Metagenomics for accelerated discovery of antimicrobial compounds: A review focused on bovine mastitis

Autores
Cerioli, Maria Florencia; Moliva, Melina Vanesa; Reinoso, Elina Beatríz
Año de publicación
2024
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Bovine mastitis is the most common disease in dairy cattle worldwide and causes high economic losses to the dairy industry. It can be caused by different microorganisms, as bacteria, fungi, and algae. However, most of these infections are caused by bacteria which have been classified as contagious, opportunistic, and environmental pathogens. Prevention and treatment strategies for bovine mastitis rely primarily on antibiotic therapy. Although it has a positive impact on the dairy industry by contributing to udder health and milk production, it is not always effective. In addition, antimicrobial resistance is also a serious health problem and generates economic losses of billions of dollars. In recent years, there has been a notable increase in interest in the exploration of new antimicrobial compounds from different environments. The soil stands out as a prolific reservoir teeming with enzymes, antibiotics, and natural products. On the other hand, the use of metagenomic approaches allows the identification of a wide range of antimicrobial compounds isolated from soil. This review addresses the potential of metagenomics as a key tool to accelerate the discovery of new antimicrobial compounds, which could have potential applications in the treatment of bovine mastitis.
Fil: Cerioli, Maria Florencia. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Instituto de Biotecnología Ambiental y Salud - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Biotecnología Ambiental y Salud; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; Argentina
Fil: Moliva, Melina Vanesa. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Instituto de Biotecnología Ambiental y Salud - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Biotecnología Ambiental y Salud; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; Argentina
Fil: Reinoso, Elina Beatríz. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Instituto de Biotecnología Ambiental y Salud - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Biotecnología Ambiental y Salud; Argentina
Materia
BOVINE MASTITIS
SOIL
ANTIMICROBIAL COMPOUNDS
METAGENOMIC APPROACH
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/266411
Acceder
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network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Metagenomics for accelerated discovery of antimicrobial compounds: A review focused on bovine mastitisCerioli, Maria FlorenciaMoliva, Melina VanesaReinoso, Elina BeatrízBOVINE MASTITISSOILANTIMICROBIAL COMPOUNDSMETAGENOMIC APPROACHhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Bovine mastitis is the most common disease in dairy cattle worldwide and causes high economic losses to the dairy industry. It can be caused by different microorganisms, as bacteria, fungi, and algae. However, most of these infections are caused by bacteria which have been classified as contagious, opportunistic, and environmental pathogens. Prevention and treatment strategies for bovine mastitis rely primarily on antibiotic therapy. Although it has a positive impact on the dairy industry by contributing to udder health and milk production, it is not always effective. In addition, antimicrobial resistance is also a serious health problem and generates economic losses of billions of dollars. In recent years, there has been a notable increase in interest in the exploration of new antimicrobial compounds from different environments. The soil stands out as a prolific reservoir teeming with enzymes, antibiotics, and natural products. On the other hand, the use of metagenomic approaches allows the identification of a wide range of antimicrobial compounds isolated from soil. This review addresses the potential of metagenomics as a key tool to accelerate the discovery of new antimicrobial compounds, which could have potential applications in the treatment of bovine mastitis.Fil: Cerioli, Maria Florencia. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Instituto de Biotecnología Ambiental y Salud - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Biotecnología Ambiental y Salud; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; ArgentinaFil: Moliva, Melina Vanesa. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Instituto de Biotecnología Ambiental y Salud - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Biotecnología Ambiental y Salud; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; ArgentinaFil: Reinoso, Elina Beatríz. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Instituto de Biotecnología Ambiental y Salud - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Biotecnología Ambiental y Salud; ArgentinaElsevier2024-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/266411Cerioli, Maria Florencia; Moliva, Melina Vanesa; Reinoso, Elina Beatríz; Metagenomics for accelerated discovery of antimicrobial compounds: A review focused on bovine mastitis; Elsevier; The Microbe; 5; 12-2024; 1-92950-1946CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S2950194624001444info:eu-repo/semantics/altIdentifier/doi/10.1016/j.microb.2024.100177info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:25:04Zoai:ri.conicet.gov.ar:11336/266411instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:25:05.305CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Metagenomics for accelerated discovery of antimicrobial compounds: A review focused on bovine mastitis
title Metagenomics for accelerated discovery of antimicrobial compounds: A review focused on bovine mastitis
spellingShingle Metagenomics for accelerated discovery of antimicrobial compounds: A review focused on bovine mastitis
Cerioli, Maria Florencia
BOVINE MASTITIS
SOIL
ANTIMICROBIAL COMPOUNDS
METAGENOMIC APPROACH
title_short Metagenomics for accelerated discovery of antimicrobial compounds: A review focused on bovine mastitis
title_full Metagenomics for accelerated discovery of antimicrobial compounds: A review focused on bovine mastitis
title_fullStr Metagenomics for accelerated discovery of antimicrobial compounds: A review focused on bovine mastitis
title_full_unstemmed Metagenomics for accelerated discovery of antimicrobial compounds: A review focused on bovine mastitis
title_sort Metagenomics for accelerated discovery of antimicrobial compounds: A review focused on bovine mastitis
dc.creator.none.fl_str_mv Cerioli, Maria Florencia
Moliva, Melina Vanesa
Reinoso, Elina Beatríz
author Cerioli, Maria Florencia
author_facet Cerioli, Maria Florencia
Moliva, Melina Vanesa
Reinoso, Elina Beatríz
author_role author
author2 Moliva, Melina Vanesa
Reinoso, Elina Beatríz
author2_role author
author
dc.subject.none.fl_str_mv BOVINE MASTITIS
SOIL
ANTIMICROBIAL COMPOUNDS
METAGENOMIC APPROACH
topic BOVINE MASTITIS
SOIL
ANTIMICROBIAL COMPOUNDS
METAGENOMIC APPROACH
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Bovine mastitis is the most common disease in dairy cattle worldwide and causes high economic losses to the dairy industry. It can be caused by different microorganisms, as bacteria, fungi, and algae. However, most of these infections are caused by bacteria which have been classified as contagious, opportunistic, and environmental pathogens. Prevention and treatment strategies for bovine mastitis rely primarily on antibiotic therapy. Although it has a positive impact on the dairy industry by contributing to udder health and milk production, it is not always effective. In addition, antimicrobial resistance is also a serious health problem and generates economic losses of billions of dollars. In recent years, there has been a notable increase in interest in the exploration of new antimicrobial compounds from different environments. The soil stands out as a prolific reservoir teeming with enzymes, antibiotics, and natural products. On the other hand, the use of metagenomic approaches allows the identification of a wide range of antimicrobial compounds isolated from soil. This review addresses the potential of metagenomics as a key tool to accelerate the discovery of new antimicrobial compounds, which could have potential applications in the treatment of bovine mastitis.
Fil: Cerioli, Maria Florencia. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Instituto de Biotecnología Ambiental y Salud - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Biotecnología Ambiental y Salud; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; Argentina
Fil: Moliva, Melina Vanesa. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Instituto de Biotecnología Ambiental y Salud - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Biotecnología Ambiental y Salud; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; Argentina
Fil: Reinoso, Elina Beatríz. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Instituto de Biotecnología Ambiental y Salud - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Biotecnología Ambiental y Salud; Argentina
description Bovine mastitis is the most common disease in dairy cattle worldwide and causes high economic losses to the dairy industry. It can be caused by different microorganisms, as bacteria, fungi, and algae. However, most of these infections are caused by bacteria which have been classified as contagious, opportunistic, and environmental pathogens. Prevention and treatment strategies for bovine mastitis rely primarily on antibiotic therapy. Although it has a positive impact on the dairy industry by contributing to udder health and milk production, it is not always effective. In addition, antimicrobial resistance is also a serious health problem and generates economic losses of billions of dollars. In recent years, there has been a notable increase in interest in the exploration of new antimicrobial compounds from different environments. The soil stands out as a prolific reservoir teeming with enzymes, antibiotics, and natural products. On the other hand, the use of metagenomic approaches allows the identification of a wide range of antimicrobial compounds isolated from soil. This review addresses the potential of metagenomics as a key tool to accelerate the discovery of new antimicrobial compounds, which could have potential applications in the treatment of bovine mastitis.
publishDate 2024
dc.date.none.fl_str_mv 2024-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/266411
Cerioli, Maria Florencia; Moliva, Melina Vanesa; Reinoso, Elina Beatríz; Metagenomics for accelerated discovery of antimicrobial compounds: A review focused on bovine mastitis; Elsevier; The Microbe; 5; 12-2024; 1-9
2950-1946
CONICET Digital
CONICET
url http://hdl.handle.net/11336/266411
identifier_str_mv Cerioli, Maria Florencia; Moliva, Melina Vanesa; Reinoso, Elina Beatríz; Metagenomics for accelerated discovery of antimicrobial compounds: A review focused on bovine mastitis; Elsevier; The Microbe; 5; 12-2024; 1-9
2950-1946
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S2950194624001444
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.microb.2024.100177
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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