Chagas disease, a risk factor for high blood pressure

Autores
Vicco, Miguel Hernán; Rodeles Antonelli, Luz María; Yodice, Agustina; Marcipar, Iván Sergio
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: Chagas disease is a parasite infection caused by the protozoan Trypanosoma cruzi. Its most common complications is chronic Chagas heart disease but impairments of the systemic vasculature also has been observed. Although the different mechanisms that regulate blood pressure are disrupted, to our knowledge data on the association of hypertension and chronic Chagas disease are scarce. In this regard we evaluate whether Chagas disease constitutes a high blood pressure risk factor. Materials and methods: We recruited 200 individuals, half of them with positive serology for T. cruzi. They were subjected to a complete clinical examination. Results: The mean age of sampled individuals was 46.7 ± 12.3, and the mean of systolic and diastolic blood pressure were 124 ± 12 mmHg and 82 ± 10 mmHg, respectively. There were no between-group differences regarding age, sex distribution or body mass index. Chagas disease contributed significantly to high blood pressure (OR = 4, 95% CI 1.8323–7.0864, p = 0.0002). Conclusion: Our results reveal an important association between Chagas disease and high blood pressure, which should be contemplated by physicians in order to promote preventive cardiovascular actions in patients with Chagas disease.
Fil: Vicco, Miguel Hernán. Universidad Nacional del Litoral. Facultad de Ciencias Médicas; Argentina. Provincia de Santa Fe. Ministerio de Salud. Hospital J. B. Iturraspe; Argentina. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Laboratorio de Tecnología Inmunológica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina
Fil: Rodeles Antonelli, Luz María. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Laboratorio de Tecnología Inmunológica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Provincia de Santa Fe. Ministerio de Salud. Hospital J. B. Iturraspe; Argentina
Fil: Yodice, Agustina. Provincia de Santa Fe. Ministerio de Salud. Hospital J. B. Iturraspe; Argentina
Fil: Marcipar, Iván Sergio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Laboratorio de Tecnología Inmunológica; Argentina
Materia
Hypertension
Risk Factor
Vascular Disease
Chagas Disease
Association
Blood Pressure
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/31401
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/31401
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Chagas disease, a risk factor for high blood pressureVicco, Miguel HernánRodeles Antonelli, Luz MaríaYodice, AgustinaMarcipar, Iván SergioHypertensionRisk FactorVascular DiseaseChagas DiseaseAssociationBlood Pressurehttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Background: Chagas disease is a parasite infection caused by the protozoan Trypanosoma cruzi. Its most common complications is chronic Chagas heart disease but impairments of the systemic vasculature also has been observed. Although the different mechanisms that regulate blood pressure are disrupted, to our knowledge data on the association of hypertension and chronic Chagas disease are scarce. In this regard we evaluate whether Chagas disease constitutes a high blood pressure risk factor. Materials and methods: We recruited 200 individuals, half of them with positive serology for T. cruzi. They were subjected to a complete clinical examination. Results: The mean age of sampled individuals was 46.7 ± 12.3, and the mean of systolic and diastolic blood pressure were 124 ± 12 mmHg and 82 ± 10 mmHg, respectively. There were no between-group differences regarding age, sex distribution or body mass index. Chagas disease contributed significantly to high blood pressure (OR = 4, 95% CI 1.8323–7.0864, p = 0.0002). Conclusion: Our results reveal an important association between Chagas disease and high blood pressure, which should be contemplated by physicians in order to promote preventive cardiovascular actions in patients with Chagas disease.Fil: Vicco, Miguel Hernán. Universidad Nacional del Litoral. Facultad de Ciencias Médicas; Argentina. Provincia de Santa Fe. Ministerio de Salud. Hospital J. B. Iturraspe; Argentina. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Laboratorio de Tecnología Inmunológica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; ArgentinaFil: Rodeles Antonelli, Luz María. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Laboratorio de Tecnología Inmunológica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Provincia de Santa Fe. Ministerio de Salud. Hospital J. B. Iturraspe; ArgentinaFil: Yodice, Agustina. Provincia de Santa Fe. Ministerio de Salud. Hospital J. B. Iturraspe; ArgentinaFil: Marcipar, Iván Sergio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Laboratorio de Tecnología Inmunológica; ArgentinaTaylor & Francis2014-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/31401Vicco, Miguel Hernán; Rodeles Antonelli, Luz María; Yodice, Agustina; Marcipar, Iván Sergio; Chagas disease, a risk factor for high blood pressure; Taylor & Francis; Blood Pressure; 23; 6; 4-2014; 245-3480803-7051CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.3109/08037051.2014.907977info:eu-repo/semantics/altIdentifier/url/http://www.tandfonline.com/doi/full/10.3109/08037051.2014.907977info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:44:53Zoai:ri.conicet.gov.ar:11336/31401instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:44:54.015CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Chagas disease, a risk factor for high blood pressure
title Chagas disease, a risk factor for high blood pressure
spellingShingle Chagas disease, a risk factor for high blood pressure
Vicco, Miguel Hernán
Hypertension
Risk Factor
Vascular Disease
Chagas Disease
Association
Blood Pressure
title_short Chagas disease, a risk factor for high blood pressure
title_full Chagas disease, a risk factor for high blood pressure
title_fullStr Chagas disease, a risk factor for high blood pressure
title_full_unstemmed Chagas disease, a risk factor for high blood pressure
title_sort Chagas disease, a risk factor for high blood pressure
dc.creator.none.fl_str_mv Vicco, Miguel Hernán
Rodeles Antonelli, Luz María
Yodice, Agustina
Marcipar, Iván Sergio
author Vicco, Miguel Hernán
author_facet Vicco, Miguel Hernán
Rodeles Antonelli, Luz María
Yodice, Agustina
Marcipar, Iván Sergio
author_role author
author2 Rodeles Antonelli, Luz María
Yodice, Agustina
Marcipar, Iván Sergio
author2_role author
author
author
dc.subject.none.fl_str_mv Hypertension
Risk Factor
Vascular Disease
Chagas Disease
Association
Blood Pressure
topic Hypertension
Risk Factor
Vascular Disease
Chagas Disease
Association
Blood Pressure
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Background: Chagas disease is a parasite infection caused by the protozoan Trypanosoma cruzi. Its most common complications is chronic Chagas heart disease but impairments of the systemic vasculature also has been observed. Although the different mechanisms that regulate blood pressure are disrupted, to our knowledge data on the association of hypertension and chronic Chagas disease are scarce. In this regard we evaluate whether Chagas disease constitutes a high blood pressure risk factor. Materials and methods: We recruited 200 individuals, half of them with positive serology for T. cruzi. They were subjected to a complete clinical examination. Results: The mean age of sampled individuals was 46.7 ± 12.3, and the mean of systolic and diastolic blood pressure were 124 ± 12 mmHg and 82 ± 10 mmHg, respectively. There were no between-group differences regarding age, sex distribution or body mass index. Chagas disease contributed significantly to high blood pressure (OR = 4, 95% CI 1.8323–7.0864, p = 0.0002). Conclusion: Our results reveal an important association between Chagas disease and high blood pressure, which should be contemplated by physicians in order to promote preventive cardiovascular actions in patients with Chagas disease.
Fil: Vicco, Miguel Hernán. Universidad Nacional del Litoral. Facultad de Ciencias Médicas; Argentina. Provincia de Santa Fe. Ministerio de Salud. Hospital J. B. Iturraspe; Argentina. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Laboratorio de Tecnología Inmunológica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina
Fil: Rodeles Antonelli, Luz María. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Laboratorio de Tecnología Inmunológica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Provincia de Santa Fe. Ministerio de Salud. Hospital J. B. Iturraspe; Argentina
Fil: Yodice, Agustina. Provincia de Santa Fe. Ministerio de Salud. Hospital J. B. Iturraspe; Argentina
Fil: Marcipar, Iván Sergio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Laboratorio de Tecnología Inmunológica; Argentina
description Background: Chagas disease is a parasite infection caused by the protozoan Trypanosoma cruzi. Its most common complications is chronic Chagas heart disease but impairments of the systemic vasculature also has been observed. Although the different mechanisms that regulate blood pressure are disrupted, to our knowledge data on the association of hypertension and chronic Chagas disease are scarce. In this regard we evaluate whether Chagas disease constitutes a high blood pressure risk factor. Materials and methods: We recruited 200 individuals, half of them with positive serology for T. cruzi. They were subjected to a complete clinical examination. Results: The mean age of sampled individuals was 46.7 ± 12.3, and the mean of systolic and diastolic blood pressure were 124 ± 12 mmHg and 82 ± 10 mmHg, respectively. There were no between-group differences regarding age, sex distribution or body mass index. Chagas disease contributed significantly to high blood pressure (OR = 4, 95% CI 1.8323–7.0864, p = 0.0002). Conclusion: Our results reveal an important association between Chagas disease and high blood pressure, which should be contemplated by physicians in order to promote preventive cardiovascular actions in patients with Chagas disease.
publishDate 2014
dc.date.none.fl_str_mv 2014-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/31401
Vicco, Miguel Hernán; Rodeles Antonelli, Luz María; Yodice, Agustina; Marcipar, Iván Sergio; Chagas disease, a risk factor for high blood pressure; Taylor & Francis; Blood Pressure; 23; 6; 4-2014; 245-348
0803-7051
CONICET Digital
CONICET
url http://hdl.handle.net/11336/31401
identifier_str_mv Vicco, Miguel Hernán; Rodeles Antonelli, Luz María; Yodice, Agustina; Marcipar, Iván Sergio; Chagas disease, a risk factor for high blood pressure; Taylor & Francis; Blood Pressure; 23; 6; 4-2014; 245-348
0803-7051
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.3109/08037051.2014.907977
info:eu-repo/semantics/altIdentifier/url/http://www.tandfonline.com/doi/full/10.3109/08037051.2014.907977
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Taylor & Francis
publisher.none.fl_str_mv Taylor & Francis
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846082960251420672
score 13.22299

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