Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival

Autores
Byun, Jung S.; Singhal, Sandeep K.; Park, Samson; Yi, Dae Ik; Yan, Tingfen; Caban, Ambar; Jones, Alana; Mukhopadhyay, Partha; Gille, Sarah; Hewitt, Stephen M.; Newman, Lisa; Davis, Melissa B.; Jenkins, Brittany D.; Sepulveda, Jorge L.; de Siervi, Adriana; Nápoles, Anna María; Vohra, Nasreen A.; Gardner, Kevin
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Compared with their European American (EA) counterparts, African American (AA) women are more likely to die from breast cancer in the United States. This disparity is greatest in hormone receptor-positive subtypes. Here we uncover biological factors underlying this disparity by comparing functional expression and prognostic significance of master transcriptional regulators of luminal differentiation.
Fil: Byun, Jung S.. National Institutes of Health; Estados Unidos
Fil: Singhal, Sandeep K.. Columbia University; Estados Unidos
Fil: Park, Samson. National Institutes of Health; Estados Unidos
Fil: Yi, Dae Ik. National Institutes of Health; Estados Unidos
Fil: Yan, Tingfen. National Institutes of Health; Estados Unidos
Fil: Caban, Ambar. Columbia University Medical Center; Estados Unidos
Fil: Jones, Alana. National Institutes of Health; Estados Unidos
Fil: Mukhopadhyay, Partha. Columbia University Medical Center; Estados Unidos
Fil: Gille, Sarah. National Institutes of Health; Estados Unidos
Fil: Hewitt, Stephen M.. No especifíca;
Fil: Newman, Lisa. No especifíca;
Fil: Davis, Melissa B.. Henry Ford Health System; Estados Unidos
Fil: Jenkins, Brittany D.. Henry Ford Health System; Estados Unidos
Fil: Sepulveda, Jorge L.. Columbia University Medical Center; Estados Unidos
Fil: de Siervi, Adriana. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Nápoles, Anna María. National Institute On Minority Health And Health Disparities; Estados Unidos
Fil: Vohra, Nasreen A.. East Carolina University; Estados Unidos
Fil: Gardner, Kevin. Columbia University Medical Center; Estados Unidos
Materia
BREAST CANCER
GENE EXPRESSION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/109427
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/109427
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer SurvivalByun, Jung S.Singhal, Sandeep K.Park, SamsonYi, Dae IkYan, TingfenCaban, AmbarJones, AlanaMukhopadhyay, ParthaGille, SarahHewitt, Stephen M.Newman, LisaDavis, Melissa B.Jenkins, Brittany D.Sepulveda, Jorge L.de Siervi, AdrianaNápoles, Anna MaríaVohra, Nasreen A.Gardner, KevinBREAST CANCERGENE EXPRESSIONhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Compared with their European American (EA) counterparts, African American (AA) women are more likely to die from breast cancer in the United States. This disparity is greatest in hormone receptor-positive subtypes. Here we uncover biological factors underlying this disparity by comparing functional expression and prognostic significance of master transcriptional regulators of luminal differentiation.Fil: Byun, Jung S.. National Institutes of Health; Estados UnidosFil: Singhal, Sandeep K.. Columbia University; Estados UnidosFil: Park, Samson. National Institutes of Health; Estados UnidosFil: Yi, Dae Ik. National Institutes of Health; Estados UnidosFil: Yan, Tingfen. National Institutes of Health; Estados UnidosFil: Caban, Ambar. Columbia University Medical Center; Estados UnidosFil: Jones, Alana. National Institutes of Health; Estados UnidosFil: Mukhopadhyay, Partha. Columbia University Medical Center; Estados UnidosFil: Gille, Sarah. National Institutes of Health; Estados UnidosFil: Hewitt, Stephen M.. No especifíca;Fil: Newman, Lisa. No especifíca;Fil: Davis, Melissa B.. Henry Ford Health System; Estados UnidosFil: Jenkins, Brittany D.. Henry Ford Health System; Estados UnidosFil: Sepulveda, Jorge L.. Columbia University Medical Center; Estados UnidosFil: de Siervi, Adriana. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Nápoles, Anna María. National Institute On Minority Health And Health Disparities; Estados UnidosFil: Vohra, Nasreen A.. East Carolina University; Estados UnidosFil: Gardner, Kevin. Columbia University Medical Center; Estados UnidosAmerican Association for Cancer Research2020-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/109427Byun, Jung S.; Singhal, Sandeep K.; Park, Samson; Yi, Dae Ik; Yan, Tingfen; et al.; Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival; American Association for Cancer Research; Clinical Cancer Research; 26; 8; 4-2020; 1905-19141078-0432CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://clincancerres.aacrjournals.org/content/26/8/1905.longinfo:eu-repo/semantics/altIdentifier/doi/10.1158/1078-0432.CCR-19-0875info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T12:06:04Zoai:ri.conicet.gov.ar:11336/109427instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 12:06:04.474CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival
title Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival
spellingShingle Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival
Byun, Jung S.
BREAST CANCER
GENE EXPRESSION
title_short Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival
title_full Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival
title_fullStr Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival
title_full_unstemmed Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival
title_sort Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival
dc.creator.none.fl_str_mv Byun, Jung S.
Singhal, Sandeep K.
Park, Samson
Yi, Dae Ik
Yan, Tingfen
Caban, Ambar
Jones, Alana
Mukhopadhyay, Partha
Gille, Sarah
Hewitt, Stephen M.
Newman, Lisa
Davis, Melissa B.
Jenkins, Brittany D.
Sepulveda, Jorge L.
de Siervi, Adriana
Nápoles, Anna María
Vohra, Nasreen A.
Gardner, Kevin
author Byun, Jung S.
author_facet Byun, Jung S.
Singhal, Sandeep K.
Park, Samson
Yi, Dae Ik
Yan, Tingfen
Caban, Ambar
Jones, Alana
Mukhopadhyay, Partha
Gille, Sarah
Hewitt, Stephen M.
Newman, Lisa
Davis, Melissa B.
Jenkins, Brittany D.
Sepulveda, Jorge L.
de Siervi, Adriana
Nápoles, Anna María
Vohra, Nasreen A.
Gardner, Kevin
author_role author
author2 Singhal, Sandeep K.
Park, Samson
Yi, Dae Ik
Yan, Tingfen
Caban, Ambar
Jones, Alana
Mukhopadhyay, Partha
Gille, Sarah
Hewitt, Stephen M.
Newman, Lisa
Davis, Melissa B.
Jenkins, Brittany D.
Sepulveda, Jorge L.
de Siervi, Adriana
Nápoles, Anna María
Vohra, Nasreen A.
Gardner, Kevin
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv BREAST CANCER
GENE EXPRESSION
topic BREAST CANCER
GENE EXPRESSION
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Compared with their European American (EA) counterparts, African American (AA) women are more likely to die from breast cancer in the United States. This disparity is greatest in hormone receptor-positive subtypes. Here we uncover biological factors underlying this disparity by comparing functional expression and prognostic significance of master transcriptional regulators of luminal differentiation.
Fil: Byun, Jung S.. National Institutes of Health; Estados Unidos
Fil: Singhal, Sandeep K.. Columbia University; Estados Unidos
Fil: Park, Samson. National Institutes of Health; Estados Unidos
Fil: Yi, Dae Ik. National Institutes of Health; Estados Unidos
Fil: Yan, Tingfen. National Institutes of Health; Estados Unidos
Fil: Caban, Ambar. Columbia University Medical Center; Estados Unidos
Fil: Jones, Alana. National Institutes of Health; Estados Unidos
Fil: Mukhopadhyay, Partha. Columbia University Medical Center; Estados Unidos
Fil: Gille, Sarah. National Institutes of Health; Estados Unidos
Fil: Hewitt, Stephen M.. No especifíca;
Fil: Newman, Lisa. No especifíca;
Fil: Davis, Melissa B.. Henry Ford Health System; Estados Unidos
Fil: Jenkins, Brittany D.. Henry Ford Health System; Estados Unidos
Fil: Sepulveda, Jorge L.. Columbia University Medical Center; Estados Unidos
Fil: de Siervi, Adriana. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Nápoles, Anna María. National Institute On Minority Health And Health Disparities; Estados Unidos
Fil: Vohra, Nasreen A.. East Carolina University; Estados Unidos
Fil: Gardner, Kevin. Columbia University Medical Center; Estados Unidos
description Compared with their European American (EA) counterparts, African American (AA) women are more likely to die from breast cancer in the United States. This disparity is greatest in hormone receptor-positive subtypes. Here we uncover biological factors underlying this disparity by comparing functional expression and prognostic significance of master transcriptional regulators of luminal differentiation.
publishDate 2020
dc.date.none.fl_str_mv 2020-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/109427
Byun, Jung S.; Singhal, Sandeep K.; Park, Samson; Yi, Dae Ik; Yan, Tingfen; et al.; Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival; American Association for Cancer Research; Clinical Cancer Research; 26; 8; 4-2020; 1905-1914
1078-0432
CONICET Digital
CONICET
url http://hdl.handle.net/11336/109427
identifier_str_mv Byun, Jung S.; Singhal, Sandeep K.; Park, Samson; Yi, Dae Ik; Yan, Tingfen; et al.; Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival; American Association for Cancer Research; Clinical Cancer Research; 26; 8; 4-2020; 1905-1914
1078-0432
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://clincancerres.aacrjournals.org/content/26/8/1905.long
info:eu-repo/semantics/altIdentifier/doi/10.1158/1078-0432.CCR-19-0875
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Association for Cancer Research
publisher.none.fl_str_mv American Association for Cancer Research
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846782415311208448
score 12.982451

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