Total reflection X-ray fluorescence as a fast multielemental technique for human placenta sample analysis

Autores
Marguí, E.; Ricketts, Phylicia; Fletcher, H.; Karydas, A.G.; Migliori, A.; Leani, Juan Jose; Hidalgo, M.; Queralt, Ignacio; Voutchkov, M.
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In the present contribution, benchtop total reflection X-ray fluorescence spectrometry (TXRF) has been evaluated as a cost-effective multielemental analytical technique for human placenta analysis. An easy and rapid sample preparation consisting of suspending 50 mg of sample in 1 mL of a Triton 1% solution in deionized water showed to be the most suitable for this kind of samples. However, for comparison purposes, an acidic microwave acidic digestion procedure was also applied. For both sample treatment methodologies, limits of detection for most elements were in the low mg/kg level. Accurate and precise results were obtained using internal standardization as quantification approach and applying a correction factor to compensate for absorption effects. The correction factor was based on the proportional ratio between the slurry preparation results and those obtained for the analysis of a set of human placenta samples analysed by microwave acidic digestion and ICP-AES analysis. As a study case, the developed TXRF methodology was applied for multielemental analysis (K, Ca, Fe, Cu, Zn, As, Se, Br, Rb and Sr) of several healthy women's placenta samples from two regions in Jamaica.
Fil: Marguí, E.. Universidad de Girona; España
Fil: Ricketts, Phylicia. University of the West Indies; Jamaica
Fil: Fletcher, H.. University of the West Indies; Jamaica
Fil: Karydas, A.G.. IAEA Laboratories; Austria. National Center for Scientific Research “Demokritos”; Grecia
Fil: Migliori, A.. IAEA Laboratories; Austria
Fil: Leani, Juan Jose. IAEA Laboratories; Austria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina
Fil: Hidalgo, M.. Universidad de Girona; España
Fil: Queralt, Ignacio. Universidad de Girona; España. Consejo Superior de Investigaciones Científicas; España
Fil: Voutchkov, M.. University of the West Indies; Jamaica
Materia
MULTIELEMENTAL ANALYSIS
PLACENTA
SLURRY
SUSPENSION
SYNCHROTRON
TXRF
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/97346
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/97346
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Total reflection X-ray fluorescence as a fast multielemental technique for human placenta sample analysisMarguí, E.Ricketts, PhyliciaFletcher, H.Karydas, A.G.Migliori, A.Leani, Juan JoseHidalgo, M.Queralt, IgnacioVoutchkov, M.MULTIELEMENTAL ANALYSISPLACENTASLURRYSUSPENSIONSYNCHROTRONTXRFhttps://purl.org/becyt/ford/1.3https://purl.org/becyt/ford/1In the present contribution, benchtop total reflection X-ray fluorescence spectrometry (TXRF) has been evaluated as a cost-effective multielemental analytical technique for human placenta analysis. An easy and rapid sample preparation consisting of suspending 50 mg of sample in 1 mL of a Triton 1% solution in deionized water showed to be the most suitable for this kind of samples. However, for comparison purposes, an acidic microwave acidic digestion procedure was also applied. For both sample treatment methodologies, limits of detection for most elements were in the low mg/kg level. Accurate and precise results were obtained using internal standardization as quantification approach and applying a correction factor to compensate for absorption effects. The correction factor was based on the proportional ratio between the slurry preparation results and those obtained for the analysis of a set of human placenta samples analysed by microwave acidic digestion and ICP-AES analysis. As a study case, the developed TXRF methodology was applied for multielemental analysis (K, Ca, Fe, Cu, Zn, As, Se, Br, Rb and Sr) of several healthy women's placenta samples from two regions in Jamaica.Fil: Marguí, E.. Universidad de Girona; EspañaFil: Ricketts, Phylicia. University of the West Indies; JamaicaFil: Fletcher, H.. University of the West Indies; JamaicaFil: Karydas, A.G.. IAEA Laboratories; Austria. National Center for Scientific Research “Demokritos”; GreciaFil: Migliori, A.. IAEA Laboratories; AustriaFil: Leani, Juan Jose. IAEA Laboratories; Austria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; ArgentinaFil: Hidalgo, M.. Universidad de Girona; EspañaFil: Queralt, Ignacio. Universidad de Girona; España. Consejo Superior de Investigaciones Científicas; EspañaFil: Voutchkov, M.. University of the West Indies; JamaicaPergamon-Elsevier Science Ltd2017-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/97346Marguí, E.; Ricketts, Phylicia; Fletcher, H.; Karydas, A.G.; Migliori, A.; et al.; Total reflection X-ray fluorescence as a fast multielemental technique for human placenta sample analysis; Pergamon-Elsevier Science Ltd; Spectrochimica Acta Part B: Atomic Spectroscopy; 130; 4-2017; 53-590584-8547CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0584854716303767info:eu-repo/semantics/altIdentifier/doi/10.1016/j.sab.2017.02.008info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:00:00Zoai:ri.conicet.gov.ar:11336/97346instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:00:00.902CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Total reflection X-ray fluorescence as a fast multielemental technique for human placenta sample analysis
title Total reflection X-ray fluorescence as a fast multielemental technique for human placenta sample analysis
spellingShingle Total reflection X-ray fluorescence as a fast multielemental technique for human placenta sample analysis
Marguí, E.
MULTIELEMENTAL ANALYSIS
PLACENTA
SLURRY
SUSPENSION
SYNCHROTRON
TXRF
title_short Total reflection X-ray fluorescence as a fast multielemental technique for human placenta sample analysis
title_full Total reflection X-ray fluorescence as a fast multielemental technique for human placenta sample analysis
title_fullStr Total reflection X-ray fluorescence as a fast multielemental technique for human placenta sample analysis
title_full_unstemmed Total reflection X-ray fluorescence as a fast multielemental technique for human placenta sample analysis
title_sort Total reflection X-ray fluorescence as a fast multielemental technique for human placenta sample analysis
dc.creator.none.fl_str_mv Marguí, E.
Ricketts, Phylicia
Fletcher, H.
Karydas, A.G.
Migliori, A.
Leani, Juan Jose
Hidalgo, M.
Queralt, Ignacio
Voutchkov, M.
author Marguí, E.
author_facet Marguí, E.
Ricketts, Phylicia
Fletcher, H.
Karydas, A.G.
Migliori, A.
Leani, Juan Jose
Hidalgo, M.
Queralt, Ignacio
Voutchkov, M.
author_role author
author2 Ricketts, Phylicia
Fletcher, H.
Karydas, A.G.
Migliori, A.
Leani, Juan Jose
Hidalgo, M.
Queralt, Ignacio
Voutchkov, M.
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv MULTIELEMENTAL ANALYSIS
PLACENTA
SLURRY
SUSPENSION
SYNCHROTRON
TXRF
topic MULTIELEMENTAL ANALYSIS
PLACENTA
SLURRY
SUSPENSION
SYNCHROTRON
TXRF
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv In the present contribution, benchtop total reflection X-ray fluorescence spectrometry (TXRF) has been evaluated as a cost-effective multielemental analytical technique for human placenta analysis. An easy and rapid sample preparation consisting of suspending 50 mg of sample in 1 mL of a Triton 1% solution in deionized water showed to be the most suitable for this kind of samples. However, for comparison purposes, an acidic microwave acidic digestion procedure was also applied. For both sample treatment methodologies, limits of detection for most elements were in the low mg/kg level. Accurate and precise results were obtained using internal standardization as quantification approach and applying a correction factor to compensate for absorption effects. The correction factor was based on the proportional ratio between the slurry preparation results and those obtained for the analysis of a set of human placenta samples analysed by microwave acidic digestion and ICP-AES analysis. As a study case, the developed TXRF methodology was applied for multielemental analysis (K, Ca, Fe, Cu, Zn, As, Se, Br, Rb and Sr) of several healthy women's placenta samples from two regions in Jamaica.
Fil: Marguí, E.. Universidad de Girona; España
Fil: Ricketts, Phylicia. University of the West Indies; Jamaica
Fil: Fletcher, H.. University of the West Indies; Jamaica
Fil: Karydas, A.G.. IAEA Laboratories; Austria. National Center for Scientific Research “Demokritos”; Grecia
Fil: Migliori, A.. IAEA Laboratories; Austria
Fil: Leani, Juan Jose. IAEA Laboratories; Austria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina
Fil: Hidalgo, M.. Universidad de Girona; España
Fil: Queralt, Ignacio. Universidad de Girona; España. Consejo Superior de Investigaciones Científicas; España
Fil: Voutchkov, M.. University of the West Indies; Jamaica
description In the present contribution, benchtop total reflection X-ray fluorescence spectrometry (TXRF) has been evaluated as a cost-effective multielemental analytical technique for human placenta analysis. An easy and rapid sample preparation consisting of suspending 50 mg of sample in 1 mL of a Triton 1% solution in deionized water showed to be the most suitable for this kind of samples. However, for comparison purposes, an acidic microwave acidic digestion procedure was also applied. For both sample treatment methodologies, limits of detection for most elements were in the low mg/kg level. Accurate and precise results were obtained using internal standardization as quantification approach and applying a correction factor to compensate for absorption effects. The correction factor was based on the proportional ratio between the slurry preparation results and those obtained for the analysis of a set of human placenta samples analysed by microwave acidic digestion and ICP-AES analysis. As a study case, the developed TXRF methodology was applied for multielemental analysis (K, Ca, Fe, Cu, Zn, As, Se, Br, Rb and Sr) of several healthy women's placenta samples from two regions in Jamaica.
publishDate 2017
dc.date.none.fl_str_mv 2017-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/97346
Marguí, E.; Ricketts, Phylicia; Fletcher, H.; Karydas, A.G.; Migliori, A.; et al.; Total reflection X-ray fluorescence as a fast multielemental technique for human placenta sample analysis; Pergamon-Elsevier Science Ltd; Spectrochimica Acta Part B: Atomic Spectroscopy; 130; 4-2017; 53-59
0584-8547
CONICET Digital
CONICET
url http://hdl.handle.net/11336/97346
identifier_str_mv Marguí, E.; Ricketts, Phylicia; Fletcher, H.; Karydas, A.G.; Migliori, A.; et al.; Total reflection X-ray fluorescence as a fast multielemental technique for human placenta sample analysis; Pergamon-Elsevier Science Ltd; Spectrochimica Acta Part B: Atomic Spectroscopy; 130; 4-2017; 53-59
0584-8547
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0584854716303767
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.sab.2017.02.008
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842979852599164928
score 12.48226

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