Prospective longitudinal cohort of Argentinean patients with progressive supranuclear palsy and corticobasal syndrome: A platform for epidemiological and translational research

Autores
Angel, Maria José; Mizraji, Gabril F.; Gómez Arévalo, Gonzalo; Silvia, Garcia; Gonzalez Toledo, Maria Eugenia; Avale, Maria Elena; Páez Paz, Indiana de María; Falzone, Tomas Luis; Holubiec, Mariana Ines; Peralta, María Cecilia; Sevlever, Gustavo; Mezmezian, Mónica Beatriz; Gershanik, Oscar Samuel; Chade, Anabel; Couto, Juan Blas Marcos
Año de publicación
2025
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) are neurodegenerative disorderswith disabling postural instability, falls and cognitive impairment associated with 4-repeat tau proteinneuropathology. The low prevalence (6/100,000 inhabitants) is estimated with data only from North American,European countries or Japan.Objective: A multicenter initiative for studying the epidemiology and tau biology of Argentinean patients withPSP and CBS and their ovelaps, Consorcio Argentino de Investigaci´on Traslacional en Tauopatias Primarias(CAITauP).Methods: A prospective observational cohort of people with PSP (PwPSP), CBS and PSP/CBS overlaps will belongitudinally studied aiming at recruitment of 75 patients in 3 years. Deep clinical phenotyping, neurocognitivetesting every 12 months, and biosamples collection at baseline are planned. Disease severity will be assessedevery 6 months and history of environmental exposures will be assessed at baseline.Results: 33/75 expected patients with PSP (19) and CBS (14) have been enrolled. Female gender is 56%, meanage 76, with estimated disease duration of 4.73 years. More than 60% of enrolled patients have completed firstvisit and biosamples collection, one patient underwent brain donation, pathological diagnosis of PSP, clinicalRichardson syndrome. Environmental exposures of a preliminary subsample are reported.Conclusions: The CAITauP enrolled a cohort of Argentinean PwPSP for deep clinical phenotyping and biobanking.Despite the rarity of PSP/CBS, we highlight the feasibility of establishing local cohorts in developing countries fortranslational research. The consortium aims to address underrepresented groups of Argentinean to improvediagnosis, treatment, and to create trial-ready cohorts.
Fil: Angel, Maria José. Instituto de Neurología Cognitiva. Departamento de Neurociencias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina
Fil: Mizraji, Gabril F.. Instituto de Neurología Cognitiva; Argentina
Fil: Gómez Arévalo, Gonzalo. Instituto de Neurología Cognitiva. Departamento de Neurociencias; Argentina
Fil: Silvia, Garcia. Instituto de Neurología Cognitiva. Departamento de Neurociencias; Argentina
Fil: Gonzalez Toledo, Maria Eugenia. Instituto de Neurología Cognitiva; Argentina
Fil: Avale, Maria Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina
Fil: Páez Paz, Indiana de María. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina
Fil: Falzone, Tomas Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; Argentina
Fil: Holubiec, Mariana Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; Argentina
Fil: Peralta, María Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; Argentina
Fil: Sevlever, Gustavo. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Mezmezian, Mónica Beatriz. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Gershanik, Oscar Samuel. Instituto de Neurología Cognitiva. Departamento de Neurociencias; Argentina
Fil: Chade, Anabel. Instituto de Neurología Cognitiva; Argentina
Fil: Couto, Juan Blas Marcos. Instituto de Neurología Cognitiva. Departamento de Neurociencias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Investigaciones en Energía no Convencional. Universidad Nacional de Salta. Facultad de Ciencias Exactas. Departamento de Física. Instituto de Investigaciones en Energía no Convencional; Argentina
Materia
Progressive supranuclear palsy
Corticobasal syndrome
Biobank
Longitudinal cohort
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/280842
Acceder
id CONICETDig_06b7b763e2449020dc123fb0d9da3b15
oai_identifier_str oai:ri.conicet.gov.ar:11336/280842
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Prospective longitudinal cohort of Argentinean patients with progressive supranuclear palsy and corticobasal syndrome: A platform for epidemiological and translational researchAngel, Maria JoséMizraji, Gabril F.Gómez Arévalo, GonzaloSilvia, GarciaGonzalez Toledo, Maria EugeniaAvale, Maria ElenaPáez Paz, Indiana de MaríaFalzone, Tomas LuisHolubiec, Mariana InesPeralta, María CeciliaSevlever, GustavoMezmezian, Mónica BeatrizGershanik, Oscar SamuelChade, AnabelCouto, Juan Blas MarcosProgressive supranuclear palsyCorticobasal syndromeBiobankLongitudinal cohorthttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Background: Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) are neurodegenerative disorderswith disabling postural instability, falls and cognitive impairment associated with 4-repeat tau proteinneuropathology. The low prevalence (6/100,000 inhabitants) is estimated with data only from North American,European countries or Japan.Objective: A multicenter initiative for studying the epidemiology and tau biology of Argentinean patients withPSP and CBS and their ovelaps, Consorcio Argentino de Investigaci´on Traslacional en Tauopatias Primarias(CAITauP).Methods: A prospective observational cohort of people with PSP (PwPSP), CBS and PSP/CBS overlaps will belongitudinally studied aiming at recruitment of 75 patients in 3 years. Deep clinical phenotyping, neurocognitivetesting every 12 months, and biosamples collection at baseline are planned. Disease severity will be assessedevery 6 months and history of environmental exposures will be assessed at baseline.Results: 33/75 expected patients with PSP (19) and CBS (14) have been enrolled. Female gender is 56%, meanage 76, with estimated disease duration of 4.73 years. More than 60% of enrolled patients have completed firstvisit and biosamples collection, one patient underwent brain donation, pathological diagnosis of PSP, clinicalRichardson syndrome. Environmental exposures of a preliminary subsample are reported.Conclusions: The CAITauP enrolled a cohort of Argentinean PwPSP for deep clinical phenotyping and biobanking.Despite the rarity of PSP/CBS, we highlight the feasibility of establishing local cohorts in developing countries fortranslational research. The consortium aims to address underrepresented groups of Argentinean to improvediagnosis, treatment, and to create trial-ready cohorts.Fil: Angel, Maria José. Instituto de Neurología Cognitiva. Departamento de Neurociencias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; ArgentinaFil: Mizraji, Gabril F.. Instituto de Neurología Cognitiva; ArgentinaFil: Gómez Arévalo, Gonzalo. Instituto de Neurología Cognitiva. Departamento de Neurociencias; ArgentinaFil: Silvia, Garcia. Instituto de Neurología Cognitiva. Departamento de Neurociencias; ArgentinaFil: Gonzalez Toledo, Maria Eugenia. Instituto de Neurología Cognitiva; ArgentinaFil: Avale, Maria Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; ArgentinaFil: Páez Paz, Indiana de María. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; ArgentinaFil: Falzone, Tomas Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; ArgentinaFil: Holubiec, Mariana Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; ArgentinaFil: Peralta, María Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; ArgentinaFil: Sevlever, Gustavo. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Mezmezian, Mónica Beatriz. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Gershanik, Oscar Samuel. Instituto de Neurología Cognitiva. Departamento de Neurociencias; ArgentinaFil: Chade, Anabel. Instituto de Neurología Cognitiva; ArgentinaFil: Couto, Juan Blas Marcos. Instituto de Neurología Cognitiva. Departamento de Neurociencias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Investigaciones en Energía no Convencional. Universidad Nacional de Salta. Facultad de Ciencias Exactas. Departamento de Física. Instituto de Investigaciones en Energía no Convencional; ArgentinaElsevier2025-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/280842Angel, Maria José; Mizraji, Gabril F.; Gómez Arévalo, Gonzalo; Silvia, Garcia; Gonzalez Toledo, Maria Eugenia; et al.; Prospective longitudinal cohort of Argentinean patients with progressive supranuclear palsy and corticobasal syndrome: A platform for epidemiological and translational research; Elsevier; Clinical Parkinsonism & Related Disorders; 12; 100339; 7-2025; 1-52590-1125CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S259011252500043Xinfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.prdoa.2025.100339info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2026-02-26T10:30:50Zoai:ri.conicet.gov.ar:11336/280842instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982026-02-26 10:30:51.13CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Prospective longitudinal cohort of Argentinean patients with progressive supranuclear palsy and corticobasal syndrome: A platform for epidemiological and translational research
title Prospective longitudinal cohort of Argentinean patients with progressive supranuclear palsy and corticobasal syndrome: A platform for epidemiological and translational research
spellingShingle Prospective longitudinal cohort of Argentinean patients with progressive supranuclear palsy and corticobasal syndrome: A platform for epidemiological and translational research
Angel, Maria José
Progressive supranuclear palsy
Corticobasal syndrome
Biobank
Longitudinal cohort
title_short Prospective longitudinal cohort of Argentinean patients with progressive supranuclear palsy and corticobasal syndrome: A platform for epidemiological and translational research
title_full Prospective longitudinal cohort of Argentinean patients with progressive supranuclear palsy and corticobasal syndrome: A platform for epidemiological and translational research
title_fullStr Prospective longitudinal cohort of Argentinean patients with progressive supranuclear palsy and corticobasal syndrome: A platform for epidemiological and translational research
title_full_unstemmed Prospective longitudinal cohort of Argentinean patients with progressive supranuclear palsy and corticobasal syndrome: A platform for epidemiological and translational research
title_sort Prospective longitudinal cohort of Argentinean patients with progressive supranuclear palsy and corticobasal syndrome: A platform for epidemiological and translational research
dc.creator.none.fl_str_mv Angel, Maria José
Mizraji, Gabril F.
Gómez Arévalo, Gonzalo
Silvia, Garcia
Gonzalez Toledo, Maria Eugenia
Avale, Maria Elena
Páez Paz, Indiana de María
Falzone, Tomas Luis
Holubiec, Mariana Ines
Peralta, María Cecilia
Sevlever, Gustavo
Mezmezian, Mónica Beatriz
Gershanik, Oscar Samuel
Chade, Anabel
Couto, Juan Blas Marcos
author Angel, Maria José
author_facet Angel, Maria José
Mizraji, Gabril F.
Gómez Arévalo, Gonzalo
Silvia, Garcia
Gonzalez Toledo, Maria Eugenia
Avale, Maria Elena
Páez Paz, Indiana de María
Falzone, Tomas Luis
Holubiec, Mariana Ines
Peralta, María Cecilia
Sevlever, Gustavo
Mezmezian, Mónica Beatriz
Gershanik, Oscar Samuel
Chade, Anabel
Couto, Juan Blas Marcos
author_role author
author2 Mizraji, Gabril F.
Gómez Arévalo, Gonzalo
Silvia, Garcia
Gonzalez Toledo, Maria Eugenia
Avale, Maria Elena
Páez Paz, Indiana de María
Falzone, Tomas Luis
Holubiec, Mariana Ines
Peralta, María Cecilia
Sevlever, Gustavo
Mezmezian, Mónica Beatriz
Gershanik, Oscar Samuel
Chade, Anabel
Couto, Juan Blas Marcos
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Progressive supranuclear palsy
Corticobasal syndrome
Biobank
Longitudinal cohort
topic Progressive supranuclear palsy
Corticobasal syndrome
Biobank
Longitudinal cohort
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Background: Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) are neurodegenerative disorderswith disabling postural instability, falls and cognitive impairment associated with 4-repeat tau proteinneuropathology. The low prevalence (6/100,000 inhabitants) is estimated with data only from North American,European countries or Japan.Objective: A multicenter initiative for studying the epidemiology and tau biology of Argentinean patients withPSP and CBS and their ovelaps, Consorcio Argentino de Investigaci´on Traslacional en Tauopatias Primarias(CAITauP).Methods: A prospective observational cohort of people with PSP (PwPSP), CBS and PSP/CBS overlaps will belongitudinally studied aiming at recruitment of 75 patients in 3 years. Deep clinical phenotyping, neurocognitivetesting every 12 months, and biosamples collection at baseline are planned. Disease severity will be assessedevery 6 months and history of environmental exposures will be assessed at baseline.Results: 33/75 expected patients with PSP (19) and CBS (14) have been enrolled. Female gender is 56%, meanage 76, with estimated disease duration of 4.73 years. More than 60% of enrolled patients have completed firstvisit and biosamples collection, one patient underwent brain donation, pathological diagnosis of PSP, clinicalRichardson syndrome. Environmental exposures of a preliminary subsample are reported.Conclusions: The CAITauP enrolled a cohort of Argentinean PwPSP for deep clinical phenotyping and biobanking.Despite the rarity of PSP/CBS, we highlight the feasibility of establishing local cohorts in developing countries fortranslational research. The consortium aims to address underrepresented groups of Argentinean to improvediagnosis, treatment, and to create trial-ready cohorts.
Fil: Angel, Maria José. Instituto de Neurología Cognitiva. Departamento de Neurociencias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina
Fil: Mizraji, Gabril F.. Instituto de Neurología Cognitiva; Argentina
Fil: Gómez Arévalo, Gonzalo. Instituto de Neurología Cognitiva. Departamento de Neurociencias; Argentina
Fil: Silvia, Garcia. Instituto de Neurología Cognitiva. Departamento de Neurociencias; Argentina
Fil: Gonzalez Toledo, Maria Eugenia. Instituto de Neurología Cognitiva; Argentina
Fil: Avale, Maria Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina
Fil: Páez Paz, Indiana de María. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina
Fil: Falzone, Tomas Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; Argentina
Fil: Holubiec, Mariana Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; Argentina
Fil: Peralta, María Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; Argentina
Fil: Sevlever, Gustavo. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Mezmezian, Mónica Beatriz. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Gershanik, Oscar Samuel. Instituto de Neurología Cognitiva. Departamento de Neurociencias; Argentina
Fil: Chade, Anabel. Instituto de Neurología Cognitiva; Argentina
Fil: Couto, Juan Blas Marcos. Instituto de Neurología Cognitiva. Departamento de Neurociencias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Investigaciones en Energía no Convencional. Universidad Nacional de Salta. Facultad de Ciencias Exactas. Departamento de Física. Instituto de Investigaciones en Energía no Convencional; Argentina
description Background: Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) are neurodegenerative disorderswith disabling postural instability, falls and cognitive impairment associated with 4-repeat tau proteinneuropathology. The low prevalence (6/100,000 inhabitants) is estimated with data only from North American,European countries or Japan.Objective: A multicenter initiative for studying the epidemiology and tau biology of Argentinean patients withPSP and CBS and their ovelaps, Consorcio Argentino de Investigaci´on Traslacional en Tauopatias Primarias(CAITauP).Methods: A prospective observational cohort of people with PSP (PwPSP), CBS and PSP/CBS overlaps will belongitudinally studied aiming at recruitment of 75 patients in 3 years. Deep clinical phenotyping, neurocognitivetesting every 12 months, and biosamples collection at baseline are planned. Disease severity will be assessedevery 6 months and history of environmental exposures will be assessed at baseline.Results: 33/75 expected patients with PSP (19) and CBS (14) have been enrolled. Female gender is 56%, meanage 76, with estimated disease duration of 4.73 years. More than 60% of enrolled patients have completed firstvisit and biosamples collection, one patient underwent brain donation, pathological diagnosis of PSP, clinicalRichardson syndrome. Environmental exposures of a preliminary subsample are reported.Conclusions: The CAITauP enrolled a cohort of Argentinean PwPSP for deep clinical phenotyping and biobanking.Despite the rarity of PSP/CBS, we highlight the feasibility of establishing local cohorts in developing countries fortranslational research. The consortium aims to address underrepresented groups of Argentinean to improvediagnosis, treatment, and to create trial-ready cohorts.
publishDate 2025
dc.date.none.fl_str_mv 2025-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/280842
Angel, Maria José; Mizraji, Gabril F.; Gómez Arévalo, Gonzalo; Silvia, Garcia; Gonzalez Toledo, Maria Eugenia; et al.; Prospective longitudinal cohort of Argentinean patients with progressive supranuclear palsy and corticobasal syndrome: A platform for epidemiological and translational research; Elsevier; Clinical Parkinsonism & Related Disorders; 12; 100339; 7-2025; 1-5
2590-1125
CONICET Digital
CONICET
url http://hdl.handle.net/11336/280842
identifier_str_mv Angel, Maria José; Mizraji, Gabril F.; Gómez Arévalo, Gonzalo; Silvia, Garcia; Gonzalez Toledo, Maria Eugenia; et al.; Prospective longitudinal cohort of Argentinean patients with progressive supranuclear palsy and corticobasal syndrome: A platform for epidemiological and translational research; Elsevier; Clinical Parkinsonism & Related Disorders; 12; 100339; 7-2025; 1-5
2590-1125
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S259011252500043X
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.prdoa.2025.100339
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.665996

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