáncer; ArgentinaFil: Flores, Liliana. Gobierno de la Provincia de Jujuy. Ministerio de Salud; ArgentinaFil: Serra, Verónica. Gobierno de la Provincia de Jujuy. Ministerio de Salud; ArgentinaFil: Viswanath, Kasisomayajula. Harvard University. Harvard School of Public Health; Estados UnidosFil: Orellana, Liliana. Deakin University; AustraliaElsevier2022-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/222102Arrossi, Silvina; Paolino, Melisa Delia; Sánchez Antelo, Victoria Inés María; Thouyaret, Laura; Kohler, Racquel; et al.; Effectiveness of an mHealth intervention to increase adherence to triage of HPV DNA positive women who have performed self-collection (the ATICA study): A hybrid type I cluster randomised effectiveness-implementation trial; Elsevier; The Lancet Regional Health - Americas; 9; 100199; 5-2022; 1-182667-193XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.lana.2022.100199info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S2667193X22000163info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:10:12Zoai:ri.conicet.gov.ar:11336/222102instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:10:12.828CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Effectiveness of an mHealth intervention to increase adherence to triage of HPV DNA positive women who have performed self-collection (the ATICA study): A hybrid type I cluster randomised effectiveness-implementation trial
title Effectiveness of an mHealth intervention to increase adherence to triage of HPV DNA positive women who have performed self-collection (the ATICA study): A hybrid type I cluster randomised effectiveness-implementation trial
spellingShingle Effectiveness of an mHealth intervention to increase adherence to triage of HPV DNA positive women who have performed self-collection (the ATICA study): A hybrid type I cluster randomised effectiveness-implementation trial
Arrossi, Silvina
ARGENTINA
CERVICAL CANCER
COMMUNITY HEALTH WORKERS
HPV SELF-COLLECTION
IMPLEMENTATION SCIENCE
MHEALTH
PREVENTION
title_short Effectiveness of an mHealth intervention to increase adherence to triage of HPV DNA positive women who have performed self-collection (the ATICA study): A hybrid type I cluster randomised effectiveness-implementation trial
title_full Effectiveness of an mHealth intervention to increase adherence to triage of HPV DNA positive women who have performed self-collection (the ATICA study): A hybrid type I cluster randomised effectiveness-implementation trial
title_fullStr Effectiveness of an mHealth intervention to increase adherence to triage of HPV DNA positive women who have performed self-collection (the ATICA study): A hybrid type I cluster randomised effectiveness-implementation trial
title_full_unstemmed Effectiveness of an mHealth intervention to increase adherence to triage of HPV DNA positive women who have performed self-collection (the ATICA study): A hybrid type I cluster randomised effectiveness-implementation trial
title_sort Effectiveness of an mHealth intervention to increase adherence to triage of HPV DNA positive women who have performed self-collection (the ATICA study): A hybrid type I cluster randomised effectiveness-implementation trial
dc.creator.none.fl_str_mv Arrossi, Silvina
Paolino, Melisa Delia
Sánchez Antelo, Victoria Inés María
Thouyaret, Laura
Kohler, Racquel
Cuberli, Milca
Flores, Liliana
Serra, Verónica
Viswanath, Kasisomayajula
Orellana, Liliana
author Arrossi, Silvina
author_facet Arrossi, Silvina
Paolino, Melisa Delia
Sánchez Antelo, Victoria Inés María
Thouyaret, Laura
Kohler, Racquel
Cuberli, Milca
Flores, Liliana
Serra, Verónica
Viswanath, Kasisomayajula
Orellana, Liliana
author_role author
author2 Paolino, Melisa Delia
Sánchez Antelo, Victoria Inés María
Thouyaret, Laura
Kohler, Racquel
Cuberli, Milca
Flores, Liliana
Serra, Verónica
Viswanath, Kasisomayajula
Orellana, Liliana
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv ARGENTINA
CERVICAL CANCER
COMMUNITY HEALTH WORKERS
HPV SELF-COLLECTION
IMPLEMENTATION SCIENCE
MHEALTH
PREVENTION
topic ARGENTINA
CERVICAL CANCER
COMMUNITY HEALTH WORKERS
HPV SELF-COLLECTION
IMPLEMENTATION SCIENCE
MHEALTH
PREVENTION
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Background: Human Papillomavirus (HPV) self-collection offered by community health workers (CHWs) during home visits has been hampered by low levels of triage Pap among HPV-positive women. We investigated effectiveness of a mHealth intervention to increase adherence to triage Pap. Methods: We conducted a hybrid type I cluster randomised effectiveness-implementation trial in Jujuy, Argentina. CHWs (clusters) were eligible if actively offering HPV self-collection and served at least 26 women aged 30 years and over. Women were eligible if they conducted self-collection and provided a mobile phone number. 260 CHWs were randomly allocated (3:2 ratio) to a multi-component intervention (Up to four SMS messages sent to HPV-positive women, and one SMS message to CHWs to prompt a visit of women with no triage Pap 60 days after a positive-test), or control group (Usual care: Women instructed to attend their health centre 30 days after HPV self-collection to pick-up results). The primary effectiveness outcome was percentage of HPV-positive women with triage 120 days after the HPV-test result. We evaluated implementation of the intervention using the RE-AIM framework. Findings: 221 CHWs (132 intervention, 89 control group) contacted 5389 women; and 5351 agreed to participate (3241 intervention, 2110 control group). In total 314/445 (70·5%) HPV-positive women of the intervention group had triage at 120 days after the HPV result, compared to 163/292 (55·1%) in the control group: 15·5% point improvement; 95%CI: 6·8–24·1; relative risk: 1·28; 95%CI: 1·11–1·48. 97·2% of women accepted the intervention and 86·9% of CHWs agreed to its adoption. Interpretation: The multicomponent mHealth intervention was effective in increasing the percentage of HPV-positive women who had triage Pap, allowing for many more women at risk of cervical cancer to receive timely follow-up. Funding: National Cancer Institute of the National Institutes of Health (USA) under Award Number R01CA218306.
Fil: Arrossi, Silvina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Centro de Estudio de Estado y Sociedad; Argentina
Fil: Paolino, Melisa Delia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Centro de Estudio de Estado y Sociedad; Argentina
Fil: Sánchez Antelo, Victoria Inés María. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Centro de Estudio de Estado y Sociedad; Argentina
Fil: Thouyaret, Laura. Ministerio de Salud de la Nación; Argentina
Fil: Kohler, Racquel. State University of New Jersey; Estados Unidos
Fil: Cuberli, Milca. Instituto Nacional del Cáncer; Argentina
Fil: Flores, Liliana. Gobierno de la Provincia de Jujuy. Ministerio de Salud; Argentina
Fil: Serra, Verónica. Gobierno de la Provincia de Jujuy. Ministerio de Salud; Argentina
Fil: Viswanath, Kasisomayajula. Harvard University. Harvard School of Public Health; Estados Unidos
Fil: Orellana, Liliana. Deakin University; Australia
description Background: Human Papillomavirus (HPV) self-collection offered by community health workers (CHWs) during home visits has been hampered by low levels of triage Pap among HPV-positive women. We investigated effectiveness of a mHealth intervention to increase adherence to triage Pap. Methods: We conducted a hybrid type I cluster randomised effectiveness-implementation trial in Jujuy, Argentina. CHWs (clusters) were eligible if actively offering HPV self-collection and served at least 26 women aged 30 years and over. Women were eligible if they conducted self-collection and provided a mobile phone number. 260 CHWs were randomly allocated (3:2 ratio) to a multi-component intervention (Up to four SMS messages sent to HPV-positive women, and one SMS message to CHWs to prompt a visit of women with no triage Pap 60 days after a positive-test), or control group (Usual care: Women instructed to attend their health centre 30 days after HPV self-collection to pick-up results). The primary effectiveness outcome was percentage of HPV-positive women with triage 120 days after the HPV-test result. We evaluated implementation of the intervention using the RE-AIM framework. Findings: 221 CHWs (132 intervention, 89 control group) contacted 5389 women; and 5351 agreed to participate (3241 intervention, 2110 control group). In total 314/445 (70·5%) HPV-positive women of the intervention group had triage at 120 days after the HPV result, compared to 163/292 (55·1%) in the control group: 15·5% point improvement; 95%CI: 6·8–24·1; relative risk: 1·28; 95%CI: 1·11–1·48. 97·2% of women accepted the intervention and 86·9% of CHWs agreed to its adoption. Interpretation: The multicomponent mHealth intervention was effective in increasing the percentage of HPV-positive women who had triage Pap, allowing for many more women at risk of cervical cancer to receive timely follow-up. Funding: National Cancer Institute of the National Institutes of Health (USA) under Award Number R01CA218306.
publishDate 2022
dc.date.none.fl_str_mv 2022-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/222102
Arrossi, Silvina; Paolino, Melisa Delia; Sánchez Antelo, Victoria Inés María; Thouyaret, Laura; Kohler, Racquel; et al.; Effectiveness of an mHealth intervention to increase adherence to triage of HPV DNA positive women who have performed self-collection (the ATICA study): A hybrid type I cluster randomised effectiveness-implementation trial; Elsevier; The Lancet Regional Health - Americas; 9; 100199; 5-2022; 1-18
2667-193X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/222102
identifier_str_mv Arrossi, Silvina; Paolino, Melisa Delia; Sánchez Antelo, Victoria Inés María; Thouyaret, Laura; Kohler, Racquel; et al.; Effectiveness of an mHealth intervention to increase adherence to triage of HPV DNA positive women who have performed self-collection (the ATICA study): A hybrid type I cluster randomised effectiveness-implementation trial; Elsevier; The Lancet Regional Health - Americas; 9; 100199; 5-2022; 1-18
2667-193X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.lana.2022.100199
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S2667193X22000163
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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