A chloroplast retrograde signal regulates nuclear alternative splicing

Autores
Petrillo, Ezequiel; Godoy Herz, Micaela Amalia; Fuchs, Armin; Reifer, Dominik; Fuller, John; Yanovsky, Marcelo Javier; Simpson, Craig; Brown, John W; Barta, Andrea; Kalyna, Maria; Kornblihtt, Alberto Rodolfo
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Light is a source of energy and also a regulator of plant physiological adaptations. We show here that light/dark conditions affect alternative splicing of a subset of Arabidopsis genes preferentially encoding proteins involved in RNA processing. The effect requires functional chloroplasts and is also observed in roots when the communication with the photosynthetic tissues is not interrupted, suggesting that a signaling molecule travels through the plant. Using photosynthetic electron transfer inhibitors with different mechanisms of action, we deduce that the reduced pool of plastoquinones initiates a chloroplast retrograde signaling that regulates nuclear alternative splicing and is necessary for proper plant responses to varying light conditions.
Fil: Petrillo, Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
Fil: Godoy Herz, Micaela Amalia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
Fil: Fuchs, Armin. Medical University of Vienna. Max F. Perutz Laboratories; Austria
Fil: Reifer, Dominik. Medical University of Vienna. Max F. Perutz Laboratories; Austria
Fil: Fuller, John. The James Hutton Institute. Cell and Molecular Sciences; Reino Unido
Fil: Yanovsky, Marcelo Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; Argentina. Fundación Instituto Leloir; Argentina
Fil: Simpson, Craig. The James Hutton Institute. Cell and Molecular Sciences; Reino Unido
Fil: Brown, John W. The James Hutton Institute. Cell and Molecular Sciences; Reino Unido
Fil: Barta, Andrea. Medical University of Vienna. Max F. Perutz Laboratories; Austria
Fil: Kalyna, Maria. Medical University of Vienna. Max F. Perutz Laboratories; Austria
Fil: Kornblihtt, Alberto Rodolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
Materia
Splicing Alternativo
Plantas
Cloroplasto
Luz/Oscuridad
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/8917
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/8917
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling A chloroplast retrograde signal regulates nuclear alternative splicingPetrillo, EzequielGodoy Herz, Micaela AmaliaFuchs, ArminReifer, DominikFuller, JohnYanovsky, Marcelo JavierSimpson, CraigBrown, John WBarta, AndreaKalyna, MariaKornblihtt, Alberto RodolfoSplicing AlternativoPlantasCloroplastoLuz/Oscuridadhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Light is a source of energy and also a regulator of plant physiological adaptations. We show here that light/dark conditions affect alternative splicing of a subset of Arabidopsis genes preferentially encoding proteins involved in RNA processing. The effect requires functional chloroplasts and is also observed in roots when the communication with the photosynthetic tissues is not interrupted, suggesting that a signaling molecule travels through the plant. Using photosynthetic electron transfer inhibitors with different mechanisms of action, we deduce that the reduced pool of plastoquinones initiates a chloroplast retrograde signaling that regulates nuclear alternative splicing and is necessary for proper plant responses to varying light conditions.Fil: Petrillo, Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Godoy Herz, Micaela Amalia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Fuchs, Armin. Medical University of Vienna. Max F. Perutz Laboratories; AustriaFil: Reifer, Dominik. Medical University of Vienna. Max F. Perutz Laboratories; AustriaFil: Fuller, John. The James Hutton Institute. Cell and Molecular Sciences; Reino UnidoFil: Yanovsky, Marcelo Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; Argentina. Fundación Instituto Leloir; ArgentinaFil: Simpson, Craig. The James Hutton Institute. Cell and Molecular Sciences; Reino UnidoFil: Brown, John W. The James Hutton Institute. Cell and Molecular Sciences; Reino UnidoFil: Barta, Andrea. Medical University of Vienna. Max F. Perutz Laboratories; AustriaFil: Kalyna, Maria. Medical University of Vienna. Max F. Perutz Laboratories; AustriaFil: Kornblihtt, Alberto Rodolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaAmerican Association For The Advancement Of Science2014-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/8917Petrillo, Ezequiel; Godoy Herz, Micaela Amalia; Fuchs, Armin; Reifer, Dominik; Fuller, John; et al.; A chloroplast retrograde signal regulates nuclear alternative splicing; American Association For The Advancement Of Science; Science; 344; 6182; 4-2014; 427-4300036-8075enginfo:eu-repo/semantics/altIdentifier/url/http://science.sciencemag.org/content/344/6182/427info:eu-repo/semantics/altIdentifier/doi/10.1126/science.1250322info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:24:03Zoai:ri.conicet.gov.ar:11336/8917instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:24:03.321CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv A chloroplast retrograde signal regulates nuclear alternative splicing
title A chloroplast retrograde signal regulates nuclear alternative splicing
spellingShingle A chloroplast retrograde signal regulates nuclear alternative splicing
Petrillo, Ezequiel
Splicing Alternativo
Plantas
Cloroplasto
Luz/Oscuridad
title_short A chloroplast retrograde signal regulates nuclear alternative splicing
title_full A chloroplast retrograde signal regulates nuclear alternative splicing
title_fullStr A chloroplast retrograde signal regulates nuclear alternative splicing
title_full_unstemmed A chloroplast retrograde signal regulates nuclear alternative splicing
title_sort A chloroplast retrograde signal regulates nuclear alternative splicing
dc.creator.none.fl_str_mv Petrillo, Ezequiel
Godoy Herz, Micaela Amalia
Fuchs, Armin
Reifer, Dominik
Fuller, John
Yanovsky, Marcelo Javier
Simpson, Craig
Brown, John W
Barta, Andrea
Kalyna, Maria
Kornblihtt, Alberto Rodolfo
author Petrillo, Ezequiel
author_facet Petrillo, Ezequiel
Godoy Herz, Micaela Amalia
Fuchs, Armin
Reifer, Dominik
Fuller, John
Yanovsky, Marcelo Javier
Simpson, Craig
Brown, John W
Barta, Andrea
Kalyna, Maria
Kornblihtt, Alberto Rodolfo
author_role author
author2 Godoy Herz, Micaela Amalia
Fuchs, Armin
Reifer, Dominik
Fuller, John
Yanovsky, Marcelo Javier
Simpson, Craig
Brown, John W
Barta, Andrea
Kalyna, Maria
Kornblihtt, Alberto Rodolfo
author2_role author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Splicing Alternativo
Plantas
Cloroplasto
Luz/Oscuridad
topic Splicing Alternativo
Plantas
Cloroplasto
Luz/Oscuridad
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Light is a source of energy and also a regulator of plant physiological adaptations. We show here that light/dark conditions affect alternative splicing of a subset of Arabidopsis genes preferentially encoding proteins involved in RNA processing. The effect requires functional chloroplasts and is also observed in roots when the communication with the photosynthetic tissues is not interrupted, suggesting that a signaling molecule travels through the plant. Using photosynthetic electron transfer inhibitors with different mechanisms of action, we deduce that the reduced pool of plastoquinones initiates a chloroplast retrograde signaling that regulates nuclear alternative splicing and is necessary for proper plant responses to varying light conditions.
Fil: Petrillo, Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
Fil: Godoy Herz, Micaela Amalia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
Fil: Fuchs, Armin. Medical University of Vienna. Max F. Perutz Laboratories; Austria
Fil: Reifer, Dominik. Medical University of Vienna. Max F. Perutz Laboratories; Austria
Fil: Fuller, John. The James Hutton Institute. Cell and Molecular Sciences; Reino Unido
Fil: Yanovsky, Marcelo Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; Argentina. Fundación Instituto Leloir; Argentina
Fil: Simpson, Craig. The James Hutton Institute. Cell and Molecular Sciences; Reino Unido
Fil: Brown, John W. The James Hutton Institute. Cell and Molecular Sciences; Reino Unido
Fil: Barta, Andrea. Medical University of Vienna. Max F. Perutz Laboratories; Austria
Fil: Kalyna, Maria. Medical University of Vienna. Max F. Perutz Laboratories; Austria
Fil: Kornblihtt, Alberto Rodolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
description Light is a source of energy and also a regulator of plant physiological adaptations. We show here that light/dark conditions affect alternative splicing of a subset of Arabidopsis genes preferentially encoding proteins involved in RNA processing. The effect requires functional chloroplasts and is also observed in roots when the communication with the photosynthetic tissues is not interrupted, suggesting that a signaling molecule travels through the plant. Using photosynthetic electron transfer inhibitors with different mechanisms of action, we deduce that the reduced pool of plastoquinones initiates a chloroplast retrograde signaling that regulates nuclear alternative splicing and is necessary for proper plant responses to varying light conditions.
publishDate 2014
dc.date.none.fl_str_mv 2014-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/8917
Petrillo, Ezequiel; Godoy Herz, Micaela Amalia; Fuchs, Armin; Reifer, Dominik; Fuller, John; et al.; A chloroplast retrograde signal regulates nuclear alternative splicing; American Association For The Advancement Of Science; Science; 344; 6182; 4-2014; 427-430
0036-8075
url http://hdl.handle.net/11336/8917
identifier_str_mv Petrillo, Ezequiel; Godoy Herz, Micaela Amalia; Fuchs, Armin; Reifer, Dominik; Fuller, John; et al.; A chloroplast retrograde signal regulates nuclear alternative splicing; American Association For The Advancement Of Science; Science; 344; 6182; 4-2014; 427-430
0036-8075
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://science.sciencemag.org/content/344/6182/427
info:eu-repo/semantics/altIdentifier/doi/10.1126/science.1250322
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Association For The Advancement Of Science
publisher.none.fl_str_mv American Association For The Advancement Of Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846083387813527552
score 13.22299

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