Argentinian multicenter study on urinary tract infections due to Streptococcus agalactiae in adult patients

Autores
Vigliarolo, Laura; Arias, Bárbara Soledad; Suarez, Mariana; Van Haute, Evert; Kovacec, Verónica Ivana; Lopardo, Horacio Angel; Bonofiglio, Laura; Mollerach, Marta Eugenia
Año de publicación
2019
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Introduction: Streptococcus agalactiae (group B streptococcus, GBS) is a recognized urinary pathogen both in males and pregnant or non-pregnant women. Data regarding GBS serotypes recovered from urinary tract infections (UTIs) are scarce. The aim of this study was to describe the clinical and microbiological characteristics of UTIs caused by GBS in adult patients in Argentina.Methodology: A prospective multicenter study involving 86 centers was conducted in Argentina between July 1st, 2014 and June 30th, 2015. Antimicrobial susceptibility and serotype distribution of GBS isolated from the urinary tract of adult patients were determined. Susceptibility tests were performed by the disk diffusion and/or agar dilution methods. Epidemiological and clinical characteristics of the patients were considered to identify associated comorbilities.Results: Seven hundred and one GBS were sent to the reference laboratory in the above mentioned period, however, only 211 fulfilled our selection criteria (demographic data availability, underlying diseases reported, colony counts greater than 105 CFU/mL, single organism isolated from the urine sample). No penicillin-resistant GBS was found but fluoroquinolone resistance was high (12.8%), especially among GBS isolated from men and non-pregnant women. UTIs due to GBS were associated to underlying diseases in men and non-pregnant women, particularly diabetes mellitus. Most of the isolates showed serotypes Ia and III.Conclusions: GBS are still susceptible to penicillin but fluoroquinolone resistance is a growing concern, at least in Argentina. There are underlying conditions that could be associated to urinary infections caused by GBS.
Fil: Vigliarolo, Laura. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; Argentina
Fil: Arias, Bárbara Soledad. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Microbiología; Argentina
Fil: Suarez, Mariana. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; Argentina
Fil: Van Haute, Evert. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Microbiología; Argentina
Fil: Kovacec, Verónica Ivana. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Microbiología; Argentina
Fil: Lopardo, Horacio Angel. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; Argentina
Fil: Bonofiglio, Laura. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Microbiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Fil: Mollerach, Marta Eugenia. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Microbiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Materia
Urinary Tract infections
Streptococcus agalactiae
group B
Argenina
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/129342
Acceder
id CONICETDig_00cd1fc5db72c99249594e66bcdee797
oai_identifier_str oai:ri.conicet.gov.ar:11336/129342
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Argentinian multicenter study on urinary tract infections due to Streptococcus agalactiae in adult patientsVigliarolo, LauraArias, Bárbara SoledadSuarez, MarianaVan Haute, EvertKovacec, Verónica IvanaLopardo, Horacio AngelBonofiglio, LauraMollerach, Marta EugeniaUrinary Tract infectionsStreptococcus agalactiaegroup BArgeninahttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Introduction: Streptococcus agalactiae (group B streptococcus, GBS) is a recognized urinary pathogen both in males and pregnant or non-pregnant women. Data regarding GBS serotypes recovered from urinary tract infections (UTIs) are scarce. The aim of this study was to describe the clinical and microbiological characteristics of UTIs caused by GBS in adult patients in Argentina.Methodology: A prospective multicenter study involving 86 centers was conducted in Argentina between July 1st, 2014 and June 30th, 2015. Antimicrobial susceptibility and serotype distribution of GBS isolated from the urinary tract of adult patients were determined. Susceptibility tests were performed by the disk diffusion and/or agar dilution methods. Epidemiological and clinical characteristics of the patients were considered to identify associated comorbilities.Results: Seven hundred and one GBS were sent to the reference laboratory in the above mentioned period, however, only 211 fulfilled our selection criteria (demographic data availability, underlying diseases reported, colony counts greater than 105 CFU/mL, single organism isolated from the urine sample). No penicillin-resistant GBS was found but fluoroquinolone resistance was high (12.8%), especially among GBS isolated from men and non-pregnant women. UTIs due to GBS were associated to underlying diseases in men and non-pregnant women, particularly diabetes mellitus. Most of the isolates showed serotypes Ia and III.Conclusions: GBS are still susceptible to penicillin but fluoroquinolone resistance is a growing concern, at least in Argentina. There are underlying conditions that could be associated to urinary infections caused by GBS.Fil: Vigliarolo, Laura. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; ArgentinaFil: Arias, Bárbara Soledad. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Microbiología; ArgentinaFil: Suarez, Mariana. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; ArgentinaFil: Van Haute, Evert. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Microbiología; ArgentinaFil: Kovacec, Verónica Ivana. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Microbiología; ArgentinaFil: Lopardo, Horacio Angel. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; ArgentinaFil: Bonofiglio, Laura. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Microbiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; ArgentinaFil: Mollerach, Marta Eugenia. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Microbiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; ArgentinaThe Journal of Infection in Developing Countries2019-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/129342Vigliarolo, Laura; Arias, Bárbara Soledad; Suarez, Mariana; Van Haute, Evert; Kovacec, Verónica Ivana; et al.; Argentinian multicenter study on urinary tract infections due to Streptococcus agalactiae in adult patients; The Journal of Infection in Developing Countries; The Journal of Infection in Developing Countries; 13; 1; 6-2019; 77-821972-2680CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://jidc.org/index.php/journal/article/view/32032027info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:33:04Zoai:ri.conicet.gov.ar:11336/129342instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:33:05.228CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Argentinian multicenter study on urinary tract infections due to Streptococcus agalactiae in adult patients
title Argentinian multicenter study on urinary tract infections due to Streptococcus agalactiae in adult patients
spellingShingle Argentinian multicenter study on urinary tract infections due to Streptococcus agalactiae in adult patients
Vigliarolo, Laura
Urinary Tract infections
Streptococcus agalactiae
group B
Argenina
title_short Argentinian multicenter study on urinary tract infections due to Streptococcus agalactiae in adult patients
title_full Argentinian multicenter study on urinary tract infections due to Streptococcus agalactiae in adult patients
title_fullStr Argentinian multicenter study on urinary tract infections due to Streptococcus agalactiae in adult patients
title_full_unstemmed Argentinian multicenter study on urinary tract infections due to Streptococcus agalactiae in adult patients
title_sort Argentinian multicenter study on urinary tract infections due to Streptococcus agalactiae in adult patients
dc.creator.none.fl_str_mv Vigliarolo, Laura
Arias, Bárbara Soledad
Suarez, Mariana
Van Haute, Evert
Kovacec, Verónica Ivana
Lopardo, Horacio Angel
Bonofiglio, Laura
Mollerach, Marta Eugenia
author Vigliarolo, Laura
author_facet Vigliarolo, Laura
Arias, Bárbara Soledad
Suarez, Mariana
Van Haute, Evert
Kovacec, Verónica Ivana
Lopardo, Horacio Angel
Bonofiglio, Laura
Mollerach, Marta Eugenia
author_role author
author2 Arias, Bárbara Soledad
Suarez, Mariana
Van Haute, Evert
Kovacec, Verónica Ivana
Lopardo, Horacio Angel
Bonofiglio, Laura
Mollerach, Marta Eugenia
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Urinary Tract infections
Streptococcus agalactiae
group B
Argenina
topic Urinary Tract infections
Streptococcus agalactiae
group B
Argenina
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Introduction: Streptococcus agalactiae (group B streptococcus, GBS) is a recognized urinary pathogen both in males and pregnant or non-pregnant women. Data regarding GBS serotypes recovered from urinary tract infections (UTIs) are scarce. The aim of this study was to describe the clinical and microbiological characteristics of UTIs caused by GBS in adult patients in Argentina.Methodology: A prospective multicenter study involving 86 centers was conducted in Argentina between July 1st, 2014 and June 30th, 2015. Antimicrobial susceptibility and serotype distribution of GBS isolated from the urinary tract of adult patients were determined. Susceptibility tests were performed by the disk diffusion and/or agar dilution methods. Epidemiological and clinical characteristics of the patients were considered to identify associated comorbilities.Results: Seven hundred and one GBS were sent to the reference laboratory in the above mentioned period, however, only 211 fulfilled our selection criteria (demographic data availability, underlying diseases reported, colony counts greater than 105 CFU/mL, single organism isolated from the urine sample). No penicillin-resistant GBS was found but fluoroquinolone resistance was high (12.8%), especially among GBS isolated from men and non-pregnant women. UTIs due to GBS were associated to underlying diseases in men and non-pregnant women, particularly diabetes mellitus. Most of the isolates showed serotypes Ia and III.Conclusions: GBS are still susceptible to penicillin but fluoroquinolone resistance is a growing concern, at least in Argentina. There are underlying conditions that could be associated to urinary infections caused by GBS.
Fil: Vigliarolo, Laura. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; Argentina
Fil: Arias, Bárbara Soledad. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Microbiología; Argentina
Fil: Suarez, Mariana. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; Argentina
Fil: Van Haute, Evert. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Microbiología; Argentina
Fil: Kovacec, Verónica Ivana. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Microbiología; Argentina
Fil: Lopardo, Horacio Angel. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; Argentina
Fil: Bonofiglio, Laura. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Microbiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Fil: Mollerach, Marta Eugenia. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Microbiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
description Introduction: Streptococcus agalactiae (group B streptococcus, GBS) is a recognized urinary pathogen both in males and pregnant or non-pregnant women. Data regarding GBS serotypes recovered from urinary tract infections (UTIs) are scarce. The aim of this study was to describe the clinical and microbiological characteristics of UTIs caused by GBS in adult patients in Argentina.Methodology: A prospective multicenter study involving 86 centers was conducted in Argentina between July 1st, 2014 and June 30th, 2015. Antimicrobial susceptibility and serotype distribution of GBS isolated from the urinary tract of adult patients were determined. Susceptibility tests were performed by the disk diffusion and/or agar dilution methods. Epidemiological and clinical characteristics of the patients were considered to identify associated comorbilities.Results: Seven hundred and one GBS were sent to the reference laboratory in the above mentioned period, however, only 211 fulfilled our selection criteria (demographic data availability, underlying diseases reported, colony counts greater than 105 CFU/mL, single organism isolated from the urine sample). No penicillin-resistant GBS was found but fluoroquinolone resistance was high (12.8%), especially among GBS isolated from men and non-pregnant women. UTIs due to GBS were associated to underlying diseases in men and non-pregnant women, particularly diabetes mellitus. Most of the isolates showed serotypes Ia and III.Conclusions: GBS are still susceptible to penicillin but fluoroquinolone resistance is a growing concern, at least in Argentina. There are underlying conditions that could be associated to urinary infections caused by GBS.
publishDate 2019
dc.date.none.fl_str_mv 2019-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/129342
Vigliarolo, Laura; Arias, Bárbara Soledad; Suarez, Mariana; Van Haute, Evert; Kovacec, Verónica Ivana; et al.; Argentinian multicenter study on urinary tract infections due to Streptococcus agalactiae in adult patients; The Journal of Infection in Developing Countries; The Journal of Infection in Developing Countries; 13; 1; 6-2019; 77-82
1972-2680
CONICET Digital
CONICET
url http://hdl.handle.net/11336/129342
identifier_str_mv Vigliarolo, Laura; Arias, Bárbara Soledad; Suarez, Mariana; Van Haute, Evert; Kovacec, Verónica Ivana; et al.; Argentinian multicenter study on urinary tract infections due to Streptococcus agalactiae in adult patients; The Journal of Infection in Developing Countries; The Journal of Infection in Developing Countries; 13; 1; 6-2019; 77-82
1972-2680
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://jidc.org/index.php/journal/article/view/32032027
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv The Journal of Infection in Developing Countries
publisher.none.fl_str_mv The Journal of Infection in Developing Countries
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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